Gene 93440.m00483 (T.vaginalis)

93440.m00483

Species: T.vaginalis
Alias: TvagK0423, 93440.m00483
External Links:
Annotation:

Classification

Group: AGC
Family: NDR
Subfamily: NDR-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
93440.m00483.AA Protein None 478 None Fasta, JSON
93440.m00483.kin_dom Protein Kinase Domain None 287 None Fasta, JSON

Protein domain

Protein domains of 93440.m00483.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93440.m00483.AA AGC 112-398 28 3.3e-139 362.35 In-house 1-395 (395) Show / Hide 
Range on Protein: 112-398
Range on HMM: 1-395/395
Sequence Identity: 28% (114 aa)

FEKIQIIGRGSFGEVWLVKDK------TDQHVYAMKVLKKRI---LIQRNQILNTIVE------------KDFYTQYD----------NPWSAK-LYYSF
|| . .||.||||.|.||..|      . ...||||||||.    ....|.. .|..|            ..  ....          .|.  | |.|||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDQNH--LYLIMEFLP--------GGDLMNLLIHRN-----ILTETETKFLIAE-------AALAIHHVHL-QGFIHRD-IKPDNLLLTKDGHVRLIDFG
||..|  ||..||..|        ||... .|. ..     ...| ...| .||        .||... |  .|.|||| .||.|.||..|||..| |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSTKINRFGDPMVKVIDLITDAFHECAGI----------NVEHHKHQKYNR-------------FVCSAVG--TTDYIAPEVLMKKSYGPNADFWS--LG
|...... |.. .. .. . . ||.              . .. .. . |.                . .|  | .|.|||.|    ||. .| ||  ||
LCKEGMNDGEKGQQ-SQSN-MKFHW-HNKKYQKSNMDTNK-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLG

AIMFEMLYGYAPFMSSNPQ----------LTANKIIH----FEESLIFPPT--------PVVSKEAIALMRGLLT-DSENRMT----------FEEIKQH
..|.|||.|| || . |||           . .||..    ... . ||.         . .|.||  |...||. | |.| .          .||||.|
CLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNH

PFF
|.|
PWF
Kinase 93440.m00483.AA NDR 112-398 39 2.5e-130 404.43 In-house 1-350 (350) Show / Hide 
Range on Protein: 112-398
Range on HMM: 1-350/350
Sequence Identity: 39% (137 aa)

FEKIQIIGRGSFGEVWLVKDK-TDQHVYAMKVLKKRILIQRNQILNTIVEKDFYTQYD--NPWSAKLYYSFQDQNHLYLIMEFLPGGDLMN---LLIHRN
||.| |||.|.|||||||. | | .|.||||...|   ...||. .   |.|  .. |  |||  |||||||| ..|||.||..||||.|    ||.  .
FEIIKIIGKGAFGEVWLVRKKDT-GHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMD

ILTETETKFLIAEAALAIHHVHLQGFIHRDIKPDNLLLTKDGHVRLIDFGLSTK--------------------------INRFGDPMVKVIDLITDAFH
|.|| ...| ||| ..||. ||  |.|||||||||.|. ||||. |.||||.|                           ....   | ..    . .. 
IFTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNW

ECAG------------------INVEHHKHQKYNR--FVCSAVGTTDYIAPEVLMKKS-YGPNADFWSLGAIMFEMLYGYAPFMSSNPQLTANKIIHFEE
....                   .| . .  | ||     |.||| ||.||||...|  |..  |.||||.||.||| ||.|| |..|| |  ||.....
NSNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQ

SL-----IFPPTPVVSKEAIALMRGLLT-DSENRMT-----FEEIKQHPFF
 .      |||   .|.||  | | |.. | ..|       ..|||.||||
TWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase 93440.m00483.AA S_TKc 112-398 28 8.7e-91 308.84 SMART 1-231 (231) Show / Hide 
Range on Protein: 112-398
Range on HMM: 1-231/231
Sequence Identity: 28% (87 aa)

FEKIQIIGRGSFGEVWLVKDKTDQHVYAMKVLKKRILIQRNQILNTIVEKDFYTQYDNPWSAKLYYSFQDQNHLYLIMEFLPG--GDLMNLLIHRNI---
.|....||.|.||.|.....| .....|.|..|           ... | .   . . |.  |||..||| .|||..||...|  |||. .. .|.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTETETKFLIAEAALAIHHVHLQGFIHRDIKPDNLLLTKDGHVRLIDFGLSTKINRFGDPMVKVIDLITDAFHECAGINVEHHKHQKYNRFVCSAVG
   ..| ...|.... ..|. . | .|.||||.||.|.||..  |. ..||||....                                       . .|
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------------------------------TTFCG

TTDYIAPEVLMKKSYGP-NADFWSLGAIMFEMLYGYAPFMSSNPQLTANKIIHFEESLIFPPTPVVSKEAIALMRGLLT-DSENRMTFEEIKQ-------
| .|.|||||   .||.  .| ||.| |..|||.|| ||   ..|.. .||               |.||. ..|..|. | |.|.|  |. |       
TPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

HPFF
||.|
HPWF
Kinase 93440.m00483.AA RSK 115-398 31 7.7e-77 261.59 In-house 1-278 (278) Show / Hide 
Range on Protein: 115-398
Range on HMM: 1-278/278
Sequence Identity: 31% (96 aa)

IQIIGRGSFGEVWLVKDK---TDQHVYAMKVLKKRILIQRNQ-ILNTIVEKDFYTQYD-NPWSAKLYYSFQDQNHLYLIMEFLPGGDLMNLLIHRNI---
..  |.|..|.| |.. .     ...||||||||. ..||.  .  |  | .    .   |   .|.|.||.. .||||||...||.|   | .. .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LTETETKFLIAEAALAIHHVHLQGFIHRDIKPDNLLLTK---DGHVRLIDFGLSTK-INRFGDPMVKVIDLITDAFHECAGINVEHHKHQKYNRFVCSAV
..|.| .| .|| .||. | | ||.||||.||.| |..    .||..|.|||.. .  .... .. .                                .
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMT-------------------------------FC

GTTDYIAPEVLM---KKS-YGPNADFWSLGAIMFEMLYGYAPFMS---SNPQLTANKIIHFEESLIFPPTPVVSKEAIALMRGLLT-DSENRMT-----F
.| .|.|||.|.   ... .. ..| ||||..|.||| |. || .   .|.. . ..| . . || .|  . .|.||  | |..|. | ..| .      
YTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDA

EEIKQHPFF
|||||||.|
EEIKQHPWF
Kinase 93440.m00483.AA Ciliate-E2-Unclassified 112-398 25 1.2e-73 251.03 In-house 1-352 (352) Show / Hide 
Range on Protein: 112-398
Range on HMM: 1-352/352
Sequence Identity: 25% (97 aa)

FEKIQIIGRGSFGEVWLVKDKTDQHVYAMKVLKKRILIQRNQI------------LNTIVEKDFYT-----------QYDNPWSAKLYYSFQDQNHLYLI
...|..||.|.||.|.....| .. .|||| .|| . . ..||            .| . . ..             . ..|   |..| |||....|..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEFLPGGDLMNLLIHR-----------------NILTETETK-----FLIAEAALAIHHVHLQG-FIHRDIKPDNLLLTKDG---HVRLIDFGLSTKIN-
||...||||.. . .|                 .|.|| ..|     |..|.  ... . | .. .|||||||.|.|....|   ....||||.| |.. 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

-----RFGDPMVKVIDLITDAFHECAGINVEHHKHQKYNRF----VCSAVGTTDYI----APEVLMKKSYGPN----ADFWSLGAIMFEMLYGYAPFMSS
      ..                         . ||....     .. .||  |.    |||||... |.      .|.|||| |..|||.|| || . 
NNNCDTNQ-------------------------Q-QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDN

N----PQLTANKIIH------FEESLI-----FPPTP------VVSKEAIALMR-----GLLTDSENRMTFEEIKQHPFF
|     ||....| .      ...  .     ||. |       .|.||. . .      |  . ..|.|||.|..||.|
NCEQHQQLITQWI-NNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 93440.m00483.AA DMPK 112-262 44 2.7e-73 180.15 In-house 1-152 (270) Show / Hide 
Range on Protein: 112-262
Range on HMM: 1-152/270
Sequence Identity: 44% (67 aa)

FEKIQIIGRGSFGEVWLVKDKTDQHVYAMKVLKKRILIQRNQILNTIVEKDFYTQYDNPWSAKLYYSFQDQNHLYLIMEFLPGGDLMNLLIHRN-ILTET
|| . .|||| |||| .|. |. . |||||...|  .. | .      |.|     . .|  .|.| ||| |.||..||. ||||| .|.      . | 
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

ETKFLIAEAALAIHHVHLQGFIHRDIKPDNLLLTKDGHVRLIDFGLSTKINR
 ..| .||  |||| .|  |..|||||||| || . ||..| |||   |.||
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFGSCMKMNR
Kinase 93440.m00483.AA MAST 112-257 40 7.5e-63 190.57 In-house 1-149 (337) Show / Hide 
Range on Protein: 112-257
Range on HMM: 1-149/337
Sequence Identity: 40% (61 aa)

FEKIQIIGRGSFGEVWLVKDKTDQHVYAMKVLKKRILIQRNQILNTIVEKDFYTQYDNPWSAKLYYSFQD--QNHLYLIMEFLPGGDLMNLLIHRN-ILT
|| | .|..| .| |.||| |.    .||||.... .| .||. . .||..  |.|.||.  |..||||    ..|...||.. |||   || . .  . 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

ETETKFLIAEAALAIHHVHLQGFIHRDIKPDNLLLTKDGHVRLIDFGLS
| ..|. |||  |..   | .| .|||.||||.|....||. | |||||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase 93440.m00483.AA MAST 112-257 42 4.1e-61 195.62 In-house 1-146 (334) Show / Hide 
Range on Protein: 112-257
Range on HMM: 1-146/334
Sequence Identity: 42% (62 aa)

FEKIQIIGRGSFGEVWLVKDKTDQHVYAMKVLKKRILIQRNQILNTIVEKDFYTQYDNPWSAKLYYSFQDQNHLYLIMEFLPGGDLMNLLIHRNILTETE
|| | .|..| .| |.||| |.    .||||.||. .| .|.. . .||..  ..|.||.  |..||||  |.|...||.. |||.  || . . . |  
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

TKFLIAEAALAIHHVHLQGFIHRDIKPDNLLLTKDGHVRLIDFGLS
.|. ||| .|..   | .| .|||.||||.|....||. | |||||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase 93440.m00483.AA Akt 112-257 43 7.8e-61 193.16 In-house 1-148 (264) Show / Hide 
Range on Protein: 112-257
Range on HMM: 1-148/264
Sequence Identity: 43% (65 aa)

FEKIQIIGRGSFGEVWLVKDKTDQHVY-AMKVLKKRILIQRNQILNTIVEKDFYTQYDNPWSAKLYYSFQDQNHLYLIMEFLPGGDLMNLLIHRNILTET
|. . ..|.|||| | |||.| .| .| |||||||. .||.||. .|. |.     ...|   .|.||||.|..||..|.. .||.| ..| .... .| 
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

ETKFLIAEAALAIHHVHLQGFIHRD-IKPDNLLLTKDGHVRLIDFGLS
...| .||  ||| | | .. | ||  || |.|. ||||..| ||||.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLC
Kinase 93440.m00483.AA Pkinase 174-398 25 1.6e-51 182.31 Pfam 64-293 (293) Show / Hide 
Range on Protein: 174-398
Range on HMM: 64-293/293
Sequence Identity: 25% (68 aa)

KLYYSFQDQNHLYLIMEFLPGG----DLMNLLI--HRNIL--TETETKFLIAEAALAIHHVHLQGFIHRDIKPDNLLLTKDGHV----RLIDFGLSTKIN
.||..|.| .|.|..||...||    ||. ..    .. .  .| | || . . . .. . | .|.||||.||.|.|. ..||.    ...||||. ...
RLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD

RFGDPMVKVIDLITDAFHECAGINVEHHKHQKYNRFVCSAVGTTDYIAPEVLM-KKSYGPNADFWSLGAIMFEMLYGYAPFMSS------NPQLTANKII
                                 |.   . .|| .|.||||..  . ||| .| ||.| |..||| |. || ..      ...   ..| 
------------------------------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIM

HFEESLIFPPTPVVS-----------------KEAIALMRGLLT-DSENRMTFEEIKQHPFF
. . .  .| .  .|                 .|.. .....|. | . | |.|.|.|||.|
GPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 93440.m00483.AA AktR 112-257 40 6.1e-51 175.55 In-house 1-149 (268) Show / Hide 
Range on Protein: 112-257
Range on HMM: 1-149/268
Sequence Identity: 40% (61 aa)

FEKIQIIGRGSFGEVWLVKDK-TDQHVYAMKVLKKRILIQRNQILNTIVEKDFYT-QYDNPWSAKLYYSFQDQNHLYLIMEFLPGGDLMNLLIHRNILTE
|. ....|.| ||.| ||..| ..| .||||..||  .|.|||.  || |..    . ..|   ||.|.||....|..|||. |||.| . | ... ..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

TETKFLIAEAALAIHHVHLQ-GFIHRDIKPDNLLLTKDGHVRLIDFGLS
 ...| .|.  ||. . | .   | ||.||.|.|| .||||...|||||
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLS
Kinase 93440.m00483.AA ROCK 112-264 44 2.8e-50 169.32 In-house 1-152 (263) Show / Hide 
Range on Protein: 112-264
Range on HMM: 1-152/263
Sequence Identity: 44% (68 aa)

FEKIQIIGRGSFGEVWLVKDKTDQHVYAMKVLKKRILIQRNQILNTIVEKDFYTQYDNPWSAKLYYSFQDQNHLYLIMEFLPGGDLMNLLIHRNILTETE
|. |..|||| |||| ||..|. ..|||||.| |  .|.|        |.|       .|  .|.| |||. .||..|...|||||.||.   ..  |  
FHMIKVIGRGAFGEVQLVRHKSSKKVYAMKMLSKFEMIKRSDSAFFWEERDIMAHANSEWIVQLHYAFQDDRYLYMVMDYMPGGDLVNLMSNYDV-PEKW

TKFLIAEAALAIHHVHLQGFIHRDIKPDNLLLTKDGHVRLIDFGLSTKINRFG
..|  .|  ||.  .|  ||||||.||||.|| | ||..| |||   |.|. |
ARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADFGTCMKMNKNG
Kinase 93440.m00483.AA DMPK 300-398 45 4.3e-50 121.45 In-house 160-270 (270) Show / Hide 
Range on Protein: 300-398
Range on HMM: 160-270/270
Sequence Identity: 45% (50 aa)

SAVGTTDYIAPEVL--MKKS----YGPNADFWSLGAIMFEMLYGYAPFMSSNPQLTANKIIHF-EESLIFPPTPV--VSKEAIALMRGLLTDSENRMT--
.|||| |||.||||  |       |||  |.||.| .|.|||||  ||   .   | .|| .. ...| ||. |   ||.||  | . ||.|.|.|.   
VAVGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRN

-FEEIKQHPFF
 .|..|.||||
GYEDFKCHPFF
Kinase 93440.m00483.AA MAST 302-398 37 1.6e-32 96.17 In-house 229-337 (337) Show / Hide 
Range on Protein: 302-398
Range on HMM: 229-337/337
Sequence Identity: 37% (41 aa)

VGTTDYIAPEVLMKKS-YGPNADFWSLGAIMFEMLYGYAPFMSSNPQL-TANKIIHFEESLIFPPT------PVVSKEAIALMRGLLT-DSENRMTFE--
.|| |||||||. ... ||. .| ||.| ||.| | |. ||  ..|.  . ..||. .. . .|..        .|.||. |.. ||. .   |  .   
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGA

-EIKQHPFF
 ||||||||
DEIKQHPFF
Kinase 93440.m00483.AA MAST 302-398 34 7.4e-29 89.9 In-house 225-334 (334) Show / Hide 
Range on Protein: 302-398
Range on HMM: 225-334/334
Sequence Identity: 34% (38 aa)

VGTTDYIAPEVLMKKS-YGPNADFWSLGAIMFEMLYGYAPFMSSNPQLTANKIIHFE-ESLIFPPT------PVVSKEAIALMRGLLTD-SENRMTFE--
.|| |||||||. ... .|.  | ||.| ||.| | |. ||  ..|... ..|.. .     .|..         |.||. |.. ||.   . | ..   
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG

--EIKQHPFF
  |.||||||
ADEVKQHPFF
Kinase 93440.m00483.AA ROCK 301-398 42 1e-25 84.34 In-house 159-263 (263) Show / Hide 
Range on Protein: 301-398
Range on HMM: 159-263/263
Sequence Identity: 42% (45 aa)

AVGTTDYIAPEVL----MKKSYGPNADFWSLGAIMFEMLYGYAPFMSSNPQLTANKIIHFEESLIFPPTPVVSKEAIALMRGLLTDSENRM---TFEEIK
|||| |||.||||        ||   |.|| |  ..||| |  ||       |  ||.   .|| ||. . .||.| .|..  ||| |.|.     ..||
AVGTPDYISPEVLKSQGQDGEYGRECDWWSVGVFIYEMLVGDTPFYADSLVGTYSKIMDHKNSLKFPDDVEISKQAKDLICKFLTDREQRLGRNGVDDIK

QHPFF
||.||
QHKFF
Kinase 93440.m00483.AA AktR 302-398 31 1.8e-20 74.31 In-house 165-268 (268) Show / Hide 
Range on Protein: 302-398
Range on HMM: 165-268/268
Sequence Identity: 31% (33 aa)

VGTTDYIAPEVLMK-KSYGPNADFWSLGAIMFEMLYGYAPFMSSNPQLTANKIIHFEESLIFPPTPVVSKEAIALMR-GLLTDSEN------RMTFEEIK
.||  |.|||...| | .. ..|.|..|.  .||..|. || ..| .    ||.  .  . ||... .|...  |   .|| .  |      ....||||
CGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIK

QHPFF
 ||.|
SHPWF
Kinase 93440.m00483.AA Akt 303-398 33 9.8e-20 59.69 In-house 164-264 (264) Show / Hide 
Range on Protein: 303-398
Range on HMM: 164-264/264
Sequence Identity: 33% (35 aa)

GTTDYIAPEVLMKKSYGPNADFWS-LGAIMFEMLYGYAPFMSSNPQLTANKIIHFEESLIFPPTPVVSKEAIALMRGLLT-DSENRM-----TFEEIKQH
||  |.|||.| .. ..  .|.|. ||..|.||..|  || . . .    ||  ... . ||.....|.|.  | .|||. | ..|      . .|||.|
GTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKI--KNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRH

PFF
|.|
PWF
Kinase 93440.m00483.AA TyrKc 112-398 22 2.8e-11 -40.23 SMART 1-280 (280) Show / Hide 
Range on Protein: 112-398
Range on HMM: 1-280/280
Sequence Identity: 22% (72 aa)

FEKIQIIGRGSFGEVWLVKDKTDQHVYAMKVLKKRILIQRNQILNTIVEKDFY------TQY--DNPWSAKLYYSFQDQ-------NHLYLIMEFLPGGD
 ......|.| ||||.. . |  . | | |.||.              ..||.      ...  ..|   .||    .|         |...||. |.||
ITLGKKLGEGAFGEVYKGTWK--IQV-AVKMLKEDA------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD

LMNLL-IHRNILTETETKFLIAEAALAIHHVHLQGFIHRDIKPDNLLLTKDGHVRLIDFGLSTKINRF---GDPMVKVIDLITDAFHECAGINVEHHKHQ
| . |  ||. |.  .       .|    . | ...||||.   | |......|.  ||||| .|      |                           .
LKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-------------------------ESK

KYNRF----VCSAVGTTDYIAPEVLMKKSYGPNADFWSLGAIMFEML-YGYAPFMS---SNPQLTANKIIHFEESLIFPPTPVV---------SKEAIAL
.| |      . ..      |||..... . .  | || |  |.|.. ||  |          ...  .|.. ..   .| |           ..|   .
DYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQI

MRGLLTD-SENRMTFEEIKQHPFF
|.       |.| ||.||  | .|
MKQCWHEDPEDRPTFSEI--HECF
Kinase 93440.m00483.AA Pkinase 112-146 37 1.3e-10 38.64 Pfam 1-35 (293) Show / Hide 
Range on Protein: 112-146
Range on HMM: 1-35/293
Sequence Identity: 37% (13 aa)

FEKIQIIGRGSFGEVWLVKDKTDQHVYAMKVLKKR
......||.||||.|.. ..| .....|.|..|||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR
Kinase 93440.m00483.AA Pkinase_Tyr 183-257 30 8e-06 20.37 Pfam 80-158 (270) Show / Hide 
Range on Protein: 183-257
Range on HMM: 80-158/270
Sequence Identity: 30% (24 aa)

NHLYLIMEFLPGGDLMNLLIH----RNILTETETKFLIAEAALAIHHVHLQGFIHRDIKPDNLLLTKDGHVRLIDFGLS
|..|..||. |.||| . |      .. ||  .     .. | .  . . ...||||.   | |.|....|.  ||||.
NQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 93440.m00483.AA Pkinase_Tyr 112-128 35 0.006202 10.56 Pfam 1-17 (270) Show / Hide 
Range on Protein: 112-128
Range on HMM: 1-17/270
Sequence Identity: 35% (6 aa)

FEKIQIIGRGSFGEVWL
 .... .|.|.||||..
ITFGKKLGEGAFGEVYK