82952.m00151

Species: T.vaginalis
Alias: 82952.m00151, TvagK0277
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
82952.m00151.AA Protein None 851 None Fasta, JSON
82952.m00151.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 82952.m00151.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82952.m00151.AA TKL 31-278 23 2.6e-67 229.91 In-house 1-364 (364) Show / Hide
Range on Protein: 31-278
Range on HMM: 1-364/364
Sequence Identity: 23% (89 aa)

IGKGGFGEVRRGINKQ--------TGRECAVKTIFAERLEGNRL-------------------------RRYIGEIETLAKCNNMFLVPFIG--FTPTP-
||.|||||| .|. ..        ||.. |||..  .    . .                          . . ||  . ...   .|.|.|  . |.. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-----------PYTIVTEFMPNGALDRYVRRKPGVAPLTGTQLTAIAIGIAHGMKNLHENG--------IIHRDLKAANILLDSRLF-------------
            . ||.|..|.| |  |.            |.  .|..|| ||  || ..        ||||||| .|||.|. .              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PRICDFGIARFEEHSAS-------------------GMTVKIGTPNYMAPELIQ----------------SGDYDGKVDVYAYAMILYEMSENTRPFNR
 . |||||..|| ..| .                       ..|||..||||...                ...|. |.|||.....|.|.    ||.  
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

MKVN---------EVFHAVVQHDERPEFT------------RATSPQMQKLITQCWDRDPSVRPTFNEIFDIF
.. .         | |  |... .||.                . |.| ||...||| ||. ||.|.|| ...
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase 82952.m00151.AA S_TKc 25-279 28 9.7e-60 205.7 SMART 1-231 (231) Show / Hide
Range on Protein: 25-279
Range on HMM: 1-231/231
Sequence Identity: 28% (76 aa)

FDYGDVIGKGGFGEVRRGINKQTGRECAVKTIFAERLEGNRLRRYIGEIETLAKCNNMFLVPFIGFTPTPPYTIVTEFMPN--GALDRYVRRKPGVAP--
.. ...||||.||.|.....| |||..|.| |          .. . ||. | | .  ..| ....  .  . .|.|....  | | .| .....  .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTGTQLTAIAIGIAHGMKNLHENGIIHRDLKAANILLDSRLFPRICDFGIARFEEHSASGMTVKIGTPNYMAPELIQSGDYDG-KVDVYAYAMILYEMS
 ..  .   ..  |. ... .|..|||||||| .|||||.     |||||.||.        |  .|||.|||||..    |.. |.|...   ||||| 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

ENTRPFNRMKVNEVFHAVVQHDERPEFTRATSPQMQKLITQCWDRDPSVRPTFNEIFD--------IFA
    ||    ....|. ..            ||..  .| .|...||. |||  |..          . 
CGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 82952.m00151.AA TKL-Unique 27-278 26 2.9e-55 189.93 In-house 1-290 (290) Show / Hide
Range on Protein: 27-278
Range on HMM: 1-290/290
Sequence Identity: 26% (78 aa)

YGDVIGKGGFGEVRRGINKQTGRECAVKTIFAERLEGNRLRR-YIGEIETLAKCN-NMFLVPFIGFTP----TPP-YTIVTEFMPNGALDRYVRR-----
 . .|| ||.|.| .|. ...  . |.|... . .  |....  . |. .. | .   ..| ..|..     .|| . ||.|..| | |. .  .     
FWNKIGEGGYGQVYKGKWRGY--PVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

--KPGVAPLTGTQLTAIAIGIAHGMKNLHENG--IIHRDLKAANILLDSR-----LFPRICDFGIARFEEHS---ASGMT------VKIGTPNYMAPELI
   .   .|.  |   .|| || || .|| ..  |||||||  |.|.|..     .  .|||||...|   .    ...       ...|....||||..
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

QS--GDYDGKVDVYAYAMILYEMSENTR------PFNRMKVNEVFHAVVQ--HDERPEFTRATSPQMQKLITQCWDRDPSVRPTFNEIFDIF
 .   .|. |.|||.....|.|. ....      |.  |  .... .| .     ||.      .. ..||.|||..||| ||.|.||    
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase 82952.m00151.AA Pkinase 25-278 26 3.8e-54 191.0 Pfam 1-293 (293) Show / Hide
Range on Protein: 25-278
Range on HMM: 1-293/293
Sequence Identity: 26% (78 aa)

FDYGDVIGKGGFGEVRRGINKQTGRECAVKTIFAERLEGNRLRRYIG--EIETLAKCNNMFLVPFIGFTPTPPYTI-VTEFMPNG----ALDRYVR--RK
.  | .||.|.||.|.....| ||.. |||.|  .. . . ... .   ||. ....|  . | ....  ....   |.|....|     | .|..  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PGVAPLTGTQLTAIAIGIAHGMKNLHENGIIHRDLKAANILLDSRLFP----RICDFGIARFE-EHSASGMTVKIGTPNYMAPELIQ-SGDYDGKVDVYA
 ..  ..  ..  ..  |. |.. .|..|||||||| .|||.|..  .    .|||||.|..  . . | ||.  |||.|||||.|. . .|. |||...
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

YAMILYEMSENTRPFNRM----KVNEVFHAVVQHDE-RPEFTRATS---------------------PQMQKLITQCWDRDPSVRPTFNEIFDI--F
.  |||||     ||       . ..  . ...  . ...| . ..                     . ....|. |...||. |||. .|.    |
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 82952.m00151.AA MLK 25-278 25 3.5e-52 179.3 In-house 1-291 (291) Show / Hide
Range on Protein: 25-278
Range on HMM: 1-291/291
Sequence Identity: 25% (75 aa)

FDYGDVIGKGGFGEVRRGINKQTG---RECAVKTIFA-------ERLEGNRLRRYIGEIETLAKCN-NMFLVPFIGFTPTP-P-YTIVTEFMPNGALDRY
..   .||.|.||.| .|  . .    .. ||| ..|       .  |   ... . .   | . | .   ..| |    | . . ||.|....| | ..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

VRR-KPGVA----------PLTGTQLTAIAIGIAHGMKNLHENG---IIHRDLKAANILLDS------RLFPRICDFGIARFEEHSASGMTVKIGTPNYM
 .  ... .            .  ..  .|  .|.||  ||..    |||||||  |||.|        .  .|||||..|.  .. . |. ..||. .|
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APELI---QSGDYDGKVDVYAYAMILYEMSENTRPFN-RMKVNEVFHAVVQHDERPEFTRATSPQMQKLITQCWDRDPSVRPTFNEIFDIF
||| |   ... |. |.||. ....|.||     |.   ..  ...  |... .||      .. . ||..|||. ||. ||.| .|  ..
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase 82952.m00151.AA STE 25-273 22 7.5e-47 161.97 In-house 1-350 (359) Show / Hide
Range on Protein: 25-273
Range on HMM: 1-350/359
Sequence Identity: 22% (79 aa)

FDYGDVIGKGGFGEVRRGINK------QTGRE---------CAVKTIFAERLE---------------GNRLRRYIGEIETLAKCN--NMFLVPFIGFTP
..  ..||||.||.| ...|.      .||..         .|.| .  |. .                . . ... ||... |||    . | ..|   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TPP--------YTIVTEFMPNGALDRYVRRKPGVA-PLT----------GTQLTAIAIGIAHG-MKNLHENGIIHRDLKAANILLDSRLFPRICDFGIAR
             |. |.|..| ||  ...| |.  ||.           .|. .|.  | .| .. ||...|||||.|.|||||       .||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

-FEEHSA--------------SGMT-VKIGTPNYMAPELIQS------GDYDGKVDVYAYAMILYEMSENTRPFNRMKVNEVFHAVVQH-----------
 .....|              ....   .||| .|||| ||       ..|| |.|..     . || .   |.  |.  ..  .  .            
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---DERPEFTRATS-------------------PQMQKLITQCWDRDPSVRPTFNE
   .. | .   .|                   | ..  | .| ..||. ||| ..
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ

Kinase 82952.m00151.AA Dicty5 98-282 35 1.5e-45 154.76 In-house 76-260 (260) Show / Hide
Range on Protein: 98-282
Range on HMM: 76-260/260
Sequence Identity: 35% (67 aa)

IVTEFMPNGALDRYVR--RK-PGVAPLTGTQLTAIAIGIAHGMKNLHENGIIHRDLKAANILLDSRLFPRICDFGIARFEEHSASGMTVKIGTPNYMAPE
.|||.  || |  | .  ||  |  .. ..||  .||.|| .|. ||  .|||||||  |.|.  ..   | |||. || .  . .||. .||...||.|
HVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQL-HMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDN-RYHMTMHVGTQCWMACE

LIQSGDYDGKVDVYAYAMILYEMSENTRPFNRMKVNEVFHAVVQHDERPEFTRATSPQMQKLITQCWDRDPSVRPTFNEIFDIFASGK
| ..  |. |.|||... .|.||     |.  .   .     |.  |||.          .||  ||   |. ||.| || ..| |  
LFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNI-PVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII

Kinase 82952.m00151.AA Dicty4 98-280 34 4e-45 148.54 In-house 79-277 (277) Show / Hide
Range on Protein: 98-280
Range on HMM: 79-277/277
Sequence Identity: 34% (69 aa)

IVTEFMPNGALDRYVRRKP----GVAPLTGTQLTA---IAIGIAHGMKNLHE-N-GIIHRDLKAANILLDSRLFPRICDFGIAR----FEEHSASGMTVK
||||.|| | | .  . ||       .|  .  ..   .|. .| ||  ||. |  |||||||..|.| |  .   .||||...     |.|..  ||..
IVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTAC

IGTPNYMAPELIQSGDYDGKVDVYAYAMILYEMSENTRPFN--RMKVNEVFHAVVQHDERPEFTRATSPQMQKLITQCWDRDPSVRPTFNEIFDI--FAS
 ||| .||||  ..  |..|.||| ....|.|.     |..   |   ... ||... .||.    ..|   .||. ||| ||..||.|.||  .    .
-GTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH





Kinase 82952.m00151.AA TyrKc 25-278 25 8e-45 156.15 SMART 1-280 (280) Show / Hide
Range on Protein: 25-278
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

FDYGDVIGKGGFGEVRRGINKQTGRECAVKTIFAERLEGNRLRRYIGEIETLAKC--NNMFLVPFIGFTPT--------PPYTIVTEFMPNGALDRYVRR
   |...| | ||||..|. |   ...|||.. ..      ..  . |.. . |   ..  .| ..|   .        .|. ||.|.||.|.|. | |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KPGVAPLTGTQLTAIAIGIAHGMKNLHENGIIHRDLKAANILLDSRLFPRICDFGIARFEEHS----ASGMTVKI----GTP-----NYMAPELIQSGDY
. .   |.  .|  ... || ||  ||....||||| | |.|.....  .|.||| .|. ..     .|. . .     |.        |||| |. | .
HRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

DGKVDVYAYAMILYEMSENTRPFNRM-----KVNEVFHAVVQHDERPEFTRA--------TSPQMQKLITQCWDRDPSVRPTFNEIFDIF
  | ||...   ..|.  .  .         . |.  .. |.. .|..             .. | ....|||..||. ||||.|| ..|
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 82952.m00151.AA LRRK 95-280 29 2.5e-44 153.57 In-house 129-351 (351) Show / Hide
Range on Protein: 95-280
Range on HMM: 129-351/351
Sequence Identity: 29% (66 aa)

PYTIVTEFMPNGALDRYVRRKPGVA------PLTGTQLTAIAIGIAHGMKNLHENG--IIHRDLKAANILL---D---------SRLFPRICDFGIAR-F
|...|.|..|.|.|... . |   .       .. . .  ||. || ||. || .   |||||||  ||||   .               |.|||| | |
PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF

EEHSASG-MTVKIGTPNYMAPELIQSG---DYDGKVDVYAYAMILYE-MSENTRPFNRMK-V-----NEVFHAVVQHDERPEFTRA-TSP-----QMQKL
     .|    . |.| .|||| .. .    |. |||.|...|||.| ..   .||  .. .     .| .   ..   || .      |      .|.|
-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDL

ITQCWDRDPSVRPTFNEIFDIFAS
|..||. ||  ||.|..|...  .
IQHCWQHDPKKRPHFSQIVKRLSQ

Kinase 82952.m00151.AA Pkinase_Tyr 25-278 29 1.5e-43 148.16 Pfam 1-270 (270) Show / Hide
Range on Protein: 25-278
Range on HMM: 1-270/270
Sequence Identity: 29% (79 aa)

FDYGDVIGKGGFGEVRRGINK----QTGRECAVKTIFAERLEGNR--LRRYIGEIETLAKC-NNMFLVPFIGFTP--TPP--YTIVTEFMPNGALDRYVR
   | ..|.| ||||..|. |    .|. ..|||..  |        ..  . |.... .  ..  .| ..|       |  . ||.|.||.| |. | |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

RK-PGVAPLTGTQLTAIAIGIAHGMKNLHENGIIHRDLKAANILLDSRLFPRICDFGIARFE-EHSASGMTVKIGTP---NYMAPELIQSGDYDGKVDVY
.. ..  |||  .|  ... || ||  |.....||||| | |.|... .. .||||| ||   . .   .... |..     |||| |. | .  | ||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW

AYAMILYEMSENT-RP-FNRMKVNEVFHAVVQHDERPEFTRATSPQMQKLITQCWDRDPSVRPTFNEIFDIF
..   ..|.      | .  |. .||.... .. .| .  . ... . .|..|||. ||. |||| ||  ..
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase 82952.m00151.AA TK 25-278 14 4.1e-43 141.9 In-house 1-486 (486) Show / Hide
Range on Protein: 25-278
Range on HMM: 1-486/486
Sequence Identity: 14% (71 aa)

FDYGDVIGKGGFG---EVRRGINKQTG-------------------------RECAVKTIFAERLEGNRLRRY---------------IGEIETLA--KC
  .|...|.| ||   ||..|. .. .                          ..|||.. ..  .  . ..                  |.. .   ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

NNMFLVPFIG-FTPT------------PPYTIVTEFMPNGA----LDRYVR--RKPGVA-----------------------------------------
.   .| ..|  |              .|. ||.|.||.|     |. | |  |...                                           
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------PLTGTQLTA-------------------IAIGIAHGMKNLHEN------GIIHRDLKAANILLDSRLF-----------PRICDFGIA--
          ||| ..|                     ..  || ||  ||..      ...|||| | |.|.....             .|.||| .  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----RFEEHSASGMTVKIGTPN----------------------------YMAPELIQ---------SGDYDGKVDVYAYAMILYEMSENT-RPFNRMKV
    .  ..  ..  .. ...                             .|||| ..          | .  | ||...   ..|.  .   |.  .  
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

N----------EVFHAVVQ-------------HDERPEFTRATS--------------PQMQKLITQCWDRDPSVRPTFNEIFDIF
|          ||.  ...             .  |..     .              . .. |..|||..||. |||| .. . .
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase 82952.m00151.AA Dicty4-Unclassified 20-278 32 1.1e-42 144.02 In-house 1-263 (263) Show / Hide
Range on Protein: 20-278
Range on HMM: 1-263/263
Sequence Identity: 32% (89 aa)

LNLDDFDYGDVIGKGGFGEVRRGINKQTGRECAVKTIFAERLEGNR---LRRYIGEIETLAKCNNMFLVPFIGFTPTP-----PYTIVTEFMPNGALDRY
.  | |     |||| | .| .|. |  |.. ||| .| |     |   .  .  |.| |       ||   |    |      . ||.|||. | |   
IQIDQF-----IGKGHFSKVHKGNWK--GKDVAVK-KFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEV

VR----RKPGVAPLTGTQLTAIAIGIAHGMKNLHENGIIHRDLKAANILLDSRLFPRICDFGIARFEEHSASGMTVKIGTPNYMAPELIQSGDYDGKVDV
.      .     |  |   ..|. || ||  ||   .||||.|..|||.|     .| ||||.| .      ||   |||   .||      |  | ||
IHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISR-VIDFNFNMTTIAGTPKWESPECLMHESYNQKSDV

YAYAMILYEMSENTRPFNRMK-VNEVFHAVVQHDERPEFTRATSPQMQKLITQCWDRDPSVRPTFNEIFDIF
| |||.|||.     |.     . ..   |     ||.      . ..|||  ||  ||  |||.|.| .  
YSYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL

Kinase 82952.m00151.AA ULK 25-280 22 9.3e-40 136.48 In-house 1-329 (329) Show / Hide
Range on Protein: 25-280
Range on HMM: 1-329/329
Sequence Identity: 22% (73 aa)

FDYGDVIGKGGFGEVRRGINKQT----GRECAVKTIFAERLEGNRLRRY-------IG-EIETLAKCN--------NMFLVPFIGFTPTP---PYTIVTE
.   ...||| || | .|.||.|    .  .|.| |  . .  .   ..       .  ||... | .        .   | .. .. |.    . |..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FMPNGALDRYVRRKPG--VAP-----LTGTQLTAIAIGIAHGMKNLHENGIIHRDLKAANILLDSRLF------------PRICDFGIARFEEHS----A
. . | |. |  .. .          |.  .   . . |. |.| ||...|||||.| .|||..                  |.||| |.. . .    .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

SGMTVKI-----GTPNYMAPELIQ----SGDYD-GKVDVYAYAMILYEMSENTRPFNRMKVNEVFHAVVQHDER-------------PEFTRA-----TS
  || .      ||| ||||...|      .|.  |.|..   .|.|||  .  ||. .  |. ..  .|   .             ..|  .      |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PQMQKLITQCWDRDPSVRPTFNEIFDIFAS
|... || ..  .|.. | .. |.|...  
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 82952.m00151.AA LRRK 25-62 27 0.00058 9.89 In-house 1-37 (351) Show / Hide
Range on Protein: 25-62
Range on HMM: 1-37/351
Sequence Identity: 27% (11 aa)

FDYGDVIGKGGFG-EVRRGINK-QTGRECAVKTIFAERLE
. ..  ||.|||| .| |.. . |..   .|..... .|.
LKIEEQIGRGGFGTFVYRAKWRGQPV---HVCRMHQKMLQ

Kinase 82952.m00151.AA Dicty4 25-54 46 0.02846 3.58 In-house 1-28 (277) Show / Hide
Range on Protein: 25-54
Range on HMM: 1-28/277
Sequence Identity: 46% (14 aa)

FDYGDVIGKGGFGEVRRGINKQTGRECAVK
 . .. ||||.|||| .|. .  | | |||
INIEQRIGKGSFGEVYKGTWR--GKEVAVK