Gene 90371.m00099 (T.vaginalis)

90371.m00099

Species: T.vaginalis
Alias: 90371.m00099, TvagK0407
External Links:
Annotation:

Classification

Group: Other
Family: Aur

Sequence

Name Sequence Type Origin Length Description Download
90371.m00099.AA Protein None 297 None Fasta, JSON
90371.m00099.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 90371.m00099.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90371.m00099.AA Aur 38-288 60 5.70000000001e-218 582.18 In-house 1-257 (257) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-257/257
Sequence Identity: 60% (155 aa)

FEIGRPLGTGKFGRVYLAREAKSKFIVGIKVLNKAQLQKASIEHQLRREIEIQSHLRHPNIIRLYGYFYDATRIYLIIEYAARGELFSILRDA--GRFDE
||||.||| ||||.|||||. |..||. .||..| |..|  .||||||||.|||||.||||...||||.|..|||||.||| .|||.. |. .  .||||
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

HTAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVG-LNGELKIADFGWSVHAP-TSRRTTLCGTLDYLPPEMIEGYDHDNSVDIWSLGVLLYEFLVGEPP
 .|| |. |.|.|.||||||.||||||||||||.. .||..||.|||||||.|  .||.|.||||||.||||.|| .|| .||||.||||.||...| ||
QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPP

FET-DSQRNTCRRII-NVDIRFPSFVTPLARDLILRFLQKDPAKRMPLSQVRSHPWI
||  ...  | .||. .|||.|||.... |.||| . ||.|| .||.| |. .||||
FESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase 90371.m00099.AA AGC 38-288 24 2.3e-118 307.18 In-house 1-395 (395) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-395/395
Sequence Identity: 24% (99 aa)

FEIGRPLGTGKFGRVYLAREA------KSKFIVGIKVLNKAQ---------LQKASIEHQ------LRREIEIQSHLR----------HPNIIR-LYGYF
||. ...|.| ||.|||.|.        .. .  .|||.|.          .... .||       ...| .| ....          ||.|.. |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

YDATR--IYLIIEYAA---------RG-ELFSILR---DAGRFDEHTAAEYIVQ-------MCDAIDYCHS-KHIIHRD-IKPENILVGLNGELKIADFG
 | ..  .|.. ||.           | |||..|.   . ||||| .|  |. .       .. |..| || ..||||| .||||||   .| .|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

WSVHAPTS----------------------------------------------------RRTTLCG--TLDYLPPEMIEGYDHDNSVDIWS--LGVLLY
 .   ...                                                    | .|.||  | .|..||..    .. ..|.||  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFLVGEPPFETDS----------QRNTCRRII------NVDIRFP----------SFVTPLARDLILRFLQKDPAKRMP----------LSQVRSHPWI
|.|.| |||  |.          .  .  .|.      | ...||          ....| |.||| ..|.|||.||             .....||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 90371.m00099.AA S_TKc 38-288 36 2.2e-103 350.67 SMART 1-231 (231) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-231/231
Sequence Identity: 36% (98 aa)

FEIGRPLGTGKFGRVYLAREAKSKFIVGIKVLNKAQLQKASIEHQLRREIEIQSHLRHPNIIRLYGYFYDATRIYLIIEYAAR--GELFSILRDAGR---
.||.|..| | ||.||..|. |.. || ||...           ..||||.| .. .||||..||..|.| ...|.. ||.    |.||..... ||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FDEHTAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVGLNGELKIADFGWSVHAPTSRRTTLCGTLDYLPPEMIEGYDHDN-SVDIWSLGVLLYEFL
   |.| .|. |. |.|.|..||||..|||||.||||||.    ..||.||| . .      ||.|||..|..||..    ..  ..|.||.|..|||.|
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

VGEPPFETDSQRNTCRRIINVDIRFPSFVTPLARDLILRFLQKDPAKRMPLSQVRS-------HPWI
.|.|||.   .  . ..|           .| |.|.| . |||||.||.   ..         |||.
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 90371.m00099.AA CAMK 43-288 24 2.5e-99 320.72 In-house 1-425 (425) Show / Hide 
Range on Protein: 43-288
Range on HMM: 1-425/425
Sequence Identity: 24% (102 aa)

PLGTGKFGRVYLAREAKSK------------FIVGIKVLNKAQLQK-------------------------ASIEHQLRREIEIQSH-------LRHPNI
 ||.| || |.|... ...              | ||...| .|..                         .. ....|||||| ..       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLYGYFYDAT-------------------RIYLII---EYAARGEL----FSILRDA---------------GRFDEHTAAEYIVQMCDAIDYCHSKHI
|.|| .. |..                   ..|..    ||.  |||    |. ...                |||.|. |. |. |.|.|..||||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPENILVGLN-----------------GELKIADFGWSVHAPTSR-------------------------RTTLCGTLDYLP-PEMIEGYD----
.|||.||||||.  |                 . .||.||| . . . .                           .| |||. | . ||...|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------HDNSVDIWSLGVLLYEFLVGEPPFETD-------------SQRNTCRRIINVDIRFPSF------------------------VTPLARD
          .. ..|.||.||.||  |.|.|||. |             ........|.. . .||..                        |.. ..|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LILRFLQKDPAKRMPLSQVRSHPWI
|| . ||.|| ||| ..|. .|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 90371.m00099.AA CAMKL 38-288 35 1.9e-95 305.06 In-house 1-297 (297) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-297/297
Sequence Identity: 35% (105 aa)

FEIGRPLGTGKFGRVYLAREAKS-KFIVGIKVLNKAQLQKASIEHQ------------LRREIEIQSHLR---HPNIIRLYGYFYDATR------IYLII
..||. ||.| || | ||.  .  .  | ||...|  ...  . ..            .||||.|...|.   |||||.||  ... .       |||. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAARGE--LFSILRDA----GRFDEHTAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVGLNG--ELKIADFGWS-----V-HAPTSRRTTLCGTLDYL
||.  ||  ||  ..      ||..|| |  |  |...|..||||..|.||||||||||.  ||   .||.||| |     .   |    .| ||.. | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPEMIEG--YDHD-NSVDIWSLGVLLYEFLVGEPPFETDS-------QRNTCRRIINVDIRFPS---FVTPLARDLILRFLQKDPAKRMPLSQVRSHPWI
.||...|   ..|   |||||.||.||  ..|. ||. |.          . ...|...  .|    .|   .|||| . ||..| ||. . |...||| 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 90371.m00099.AA MARK 38-288 37 7.6e-89 290.54 In-house 1-262 (262) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-262/262
Sequence Identity: 37% (98 aa)

FEIGRPLGTGKFGRVYLAREAKSKFIVGIKVLNKAQLQKASIEHQLRREIEIQSHLRHPNIIRLYGYFY--DATR-IYLIIEYAARGELFSILRDA--GR
..... .|.| .. |.||.  ...  | ||...| .|..      ..||||| ..| |||||.|. ..   . .. |||| ||| .|||.. .. .  ||
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FDEHTAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVGLNG--ELKIADFGWSVHAPTSR-RTTLCGTLDYLPPEMIEGYDHD-NSVDIWSLGVLLYEFL
  |  |  .  |.. |. |||||.|.||||||||||.  ||    ||.|||.|.. |. .  .| |||. | .||.... . |   ||||||||.||  .
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

VGEPPFETDS--QRNTCRRIINVDIRFPSFVTPLARDLILRFLQKDPAKRMPLSQVRSHPWI
.|  ||. |.  . .  ..| . . ..|..| . .|.|| |.|. .| .|. .... .|||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 90371.m00099.AA Pkinase 38-288 34 9.5e-89 305.95 Pfam 1-293 (293) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-293/293
Sequence Identity: 34% (103 aa)

FEIGRPLGTGKFGRVYLAREAKSKFIVGIKVLNKAQLQKASIEHQLRR--EIEIQSHLRHPNIIRLYGYFYDATRIYLIIEYAARG----ELFSILR--D
..|||..| | ||.||.... ..  || .|...|   .| . . ..||  ||.|  .|.||||.|||..|.| ..||.. ||.  |    .||....  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

AGRF--DEHTAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVGLNGEL----KIADFGWSV---HAPTSRRTTLCGTLDYLPPEMIE-GYDHDNSVDIWS
 |.|  .|...  |. |.. ...||||. |||||.||||||.  ||..    ||.||| .    . . |  ||.|||..|..|| |  | ... .||.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGVLLYEFLVGEPPFETD------SQRNTCRRIINVDIRFPSFVT---------------------PLARDLILRFLQKDPAKRMPLSQVRSHPWI
.|..|||.| |.|||  .      .|.   .||   ...|... .                     . ..|.| . |.|||.||    |.  |||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 90371.m00099.AA Ciliate-E2 38-288 26 4.5e-81 275.66 In-house 1-365 (365) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-365/365
Sequence Identity: 26% (101 aa)

FEIGRPLGTGKFGRVYLAREAKSK-----------------------FIVGIKVLNKAQLQKASIEHQLRREIE----------IQSHLRHPNIIRLYGY
... . .|.| || ||...  | .                       .|. .|...| |..  . | .. |||.          |...| |||||..| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FY--DATRIYLIIEYAARGELFSILR------------DAGRFDEHTAAEYIVQMCD---------------AIDYCHSKH-IIHRDIKPENILVGLNGE
|.  | . |||. ||.  |.||....            | ..|.|  ..... | ..               |. |.|||. ||||||||||||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

LKIADFGWSVHAPTSRR---------------------------------TTLCGTLDYLPPEMIE---------GYDHDNSVDIWSLGVLLYEFLVGEP
.||.||| |  . ...                                   |.|||. |..||...         . ..| ..|||||||.|||.| |.|
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFETDSQRNTCRRIINV-DIRFPSF------------------VTPLARDLILR----FLQKDPAKRMP-LSQVRSHPWI
||          ..|   .|.||..                  ... . ||| .     ||||| ||.   .|.  |||.
PF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 90371.m00099.AA PLK 38-288 33 3.2e-76 247.71 In-house 1-258 (258) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-258/258
Sequence Identity: 33% (87 aa)

FEIGRPLGTGKFGRVYLAREAKSKFIVGIKVLNKAQLQKASIEHQLRREIEIQSHLRHPNIIRLYGYFYDATRIYLIIEYAARGELFSILRDA-GRFDEH
.|.|..|| | | ..| ... ..| .. |||  |. .|| .    ...||||.. |.|||| ... .| |.  .|.  ||. ...|. ...    |. |.
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

TAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVGLNGELKIADFGWSVHAPT--SRRTTLCGTLDYLPPEMIEGYD--HDNSVDIWSLGVLLYEFLVGEP
 .  |..| . .. | |.. |||||.|. |..   | ..||.||| ..       |. |.|||  |  ||  .|    |.  ||.||||. .| .|.| |
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFETDSQRNTCRRIINVDIRFPSF--VTPLARDLILRFLQKDPAKRMPLSQVRSHPWI
||||..  .| .|| . . .||.   . . |.||| . |...|..|  ..|. .||. 
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase 90371.m00099.AA RSK 41-288 32 4.8e-75 255.62 In-house 1-278 (278) Show / Hide 
Range on Protein: 41-288
Range on HMM: 1-278/278
Sequence Identity: 32% (91 aa)

GRPLGTGKFGRVYLAREA---KSKFIVGIKVLNKAQLQKAS--IEHQLRREIEIQSHLR-HPNIIRLYGYFYDATRIYLIIEYAARGELFSILRDAGR--
 . ||.| .| |.| |.    ... |   |||.|| . ..   ..|  ..|..| .. . ||.|..|.  | . . .||| ||   ||||  |.  ..  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRH-TMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFG

-FDEHTAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVGL---NGELKIADFGWSVHAPTS---RRTTLCGTLDYLPPEMIE----GYDHDNSVDIWSLG
 |.|..|..|. .   |... |...|||||.||||||      .|..|. ||| .  .. .   .  | |.|..|..|||.     .  || ..|.||||
CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VLLYEFLVGEPPFET---DSQRNTCRRIINVD--IRFP--SFVTPLARDLILRFLQKDPAKRMP-----LSQVRSHPWI
||.|| |.| |||     ...  . .|| . .   ..|  ..... |.||| . |..||.||       ......|||.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 90371.m00099.AA PKA 38-288 39 2.3e-74 253.36 In-house 1-263 (263) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-263/263
Sequence Identity: 39% (103 aa)

FEIGRPLGTGKFGRVYLAREAKSKFIVGIKVLNKAQLQKASIEHQLRREIEIQSHLRHPNIIR-LYGYFYDATRIYLIIEYAARGELFSILRDAGRFDEH
||| . |||| ||||.|.|. .|. .. .|.|.|..  .   ..    |. | . ..||.|.. .|. | |.. .|.. ||.. ||.|| ||  |||.. 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

TAAEYIV-QMCDAIDYCHSKHIIHRDIKPENILVGLNGELKIADFGWSVHAPTSRRTTLCGTLDYLPPEMIEGY-DHDNSVDIWSLGVLLYEFLVGEPPF
.|  |.  | . |..| ||..||.|| ||||||   || .||.||| .    . |  ||||| .||.||.| .   |  ||| |.||.| ||.|.| |||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPF

ETD--SQRNTCRRIINVDIRFPSFVTPLA---RDLILRFLQKDPAKRM-PLSQ----VRSHPWI
. .  ..  . ..|.| .|.||..... |   .||| . ||.|. ||   ...    .. |.| 
YDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 90371.m00099.AA Ciliate-E2-Unclassified 38-288 26 3.2e-71 242.94 In-house 1-352 (352) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-352/352
Sequence Identity: 26% (92 aa)

FEIGRPLGTGKFGRVYLAREAKSKFIVGIKVLNKAQLQK-----ASIEHQLRREIEIQSH----------------LRHPNIIRLYGYFYDATR--IYLI
..|.. .|.| || ||.... | |..  .| ..|.| .|      ..   .. ..|....                | ||...... .... ..  ||..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

IEYAARGELFSILRD-----------------AGRFDEHTAA-----EYIVQMCDAIDYCHSKH-IIHRDIKPENILVGLNG---ELKIADFGWSVHA--
 ||.  |.|. ....                   .|.|  |.      |. | .....|.|.|. ||||||||||||.  ||   ..||.||| | .   
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------PTSRRTTLCGTLDYL----PPEMIEGYDHDNS----VDIWSLGVLLYEFLVGEPPFE-TDSQR---------------NTCRRII
               .  . .| |||. |.    .||...|  .|.|    .|||||||.|||.| |..||. ...                 .  . |.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

NVDIRFPS--------FVTPLARDLIL----RFLQKDPAKRMPLSQVRSHPWI
. .| ||.         . | | |.|     . |.|.| ||. ..|.  |||.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 90371.m00099.AA Pkinase_Tyr 38-181 31 2.3e-27 93.27 Pfam 1-156 (270) Show / Hide 
Range on Protein: 38-181
Range on HMM: 1-156/270
Sequence Identity: 31% (50 aa)

FEIGRPLGTGKFGRVYLAREA----KSKFIVGIKVLNKAQLQKAS-IEHQLRREIEIQSHL-RHPNIIRLYGYFY-DATR--IYLIIEYAARGELFSILR
 ..|. || | ||.||...      . |  | .|.| | .  .   .   . ||..| ..| .||||.||||  . .     ||.. ||.. | | . ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

D----AGRFDEHTAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVGLNGELKIADFG
.     .... ..  .. .| ... .| .||..||||.   |.||. |.  ||.|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 90371.m00099.AA TyrKc 38-292 22 1.4e-19 72.28 SMART 1-280 (280) Show / Hide 
Range on Protein: 38-292
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

FEIGRPLGTGKFGRVYLAREAKSKFIVGIKVLNKAQLQKASIEHQLRREIEIQSHL--RHPNIIRLYGYFYDA-------TRIYLIIEYAARGELFSILR
 . |. || | ||.||...       | .|.|..        .  ..||..| ..|  .||||.||||.  .          .... ||.. | | . ||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

DAGR-FDEHTAAEYIVQMCDAIDYCHSKHIIHRDIKPENILVGLNGELKIADFGWSVHAPTS-------RRTTL----CGT----LDYLPPEMIEGYDHD
. .. .   .  .. .| ..  .| |||..||||.   |.||| |.  ||.||| |                .     .|     .  ..|| |  .   
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

NSVDIWSLGVLLYEFL-VGEPPFET-----DSQRNTCRRIINVDIRFPSFV---------TPLARDLILRFLQKDPAKRMPLSQVRSHPWIVQQL
   |.|| ||...| .  |..| .       | .   ... . . . .            ..   .....  . ||..|   |..      ....
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------HECF
Kinase 90371.m00099.AA Pkinase_Tyr 216-226 63 1.925541 2.12 Pfam 196-206 (270) Show / Hide 
Range on Protein: 216-226
Range on HMM: 196-206/270
Sequence Identity: 63% (7 aa)

DIWSLGVLLYE
|.|| |||..|
DVWSFGVLMWE