93331.m00036

Species: T.vaginalis
Alias: TvagK0328, 93331.m00036
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
93331.m00036.AA Protein None 775 None Fasta, JSON
93331.m00036.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 93331.m00036.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93331.m00036.AA TKL 28-275 27 9.2e-81 274.62 In-house 1-364 (364) Show / Hide
Range on Protein: 28-275
Range on HMM: 1-364/364
Sequence Identity: 27% (104 aa)

IGSGGFSEVFDATFIP--------TGQRCAVKKLKFKEIKND-------------------------EFNLYYREIEVLTKLNHPYCLNLIGFSVHRP--
||||||.||. ...          ||.  ||||.| .. ...                         ..    .|| .. .|.||  . ..|..   |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FIIVTELLQRGSLYDALRWKDPEKPLNGSQKTIIAMCIASGMERLHKLN--------IIHRDLKSLNILLDNDKL-------------
            . ||.|. ..|||.. |           .|.  .|. ||.||. ||  |        |||||||| |||.|..               
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PRIIDFGLSREVSESDA-------------------IMTMQIGTPHWMAPELFSSQ----------------PYSFKVDVYSYGMLLWEMLTNSSPFK-
 . | ||||||..|.|                        .|.||| |||||..  |                .|| |.||||.|..|||.||   |.. 
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

GKTA--------AQIMYEVVEKGARPAIP------------NRCPSSLKAMINACWAQDPEQRPTFHQIYKAF
 .           .... |..|| || ||            . || |.|  .  ||..|||.||.| .| | .
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase 93331.m00036.AA TKL-Unique 24-275 31 1.4e-77 264.08 In-house 1-290 (290) Show / Hide
Range on Protein: 24-275
Range on HMM: 1-290/290
Sequence Identity: 31% (93 aa)

IHDTIGSGGFSEVFDATFIPTGQRCAVKKLKF-KEIKNDEFNLYYREIEVLTKLN-HPYCLNLIGFSV----HRP-FIIVTELLQRGSLYDALR------
.  .||.||...|. ...   |   |.|....  .. |..    ..|. .. ||. ||  . ..|...    . | ..||.| ...||||| |       
FWNKIGEGGYGQVYKGKW--RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

-WKDPEKPLNGSQKTIIAMCIASGMERLHKLN--IIHRDLKSLNILLDND-----KLPRIIDFGLSREVS-ESDAIMTMQ--------IGTPHWMAPELF
    ....|| .|.  .| .||.||..|| ..  ||||||||.|.|.||.        .|.|||||.  | ... . ..         .|.. |||||..
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

SS--QPYSFKVDVYSYGMLLWEMLTNSS------PFKGKTAAQIMYEVVE--KGARPAIPNRCPSSLKAMINACWAQDPEQRPTFHQIYKAF
..    || |.||||.|. |||..|.        |..| .  |.   | .  .. || |||.|| ...  |..||..||.|||.| .|..  
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase 93331.m00036.AA MLK 22-275 31 3.2e-71 242.91 In-house 1-291 (291) Show / Hide
Range on Protein: 22-275
Range on HMM: 1-291/291
Sequence Identity: 31% (93 aa)

FEIHDTIGSGGFSEVFDATFIPTGQR-----CAVKKLKF-------KEIKNDEFNLYYREIEVLTKLN-HPYCLNLIGFSVHR-P-FIIVTELLQRGSLY
...|  ||||.| .|. ...   ...      |||. ..       ..   ..|.   |.  .| ..| ||.   . | .    . | ||.| .. ||||
IQFHEWIGSGSFGKVWKGRWR--NKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

DALRWKDPEKP-----------LNGSQKTIIAMCIASGMERLHKLN---IIHRDLKSLNILLDN------DKLPRIIDFGLSREVSESDAIMTMQIGTPH
. |. ....                ...  .|. .|.||. ||..    |||||||| |||.|.      ..  .| |||.||....... |. ..||. 
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYA

WMAPELF---SSQPYSFKVDVYSYGMLLWEMLTNSSPFK-GKTAAQIMYEVVEKGARPAIPNRCPSSLKAMINACWAQDPEQRPTFHQIYKAF
||||| .    ...|| |.||.|.|..||||||   |.| .  ...| ..|...| ||.||. || ..| ... || |||..||.| || . .
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase 93331.m00036.AA Pkinase 22-275 29 9e-66 229.61 Pfam 1-293 (293) Show / Hide
Range on Protein: 22-275
Range on HMM: 1-293/293
Sequence Identity: 29% (86 aa)

FEIHDTIGSGGFSEVFDATFIPTGQRCAVKKLKFKEIKNDEFNLYYR--EIEVLTKLNHPYCLNLIGFSVHRPFII-VTELLQRG----SLYDALRWKDP
..|. .||||.|..|. .. . ||.. |||..| ...| ..     |  ||... .||||. . |...   .. |  |.|... |    .|.| ..  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-WR

EKPL--NGSQKTIIAMCIASGMERLHKLNIIHRDLKSLNILLDNDKLP----RIIDFGLSREV-SESDAIMTMQIGTPHWMAPELFS-SQPYSFKVDVYS
....     .   ..  |..|.| .|. .|||||||. |||.||.  .    .|.||||.. .   ..  ||   |||..||||.   .|.|. |||..|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

YGMLLWEMLTNSSPFKGK------TAAQIMYEVVEKGARPAIPNRCP-------------------SSLKAMINACWAQDPEQRPTFHQIYKA--F
.| .|.|||.   ||.|.      .  |..... ..  .  .|. |.                   ...|  |. |...||..|||..|| .   |
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 93331.m00036.AA Dicty5 95-279 43 4.6e-64 219.15 In-house 76-260 (260) Show / Hide
Range on Protein: 95-279
Range on HMM: 76-260/260
Sequence Identity: 43% (83 aa)

IVTELLQRGSLYDALRWKDPEK----PLNGSQKTIIAMCIASGMERLHKLNIIHRDLKSLNILLDNDKLPRIIDFGLSREVSESDAIMTMQIGTPHWMAP
.|||. ..||| ..|.  | .|    |.   |.  .|. || .|. ||  |||||||||.|.|.  .    ||||| || | .    ||| .||. |||.
HVTEYCHNGSLFNYLN--DQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFV-DNRYHMTMHVGTQCWMAC

ELFSSQPYSFKVDVYSYGMLLWEMLTNSSPFKGKTAAQIMYEVVEKGARPAIPNRCPSSLKAMINACWAQDPEQRPTFHQIYKAFSNGN
||| .|||  |.||||.|  ||||.|  .|..  .   |    | || || ||  ||..   .| .|| | | .||.|  | | |    
ELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIPV-MVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII

Kinase 93331.m00036.AA S_TKc 22-276 28 1.6e-63 218.26 SMART 1-231 (231) Show / Hide
Range on Protein: 22-276
Range on HMM: 1-231/231
Sequence Identity: 28% (76 aa)

FEIHDTIGSGGFSEVFDATFIPTGQRCAVKKLKFKEIKNDEFNLYYREIEVLTKLNHPYCLNLIGFSVHRPFIIVTELLQR--GSLYDALRWKDPEKP--
.||...||.|.|..|. .. . ||...|.|..|         .  .|||..| | .||.  .|... ..  . .|.|..    |.|.| .. . ....  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LNGSQKTIIAMCIASGMERLHKLNIIHRDLKSLNILLDNDKLPRIIDFGLSREVSESDAIMTMQIGTPHWMAPELFSSQPYSF-KVDVYSYGMLLWEML
 ..  .   ..  |....| .|...|||||||  |||||.     |.||||.|..       | ..|||..||||..   .|.. |.|..| | .|.|||
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TNSSPFKGKTAAQIMYEVVEKGARPAIPNRCPSSLKAMINACWAQDPEQRPTFHQIYK--------AFS
.   ||      | |....            ....| .|. |.  |||.|||  .. .         . 
CGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 93331.m00036.AA TyrKc 22-275 29 3.8e-63 217.02 SMART 1-280 (280) Show / Hide
Range on Protein: 22-275
Range on HMM: 1-280/280
Sequence Identity: 29% (86 aa)

FEIHDTIGSGGFSEVFDATFIPTGQRCAVKKLKFKEIKNDEFNLYYREIEVLTKL--NHPYCLNLIGFSVH--------RPFIIVTELLQRGSLYDALRW
 .  ...|.| | ||. .| .   . .|||.||            .||.....||  .||  ..|.|  ..         |  ||.|.   |.| | || 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KDPEKPLNGSQKTIIAMCIASGMERLHKLNIIHRDLKSLNILLDNDKLPRIIDFGLSREVSES-------DAIMTMQ-IGTP-----HWMAPELFSSQPY
. |.  |. ...  ..  ||.||| ||. |.|||||   |.|.....  .| ||||||.. .        | .....  |.       ||||| .    .
HRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

SFKVDVYSYGMLLWEMLTNSSPFKGK-----TAAQIMYEVVEKGARPAIPNR--------CPSSLKAMINACWAQDPEQRPTFHQIYKAF
..| ||.|.| ..||..|.  .           .| ..| |..| |. .|          ||. .  ..  ||. |||.|||| .|.. |
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 93331.m00036.AA LRRK 22-277 28 7.3e-63 215.15 In-house 1-351 (351) Show / Hide
Range on Protein: 22-277
Range on HMM: 1-351/351
Sequence Identity: 28% (101 aa)

FEIHDTIGSGGFS-EVFDATFI-----------------------PTGQRC---AVKKLKF--------------------------------KEIKNDE
..|   ||.|||  .|. |...                       ..  .|   |.||...                                 | .   
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FNLYYREIEVLTKLNHPYCLNLIGFSVHRPFIIVTELLQRGSLYDALRWKDPEK------PLNGSQKTIIAMCIASGMERLHKLN--IIHRDLKSLNILL
|... .|. .. .||||. ..|.||. ..|...|.|... |.||. |. |   .       .. . |  ||. ||.||| ||. |  |||||||| ||||
FREFRHEVWIMSHLNHPNIVSLKGFC-IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

DNDKLP------------RIIDFGLSR--EVSESDAIMTMQIGTPHWMAPELFSSQ---PYSFKVDVYSYGMLLWEMLTNS-SPFKGKT-AAQI--MYEV
   . .             |.|||.||   .  . .....  |.| |||||         |. |||.||.||.||| || .  || . .  ...  |...
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGC-VGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI

VE---KGARPAIPNR-CPS-----SLKAMINACWAQDPEQRPTFHQIYKAFSN
 .   .| || ||.  ||      .... |. ||..||..||.| || |  | 
EDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase 93331.m00036.AA Dicty4 22-277 35 3.7e-62 206.17 In-house 1-277 (277) Show / Hide
Range on Protein: 22-277
Range on HMM: 1-277/277
Sequence Identity: 35% (98 aa)

FEIHDTIGSGGFSEVFDATFIPTGQRCAVKKLKFKEIK--NDEFNLYYREIEVLTKLNHPYCLNLIGFSV---HRP--FIIVTELLQRGSLYDALRW---
  | . ||.|.|.||. .|    |.  |||||. . ..   .. |   .|.. . |. ||  . . | .      |  . ||||.. .|.||  |.    
INIEQRIGKGSFGEVYKGTW--RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

-KDPEKPLNGSQKTI---IAMCIASGMERLHK--LNIIHRDLKSLNILLDNDKLPRIIDFGLSR----EVSESDAIMTMQIGTPHWMAPELFSSQPYSFK
 . ....|  .  .    .|  .| ||  ||    .|||||||| |.| | ..   . |||||.    . . .|  ||. .||| |||||   .|||  |
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTA-CGTPCWMAPEVMMHQPYNEK

VDVYSYGMLLWEMLTNSSPFK--GKTAAQIMYEVVEKGARPAIPNRCPSSLKAMINACWAQDPEQRPTFHQIYKA--FSN
.||||.|..|||.||   |.   ..   |.   |..|. || ||. || |.|. |. ||  ||..||.| .| ..     
ADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase 93331.m00036.AA Pkinase_Tyr 22-275 31 4e-59 200.86 Pfam 1-270 (270) Show / Hide
Range on Protein: 22-275
Range on HMM: 1-270/270
Sequence Identity: 31% (85 aa)

FEIHDTIGSGGFSEVFDATFI----PTGQRCAVKKLKFKEIKNDE---FNLYYREIEVLTKL-NHPYCLNLIGFSV--HRP--FIIVTELLQRGSLYDAL
 ..  ..|.| | ||. .|       |.. .|||.|  ||   .|        ||......| .||  ..|.|  .   .|   .||.|. . |.|.| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RWK-DPEKPLNGSQKTIIAMCIASGMERLHKLNIIHRDLKSLNILLDNDKLPRIIDFGLSREVSESDAIMTMQIGT-----PHWMAPELFSSQPYSFKVD
| . ....||. ...  ... ||.||| |.  |.|||||   |.|.....  .| ||||.| . ..|    .. ..       ||||| ..   .. | |
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSD

VYSYGMLLWEMLTNS-SP-FKGKTAAQIMYEVVEKGARPAIPNRCPSSLKAMINACWAQDPEQRPTFHQIYKAF
|.|.| |.||..|   .| ..| . ....  . |.| | ..|  ||  .  ..  ||..|||.|||| .|.  .
VWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase 93331.m00036.AA HH498 22-275 33 3.5e-57 179.65 In-house 1-284 (284) Show / Hide
Range on Protein: 22-275
Range on HMM: 1-284/284
Sequence Identity: 33% (96 aa)

FEIHDTIGSGGFSEVFDATFIPTGQRCAVKKLKFKEIKNDEF------NLYYREIEVLTKLNHPYCLNLIGFSVHRP--FIIVTELLQRGSLYDAL----
.| | .|||| | .|.  ..   .   |||  . . .             . ||. .. .||||.    .. ..  |  | |||.  . |||.  |    
IEFHEKIGSGSFGKVYKGEW--RNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIP

-----------RWKDPEKPLNGSQKTIIAMCIASGMERLHK---LNIIHRDLKSLNILLDNDKLPRIIDFGLSREVSE-SDAIMTMQIGTPHWMAPELFS
             |  .  .    | .|.. .| ||. ||      |||||| | |||.. |    . ||| || | .  |  || |.| . ||||| ||
IGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFS

-SQPYSFKVDVYSYGMLLWEMLTNSSPFKGKTAAQIMYEVVEKGARPAIPNR----CPSSLKAMINACWAQDPEQRPTFHQIYKAF
 .| || ||||.||.| .|||.|   ||     |    |.  .  || ||.      | .   .|  || . || ||.| ||    
QCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL

Kinase 93331.m00036.AA TK 22-275 17 4.7e-53 175.81 In-house 1-486 (486) Show / Hide
Range on Protein: 22-275
Range on HMM: 1-486/486
Sequence Identity: 17% (85 aa)

FEIHDTIGSGGFS---EVFDATFIPTG-------------------------QRCAVKKLKFK-EIKNDEFNL--------------YYREIEVLT--KL
 .. ...|.| |    ||. .. .. .                         ...||| || . .   .|| .                .|....   ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

NHPYCLNLIGFSVHR-------------PFIIVTELLQRGS----LYDALRWKDPEKP------------------------------------------
.||  ..|.| ...              |..||.|. . |.    | | || ..|..                                           
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LNGSQKTIIAMCIASGMERLHKL------NIIHRDLKSLNILLDNDKL-----------PRIIDFG---
                               |.  |.  ... ||.||| ||..      |..||||   |.|.....             .| |||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSREVSESDAIMTMQ-IGTPH-------------------------WMAPELFSSQP---------YSFKVDVYSYGMLLWEMLTNS-SPFKGKT
     |.|.. ..|   ...  ||.                          ||||| . ..          .. | ||.|.| |.||..|.   |. |  
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

AA---------QIMYEVVEKG--------------ARPAIPNRCP--------------SSLKAMINACWAQDPEQRPTFHQIYKAF
           | ..| ...|               |.. |  ||                .  ..  ||. |||.|||| |.....
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase 93331.m00036.AA Dicty4-Unclassified 22-275 32 6.8e-52 176.0 In-house 1-263 (263) Show / Hide
Range on Protein: 22-275
Range on HMM: 1-263/263
Sequence Identity: 32% (88 aa)

FEIHDTIGSGGFSEVFDATFIPTGQRCAVKKLKFKEIKND--EFNLYYREIEVLTKLNHPYCLNLIGFSVHRP------FIIVTELLQRGSLYDALR--W
  |   || | ||.|     .  |   ||||.     |        . .|.|.|  . ||  . . | ..  |      ..||.|.. .| |        
IQIDQFIGKGHFSKVHKG--NWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCIN-PRSHKSTMCIVMEFMHKGNLFEVIHSKP

KDPEKPLNGSQ--KTIIAMCIASGMERLHKLNIIHRDLKSLNILLDNDKLPRIIDFGLSREVSESDAIMTMQIGTPHWMAPELFSSQPYSFKVDVYSYGM
 . ..|.         .|. || ||  ||  |.||||.|| |||.| .   .| |||.||...     ||   ||| | .||      |  | |||||.|
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFN-MTTIAGTPKWESPECLMHESYNQKSDVYSYAM

LLWEMLTNSSPFKGKT-AAQIMYEVVEKGARPAIPNRCPSSLKAMINACWAQDPEQRPTFHQIYKAF
.|.|..|   |. .      .   | .|. || ||  |.  .| .|  ||  ||  |||. || .  
MLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL

Kinase 93331.m00036.AA STE 22-276 21 9.2e-52 178.28 In-house 1-359 (359) Show / Hide
Range on Protein: 22-276
Range on HMM: 1-359/359
Sequence Identity: 21% (79 aa)

FEIHDTIGSGGFSEVFDATFI------PTGQR---------CAVKKLKFKEIKN---------------DEFNLYYREIEVLTKLN--HPYCLNLIGFSV
.|. . ||.|.| .|. |  .      .||.          .|.|...... .|               .|.. . .||... |.|  ||.  . .|  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

HRP--------FIIVTELLQRGSLYDALR--WKDPE---------KPLNGSQKTIIAMCIASG-MERLHKLNIIHRDLKSLNILLDNDKLPRIIDFGLSR
.            |. |..  ||| | ..  .. ..         .... ||  .|.  |  | .. ||...|||||.|. ||||       ..|||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

EVSE---------------SDAIMT-MQIGTPHWMAPELFSS------QPYSFKVDVYSYGMLLWEMLTNSSPFKGKTAAQIMYEVVEK-----------
 ...               . . ..   .||| |||||  .       ..|..|.|..| | ...||.|   |.   .  . |..   .           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---GARPAIPN-------------------RCPSSLKAMINACWAQDPEQRPTFHQIYK---AFS
   |  | .|.                   .. ...|  || |   ||..||| .|  |    | 
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI