92747.m00163

Species: T.vaginalis
Alias: 92747.m00163, TvagK0418
External Links:
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
92747.m00163.AA Protein None 687 None Fasta, JSON
92747.m00163.kin_dom Protein Kinase Domain None 265 None Fasta, JSON

Protein domain

Protein domains of 92747.m00163.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 92747.m00163.AA AGC 310-574 30 5.5e-152 396.15 In-house 1-395 (395) Show / Hide
Range on Protein: 310-574
Range on HMM: 1-395/395
Sequence Identity: 30% (122 aa)

FEFIKRVSRGAFARVFLAKKK------STGDIYAIKVQSKSN---ILNKNQGKRILAE------------KDILLHFQ----------NPYIIN-FYYSI
|||.| ...|.| .|.|..||      .||..||.|| .|.    |..||. .....|            ..|| . .          .|.|..  .|| 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

LGTHN--FYIVMEYLP--------GGDLYSLLHEV-Y----SIDEESAKFYAYQ-------IAKALEYLHK-CGIIHRD-LKPDNILVDANGNLKLTDFG
    .   |.||||.|        ||.. ..||        . ||| |.||| .       |. ||||||.  |||||| |||.||| |..|..||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSYLGVVDR--------------------------------RINSDE----------NIVQSDSLVG--TPNYVAPEIILGQKHSFPVDYWS--LGCVVY
|.  |. |.                                .....           . ..  ...|  ||.|.||||.    .....|.||  |||. |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELLMGEPPFTADT----------EKELQNNIILGKFEHLDD---------------EFSPECQDFISRLLTVDPSKRLGAN-------GAEEILNHPWL
|.| | |||..|.          ..|. ..|. |.... ..               .||||..|.|..||..||.||||..       ||||| |||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase 92747.m00163.AA MAST 310-574 38 2.8e-115 373.18 In-house 1-334 (334) Show / Hide
Range on Protein: 310-574
Range on HMM: 1-334/334
Sequence Identity: 38% (130 aa)

FEFIKRVSRGAFARVFLAKKKSTGDIYAIKVQSKSNILNKNQGKRILAEKDILLHFQNPYIINFYYSILGTHNFYIVMEYLPGGDLYSLLHEVYSIDEES
||||| .|.||. .|.|.|.|.|.|..|.||  ||. .|||. .   .|..||   |||.. ...||   . . ..||||. |||. |||| . . ||. 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

AKFYAYQIAKALEYLHKCGIIHRDLKPDNILVDANGNLKLTDFGLSYLGVVDRRINSDEN-----------------------IV---------------
||.|  ... .|||||..||.||||||||.| |.||  ||||||||  | .|.  . .|.                       ..               
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

-------------------QSDSLVGTPNYVAPEIILGQK-HSFPVDYWSLGCVVYELLMGEPPFTADTEKELQNNIILGK---FEHL-------DDEFS
                   | ....||| | |||.||||  |. |||.||.| ..||.| | |||  ||  |. .||.  .    |         |...|
QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS

PECQDFISRLLTVDPSKRLGAN-GAEEILNHPWL
|| || |..||..||.|||||| ||.|. .|| .
PEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF

Kinase 92747.m00163.AA S_TKc 310-574 34 3.3e-107 363.39 SMART 1-231 (231) Show / Hide
Range on Protein: 310-574
Range on HMM: 1-231/231
Sequence Identity: 34% (95 aa)

FEFIKRVSRGAFARVFLAKKKSTGDIYAIKVQSKSNILNKNQGKRILAEKDILLHFQNPYIINFYYSILGTHNFYIVMEYLPG--GDLYSLLHEVYS---
.|... . .|||..|.....|.|| |.|||. .          ..|. | .|| . . |.|...|...   ...|.||||..|  |||......  .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---IDEESAKFYAYQIAKALEYLHKCGIIHRDLKPDNILVDANGNLKLTDFGLSYLGVVDRRINSDENIVQSDSLVGTPNYVAPEIILGQKHSF-PVDYW
   ..|  |.||.|||..||||.|. |||||||||.|||.|   ..|..||||. .                ....|||.|.|||..   .... ..| |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGTPWYMAPEVL---GYGKCKCDWW

SLGCVVYELLMGEPPFTADTEKELQNNIILGKFEHLDDEFSPECQDFISRLLTVDPSKRLGANGAEE----ILNHPWL
|.||..||.| |.|||   ..... ..|            |||. |||...|..||.||..|  | .    | .|||.
SCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 92747.m00163.AA Akt 310-574 41 4.1e-103 330.47 In-house 1-264 (264) Show / Hide
Range on Protein: 310-574
Range on HMM: 1-264/264
Sequence Identity: 41% (114 aa)

FEFIKRVSRGAFARVFLAKKKSTGDIY-AIKVQSKSNILNKNQGKRILAEKDILLHFQNPYIINFYYSILGTHNFYIVMEYLPGGDLYSLLHEVYSIDEE
|.|.|   .|.|..|||.|||.|...| |.|| .|. |..||| . ...|. || | ..|.|.| .||    .. |.||.| .||.|...|.    ..|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

SAKFYAYQIAKALEYLHKCGIIHRD-LKPDNILVDANGNLKLTDFGLSYLG-VVDRRINSDENIVQSDSLVGTPNYVAPEIILGQKHSFPVDYWS-LGCV
 |.||. .|  |.|.||...|| || ||| |||.|..|...||||||.  . . |  .         ... ||| | ||||..|. |. .|| |. ||||
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKT--------KTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCV

VYELLMGEPPFTADTEKELQNNIILGKFEHLD-DEFSPECQDFISRLLTVDPSKRLG--ANGAEEILNHPWL
 ||.. | ||| ..  ...  .|  .. .  | | .||||.|.||.||. ||.||||   |.|.|| .|||.
MYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF

Kinase 92747.m00163.AA SGK 310-574 35 8.7e-95 293.14 In-house 1-283 (283) Show / Hide
Range on Protein: 310-574
Range on HMM: 1-283/283
Sequence Identity: 35% (104 aa)

FEFIKRVSRGAFARVFLAKKKST------------------GDIYAIKVQSKSNIL-------NKNQGKRILAEK-DILLHFQNPYIINFYYSILGTHNF
|.|.| .  | | .|...|.|..                  ...||.||..|  |.       .|.. | |.||. .||  .  | |.|  |.   .   
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YIVMEYLPGGDLYSLLHEVYSIDEESAKFYAYQIAKALEYLHKCGIIHRDLKPDNILVDANGNLKLTDFGLSYLGVVDRRINSDENIVQSDSLVGTPNYV
| ||.|. ||.. . |    .  |  |.||| .|. ||||||.  ||.|||||.||| |. |...||||||. .|. .    .        .  ||| | 
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTF--------TFCGTPEYL

APEIILGQKHSFPVDYWSLGCVVYELLMGEPPFTADTEKELQNNIILGKFEHLDDEFSPECQDFISRLLTVDPSKRLGAN-GAEEILNHPWL
|||....| |.  || |.|||| ||...| |||     .... ||| ..   .   .|... | |  ||. ||.||||.. ...|| |||. 
APEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQ-IPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF

Kinase 92747.m00163.AA AktR 310-574 37 1e-93 317.62 In-house 1-268 (268) Show / Hide
Range on Protein: 310-574
Range on HMM: 1-268/268
Sequence Identity: 37% (103 aa)

FEFIKRVSRGAFARVFLAKKK-STGDIYAIKVQSKSNILNKNQGKRILAEKDILL-HFQNPYIINFYYSILGTHNFYIVMEYLPGGDLYSLLHEVYSIDE
|...|   .|||..|.|..||  ....||.|. .|..| ..|| .... |..|.  . ..| |....|..    . ...||| |||.|.. |     ..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

ESAKFYAYQIAKALEYLHKC-GIIHRDLKPDNILVDANGNLKLTDFGLSY-LGVVDRRINSDENIVQSDSLVGTPNYVAPEIILG-QKHSFPVDYWSLGC
| |.||. ||  ||||||.   || |||||.||| | .|..|.||||||  ... ...          .|..||| |.|||.|.  . | ..||.|..|.
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDE-------KAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGI

VVYELLMGEPPFTA-DTEKELQNNIILG-KFEHLDDEFSPECQDFIS-RLLTVDPSKRLG--ANGAEEILNHPWL
..||...| |||.. ... ..|. .|   ..     .||..|.|.|  .||  .| ||||  .||.||| .||| 
FIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF

Kinase 92747.m00163.AA Pkinase 310-574 31 2.3e-93 321.29 Pfam 1-293 (293) Show / Hide
Range on Protein: 310-574
Range on HMM: 1-293/293
Sequence Identity: 31% (97 aa)

FEFIKRVSRGAFARVFLAKKKSTGDIYAIKVQSKSNILNKNQGKRIL-AEKDILLHFQNPYIINFYYSILGTHNFYIVMEYLPGG----DLYSLLH--EV
....... .|.|..|.....|.||.|.|.|. .|...  . .  ... .|  |..... |.|. .|..     . |.||||..||    ||.....  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

YSI--DEESAKFYAYQIAKALEYLHKCGIIHRDLKPDNILVDANGNL----KLTDFGLSYLGVVDRRINSDENIVQSDSLVGTPNYVAPEIIL-GQKHSF
 ..  .|. .|||.|||...|||.|..|||||||||.|||.| ||..    |..||||. .           | .  ....|||.|.|||.|. ||... 
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

PVDYWSLGCVVYELLMGEPPFTAD------TEKELQNNIILGKFEHLDDEFS--------------------PECQDFISRLLTVDPSKRLGANGAEEIL
.|| ||.||..||.| |.|||  .      ..... ..|  ....   .. .                    .||.|||...|..||.||..   ||.||
KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQIL

NHPWL
.|||.
QHPWF

Kinase 92747.m00163.AA RSK 314-574 35 2.2e-92 313.23 In-house 1-278 (278) Show / Hide
Range on Protein: 314-574
Range on HMM: 1-278/278
Sequence Identity: 35% (102 aa)

KRVS-RGAFARVFLAKKK---STGDIYAIKVQSKSNILNKNQ-GKRILAEKDILLHFQ-NPYIINFYYSILGTHNFYIVMEYLPGGDLYSLLHEVYS---
 .|  .|..  ||| .|.    || ||| || .|. | ...   .. ..| .||.. |  | |.. .|.      .|..|||..||.|.  | .  .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

IDEESAKFYAYQIAKALEYLHKCGIIHRDLKPDNILVDA---NGNLKLTDFGLSYLGVVD--RRINSDENIVQSDSLVGTPNYVAPEIIL---GQK-HSF
..|. |.||...|..|.|.||. |||||||||.||| |    .| .||||||.. ... |   . ..          ..| .|.|||..    .|. |. 
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMT---------FCYTIEYMAPEMLKRANQQGGHDK

PVDYWSLGCVVYELLMGEPPFTA---DTEKELQNNIILGK--FEHL-DDEFSPECQDFISRLLTVDPSKRLG--ANGAEEILNHPWL
 .|.||||.. ||.|.| |||..   .. ||. ..|  ||  ...  ... |.|..|.|...|..||.||||   ..||||..|||.
ACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase 92747.m00163.AA Ciliate-E2 310-574 27 5.7e-92 311.85 In-house 1-365 (365) Show / Hide
Range on Protein: 310-574
Range on HMM: 1-365/365
Sequence Identity: 27% (103 aa)

FEFIKRVSRGAFARVFLAKKKSTGD-----------------------IYAIKVQSKSNILNKNQGKRIL----------AEKDILLHFQNPYIINFYYS
..|||   .|.|. |...|.....                        |||.|...|..| ...| ..|.           || || . ..|.||..|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IL--GTHNFYIVMEYLPGGDLYSLLHEV-----------YSIDEESAKFYAYQIAK---------------ALEYLHKCG-IIHRDLKPDNILVDANGNL
     ..|.|.||||. ||||.... .             ...|. .|.. .||..               ||||||. . |||||.||.|||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGLSYLGVVDRRINSDENIVQS------------------------DSLVGTPNYVAPEIILGQK---------HSFPVDYWSLGCVVYELLMGEP
|..|||||     |.  ... .  .                         ....|||.|.||||. |.|         ... .|.||||.. ||.|.|.|
KIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFTADTEKELQNNIILGKFEHL-----------------DDEFSPECQDFISR----LLTVDPSKRLGANGAEEILNHPWL
||        |..|. .|..                    .. |.||.|.|..    .| .||.||..  |.|.||||||.
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF

Kinase 92747.m00163.AA Ciliate-E2-Unclassified 310-574 28 4.6e-91 308.84 In-house 1-352 (352) Show / Hide
Range on Protein: 310-574
Range on HMM: 1-352/352
Sequence Identity: 28% (102 aa)

FEFIKRVSRGAFARVFLAKKKSTGDIYAIKVQSKSNILNKNQGKR---------ILAEKD-------------ILLHFQNPYIINFYYSILGTHNFYIVM
...||   .|.|. |.....|... .||.|  .|..| ...| ..         .. .|              |||....|.|....|    . |.||||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYLPGG-----------------DLYSLLHEVYSIDEESAK-----FYAYQIAKALEYLHKCG-IIHRDLKPDNILVDANG---NLKLTDFGLSYLGVVD
||..||                 ||.  ...   ..|. ||     ||..|| ..|||||. . |||||.||.|||.| ||   ..|..|||.|.    .
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

RRINSDEN-----IVQSDSL---VGTPNYV----APEIILGQKHS----FPVDYWSLGCVVYELLMGEPPFTADTEKE----------------LQNNII
. .  ...     | ... .   .|||||     |||.. ||...    . .|.||||.. ||.|.|..|| . ....                |..||.
NNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

LGKFEHLD-------DEFSPECQDFIS----RLLTVDPSKRLGANGAEEILNHPWL
 ....          .  |||..|||.    ..| ..|.||.   ..|.||||||.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI---TFEQILNHPWF

Kinase 92747.m00163.AA MAST 310-468 45 2.7e-71 216.84 In-house 1-162 (337) Show / Hide
Range on Protein: 310-468
Range on HMM: 1-162/337
Sequence Identity: 45% (73 aa)

FEFIKRVSRGAFARVFLAKKKSTGDIYAIKVQSKSNILNKNQGKRILAEKDILLHFQNPYIINFYYSILG--THNFYIVMEYLPGGDLYSLLHEVY-SID
||||| .|.||. .|.|.|.|.|.|..|.||  ..... ||| . . .|..||   |||.. ...||     .   ..||||. |||  |||. .  . .
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EESAKFYAYQIAKALEYLHKCGIIHRDLKPDNILVDANGNLKLTDFGLSYLGVVDRRINSDE
|. ||.|  ..  .|||||..||.||||||||.| |.|| .||||||||  | .|.  | .|
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYE

Kinase 92747.m00163.AA NDR 310-455 45 4.1e-64 196.37 In-house 1-151 (350) Show / Hide
Range on Protein: 310-455
Range on HMM: 1-151/350
Sequence Identity: 45% (69 aa)

FEFIKRVSRGAFARVFLAKKKSTGDIYAIKVQSKSNILNKNQGKRILAEKDILLHFQ--NPYIINFYYSILGTHNFYIVMEYLPGGDLYS---LLHEVYS
||.|| ...||| .|.|..||.||.|||.|.  || ...||| . ..||.||.   .  ||..   |||     ..| ||||.||||. .   || .   
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

IDEESAKFYAYQIAKALEYLHKCGIIHRDLKPDNILVDANGNLKLTDFGLS
 .|. |.||   .. |.|..|| |.||||.||||.|.|. | .|||||||.
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLC

Kinase 92747.m00163.AA MAST 469-574 47 1.8e-46 139.57 In-house 221-337 (337) Show / Hide
Range on Protein: 469-574
Range on HMM: 221-337/337
Sequence Identity: 47% (55 aa)

NIVQSDSLVGTPNYVAPEIILGQK-HSFPVDYWSLGCVVYELLMGEPPFTADTEKE-LQNNIIL--GKFEHLDD-------EFSPECQDFISRLLTVDPS
|| | .. .||| | |||.||||  .. |||.||.| ..||.| |.||| .||  | . .|||    . |  ..       ..||| || |..||...|.
NIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPK

KRLGANGAEEILNHPWL
||||||||.|| .||  
KRLGANGADEIKQHPFF

Kinase 92747.m00163.AA NDR 475-574 39 1.3e-45 138.28 In-house 240-350 (350) Show / Hide
Range on Protein: 475-574
Range on HMM: 240-350/350
Sequence Identity: 39% (44 aa)

SLVGTPNYVAPEIILGQK-HSFPVDYWSLGCVVYELLMGEPPFTADTEKELQNNIILGKFEHL-----DDE----FSPECQDFISRLLTVDPSKRLGANG
|.||||.| |||...... ... .|.|||||. ||.|.| ||| .|| .| . .|.  | . .     ...    .|||..| | ||...||..|||..|
STVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWK-QTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHG

--AEEILNHPWL
  ..|| .||. 
KGVDEIKSHPFF

Kinase 92747.m00163.AA Pkinase_Tyr 310-516 29 9.1e-25 84.51 Pfam 1-216 (270) Show / Hide
Range on Protein: 310-516
Range on HMM: 1-216/270
Sequence Identity: 29% (65 aa)

FEFIKRVSRGAFARVFLAKKK----STGDIYAIKVQSKSNILNKNQ--GKRILAEKDILLHF-QNPYIINFYYSIL-GTHN--FYIVMEYLPGGDLYSLL
 .|.|   .||| .|.... |    .|.   |.|.  |     . |   .  ..|  |. .. ..| |...|  ..        |||||| |.|||.. |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

HE----VYSIDEESAKFYAYQIAKALEYLHKCGIIHRDLKPDNILVDANGNLKLTDFGLSYLGVVDRRINSDENI-VQSDSLVGTPNYVAPEIILGQKHS
..      ... .    ...||||..|||.  ..|||||   |.||. |.  | .||||.      | | .|..  .....        ||| |   | .
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA------RDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFT

FPVDYWSLGCVVYELLM-GEPP-F
   | || | . .|..  || | .
TKSDVWSFGVLMWEIFTYGEQPTY

Kinase 92747.m00163.AA TyrKc 310-569 22 1.4e-17 61.67 SMART 1-280 (280) Show / Hide
Range on Protein: 310-569
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

FEFIKRVSRGAFARVFLAKKKSTGDIYAIKVQSKSNILNKNQGKRILAEKDILLHF--QNPYIINFYYSILGT-------HNFYIVMEYLPGGDLYSLLH
 ...|   .||| .|.... |      |.|.  ..        . .. |  |. ..  ..| |...|  ..         .  .||||| |.||| . |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

EVYS-IDEESAKFYAYQIAKALEYLHKCGIIHRDLKPDNILVDANGNLKLTDFGLSYLGVVDRRINSD-------ENIVQ----SDSLVGTPNYVAPEII
.    .  .    ...|||.  ||||. ..|||||   |.||..|.  | .|||||      | | .|       . ...    .   .      ||| |
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLS------RDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

LGQKHSFPVDYWSLGCVVYELL-MGEPPFTA-----DTEKELQNNIILGKFEHLDDE--------FSPECQDFISRLLTVDPSKRLGANGAEEIL
   | ..  | || | . .|..  |..|         . .|. ...  |.     ..         ..|  . ...    ||..|   .   |..
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF