Gene 90925.m00121 (T.vaginalis)

90925.m00121

Species: T.vaginalis
Alias: TvagK0314, 90925.m00121
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
90925.m00121.AA Protein None 779 None Fasta, JSON
90925.m00121.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 90925.m00121.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90925.m00121.AA TKL 206-450 27 1.8e-82 280.3 In-house 1-364 (364) Show / Hide 
Range on Protein: 206-450
Range on HMM: 1-364/364
Sequence Identity: 27% (101 aa)

IGGGVSSVVYYGRDKR--------TGNEVAIKKFKFKRLNGPRL-------------------------QSYQREAAVLANANHPALLHLVGVTDKIP--
|| | ...|| |. .         ||..||.|||| .  .   .                         .   .|. .. . .|| .....|.   .|  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FCIIMEWMPNHSLYHDLHSYHHLDATGRSIT-LYDIARGMQFLHNRQ--------IVHRDLKSLNVLLDKDDR--------------I
            .||.||..|. ||.|.||         . .   .||||||..||...        |.|||||| |.|.|.. .              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

RICDFGFSRHATDTTFMKHN--------------------IGTPHWMAPEVLQTN---------------GRYTSKIDVYAFAIVAWEIAVGKVPYQGMD
 |||||.||  . .. |...                    .||| |||||||. .               . |. |.|||.|.|| |||. ...||....
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

SNSII---------HQVLNNDLRPQIP------------EDLNPPMRDLITMCWERDPDIRPTFDEIVKRL
....|          .| .. ||| ||            .|  |.|..|...||. ||. ||.|.||.|||
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 90925.m00121.AA TKL-Unique 203-450 35 3.3e-78 266.12 In-house 2-290 (290) Show / Hide 
Range on Protein: 203-450
Range on HMM: 2-290/290
Sequence Identity: 35% (103 aa)

IKEIGGGVSSVVYYGRDKRTGNEVAIKKFKFKRLNGPRLQSYQ---REAAVLANAN-HPALLHLVGVTD----KIP-FCIIMEWMPNHSLYHDLH-----
.. ||.|....|| |  ...  .||||.|..  ........ |   .|  .. . . || ..|..|..     ..| .||.|| .|  |||  ||     
WNKIGEGGYGQVYKGKWRGY--PVAIKQFHP--NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNN

-----SYHHLDATGRSITLYDIARGMQFLHNRQ--IVHRDLKSLNVLLDKD-----DRIRICDFGFSRHAT--DTTFMK--------HNIGTPHWMAPEV
     . . |.   |     |||.|| .||...  | ||||||.|.|.| .      .|.|||||.|. ..  .... .         ..|.. ||||||
NNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

LQTN-GRYTSKIDVYAFAIVAWEIAVGKV------PYQGMDSNSIIHQVLN--NDLRPQIPEDLNPPMRDLITMCWERDPDIRPTFDEIVKRL
|  |   |. |.|||.|.|| |||| .|.      ||||||.....  |      .|| ||.....  ||||..|| .||..||.||||..||
LRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 90925.m00121.AA LRRK 200-452 26 1.4e-70 240.81 In-house 1-351 (351) Show / Hide 
Range on Protein: 200-452
Range on HMM: 1-351/351
Sequence Identity: 26% (94 aa)

FEEIKEIGGGVSS-VVYYGRDK--------------------------RTGNEVAIKKFKFKR---------------LNG-----------------PR
... ..|| |..  .|| .. .                          . ...|||||... .               ||.                   
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LQSYQREAAVLANANHPALLHLVGVTDKIPFCIIMEWMPNHSLYHDLHSYHHLD-----AT-GRSITL---YDIARGMQFLHNRQ--IVHRDLKSLNVLL
......|.... . ||| .. |.|.. . |.|..|| .|. .||| ||....       |  .....|   ..||.||..||..   |.|||||| |.||
FREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

DKDD------------RIRICDFGFSR--HATDTTFMKHNIGTPHWMAPEVLQTN--GRYTSKIDVYAFAIVAWEIAVGK-VPYQGMD----S--NSIIH
 . .             . |.||| ||   .. ... |   |.| |||||... |    || |.|.|.|... ||.  ..  |....|    .  ...| 
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE

QVLNNDLRPQIPED-LNP-----PMRDLITMCWERDPDIRPTFDEIVKRLST
.  .. ||| ||..  .|      . |||. ||. ||. ||.| .||||||.
DKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 90925.m00121.AA MLK 200-450 30 6.4e-67 228.64 In-house 1-291 (291) Show / Hide 
Range on Protein: 200-450
Range on HMM: 1-291/291
Sequence Identity: 30% (89 aa)

FEEIKEIGGGVSSVVYYGRDKRTGNE-----VAIKKFKFKR----LNGPRLQSYQREAAVLANANHPA----LLHLVGVTDKI-P-FCIIMEWMPNHSLY
... . || | . .|.  . .  ...     ||.|....        .   .  ..|.  |.  .||        ..||  .  . |||.||.... |||
IQFHEWIGSGSFGKVW--KGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

HDLHSYHH--------------LDATGRSITLYDIARGMQFLHNRQ---IVHRDLKSLNVLLD------KDDRIRICDFGFSRHATDT-TFMKHNIGTPH
. ||.                  |        ...||||..||. .   |.|||||| |.|.|      ...  .||||| ||  ... | |  |.||. 
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYA

WMAPEVLQ--TNGRYTSKIDVYAFAIVAWEIAVGKVPYQ-GMDSNSIIHQVLNNDLRPQIPEDLNPPMRDLITMCWERDPDIRPTFDEIVKRL
||||||.|   ...|. | ||. ...| ||.  ..|||. ..|.  |. .| .| ||| || . ....  |...||. ||  ||.|..||. |
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 90925.m00121.AA Pkinase 200-450 24 1.2e-64 225.91 Pfam 1-293 (293) Show / Hide 
Range on Protein: 200-450
Range on HMM: 1-293/293
Sequence Identity: 24% (73 aa)

FEEIKEIGGGVSSVVYYGRDKRTGNEVAIKKFKFKRLNGPRLQSYQR--EAAVLANANHPALLHLVGVT-DKIPFCIIMEWMPNH----SLYHDLH--SY
.. .. || | ...|| ...| || .||.|..| .. .   .|.  |  |...... |||  . | ..  ||   ...||....     .|.. ..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

HHL--DATGRSITLYDIARGMQFLHNRQIVHRDLKSLNVLLDKDDRI----RICDFGFSRH--ATDTTFMKHNIGTPHWMAPEVLQTNGRYTSKIDVYAF
  .  .       .| |.||....|.. |.|||||. |.|.|... |    .|||||....      . |..  |||..|||||....  |..|.|....
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

AIVAWEIAVGKVPYQGM------DSNSIIHQVLNNDLRPQIPEDLN-------------------PPMRDLITMCWERDPDIRPTFDEIVKR--L
 .. .| . |. |..|       | . .| ...  .|. ..|.. .                   ....|.|. |...||  |||...|..   .
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 90925.m00121.AA Dicty4 204-452 36 1.8e-63 210.62 In-house 5-277 (277) Show / Hide 
Range on Protein: 204-452
Range on HMM: 5-277/277
Sequence Identity: 36% (100 aa)

KEIGGGVSSVVYYGRDKRTGNEVAIKKFKFKRLN--GPRLQSYQREAAVLANANHPALLHLVGVTD---KIP--FCIIMEWMPNHSLYHDLHS-------
..||.|  . || |. .  | |||.||.. .  |    .|..  .|.. ...  || .. . |       .|  .|| .| ||  .||  ||.       
QRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ

YHHLD-ATGRS---ITLYDIARGMQFLHNRQ--IVHRDLKSLNVLLDKDDRIRICDFGFSR---HATDTTF-MKHNIGTPHWMAPEVLQTNGRYTSKIDV
   ||  . ..   . . |.||||. ||..   |.|||||| | | ||. |. .||||.|.     .| .. ..  .||| ||||||.. . .|..| ||
SIKLDWPLIKRAMRMAF-DAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQ-PYNEKADV

YAFAIVAWEIAVGKVPYQ--GMDSNSIIHQVLNNDLRPQIPEDLNPPMRDLITMCWERDPDIRPTFDEIVKR--LST
| |.|| |||. .. |||  .|.   ..  | |  ||| || .  |. ..||. ||. ||  ||.| ||..|  | .
YSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 90925.m00121.AA S_TKc 200-451 26 9.6e-62 212.36 SMART 1-231 (231) Show / Hide 
Range on Protein: 200-451
Range on HMM: 1-231/231
Sequence Identity: 26% (70 aa)

FEEIKEIGGGVSSVVYYGRDKRTGNEVAIKKFKFKRLNGPRLQSYQREAAVLANANHPALLHLVGVTDKIPFCIIMEWMPN--HSLYHDLHSYHH-----
.| ...|| |  ..|| .|.|.|| .||||. |         .. .|| ..| . .|| . .| .| .   ....|| ...   .|.. .... .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LDATGRSITLYDIARGMQFLHNRQIVHRDLKSLNVLLDKDDRIRICDFGFSRHATDTTFMKHNIGTPHWMAPEVLQTNGRYTS-KIDVYAFAIVAWEIA
 ..       .| |.......|...|.|||||  |.|||.  .| |||||..|.       .. .|||..||||||     |.  |.|.... .. .| .
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

VGKVPYQGMDSNSIIHQVLNNDLRPQIPEDLNPPMRDLITMCWERDPDIRPTFDEIVK--------RLS
.|. |..  . . ......             |...|.|  |...||. |||  |. .           
CGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 90925.m00121.AA STE 200-445 21 3.1e-55 189.81 In-house 1-350 (359) Show / Hide 
Range on Protein: 200-445
Range on HMM: 1-350/359
Sequence Identity: 21% (78 aa)

FEEIKEIGGGVSSVVYYGRDK------RTGNE---------VAIKKFKFKRLN---------------GPRLQSYQREAAVLANAN--HPALLHLVGVTD
.| |..|| | . .||.....      .||..         .|||. .... |                  .|....|  .. . |  ||   .  |   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KIP--------FCIIMEWMPNHSLYHDLHSY--------------HHLDATGRSITLYDIARG-MQFLHNRQIVHRDLKSLNVLLDKDDRIRICDFGFSR
|           .|.||.|.. ||   ....              |... .  .. ...| .| ...||. .|.|||.|. |.||     . .||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

HATD---------------TT--FMKHNIGTPHWMAPEVLQT-----NGRYTSKIDVYAFAIVAWEIAVGKVPYQGMDSNSIIHQVLNN-----------
  ||               |.    .. .||| ||||||.|      .. |. | |.. . ....| | ||.|.  |   . . . ..|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---DLRPQIPEDLN-------------------PPMRDLITMCWERDPDIRPTFDE
   .  |..|..|                    |...| |  | ..||. ||| ..
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 90925.m00121.AA Dicty4-Unclassified 203-450 35 5.9e-53 179.69 In-house 4-263 (263) Show / Hide 
Range on Protein: 203-450
Range on HMM: 4-263/263
Sequence Identity: 35% (95 aa)

IKEIGGGVSSVVYYGRDKRTGNEVAIKKFKFKRLNGPR---LQSYQREAAVLANANHPALLHLVGVTDKIP------FCIIMEWMPNHSLYHDLHSYHHL
 ..|| |  | |. |  |  | .||.|||   .    |   .| . .| ..|    || |. . |     |      .||.|| |.   |    ||    
DQFIGKGHFSKVHKGNWK--GKDVAVKKFNENKFKF-REEMIQDFKKEVEILGSIQHPNLVKCYGYC-INPRSHKSTMCIVMEFMHKGNLFEVIHS--KP

DATGRSITLYD---------IARGMQFLHNRQIVHRDLKSLNVLLDKDDRIRICDFGFSRHATDTTFMKHNIG-TPHWMAPEVLQTNGRYTSKIDVYAFA
    ..| | |         ||.|||.|| | ..|||.|| |.|.||.  |.| ||| ||  .| .|    |. || | .||.|     |..| ||| .|
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISR-VIDFNFNMTTIAGTPKWESPECLMHES-YNQKSDVYSYA

IVAWEIAVGKVPYQGMD-SNSIIHQVLNNDLRPQIPEDLNPPMRDLITMCWERDPDIRPTFDEIVKRL
.. .| | |  |||.      .   |    |||.||.   . .. ||  ||  ||  |||...|...|
MMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 90925.m00121.AA DRK 223-452 36 1.7e-52 176.11 In-house 22-258 (258) Show / Hide 
Range on Protein: 223-452
Range on HMM: 22-258/258
Sequence Identity: 36% (87 aa)

GNEVAIKKFKFKRLN-GPRLQSYQREAAVLANANHPALLHLVGVTDKIP-FCIIMEWMPNHSLYHDLHSYH-HLDATGRSITLYDIARGMQFLHNRQ--I
| .||.|. .    |    |.  .||. .. .  ||      |     |  ||.|| ||  |||  ||     .|   .     |.|.|| .||..   |
GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPII

VHRDLKSLNVLLDKDDRIRICDFGFSR---HATDTTFMKHNIGTPHWMAPEVLQTNGRYTSKIDVYAFAIVAWEIAVGKVPYQGMDSNSIIHQVLNNDLR
.|||||| | | |   .. . ||| |       . .| .  .||| | |||||  | ||| | ||| |||| ||..  . ||.||    ..  |    .|
IHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLR-NQRYTEKADVYSFAIVLWECVTRQDPYFGMPTFQVVFSVGRHGMR

PQIPEDLNPPMRDLITMCWERDPDIRPTFDEIVKRLST
| .|.   |.   |.. ||. ||  ||...|...||  
PPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase 90925.m00121.AA TK 200-450 16 3.5e-51 169.44 In-house 1-486 (486) Show / Hide 
Range on Protein: 200-450
Range on HMM: 1-486/486
Sequence Identity: 16% (81 aa)

FEEIKEIGGGVSS---VVYYG------RDKRTGN-------------------EVAIKKFKFKRLNGPRLQSY---------------QREAAVLAN--A
 . .|..| |      .|| |      ... ...                   .||.|  | .  . .. .                  .|.... .   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

NHPALLHLVG-VTDK------------IPFCIIMEWMPNHS----LYHDLHSYHHLDATGRS--------------------------------------
.|| ...|.| .|..             |..|.||.||. .    | . |.. ..   .  .                                      
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------ITL------YDIARGMQFLHNR------QIVHRDLKSLNVLLDKDDR-----------IRICDFG----
                               .|.      ..||.||..|| .      ..|||||   |.|......           ..|.|||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----FSRHATD--TTFMKHNIGTPH-------------------------WMAPEVLQT--------NGRYTSKIDVYAFAIVAWEIAV-GKVPYQGMDS
     .|   .      |.. ||.                          |||||.|..        .|..|.| ||..| .. |||   |..|| |. |
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

N---------SIIHQVLNND--------------LRPQIPEDLN--------------PPMRDLITMCWERDPDIRPTFDEIVKRL
|           . . | .               .|.  |..                . . ||...||..||. ||||......|
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 90925.m00121.AA TKL-ciliate1 204-450 28 2.5e-49 167.01 In-house 5-279 (279) Show / Hide 
Range on Protein: 204-450
Range on HMM: 5-279/279
Sequence Identity: 28% (80 aa)

KEIGGGVSSVVYYGRDKRTGNEVAIKKFKFKRLNG--PRLQSYQREAAVLAN-ANHPALLHLVGVTDK-IPFCIIMEWMPNHSLYHDLHSYHH----LDA
..|| | .. || || .    .|||.. .   ..     .  .|||   . .  .|  |. |.|.  .   | ||||  .  ..   .|  |     .  
QKIGSGHFCNVYKGRCNSY--DVAIMNMNYFNSQESFINQKEFQREIQQHIKIKQHINLQQLQGISFYDNNFYIIMEHCHKGTMFDICHRKHSQIYMIKW

TGRSITLYDIARGMQFLHNRQ--IVHRDLKSLNVLLDKDDRIRICDFGFSRH-------ATDTTFM---KHNIGTPHWMAPEVL----QTNGRYTSKIDV
  |   ..|||.|||.|| ||  ..|||||..| |.|.. .  ||.|.             .   |       .|.||||||..    . |  .. |||.
QHRMRWCKDIAQGMQYLHMRQNPLIHRDLKMQNILYDEPYQYKICNFPHVKIADFHRIRNCSFQDMQNEMQRNTTFHWMAPEQMDPHIFPNYPINEKIDI

YAFAIVAWEIAVGKVPY-QGMDSNSIIHQVLNNDLRPQI-----PEDLNPPMRDLITMCWERDPDIRPTFDEIVKRL
||..||... .  | |. | |   .|.  .     ||       . |  . . .|.  ||...|  || |.||  .|
YAYGIVMYILCFRKTPFQQKMSVINIMCYWCEFPGRPNLGPQFIHFDCPQNFHNLMMRCWCQNPNKRPNFNEIIQIL
Kinase 90925.m00121.AA Pkinase_Tyr 200-450 29 7.8e-48 162.62 Pfam 1-270 (270) Show / Hide 
Range on Protein: 200-450
Range on HMM: 1-270/270
Sequence Identity: 29% (81 aa)

FEEIKEIGGGVSSVVYYGRDK----RTGNEVAIKKFKFKRLNGPR---LQSYQREAAVLANA-NHPALLHLVGV-T-DKIP--FCIIMEWMPNHSLYHDL
 . .|..| |   .|| |. |     |. .||.|.   |    ..   ...  |||... .  .|| .. |.|| | .. |   .|.|| ||. .|.. |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

HSY----HHLDATGRSITLYDIARGMQFLHNRQIVHRDLKSLNVLLDKDDRIRICDFGFSRHA-----TDTTFMKHNIGTPHWMAPEVLQTNGRYTSKID
..     ..|.        ..||.||..|......||||   |.|....  ..||||| .|         ..  ..      |||||.....  .|.| |
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGK-FTTKSD

VYAFAIVAWEIAV-GKVP-YQGMDSNSIIHQVLNNDLRPQIPEDLNPPMRDLITMCWERDPDIRPTFDEIVKRL
|..| .. |||   |. | |.||. . .....  .  |  .||.  ... ||...||. ||. |||| ||. .|
VWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 90925.m00121.AA TyrKc 200-450 28 1.1e-46 162.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 200-450
Range on HMM: 1-280/280
Sequence Identity: 28% (82 aa)

FEEIKEIGGGVSSVVYYGRDKRTGNEVAIKKFKFKRLNGPRLQSYQREAAVLANA--NHPALLHLVGVTDK--------IPFCIIMEWMPNHSLYHDLHS
 . .|..| |   .|| |. |    .||.|. |        ..   ||| .. .   .|| .. |.||  .         | .|.|| ||. .| . |..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

YHH-LDATGRSITLYDIARGMQFLHNRQIVHRDLKSLNVLLDKDDRIRICDFGFSRHATDT--------TFMK----HNI--GTPHWMAPEVLQTNGRYT
... |         ..||.||..|| ....||||   |.|.... ...|.||| ||  .|         . .|    .        |||||..   |..|
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

SKIDVYAFAIVAWEIA-VGKVPYQGM----DSNSIIHQVLNNDLRPQIPED--------LNPPMRDLITMCWERDPDIRPTFDEIVKRL
.| ||..| .. |||   |. || ||     ||. ... . .  |. .|..          . | .....||..||. |||| ||....
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF