Gene 89419.m00154 (T.vaginalis)

89419.m00154

Species: T.vaginalis
Alias: TvagK0402, 89419.m00154
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
89419.m00154.AA Protein None 437 None Fasta, JSON
89419.m00154.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 89419.m00154.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 89419.m00154.AA PH 10-100 23 2e-06 25.83 Pfam 4-92 (92) Show / Hide 
Range on Protein: 10-100
Range on HMM: 4-92/92
Sequence Identity: 23% (22 aa)

EGWVKKKWLFGRWIKRFCVLQGSQLMIWKDD---KKENVDL-TIEITPDTKILILKSKKNRKFYVEDPMGNSATLKTKRSEQMMLWVLILRAVTF
|||..||  ...| ||..||....|...|||   .|  ..| ....|....      |..  |..   .... ..... .|.|  |.  ....  
EGWLHKKGKRKSWKKRWFVLFNNCLYYYKDDKYRPKGSIPLSDCQVTKVPDN-----KRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR
PH 89419.m00154.AA PH 7-102 21 7.1e-05 23.44 SMART 1-82 (82) Show / Hide 
Range on Protein: 7-102
Range on HMM: 1-82/82
Sequence Identity: 21% (21 aa)

SNPEGWVKKKWLFGRWIKRFCVLQGSQLMIWKDDKKENVDLTIEITPDTKILILKSKKNRKFYVEDPMGNSATLKTKRSEQMMLWVLILRAVTFNN
   |||..||  . || ||..|| ...|...||.       .| ..   ..   .      |..    . . ..... .|.|  |.  ..... ||
VIKEGWLYKKS-K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDC-TVRE-P-----CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN
Kinase 89419.m00154.AA AGC 110-361 29 1.7e-148 386.92 In-house 1-395 (395) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-395/395
Sequence Identity: 29% (118 aa)

FEIISVIGKGCYGKVRLVKSK------STGEVFAIKSIRKSK---LIQQNRIHTVIAE------------RNILSKAN----------HPFIVA-LRFAF
||.. ||||| .|||.||. |      .||...|.| ..|..   ....| .. ...|            ||||.|.|          |||||  | ..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTPAK--FYLGLEYVP---------GG-ELYTRIH---RDGYLSKMEYKMVIAQ-------IAIALNYLHS-IGIVYRD-IKPENILIGADGYIKLADFG
|.. .   |. .||.|         || ||.....   . |...  . .  .|.       |. || ||||  ||..|| .||||||. .||.|||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAKDIITDN---------------------------------------------------KTTSFCG--TPKYIAPETIVGVPYDQSVDWWS--LGILTY
|.| ...|.                                                   .|..|||  || |.||| .    |....||||  ||.| |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

QLIYHKFPFYSQNVD----------AVYRMIL------NKKVEFP----------DSASPEEIDFISILLEKDPKKRAG----------YNEVSQHPFF
.... . |||..|..           ..  |.      |.||.||          .. |||  |.|. ||.|||.|| |          ..|. .||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 89419.m00154.AA Akt 110-361 45 3.2e-122 392.52 In-house 1-264 (264) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-264/264
Sequence Identity: 45% (119 aa)

FEIISVIGKGCYGKVRLVKSKSTGEVF-AIKSIRKSKLIQQNRIHTVIAERNILSKANHPFIVALRFAFQTPAKFYLGLEYVPGGELYTRIHRDGYLSKM
|... |.||| .||| ||| |.|.... |.|...|...||.| .  ...||||| . |||||| | ..|||. | |. ..|..||||.. ..|... |  
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

EYKMVIAQIAIALNYLHSIGIVYRD-IKPENILIGADGYIKLADFGLAKDI-ITD-NKTTSFCGTPKYIAPETIVGVPYDQSVDWWS-LGILTYQLIYHK
. .  .|.|  |. .||| .|.|||  ||||||. .||.|.|.||||.|.. |.|  ||..||||| |.||| . |. ....||||. ||...| ...  
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

FPFYSQNVDAVYRMILNKKVEFP--DSASPEEIDFISILLEKDPKKRAG--YN---EVSQHPFF
 |||.|...  .  |.|..|.||  |  |||  |.|| ||.|||||| |  .|   |. .||.|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 89419.m00154.AA SGK 110-361 39 5.8e-115 356.56 In-house 1-283 (283) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-283/283
Sequence Identity: 39% (112 aa)

FEIISVIGKGCYGKVRLVKSKST------------------GEVFAIKSIRKSKLI-------QQNRIHTVIAER-NILSKANHPFIVALRFAFQTPAKF
|....||||| .||| .|| |..                  . ..|.| ..|   |       . .    . ||| .||.. .||||| |..||||. | 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLGLEYVPGGELYTRIHRDGYLSKMEYKMVIAQIAIALNYLHSIGIVYRDIKPENILIGADGYIKLADFGLAK-DIITDNKTTSFCGTPKYIAPETIVGV
|. ..|| |||.   . | ....  . .   |.|. || ||||. |.||| |||||| ...|...| ||||.| .| | ..|..||||| | ||| . . 
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYDQSVDWWSLGILTYQLIYHKFPFYSQNVDAVYRMILNKKVEFPDSASPEEIDFISILLEKDPKKRAGYN----EVSQHPFF
|.| .||||.||.. | ..| . ||||.|.   |  |.|..  .| . |..  | |  ||.|||||| | .    |. .||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 89419.m00154.AA S_TKc 110-361 35 1.5e-103 351.19 SMART 1-231 (231) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-231/231
Sequence Identity: 35% (96 aa)

FEIISVIGKGCYGKVRLVKSKSTGEVFAIKSIRKSKLIQQNRIHTVIAERNILSKANHPFIVALRFAFQTPAKFYLGLEYVPG--GELYTRIHRDGY---
.||. .|||| .|||.... |.||...||| |.           ... |..||.| .||.|| |  .||.  ..|. .||..|  |.|...|.. |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LSKMEYKMVIAQIAIALNYLHSIGIVYRDIKPENILIGADGYIKLADFGLAKDIITDNKTTSFCGTPKYIAPETIVGVPYDQ-SVDWWSLGILTYQL
   ..  . . ...||. ||.|.|| ||..||.||||||.     ||..|||||. .      |.||||| |.||| .   .|.  ..||||.|.. | .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

IYHKFPFYSQNVDAVYRMILNKKVEFPDSASPEEIDFISILLEKDPKKRAGYNEVSQ-------HPFF
.. . ||.  ........|.          ||| .|||. .|.|||.|| .  |. |       ||.|
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 89419.m00154.AA AktR 110-361 41 1.1e-100 340.74 In-house 1-268 (268) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-268/268
Sequence Identity: 41% (111 aa)

FEIISVIGKGCYGKVRLVKSK-STGEVFAIKSIRKSKLIQQNRIHTVIAERNILS-KANHPFIVALRFAFQTPAKFYLGLEYVPGGELYTRIHRDGYLSK
|... ..||| .||| ||. |  .....|.|.|.|.|.|..|..| .| ||||.  ..|||||| | ..|||  | .. .||.|||||.. . ... .| 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

MEYKMVIAQIAIALNYLHSI-GIVYRDIKPENILIGADGYIKLADFGLAK-DII--TDNKTTSFCGTPKYIAPETIVG-VPYDQSVDWWSLGILTYQLIY
.. .  .||| .|| |||.   |.|||.||||||.. ||..|..||||.|  ..   | |..||||||.|.|||.|   .... |||||..||. | ...
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

HKFPFYSQNVDAVYRMILNKK-VEFPDS--ASPEEIDFIS-ILLEKDPKKRAG-----YNEVSQHPFF
   |||..|    . .|..|  ..||..   |..  |.|   || |.|.|| |       |.  ||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 89419.m00154.AA RSK 113-361 37 3.8e-92 312.42 In-house 1-278 (278) Show / Hide 
Range on Protein: 113-361
Range on HMM: 1-278/278
Sequence Identity: 37% (103 aa)

ISVIGKGCYGKVRLVKSK---STGEVFAIKSIRKSKLIQQNR-IHTVIAERNILSKAN-HPFIVALRFAFQTPAKFYLGLEYVPGGELYTRIHRDGY---
..| |.| |||| |.. .    || ..| | ..|.|..| .. . .. .|||||.  . ||||| |  ||||. |.|| .||..||||.|.. . ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LSKMEYKMVIAQIAIALNYLHSIGIVYRDIKPENILIGA---DGYIKLADFGLAKD-IIT-DNKTTSFCGTPKYIAPETIV----GVPYDQSVDWWSLGI
.|  | ....|.|. |. .||. ||..||.||||||      .| ||| |||..|   .   ..| .||.|  |.||| .     .. .|...||||||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LTYQLIYHKFPFYS---QNVDAVYRMILNKK--VEFP--DSASPEEIDFISILLEKDPKKRAG-----YNEVSQHPFF
| | .   . ||..   .| . . . |...|  ...|  .. |.|  |.|. .|..||.|| |      .|. |||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 89419.m00154.AA PKA 110-361 39 9.3e-92 311.14 In-house 1-263 (263) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-263/263
Sequence Identity: 39% (105 aa)

FEIISVIGKGCYGKVRLVKSKSTGEVFAIKSIRKSKLIQQNRIHTVIAERNILSKANHPFIVA-LRFAFQTPAKFYLGLEYVPGGELYTRIHRDGYLSKM
|||| ..|.| .|.|.|...|..|. .|.| ..|.. .. . .. |. |.|||.  .|||||  . . ||.. . |. .|||||||. ... . | .|  
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

EYKMVIA-QIAIALNYLHSIGIVYRDIKPENILIGADGYIKLADFGLAKDIITDNKTTSFCGTPKYIAPETIVGV-PYDQSVDWWSLGILTYQLIYHKFP
. |  .| ||  || ||||  |.||| |||||||  .|.||..||| || . .   | . |||| |.||| | .  ..  |||||.|||| | .   . |
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FYSQ--NVDAVYRMILNKKVEFPDSASPEE---IDFISILLEKDPKKRA-----GYNEVSQHPFF
||    .. . |. |.| |..|| . .. .    |.|. ||..|..||      | | .  |..|
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 89419.m00154.AA Pkinase 110-361 33 6.8e-89 306.43 Pfam 1-293 (293) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-293/293
Sequence Identity: 33% (98 aa)

FEIISVIGKGCYGKVRLVKSKSTGEVFAIKSIRKSKLIQQNRIHTVI-AERNILSKANHPFIVALRFAFQTPAKFYLGLEYVPGG----ELYTRIH--RD
..|...||.| .|.|.. . |.||...|.| |.|..   . ... .  .|  |. . |||.|| |. .|... . |. .||..||    .|...|.  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GYL--SKMEYKMVIAQIAIALNYLHSIGIVYRDIKPENILIGADGYI----KLADFGLAKD--IITDNKTTSFCGTPKYIAPETIV-GVPYDQSVDWWSL
| .  |  | |... ||. .|.|.|| ||..||.|||||||  .|.|    |..||||||   .  .  .|.||||| |.||| |  | .|...||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILTYQLIYHKFPFYSQ------NVDAVYRMILNKKVEFPDSAS---------------------PEEIDFISILLEKDPKKRAGYNEVSQHPFF
|.. |...  ..||...      . ......|. ....|. . .                     .| .|||. .|.|||||| .  .. |||.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 89419.m00154.AA Ciliate-E2 110-361 25 8.8e-85 287.97 In-house 1-365 (365) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-365/365
Sequence Identity: 25% (96 aa)

FEIISVIGKGCYGKVRLVKSKSTGE-----------------------VFAIKSIRKSKLIQQNRIHTVI----------AERNILSKANHPFIVALRFA
...| .||.|..|.|...| .....                        .|.|...|....|....  ..           |.|||.. |||.|. .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--TPAKFYLGLEYVPGGELYTRI-------------------HRDGYLSKMEYK-------MVIAQIAIALNYLHSIG-IVYRDIKPENILIGADGYI
||  .  ..|| .||. ||.|. .|                      .|..|   .       . ||.|  ||.|||| . |..|||||||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLADFGLAKDIITD--------------------------------NKTTSFCGTPKYIAPETIVGVP---------YDQSVDWWSLGILTYQLIYHKFP
|..||||.|.. .|                                | . ..|||| | ||| . | .         || ..|.||||.. |.... |.|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FYSQNVDAVYRMILNKKVEFP------------------DSASPEEIDFISI----LLEKDPKKRAG-YNEVSQHPFF
|        .. |...|..||                  .. |.| .|.|.     .|.|||.|| . .... .||.|
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 89419.m00154.AA Ciliate-E2-Unclassified 110-361 27 2.6e-83 283.09 In-house 1-352 (352) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-352/352
Sequence Identity: 27% (97 aa)

FEIISVIGKGCYGKVRLVKSKSTGEVFAIKSIRKSKLIQQNRIHTV---------IAERN-------------ILSKANHPFIVALRFAFQTPAKFYLGL
..|| .||.|..|||.... |......|.| . |.. . |. | ..         . ...             ||.  .||||| . ..||.  ..|. .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYVPGG-----------------ELYTRIHRDGYLSKMEYK-----MVIAQIAIALNYLHSIG-IVYRDIKPENILIGADG---YIKLADFGLAKDIITD
||..||                 .|. .....  ..  . |       .|||  .|.|||. . |..|||||||||.  .|   |||..|||..| ....
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

----------------NKTTSFCGTPKYI----APETIVGVPYDQS----VDWWSLGILTYQLIYHKFPFYSQNVDA----------------VYRMILN
                .....||||| |.    ||| . |  ||.|    .|.||||.. |.... ..|||..| .                 .|. |..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

KKVEFP--------DSASPEEIDFIS----ILLEKDPKKRAGYNEVSQHPFF
|...||        .  ||| .|||.     .|.|.|.|| ..... .||.|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 89419.m00154.AA MAST 110-256 43 1.1e-59 180.71 In-house 1-150 (337) Show / Hide 
Range on Protein: 110-256
Range on HMM: 1-150/337
Sequence Identity: 43% (65 aa)

FEIISVIGKGCYGKVRLVKSKSTGEVFAIKSIRKSKLIQQNRIHTVIAERNILSKANHPFIVALRFAFQT--PAKFYLGLEYVPGGELYTRIHRDG-YLS
||.| .|.|| ||.| ||| |.|.. ||.|.|... .|  | . .|..|||||. .  ||.| .  .|||    . .. .||. ||   . ..  |  . 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

KMEYKMVIAQIAIALNYLHSIGIVYRDIKPENILIGADGYIKLADFGLAK
  . || ||.. ..| |||| ||| ||.||.|.|| ..| |||.||||.|
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase 89419.m00154.AA MAST 110-256 47 5.3e-58 185.43 In-house 1-147 (334) Show / Hide 
Range on Protein: 110-256
Range on HMM: 1-147/334
Sequence Identity: 47% (70 aa)

FEIISVIGKGCYGKVRLVKSKSTGEVFAIKSIRKSKLIQQNRIHTVIAERNILSKANHPFIVALRFAFQTPAKFYLGLEYVPGGELYTRIHRDGYLSKME
||.| .|.|| |||| ||| |.|.. ||.| |.|| .|  | ...|..|||||. .  ||.| .  .|||  . .. .||. || . . .|  ||.    
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

YKMVIAQIAIALNYLHSIGIVYRDIKPENILIGADGYIKLADFGLAK
 || ||.....| |||| ||| ||.||.|.|| ..| |||.||||.|
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase 89419.m00154.AA MAST 268-361 41 2.7e-33 98.6 In-house 229-337 (337) Show / Hide 
Range on Protein: 268-361
Range on HMM: 229-337/337
Sequence Identity: 41% (45 aa)

CGTPKYIAPETIVGVP-YDQSVDWWSLGILTYQLIYHKFPFYSQNVDA-VYRMILN--KKVEFPDS--------ASPEEIDFISILLEKDPKKRAGYN--
|||| ||||| | | . | ..|||||.||  | ..    ||   ..   .   |.|  ...|.|.          ||| .| |. ||...|||| | |  
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGA

-EVSQHPFF
 |. |||||
DEIKQHPFF
Kinase 89419.m00154.AA MAST 268-361 41 5.3e-31 96.92 In-house 225-334 (334) Show / Hide 
Range on Protein: 268-361
Range on HMM: 225-334/334
Sequence Identity: 41% (46 aa)

CGTPKYIAPETIVGVP-YDQSVDWWSLGILTYQLIYHKFPFYSQNVDAVYRMILNKK---VEFPDS--------ASPEEIDFISILLEKDPKKRAGYN--
|||| ||||| | | . . ..|||||.||  |...    ||   ... ..  |||..   .|.|.          ||| .| |. ||. ||.|| | |  
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG

--EVSQHPFF
  || |||||
ADEVKQHPFF
Kinase 89419.m00154.AA TyrKc 110-361 20 3e-14 7.64 SMART 1-280 (280) Show / Hide 
Range on Protein: 110-361
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

FEIISVIGKGCYGKVRLVKSKSTGEVFAIKSIRKSKLIQQNRIHTVIAERNILSKA--NHPFIVALRFAFQTP-------AKFYLGLEYVPGGELYTRIH
 . . ..| |..|.|.. . |   .  |.|......      .   . | .|..|   .|| ||.|  .  ..          .. .||.|.| |  ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RDGY-LSKMEYKMVIAQIAIALNYLHSIGIVYRDIKPENILIGADGYIKLADFGLAKDIITD--------NKTTSF--CGTP----KYIAPETIVGVPYD
. .  |.  .      |||   .|||| ... ||.   |.|.|... .| .||||..||  |         ....   .|      .  |||.|    . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

QSVDWWSLGILTYQLI-YHKFPFYS-----QNVDAVYRMILNK-KVEFPDS--------ASPEEIDFISILLEKDPKKRAGYNEVSQHPFF
   | || |.. . .  | . | .       . . |.. . .    . |..        ...|  . ..   . ||..|   .|.  | .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 89419.m00154.AA Pkinase_Tyr 110-258 25 7.5e-11 37.38 Pfam 1-161 (270) Show / Hide 
Range on Protein: 110-258
Range on HMM: 1-161/270
Sequence Identity: 25% (41 aa)

FEIISVIGKGCYGKVRLVKSK----STGEVFAIKSIRKSKLIQQN-RIHTVIAERNILSKA-NHPFIVALRFAFQ-TPAK--FYLGLEYVPGGELYTRIH
 ... ..|.|..|.|.. . |    .|.   |.|.. | .  ...  .   ..| .|...  .|| || |  .          |. .||.|.| |..  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

R----DGYLSKMEYKMVIAQIAIALNYLHSIGIVYRDIKPENILIGADGYIKLADFGLAKDI
.    .. |.  .     .||| ...||.|.... ||.   |.|.. .. .| .|||||.||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase 89419.m00154.AA S_TK_X 362-422 21 2e-06 28.81 SMART 1-79 (79) Show / Hide 
Range on Protein: 362-422
Range on HMM: 1-79/79
Sequence Identity: 21% (17 aa)

SEFTFEDILN--KKLTPEYIPNLE----EPTEVKYFDPIFTSEIKADSYVPP----IVGSEA--------CIPGFSYVD
... .....|  |...| ..|..      || ...||| ||.|   .. ..|    ... ..        . .||.|| 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF