100413.m00010

Species: T.vaginalis
Alias: 100413.m00010, TvagK0357
External Links:
Annotation:

Classification

Group: AGC
Family: NDR
Subfamily: NDR-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
100413.m00010.AA Protein None 448 None Fasta, JSON
100413.m00010.kin_dom Protein Kinase Domain None 281 None Fasta, JSON

Protein domain

Protein domains of 100413.m00010.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 100413.m00010.AA AGC 96-376 28 3.5e-133 346.39 In-house 1-395 (395) Show / Hide
Range on Protein: 96-376
Range on HMM: 1-395/395
Sequence Identity: 28% (117 aa)

FERIKLIGRGGFGEVWLVKDN------EDRNFYALKVLRKAD-IIMSE--QIQNVRTE------------RDILAHSD----------NPWFTY-LNCSF
|| .|.||.|.||.|.||...          .||.|||.|.. |.. .  ..... ||            |.||.. .          .|. .  | .||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDEER--LYLVLEYVC---------GG-DLMNALI---KKGVFDNDTAKFFIAE-------MTLAVHSVHE-LHFLHRD-LKPDNVLITESGHIKLTDFG
||...  ||.|.||..         || .|.  |    |.|.|| ..|.|..||       ..||... |. ... ||| |||.|.|..| |||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSK------------------NYQENDTRFQKLNDEIIELISGRPLDRPFHDR---------------GTEIG--TCSYTAPEILIGKPPTTLSDFWS--
|.|                  ..  | .  | .. .  .  . . . .  ...                |  |  |  | |||||     .   | ||  
LCKEGMNDGEKGQQSQSNMKFHW-HNKKY-Q-KS-NMDT-NK-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFG

LGVILYEMLYGFVPFMGQTSR----------ETALRII------AWKRCLVYP---QIEG-HPVSPLAVDLLQHLLC-DPEDRYG----------FEQII
||...||||.|  || |..            |.  .|.       ||  .  |   |...   .|| |.||...||| |||.| |          .|.| 
LGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIK

VHPFF
 ||.|
NHPWF

Kinase 100413.m00010.AA NDR 96-376 34 5.5e-124 384.49 In-house 1-350 (350) Show / Hide
Range on Protein: 96-376
Range on HMM: 1-350/350
Sequence Identity: 34% (122 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVRTERDILAHSD--NPWFTYLNCSFQDEERLYLVLEYVCGGDLMN---ALIKKGV
|| ||.||.|.|||||||. .. ...||.|..||..... .|. .||.||||.| .|  |||.. | .||||.  |||| ||..|||.|     |.|...
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

FDNDTAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHIKLTDFGLSKN----------------------YQENDTRFQKLNDEIIELISGRPLD
|. | |.| ||||..|..|||.. . |||.|||| ||   ||||||||||...                       ......... ..|. .  . .. .
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN

RPFHDRGT--------------------------------EIGTCSYTAPEILIG-KPPTTLSDFWSLGVILYEMLYGFVPFMGQTSRETALRIIAWKRC
. . ....                                 .||  |.|||.. . .  . . |.||||.|.|||| |. || . | .||  .|. || .
SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT

LVYP--QIE-GHPVSPLAVDLLQHLLC-DPEDRYG-----FEQIIVHPFF
.  |  ...   ..|| |.||.. |.| ||. | |     ...|  ||||
WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF

Kinase 100413.m00010.AA DMPK 96-239 44 1.2e-84 208.82 In-house 1-145 (270) Show / Hide
Range on Protein: 96-239
Range on HMM: 1-145/270
Sequence Identity: 44% (64 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVRTERDILAHSDNPWFTYLNCSFQDEERLYLVLEYVCGGDLMNALIKKG-VFDND
|| .|.|||| |||| .|.  . .  || |.. |.. .  ..   .. ||||..|.. .| | | . ||||. ||.| || .|||| . . . . ... |
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

TAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHIKLTDFG
 |.| .|||.||.||.|.... ||| ||||.|.  .||||| |||
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFG

Kinase 100413.m00010.AA S_TKc 96-376 28 3e-84 287.1 SMART 1-231 (231) Show / Hide
Range on Protein: 96-376
Range on HMM: 1-231/231
Sequence Identity: 28% (84 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVRTERDILAHSDNPWFTYLNCSFQDEERLYLVLEYVCG--GDLMNALIKKGV---
.| ...||.|.||.|........   .|.|...          ...| |..|| . . |.   |  .||| ..||.|.||. |  |||.  . |.|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FDNDTAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHIKLTDFGLSKNYQENDTRFQKLNDEIIELISGRPLDRPFHDRGTEIGTCSYTAPE
   |.  .|.|..... .|.   |.....||||||.|.|..|  |||..||||.. .                               | .||  | |||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------TTFCGTPWYMAPE

ILIGKPPTT-LSDFWSLGVILYEMLYGFVPFMGQTSRETALRIIAWKRCLVYPQIEGHPVSPLAVDLLQHLLC-DPEDRYGFEQIIV-------HPFF
.|   . ..  .| ||.|.||||||.|  ||      .. ...|                || | |.....|. |||.|..  ..         ||.|
VL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 100413.m00010.AA RSK 99-376 34 6.7e-71 241.85 In-house 1-278 (278) Show / Hide
Range on Protein: 99-376
Range on HMM: 1-278/278
Sequence Identity: 34% (104 aa)

IKLIGRGGFGEVWLVKDN---EDRNFYALKVLRKADIIMSEQ-IQNVRTERDILAHSD-NPWFTYLNCSFQDEERLYLVLEYVCGGDLMNALIKKGV---
.|. |.||.|.| |..       .  || |||.|| |. ..  .  ..|||.||...   |    |. .||.|. |||..||. ||.|   | |..    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FDNDTAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITE---SGHIKLTDFGLSKN-YQENDTRFQKLNDEIIELISGRPLDRPFHDRGTEIGTCSYTAP
|. |.|.| .|| .|||   |.... ||||||.|.| ..   .|||||||||..|    ..  . ..                        ..|  | ||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMT-----------------------FCYTIEYMAP

EILI---GKP-PTTLSDFWSLGVILYEMLYGFVPFMG---QTSRETALRIIAWKRCLVYP--QIEGHPVSPLAVDLLQHLLC-DPEDRYG-----FEQII
|.|    ..   .   | |||||..|||| |..|| |   ... |.  ||   |  |  |  |     .|. | ||....|. ||..|.|      |.| 
EMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQY----LSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIK

VHPFF
 ||.|
QHPWF

Kinase 100413.m00010.AA Ciliate-E2 96-376 24 4.3e-67 229.2 In-house 1-365 (365) Show / Hide
Range on Protein: 96-376
Range on HMM: 1-365/365
Sequence Identity: 24% (93 aa)

FERIKLIGRGGFGEVWLVKDNEDRN-----------------------FYALKVLRKADIIMSEQIQNVR----------TERDILAHSDNPWFTYLNCS
.. ||.||.|.|| |...|. ....                       .||.|...| .|.. .|....            |. || . ..|    .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--DEERLYLVLEYVCGGDLMNALIKK-----------GVFDNDTAKFFIAEMTL---------------AVHSVHELH-FLHRDLKPDNVLITESGHI
||  |.. .|||.||. ||||.  ....           . |.   .|..... .                |... |. .  .|||.||.|.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGLSKNYQENDTRFQKLNDEIIELISGR-PLDRPFHDRGTEI-----------GTCSYTAPEILIGKP---------PTTLSDFWSLGVILYEMLY
|..||||||.|...  . .. . .  ...  .   .| . . .  .           ||  | ||||| ||.          .. .|.|||||||||||.
KIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMD--QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GFVPFMGQTSRETALRIIAWKRCLVYPQIE---------------GHPVSPLAVDLLQH-----LLCDPEDRYG-FEQIIVHPFF
|  ||           ..  | | .  . .                . .|. . ||..      | .||| |.. .|||. ||.|
GKPPF-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 100413.m00010.AA MAST 96-242 46 3.6e-64 205.62 In-house 1-147 (334) Show / Hide
Range on Protein: 96-242
Range on HMM: 1-147/334
Sequence Identity: 46% (68 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVRTERDILAHSDNPWFTYLNCSFQDEERLYLVLEYVCGGDLMNALIKKGVFDNDT
|| ||.|..|..| |.||| .. . ..|.||..|.| |   ....|..||.||| ..||.   . .||| .. |..|.||. |||.   |   | || ..
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

AKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHIKLTDFGLSK
||. |||. |..   |.    ||||||||.||. .||||||||||||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSK

Kinase 100413.m00010.AA MAST 96-242 43 2.6e-63 191.99 In-house 1-150 (337) Show / Hide
Range on Protein: 96-242
Range on HMM: 1-150/337
Sequence Identity: 43% (65 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVRTERDILAHSDNPWFTYLNCSFQD--EERLYLVLEYVCGGDLMNALIKKG-VFD
|| ||.|..|..| |.|||  . . ..|.||... |.|   |...|. ||.||.  .||.   . .|||   .. |..|.||. |||    |   |  ..
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

NDTAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHIKLTDFGLSK
 . ||. |||  |..   |.    ||||||||.||.  ||||||||||||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSK

Kinase 100413.m00010.AA Pkinase 96-376 26 3.9e-63 220.86 Pfam 1-293 (293) Show / Hide
Range on Protein: 96-376
Range on HMM: 1-293/293
Sequence Identity: 26% (84 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVR-TERDILAHSDNPWFTYLNCSFQDEERLYLVLEYVCGG----DLMNALI--KK
..... ||.|.||.|.. ..  ..  .|.|...| .. ........| .|  |... . |    | ..|.|. ..|.|.||. ||    ||.  .   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GVF--DNDTAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHI----KLTDFGLSKNYQENDTRFQKLNDEIIELISGRPLDRPFHDRGTEIGTCS
|.|  . ...||.. ..  ..   |.  ..||||||.|.|| . |||    |..||||.| ..                        . .   |  ||  
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------------------Y-NNS-MTTFCGTPW

YTAPEILI-GKPPTTLSDFWSLGVILYEMLYGFVPFMGQ---TSRETALRIIAWKRC--LVYPQIEGHPVS-----------------PLAVDLLQHLLC
| |||..  |.. .. .| ||.|.|||||| |  || |.    .  . . .|. ...  | ..  . ...|                 . . |..  .||
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC

-DPEDRYGFEQIIVHPFF
 ||..|...|||  ||.|
KDPKKRPTAEQILQHPWF

Kinase 100413.m00010.AA AktR 96-248 37 3.5e-54 186.33 In-house 1-158 (268) Show / Hide
Range on Protein: 96-248
Range on HMM: 1-158/268
Sequence Identity: 37% (60 aa)

FERIKLIGRGGFGEVWLVKDN-EDRNFYALKVLRKADIIMSEQIQNVRTERDILA-HSDNPWFTYLNCSFQDEERLYLVLEYVCGGDLMNALIKKGVFDN
|...|..|.|.||.| ||... ..  .||.|...| .||  .|.. ..|||.|.. ....| .  |  .||..| |....||..||.| . | ||. |..
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DTAKFFIAEMTLAVHSVHEL-HFLHRDLKPDNVLITESGHIKLTDFGLSK--NYQEND
..|.|..|.. ||.   |.  .   |||||.| |. | ||.|.|||||||  .  ..|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYD

Kinase 100413.m00010.AA CRIK 96-239 44 7.5e-54 169.88 In-house 1-145 (272) Show / Hide
Range on Protein: 96-239
Range on HMM: 1-145/272
Sequence Identity: 44% (64 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVRTERDILAHSDNPWFTYLNCSFQDEERLYLVLEYVCGGDLMNALIKKG-VFDND
||   |||.| ||.| .|        || ||..|. .  .||.  .  ||||.. .  || . |   |||.. |||. ||  ||||   .   . .|| .
FEVKDLIGCGHFGQVQVVREKQTNDIYAMKVMHKKVVLAQEQVSFFEEERDIMSRRNSPWLPQLQYAFQDNDNLYLMMEYHPGGDLLSLMNRHDDQFDEN

TAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHIKLTDFG
 |.|. || ..||||.||  . ||| ||.|.||   ||||| |||
MARFYLAELIVAVHSLHEMGYVHRDIKPENILIDRTGHIKLADFG

Kinase 100413.m00010.AA GEK 96-239 48 9.8e-53 175.16 In-house 1-145 (269) Show / Hide
Range on Protein: 96-239
Range on HMM: 1-145/269
Sequence Identity: 48% (71 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVRTERDILAHSDNPWFTYLNCSFQDEERLYLVLEYVCGGDLMNALIK-KGVFDND
|| .|.|||| ||||  ||  .  . ||.|.| | ...    .   | |||.| . |. | | |   ||||. ||||..| .||||.  | | .    .|
FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED

TAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHIKLTDFG
 |.|.|||| .|..|||.||. |||.||||||. . |||.| |||
MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFG

Kinase 100413.m00010.AA DMPK 299-376 43 1e-33 80.03 In-house 189-270 (270) Show / Hide
Range on Protein: 299-376
Range on HMM: 189-270/270
Sequence Identity: 43% (36 aa)

DFWSLGVILYEMLYGFVPFMGQTSRETALRIIAW-KRCLVYPQIEGHPVSPLAVDLLQHLLCDPEDRYG---FEQIIVHPFF
|.||.||..||||||  ||   .. ||   |    |..|  |. . . ||. | ||.. ||||.|.| |   .|..  ||||
DWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGYEDFKCHPFF

Kinase 100413.m00010.AA CRIK 299-376 38 1.8e-24 74.63 In-house 191-272 (272) Show / Hide
Range on Protein: 299-376
Range on HMM: 191-272/272
Sequence Identity: 38% (32 aa)

DFWSLGVILYEMLYGFVPFMGQTSRETALRIIA------WKRCLVYPQIEGHPVSPLAVDLLQHLLCDPEDRYGFEQIIVHPFF
|.||.|.| ||| .|  ||   .. .|   |.        .| | .|     .||| . ||.| |||..  | ..||.  ||||
DWWSMGIIAYEMMCGKTPFHEDNMHRTYSNIMNHCEESHFQRFLSFP--DDPKVSPNYRDLIQSLLCNQSKRLKYEQLCCHPFF

Kinase 100413.m00010.AA MAST 278-376 36 4.3e-21 60.61 In-house 229-337 (337) Show / Hide
Range on Protein: 278-376
Range on HMM: 229-337/337
Sequence Identity: 36% (40 aa)

IGTCSYTAPEILIGKP-PTTLSDFWSLGVILYEMLYGFVPFMGQTSRE-TALRIIAWKRCLVYPQI----EGHPVSPLAVDLLQHLL-CDPEDRYGFE--
.||  | |||.. |..      | ||.|.|.|| | | .|| | |  | .   ||  .| . .| .    .. ..|| | || . ||  .| .| |.   
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGA

-QIIVHPFF
 .|  ||||
DEIKQHPFF

Kinase 100413.m00010.AA GEK 299-376 41 4.5e-19 60.28 In-house 188-269 (269) Show / Hide
Range on Protein: 299-376
Range on HMM: 188-269/269
Sequence Identity: 41% (34 aa)

DFWSLGVILYEMLYGFVPFMGQTSRETALRIIAWKRCLVYPQIEG-HPVSPLAVDLLQHLLCDPEDRY---GFEQIIVHPFF
|.|||||..||||||  ||  .   ||  .|. .| .. .|. |  . ||  | ||...|.| .| |    | .    ||||
DWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQDFKKHPFF

Kinase 100413.m00010.AA MAST 278-376 33 6e-19 57.41 In-house 225-334 (334) Show / Hide
Range on Protein: 278-376
Range on HMM: 225-334/334
Sequence Identity: 33% (37 aa)

IGTCSYTAPEILIGKP-PTTLSDFWSLGVILYEMLYGFVPFMGQTSRETALRIIAWKRC-LVYPQI----EGHPVSPLAVDLLQHLL-CDPEDRYGFE--
.||  | |||.. |..     .| ||.|.|.|| | | .|| . |  |.   |.  ..    .|      ..   || | || . || .||..| |.   
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG

--QIIVHPFF
  ..  ||||
ADEVKQHPFF

Kinase 100413.m00010.AA AktR 279-376 31 1.5e-13 48.78 In-house 166-268 (268) Show / Hide
Range on Protein: 279-376
Range on HMM: 166-268/268
Sequence Identity: 31% (33 aa)

GTCSYTAPEILIG-KPPTTLSDFWSLGVILYEMLYGFVPFMGQTSRETALRIIAWKRCLVYPQIEGHPVSPLAVDLLQ-HLLC-DPEDRYG-----FEQI
||  | |||..   |. .  .|.|..|. .|||..|  ||  . .... .  |  |.  .....   ..|. . ||.|  ||| .|. | |     .|.|
GTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHK-NQNQMFQKIKIKQ-QNKFPYP-SYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEI

IVHPFF
  ||.|
KSHPWF

Kinase 100413.m00010.AA TyrKc 96-376 23 1.3e-12 -18.56 SMART 1-280 (280) Show / Hide
Range on Protein: 96-376
Range on HMM: 1-280/280
Sequence Identity: 23% (71 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVRTERDILAHS--DNPW-FTYLNCSFQDE------ERLYLVLEYVCGGDLMNALI
 . .| .|.| ||||.. . .      | |.|..        ..  . |  |. .   ..|     . .  |..      | |..|.||...||| . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KKGV-FDNDTAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHIKLTDFGLSKNYQENDTRFQKLNDEIIELISGRPLD--RPFHDRGTEIGTCSY
|..  . ...   |           |. .. ||||   |.|..| ...| .|||||..  . |..    ... .   ...  .   |             
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPIR----------W

TAPEILIGKPPTTLSDFWSLGVILYEML-YGFVPFMG-----QTSRETALRIIAWKRCLVYPQIEGHPVSPL----AVDLLQHLLC-----DPEDRYGFE
.||| .  .  || || || || ..|.. ||  |  |      . .|   .. . .|    | ..     |.    . | .  .       |||||  |.
MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-----PMSFVCCPDEMYQIMKQCWHEDPEDRPTFS

QIIVHPFF
.|  | .|
EI--HECF

Kinase 100413.m00010.AA Pkinase_C 394-432 38 3e-06 25.15 Pfam 1-41 (46) Show / Hide
Range on Protein: 394-432
Range on HMM: 1-41/46
Sequence Identity: 38% (16 aa)

VIKSPTDTSHFDEIEPSEQPLAAS---IPLANISQFAFLGFT
 .|||||||.||. . .| |   .     . .. | .| |||
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFT

Kinase 100413.m00010.AA Pkinase_Tyr 211-249 35 5e-06 20.98 Pfam 128-166 (270) Show / Hide
Range on Protein: 211-249
Range on HMM: 128-166/270
Sequence Identity: 35% (14 aa)

HELHFLHRDLKPDNVLITESGHIKLTDFGLSKNYQENDT
.. .. ||||   |.|.||....| .||||..  .. |.
ESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDY

Kinase 100413.m00010.AA S_TK_X 377-435 31 2.6e-05 22.34 SMART 1-79 (79) Show / Hide
Range on Protein: 377-435
Range on HMM: 1-79/79
Sequence Identity: 31% (25 aa)

QGFDFDNPFS----NSPPMVPVIK----SPTDTSHFDEIEPSEQPLAASI--PLANISQFA----------FLGFTIKP
 |.|.|. ..      || .| ||    |||||| ||. ...|.| .  .  || |...            |.||| . 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF

Kinase 100413.m00010.AA Pkinase_Tyr 96-112 41 0.158838 5.79 Pfam 1-17 (270) Show / Hide
Range on Protein: 96-112
Range on HMM: 1-17/270
Sequence Identity: 41% (7 aa)

FERIKLIGRGGFGEVWL
 . .| .|.| ||||..
ITFGKKLGEGAFGEVYK

Kinase 100413.m00010.AA Pkinase_Tyr 165-181 42 0.235618 5.21 Pfam 76-94 (270) Show / Hide
Range on Protein: 165-181
Range on HMM: 76-94/270
Sequence Identity: 42% (8 aa)

DEER--LYLVLEYVCGGDL
..|   .|.|.||...|||
QGEPNQIYIVMEYMPHGDL

Kinase 100413.m00010.AA Pkinase_Tyr 295-329 37 1.023224 3.05 Pfam 192-228 (270) Show / Hide
Range on Protein: 295-329
Range on HMM: 192-228/270
Sequence Identity: 37% (14 aa)

TTLSDFWSLGVILYEMLY-GFVP-FMGQTSRETALRI
|| || || || ..|..  |  | . | .  |   .|
TTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI

Kinase 100413.m00010.AA Pkinase_C 376-385 50 23.726804 1.1 Pfam 37-46 (46) Show / Hide
Range on Protein: 376-385
Range on HMM: 37-46/46
Sequence Identity: 50% (5 aa)

FQGFDFDNPF
|.|| . ||.
FRGFTYVNPD