Gene 95305.m00251 (T.vaginalis)
95305.m00251
Species: T.vaginalis
Alias: TvagK0343, 95305.m00251
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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95305.m00251.AA | Protein | None | 780 | None | Fasta, JSON |
95305.m00251.kin_dom | Protein Kinase Domain | None | 251 | None | Fasta, JSON |
Protein domains of 95305.m00251.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 95305.m00251.AA | TKL | 207-451 | 27 | 5.9e-86 | 291.86 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 207-451 Range on HMM: 1-364/364 Sequence Identity: 27% (102 aa) IGRGVSAHVYYGKHKR--------TGEYVAIKKFTFQK-----------------------LNSAKFQSDQREVAVLATAQ--HPALLRLIG-ATDSWP- ||.| .. || ||.. ||. ||.||| . . |.. ...|. .. . || .....| .... . IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG ------------FCIITEWMDGGSLYKAIHTPGHMNATLRTIAAFDIARGMQFLHSRK--------IVHRDLKSLNVLLDSNKK--------------VK .||..|...||||. .| .| | ||||||..|||.. |.|||||| |.|.|.| . .| CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK ICDFGFSRFAEQSTEMTSN--------------------IGTPHWMAPEVLK---------------RGSRYTSKVDVYAYGVLLWELLTSETPYDGFGS |||||.||| .||..|. . .||| |||||||. .|. |. |.|||..|..|||.|| ..||..... ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY QQII---------SEVLNFDARPHLP------------EQGNMAMRDLITLCWDRDPNTRPNFDDIVKLF ..| . | . || .| .. |..|.. ||| ||. ||.|..|.| . MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | 95305.m00251.AA | TKL-Unique | 204-451 | 34 | 3e-79 | 269.57 | In-house | 2-290 (290) | Show / Hide |
Range on Protein: 204-451 Range on HMM: 2-290/290 Sequence Identity: 34% (100 aa) IKEIGRGVSAHVYYGKHKRTGEYVAIKKFTF-QKLNSAKFQSDQREVAVLATAQ-HPALLRLIGATD----SWP-FCIITEWMDGGSLYKAIH------- .. ||.|... || ||.. |. ||||.| . .... . | .|| .. . . || .....|.. . | .||..| ..|||||. .| WNKIGEGGYGQVYKGKWR--GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN --TPGH-MNATLRTIAAFDIARGMQFLHSRK--IVHRDLKSLNVLLDSN-----KKVKICDFGFSRFAEQSTEMTSN----------IGTPHWMAPEVLK . . .| .| | |||.|| .||... | ||||||.|.|.|.| ..||||||.|.|. ....||.| .|.. |||||||. NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR RG-SRYTSKVDVYAYGVLLWELLTSET------PYDGFGSQQIISEVLN--FDARPHLPEQGNMAMRDLITLCWDRDPNTRPNFDDIVKLF . . |. |.|||..|. |||..|.. ||.|. ..|... | || .|. . ||||. ||..|| ||.||.|.. MNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL |
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Kinase | 95305.m00251.AA | MLK | 201-451 | 31 | 2.8e-77 | 263.04 | In-house | 1-291 (291) | Show / Hide |
Range on Protein: 201-451 Range on HMM: 1-291/291 Sequence Identity: 31% (92 aa) FEEIKEIGRGVSAHVYYGKHKRTG---EYVAIKKFTFQK----LNSAKFQSDQREVAVLATAQHPA----LLRLIGATDSW-P-FCIITEWMDGGSLYKA ... . || | . |. |. . . ||.|.... . .. . ..|. |. .|| .. |. . . |||..|...||||| IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV IHT-PGHMN-----------ATLRTIA--AFDIARGMQFLHSRK---IVHRDLKSLNVLLDS------NKKVKICDFGFSRFAEQS-TEMTSNIGTPHWM .|. ... . .. .. |...||||..||| . |.|||||| |.|.| ....|||||| ||. |. | |.||.||. || LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM APEVL--KRGSRYTSKVDVYAYGVLLWELLTSETPYD-GFGSQQIISEVLNFDARPHLPEQGNMAMRDLITLCWDRDPNTRPNFDDIVKLF ||||. .|...|. |.||. .||.|||.|| |.||. . . .|. .| . ||..| . . . |.. ||. ||. ||.|. ||. . APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL |
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Kinase | 95305.m00251.AA | Pkinase | 201-451 | 27 | 1.4e-71 | 248.9 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 201-451 Range on HMM: 1-293/293 Sequence Identity: 27% (82 aa) FEEIKEIGRGVSAHVYYGKHKRTGEYVAIKKFTFQKLNSAKFQSDQR--EVAVLATAQHPALLRLIGAT-DSWPFCIITEWMDGG----SLYKAIH--TP .. .. ||.| .. || ..|| ||. ||.|.. .. .| | |.. | |..... .|| .||... |. ....|...|| .|. |. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GHM--NATLRTIAAFDIARGMQFLHSRKIVHRDLKSLNVLLDSNKKV----KICDFGFSRF--AEQSTEMTSNIGTPHWMAPEVLKRGSRYTSKVDVYAY | . . |.||....||..|.|||||. |.|.|.| . ||||||.... .. ||. |||..|||||.. |. |..|||.... GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVLLWELLTSETPYDGF------GSQQIISEVLNFDARPHLPEQGN-------------------MAMRDLITLCWDRDPNTRPNFDDIVKL--F |..|.|.|. ..|..| .|.| ... . . . |. . ...|.|. |...||. ||....|.. | GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | 95305.m00251.AA | LRRK | 201-453 | 26 | 2.1e-71 | 243.56 | In-house | 1-351 (351) | Show / Hide |
Range on Protein: 201-453 Range on HMM: 1-351/351 Sequence Identity: 26% (95 aa) FEEIKEIGRGVSA-HVYYGKHK--------------------------RTGEYVAIKKFTF--------------------------------QKLNSAK ... ..||||... || .| . . .. |||||... . . LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA FQSDQREVAVLATAQHPALLRLIGATDSWPFCIITEWMDGGSLYKAIH---TPG------HMNATLRTIAAFDIARGMQFLHSRK--IVHRDLKSLNVLL |.. ..||... . .|| .. |.| . . |.|...| .. |.||. .| | |.. .|. | .||.||..|||.. |.|||||| |.|| FREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL DSNK------------KVKICDFGFSR--FAEQSTEMTSNIGTPHWMAPEVLKRG--SRYTSKVDVYAYGVLLWELLTSE-TPYDGFG----S--QQIIS | . ..||.||| || .. ... |.| |||||... . . || |||.|..|..|||||| . |.|.. . . .|. WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE EVLNFDARPHLPEQ-GNM-----AMRDLITLCWDRDPNTRPNFDDIVKLFKQ . . || .|. . . |||..||. ||. || | .||| .| DKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ |
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Kinase | 95305.m00251.AA | Dicty4 | 205-453 | 34 | 1.4e-66 | 221.06 | In-house | 5-277 (277) | Show / Hide |
Range on Protein: 205-453 Range on HMM: 5-277/277 Sequence Identity: 34% (96 aa) KEIGRGVSAHVYYGKHKRTGEYVAIKKF--TFQKLNSAKFQSDQREVAVLATAQHPALLRLIGATD---SWP--FCIITEWMDGGSLYKAIHT------- ..||.| . || |. . | ||.||. . |.. .. .. .||. .. .|| .. . || | | .|| || | |.||. .| QRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ PGHMNATLRTI---AAFDIARGMQFLHSRK--IVHRDLKSLNVLLDSNKKVKICDFGFSR----FAEQSTEMTSNIGTPHWMAPEVLKRGSRYTSKVDVY . .|.. |||.||||. ||.. |.|||||| | | | |..||.||||.|. .... ... .||| ||||||. .. .|..|.||| SIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVM-MHQPYNEKADVY AYGVLLWELLTSETPYD--GFGSQQIISEVLNFDARPHLPEQGNMAMRDLITLCWDRDPNTRPNFDDIVKL--FKQ .| .|||.|| . || . |.. | | || .| .. ..||. ||| ||. || | |.. SFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH |
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Kinase | 95305.m00251.AA | S_TKc | 201-456 | 27 | 1.4e-65 | 225.05 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 201-456 Range on HMM: 1-231/231 Sequence Identity: 27% (73 aa) FEEIKEIGRGVSAHVYYGKHKRTGEYVAIKKFTFQKLNSAKFQSDQREVAVLATAQHPALLRLIGATDSWPFCIITEWMDG--GSLYKAIHTPGH----- .| ...||.| . || ..||.||..||||. .. .||...| .|| . .|... .. .....| .|| |.|.. |. |. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF -MNATLRTIAAFDIARGMQFLHSRKIVHRDLKSLNVLLDSNKKVKICDFGFSRFAEQSTEMTSNIGTPHWMAPEVLKRGSRYTS-KVDVYAYGVLLWELL .. . |.......||..|.||||| |.|||. .||||||..|. |. .|||..|||||| |. |.|... |..|.|.| PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML TSETPYDGFGSQQIISEVLNFDARPHLPEQGNMAMRDLITLCWDRDPNTRPNFDDIVK----LFKQGLV . ..|.. .| . ... ..|.| |...||. || .. . . . CGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 95305.m00251.AA | Dicty4-Unclassified | 204-451 | 35 | 5e-60 | 204.27 | In-house | 4-263 (263) | Show / Hide |
Range on Protein: 204-451 Range on HMM: 4-263/263 Sequence Identity: 35% (95 aa) IKEIGRGVSAHVYYGKHKRTGEYVAIKKFTFQKLNSAK---FQSDQREVAVLATAQHPALLRLIGATDSWP------FCIITEWMDGGSLYKAIH----- ..||.| . |. | | | ||.||| | .. | .||..| ||| |... |. | .||..| | | | || DQFIGKGHFSKVHKGNWK--GKDVAVKKFNENK-FKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCIN-PRSHKSTMCIVMEFMHKGNLFEVIHSKPSE --TPGHMNATLRTIAAFDIARGMQFLHSRKIVHRDLKSLNVLLDSNKKVKICDFGFSRFAEQSTEMTSNIGTPHWMAPEVLKRGSRYTSKVDVYAYGVLL | .. || |||||.|||.||.| ..|||.|| |.|.| . .|| ||| || . || ||| | .||.| .. |..| ||| |...| QQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECL-MHESYNQKSDVYSYAMML WELLTSETPYDGFG-SQQIISEVLNFDARPHLPEQGNMAMRDLITLCWDRDPNTRPNFDDIVKLF .||.| . || . . | || .|. .. || || ||| || ...|.. YELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL |
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Kinase | 95305.m00251.AA | Pkinase_Tyr | 201-451 | 29 | 4.2e-56 | 190.62 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 201-451 Range on HMM: 1-270/270 Sequence Identity: 29% (79 aa) FEEIKEIGRGVSAHVYYGKHK----RTGEYVAIKKFTFQKLNSAK--FQSDQREVAVLATA-QHPALLRLIGA-T-DSWP--FCIITEWMDGGSLYKAIH . .|..|.| .|| |. | |. ||.|. .. . .. ||.... . .|| ..||.|. | .. | .|..| | .|.|.. . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR T----PGHMNATLRTIAAFDIARGMQFLHSRKIVHRDLKSLNVLLDSNKKVKICDFGFSRFA---EQS-TEMTSNIGTPHWMAPEVLKRGSRYTSKVDVY . ... . ...||.||..|.|....|||| |.|...|..||||||| .| .. . .. |||||... | .|.| ||. KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVW AYGVLLWELLT-SETP-YDGFGSQQIISEVLNFDARPHLPEQGNMAMRDLITLCWDRDPNTRPNFDDIVKLF ..|||.||..| |.| | | .... . | || . ||...||. ||. || | .|. . SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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Kinase | 95305.m00251.AA | TK | 201-451 | 15 | 5.5e-56 | 185.81 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 201-451 Range on HMM: 1-486/486 Sequence Identity: 15% (76 aa) FEEIKEIGRGVSA---HVYYGKHKRTG-------------------------EYVAIKKFTFQKLNSAKFQSD---------------QREVAVLAT--A . .|..|.| || |. .. . . ||.| . .|.. . | .| ... ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG QHPALLRLIG-ATDS------------WPFCIITEWMDGGS----LYKAIHTPGH--------------------------------------------- .|| ..||.| |.. |..|..|.|..|. | . .. . HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY -------------------------------MNATLRTIAAFDIARGMQFLHSR------KIVHRDLKSLNVLLDSNKK-----------VKICDFG--- .. . ...||.||..|||. ..||||| |.|...|.. .||.||| DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR -----FSRFAEQSTEMTSNIGTPH---------------------------WMAPEVLKRGS--------RYTSKVDVYAYGVLLWELLT--SETPYDGF .| ..... .. . . |||||.|. . ..|.| ||...|||.||..| |..| | QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM GS---------QQIISEVLNF-------------DARPHLPEQGN--------------MAMRDLITLCWDRDPNTRPNFDDIVKLF . |... . . |. |.. .. ||.. ||..||. ||.|..... . SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | 95305.m00251.AA | DRK | 207-453 | 34 | 1.2e-55 | 186.98 | In-house | 7-258 (258) | Show / Hide |
Range on Protein: 207-453 Range on HMM: 7-258/258 Sequence Identity: 34% (89 aa) IGRGVSAHVYYGKHKRTGEYVAIKKFTFQKLNSAKFQSD-QREVAVLATAQHPALLRLIGA-TDSWPFCIITEWMDGGSLYKAIHTPG-HMNATLRTIAA |||| . |. | | ||.|. | .| .. .||. .. || .|. . . ||..| | ||||. | . | |. . IGRGNYGEVFRGTWR--GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMM FDIARGMQFLHSRK--IVHRDLKSLNVLLDSNKKVKICDFGFSR----FAEQSTEMTSNIGTPHWMAPEVLKRGSRYTSKVDVYAYGVLLWELLTSETPY ||.|.|| .||.. |.|||||| | | | . .||. ||| | .. . || .||| | ||||| | ||| | ||| ... |||..| . || FDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTM-CGTPCWTAPEVL-RNQRYTEKADVYSFAIVLWECVTRQDPY DGFGSQQIISEVLNFDARPHLPEQGNMAMRDLITLCWDRDPNTRPNFDDIVKLFKQ | |.. | || |... |.. ||. || || ...... FGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA |
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Kinase | 95305.m00251.AA | Dicty5 | 205-455 | 36 | 3.7e-54 | 184.8 | In-house | 5-260 (260) | Show / Hide |
Range on Protein: 205-455 Range on HMM: 5-260/260 Sequence Identity: 36% (94 aa) KEIGRGVSAHVYYGKHKRTGEYVAIKKFTFQKLNSAKFQSDQREVAVLATAQ--HPALLRLIGAT---DSWPFCIITEWMDGGSLYKAIHTPGH-----M . | | | || | | | |||| . .. .|||... | || . | || | || ..|| ||| . . DWIASGASGRVYNGIYK--GMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPF-HVTEYCHNGSLFNYLNDQRKTTGQPI NATLRTIAAFDIARGMQFLHSRKIVHRDLKSLNVLLDSNKKVKICDFGFSRFAEQSTEMTSNIGTPHWMAPEVLKRGSRYTSKVDVYAYGVLLWELLTSE .. | |||..|..||| |.||||||.|.|. | |.|| ||| ||| . .|| ..||. |||.|. . | |. |.|||..|. |||..| AYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFN-GQPYHQKCDVYSFGIVLWEMFTRK TPYDGFGSQQIISEVLNFDARPHLPEQGNMAMRDLITLCWDRDPNTRPNFDDIVKLFKQGL .||| . | | . || .| || || | || | |.| |.. EPYDNINNWNIPVMVMKGE-RPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII |
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Kinase | 95305.m00251.AA | STE | 201-446 | 21 | 4.1e-52 | 179.46 | In-house | 1-350 (359) | Show / Hide |
Range on Protein: 201-446 Range on HMM: 1-350/359 Sequence Identity: 21% (77 aa) FEEIKEIGRGVSAHVYYGKHKR---------------TGEYVAIKKFTFQKLNS---------------AKFQSDQREVAVLATAQ--HPALLRLIGAT- .| |..||.| . ||..... |||..|||. ... |. ..|. ..|. .. . || . .|. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF -----DSW--PFCIITEWMDGGSLYKAIH---TP-----------GHMNATLRTIAAFDIARG-MQFLHSRKIVHRDLKSLNVLLDSNKKVKICDFGFSR ... .|. |.|||||| . |. . .... .. . ...| .| ...||| .|.|||.|. |.|| ||.||||.. KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG FAEQ-----------------STEMTSNIGTPHWMAPEVLKR-GSR----YTSKVDVYAYGVLLWELLTSETPY-DGFGS---QQIISEVLNFD------ .. . . .. .||| ||||||... |. |. |.|.. | ...|..| . |. |. .|. . .. QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC ----ARPHLPEQGN-------------------MAMRDLITLCWDRDPNTRPNFDD | ||. ..| | .| ..||| ||. .. IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ |
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Kinase | 95305.m00251.AA | TyrKc | 201-451 | 27 | 1e-49 | 172.39 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 201-451 Range on HMM: 1-280/280 Sequence Identity: 27% (79 aa) FEEIKEIGRGVSAHVYYGKHKRTGEYVAIKKFTFQKLNSAKFQSDQREVAVLATA--QHPALLRLIG-ATDS-------WPFCIITEWMDGGSLYKAIHT . .|..|.| || |. | . ||.|. . . || .. .|| ..||.| .|.. | .|..| |..|.| . .. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK PGH-MNATLRTIAAFDIARGMQFLHSRKIVHRDLKSLNVLLDSNKKVKICDFGFSRFAEQS------TEMTSN---IGTP-----HWMAPEVLKRGSRYT ... . ...||.||..|||....|||| |.|...|. |||.||| ||. . ... . |. |||||.. . ...| HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT SKVDVYAYGVLLWELLTS-ETPYDG-----FGSQQIISEVLNFDARPHLPE-------QGNMAMRDLITLCWDRDPNTRPNFDDIVKLF .| ||...||..||..| ..|| | |..| | . . .| |. .| .... ||..||. ||.| .|...| TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |