Gene 86797.m00083 (T.vaginalis)

86797.m00083

Species: T.vaginalis
Alias: 86797.m00083, TvagK0193
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
86797.m00083.AA Protein None 224 None Fasta, JSON
86797.m00083.kin_dom Protein Kinase Domain None 188 None Fasta, JSON

Protein domain

Protein domains of 86797.m00083.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase 86797.m00083.AA Pkinase 14-199 29 8.9e-54 189.77 Pfam 1-208 (293) Show / Hide 
Range on Protein: 14-199
Range on HMM: 1-208/293
Sequence Identity: 29% (62 aa)

FEFRDIIGAGGSGVVYRIYDPAYHCEFALKSIFRSKFNQ---------SEIDIMNKLEDSNLVRLYNYEFYEDSVYLLMEYCPT-----SLHDILR--QK
...  .||.|..|.||. ..  . ...|.| | ... .          ||| ||..|   | |||| .  ..|..|. ||||.      .|.|...  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KRL--SFEQLRKYSIGILKAVKACHSNKIAHKDIKPANFLIDQYDRI----RLCDFGLSSV--QLDSALDKNFVGSVPFMAPEILMRKPHDAFKTDIWAV
...  | .....|   ||.... |||..| | |.||.|.|||. . |    ..|||||. .     .   . |.|. ..||||...  ...  | |.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVTFFIMATG
|.....|..|
GCILYEMLCG
S_TKc 86797.m00083.AA S_TKc 14-220 25 9.5e-49 169.19 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-220
Range on HMM: 1-231/231
Sequence Identity: 25% (64 aa)

FEFRDIIGAGGSGVVYRIYDPAYHCEFALKSIFRSKFNQSEIDIMNKLEDSNLVRLYNYEFYEDSVYLLMEYCPT---SLHDILRQKKR------LSFEQ
.|. ..|| |. |.||. ..   . ..|.| |   .  ..||.|. |    |.|.|| .    |..|. ||||..   .|.|......|      ..  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

LRKYSIGILKAVKACHSNKIAHKDIKPANFLIDQYDRIRLCDFGLSSVQLDSALDKNFVGSVPFMAPEILMRKPHDAFKTDIWAVGVTFFIMAT------
 |.|   |..|.. |||..| | |.||.| |.|.  .| .|||||. .       . |.|.  .||||.|   ... .| |.|..|.....|..      
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP

-------------------GMLQW--QERIALLYVIICY-----HLLL
                   ..||.  ..|.    .         |  .
QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 86797.m00083.AA CAMK 19-199 19 6.6e-46 145.47 In-house 1-330 (425) Show / Hide 
Range on Protein: 19-199
Range on HMM: 1-330/425
Sequence Identity: 19% (66 aa)

IIGAGGSGVVYRIYDPAYH------------CEFALKSIFRSKFN---------------------------------QSEIDIMNK-------LEDSNL
..| |. |.|.. ..                 ..| | | ..|                                   ..||.||.|       |   |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLYNYEFYED---------------------SVYLLM---EYCPT-----SLHDILRQK---------------KRLSFEQLRKYSIGILKAVKACHSN
..||  |.|||                      .|. |   |||.       | | ....               .|.. .. |.|   |. ||. |||.
IKLY--EVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

KIAHKDIKPANFLIDQYD-----------------RIRLCDFGLSSVQLDSALDKN------------------------FVGSVPFMA-PEILMR----
.|.| |.|| | |.|. .                  | ..|||.. .  ..  ...                        |.|. ..|| ||.| .    
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------KPHDAFKTDIWAVGVTFFIMATG
         || . .|.|.|..||  .|| .|
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCG
Kinase 86797.m00083.AA CAMKL 14-199 29 3.1e-45 142.2 In-house 1-232 (297) Show / Hide 
Range on Protein: 14-199
Range on HMM: 1-232/297
Sequence Identity: 29% (68 aa)

FEFRDIIGAGGSGVVYRIYDPAY-HCEFALKSIFRSKFN--------------------QSEIDIMNKLE---DSNLVRLYNYEFYEDS------VYLLM
... . .| |. |.|    .  .  .. | | | ..| .                    . || || .|      | ..||     ..       .|| |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCPTS---LHDILRQK----KRLSFEQLRKYSIGILKAVKACHSNKIAHKDIKPANFLIDQYD--RIRLCDFGLSSVQLD-----SALDKNFVGSVPFM
|||.     |.| ....    .|.. .. |.|   |. ||. |||..|.| |||| | |.|. .   | ..|||.|  . .       . | | || |.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEILMR--KPHDAFKTDIWAVGVTFFIMATG
||||. .  ||.|..|.|||. ||. . | .|
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCG
Kinase 86797.m00083.AA STE 14-203 25 1.2e-40 141.22 In-house 1-268 (359) Show / Hide 
Range on Protein: 14-203
Range on HMM: 1-268/359
Sequence Identity: 25% (71 aa)

FEFRDIIGAGGSGVVYRIYDPAYHCE-------------------FALKSI----------------------FRSKFNQSEIDIMNKLE--DSNLVRLY
.|. ..|| |..|.||.    |.. .                   .| | .                         .  . ||.||.|.     | |. |
WEGIEKIGKGAFGTVYK----AMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYY

NYEFYE-------DSVYLLMEYCP-TSLHDILRQK--------------KRLSFEQLRKYSIGILKA-VKACHSNKIAHKDIKPANFLIDQYDRIRLCDF
 ..|.|       |.... |||..  || ||...|              .|.. .|....   |||.  .  ||..| | |||||| |.     . ||||
GCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDF

GLSS-VQLDSA----------------LDKNFVGSVPFMAPEILMR------KPHDAFKTDIWAVGVTFFIMATGMLQW
|... .. ..|                  . |||.  .||||....      |..| .| ||| .| |   ||||   |
GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPW
Kinase 86797.m00083.AA Ciliate-E2-Unclassified 14-199 20 2e-40 137.96 In-house 1-266 (352) Show / Hide 
Range on Protein: 14-199
Range on HMM: 1-266/352
Sequence Identity: 20% (56 aa)

FEFRDIIGAGGSGVVYRIYD----PAYHCEFALKSIFRS--KFNQSEIDIMNKLEDSNL-------------------------VRLYNYEFYEDSVYLL
...  .|| || |.||. ..     .|. . . |.. ..  . .... .|||...  |                          |... ..  .. .|. 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYCP-TSLHDILRQK-----------------KRLSFEQLR-----KYSIGILKAVKACHSNK-IAHKDIKPANFLIDQYD---RIRLCDFGLSS----
||||.  .|.......                 |... .| .     .|   ||.. . .|... | | |||| | |.|.     .|...|||.|.    
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

------------VQLDSALDKNFVGSVPFM----APEILMRKPHDA---FKTDIWAVGVTFFIMATG
             .... . . |.|.  .|    |||.|... .|    .| |||..|| .. | .|
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFG
Kinase 86797.m00083.AA Ciliate-E2 14-199 20 1.9e-37 126.13 In-house 1-292 (365) Show / Hide 
Range on Protein: 14-199
Range on HMM: 1-292/365
Sequence Identity: 20% (61 aa)

FEFRDIIGAGGSGVVYRIYDPAYHCEFALKSIFRSK-------------------FNQSEIDIMNKLEDSN-----------------------LVRLYN
..|  .|| |. |.||.  .    ..||.| |   |                   .....| .... .. .                       ....| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

YEFY---EDSVYLLMEYCPT-SLHDILRQK-----------KRLSFEQLRKYSIGILK---------------AVKACHSNK-IAHKDIKPANFLIDQYD
. |.   ....|| ||||   .| |.....           |... .. ....  ||.               |.. .||.. | | |||| | |.    
C-FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

RIRLCDFGLSSVQLDS------------ALDKN---------------------FVGSVPFMAPEILMRKPHDA--------FKTDIWAVGVTFFIMATG
 | ..|||||  . |.             .. .                     ..|. ..||||||..|. |         .| |||..||....| .|
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG
Kinase 86797.m00083.AA ULK 14-199 25 7.3e-37 126.24 In-house 1-252 (329) Show / Hide 
Range on Protein: 14-199
Range on HMM: 1-252/329
Sequence Identity: 25% (63 aa)

FEFRDIIGAGGSGVVYRIYDPAYH----CEFALKSIFRSKFNQ---------------SEIDIMNKLE----DSN----LVRLYNYEFYEDS--VYLLME
.. ....| |  |.||. ..   .      .| | | ..|.||               .||.|| ||       |     |.|| .    ..  .|. ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPT-SLHDILRQKKRLSFEQ----------LRKYSIGILKAVKACHSNKIAHKDIKPANFLIDQYD------------RIRLCDFGLSSV-QLD---SA
||.   | ... ..|.|. ..           ... . || . |. |...| | ||||.| ||.  .            .. ..|||.. . . |    .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LDKNFV------GSVPFMAPEILM----RKPHDAFKTDIWAVGVTFFIMATG
. . .|      |.  .|||.||.    .||.. .|.||| .|. |. | .|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYG
Kinase 86797.m00083.AA ULK 14-199 24 3.4e-36 125.93 In-house 1-248 (324) Show / Hide 
Range on Protein: 14-199
Range on HMM: 1-248/324
Sequence Identity: 24% (60 aa)

FEFRDIIGAGGSG-VVYRIYDPAYH---CEFALKSIFRSKFNQ---------------SEIDIMNKLE---DSN--LVRLYNYEFYEDS--VYLLMEYCP
.. ....| |  | .||. ..   .     .| | | ..|.|.               .|| || ||      |   |.|| .    ..  .|. ||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

T-SLHDILRQKKRLSFEQ----------LRKYSIGILKAVKACHSNKIAHKDIKPANFLIDQYD------------RIRLCDFGLSSV-Q---LDSALDK
   | ... ..|.|.. .           ... . |. . |. |...| | ||||.| ||   .            .. ..|||.. . .   ..  . .
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

NFV------GSVPFMAPEILM----RKPHDAFKTDIWAVGVTFFIMATG
 .|      |.  .|||.||.    .||.. .|.||| .|. |. | .|
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYG
Kinase 86797.m00083.AA CMGC 14-194 18 8e-34 107.83 In-house 1-326 (513) Show / Hide 
Range on Protein: 14-194
Range on HMM: 1-326/513
Sequence Identity: 18% (60 aa)

FEFRDIIGAGGSGVVYRIYDPA--------------YHCEFALKSIFRSKFNQ-----------------SEIDIMNKLE-----------------DSN
.|  . || |  ||||. .|                .  . |.| |.. . ..                  || |. .|                  . |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

LVRLYNYEFYED-----------------SVYLLMEYCPTSLHDILRQ----------------------------KKRLSFEQLRKYSIGILKAVK--A
.|.||..  ...                 ..|| .||....|......                            .| ..  . | |.  ||...|   
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

CHSNK--IAHKDIKPANFLID--------------------QYDRIRLCDFGLSS-VQLD---------------------SALDKNFVGSVPFMAPEIL
|||..  | | |.||.| ||.                    . .|...|||||.  .                        .    . | .    |||||
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

MRK---------PHDAFKTDIWAVGVTFF
..           |   . |.|.||  |.
LGWKHYTNHNYSMHYTTPIDMWSVGCIFA
Kinase 86797.m00083.AA MARK 14-199 33 2.4e-32 103.15 In-house 1-202 (262) Show / Hide 
Range on Protein: 14-199
Range on HMM: 1-202/262
Sequence Identity: 33% (68 aa)

FEFRDIIGAGGSGVVYRIYDPAYHCEFALKSIFRSKFNQ--------SEIDIMNKLEDSNLVRLYNYEF--YEDS-VYLLMEYCP-TSLHDILRQK--KR
...   || |. ..|.   .  .. ..|.| . . | |         .||.|| ||.  | ..|. .     |   .|| |||.. ..|.| ....   |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSFEQLRKYSIGILKAVKACHSNKIAHKDIKPANFLIDQYD--RIRLCDFGLSSVQLDSALDKNFVGSVPFMAPEILMRKPHDAFKTDIWAVGVTFFIMA
|. |  |..   |. ||. |||. |.| |||| | |||.     | ..|||.|       . . | |. |.|||||. .|| |..|.|||. ||  ..| 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TG
.|
CG
Kinase 86797.m00083.AA CAMKK 52-201 21 1.8e-29 90.33 In-house 75-324 (396) Show / Hide 
Range on Protein: 52-201
Range on HMM: 75-324/396
Sequence Identity: 21% (53 aa)

QSEIDIMNKLEDSNLVRLYNY--EFYEDSVYLL-MEYC--------PTSLHDILRQ------------------KKRLSFEQ------------------
..|| || |..  | |.|| .    ..|..|.  ||||        |.   |. ..                  .. .|..|                  
YQEIAIMKKCNHPNIVKLYEVIDDPQNDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIH

---LRKYSIGILKAVKACH-SNK-------------------IAHKDIKPANFLIDQYD---RIRLCDFGLSSVQLDSALDK--N-----------FVGS
   ..||  ...|... .| ..|                   | |.|||| | |||. .   .. ..|||  |.....  ..  |            .| 
EDYAWKYFRDCIKGLEYLHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGV-SHIFEGQDQTLSNCESCFQRELNKTAGT

VPFMAPEILMR-KPH--------------DAFKTDIWAVGVTFFIMATGML
  ||||| . . . .              . .. ||||.|||.... .|..
PAFMAPELCSKENQKENYNGYKYRFRFIYCGKAADIWALGVTLYCFVFGKC
Kinase 86797.m00083.AA TyrKc 14-224 19 2.2e-09 -71.0 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-224
Range on HMM: 1-280/280
Sequence Identity: 19% (55 aa)

FEFRDIIGAGGSGVVYR-IYDPAYHCEFALKSIFRSKFNQ---SEIDIMNKL--EDSNLVRLYNYEFYE-------DSVYLLMEYCPT-SLHDILRQKKR
 .. ...| |  |.||. ...     . | |..  ..  .   .|. || ||  .  |.|||| .   .       . ....|||.|  .|.| || ...
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-LSFEQLRKYSIGILKAVKACHSNKIAHKDIKPANFLIDQYDRIRLCDFGLSSVQLDS--------ALDKNF--VGS--VPF--MAPEILMRKPHDA---
 |. ..| .... | .     ||... | |.   | |..   ... .|||||    |           .|     |   .|   |||| .     .    
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----NYGKFT

FKTDIWAVGVTFF-IMATGMLQWQE-------------RIALLYVIICYHL--------------------------------LLVSNI
.|.|.|. ||. . |.  |.  . .             ..   |   . .                                  ... .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF