90492.m00241

Species: T.vaginalis
Alias: TvagK0408, 90492.m00241
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
90492.m00241.AA Protein None 435 None Fasta, JSON
90492.m00241.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 90492.m00241.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 90492.m00241.AA PH 5-98 23 5e-07 27.98 Pfam 1-92 (92) Show / Hide
Range on Protein: 5-98
Range on HMM: 1-92/92
Sequence Identity: 23% (23 aa)

GSTGGWLQKRGKLGFWSPKFCKLVGSQLVISKSEKVNNVEFLIEITPDTKIDIVKDPK---KHRFSIQDANGEVSVFEARNNDEMMSWILLLRSITF
    ||| |.||.. | . .. | ...|.. |..|    . .  . |  .....|.|.   .| | |   .... .|.| . .|| .|.  ..|.  
VIKEGWLHKKGKRKSWKKRWFVLFNNCLYYYKDDK----YRPKGSIPLSDCQVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR

PH 90492.m00241.AA PH 5-100 16 0.000124 22.64 SMART 1-82 (82) Show / Hide
Range on Protein: 5-100
Range on HMM: 1-82/82
Sequence Identity: 16% (16 aa)

GSTGGWLQKRGKLGFWSPKFCKLVGSQLVISKSEKVNNVEFLIEITPDTKIDIVKDPKKHRFSIQDANGEVSVFEARNNDEMMSWILLLRSITFSN
    ||| |.. .  | .... | ...|.. |..        | ..   ...  .      | |   .. . .| ... .|| .|.  ... . .|
VIKEGWLYKKS-K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDC-TVRE-P-----CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN

Kinase 90492.m00241.AA AGC 108-359 30 3.3e-148 386.16 In-house 1-395 (395) Show / Hide
Range on Protein: 108-359
Range on HMM: 1-395/395
Sequence Identity: 30% (120 aa)

FEVLSVIGRGFYGKVLLVKCK------RTGELFAIKSIR---KSILIEQNKIRIVLSE------------RNIMVKSH----------HPFIVQ-LKFAF
||.| |||.| .||| ||. |       ||...|.| ..   | .....|... ...|            |||..| .          |||||. |...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTQSK--FYLGLEYVP---------GG-ELFTHIY---RDGFLQPREYQLVIAQ-------VALALQYLHS-IGIIYRD-MKPENILIDADGYVKLTDFG
|....   |. .||.|         || |||.|..   . | .   . .  .|.       ..|||.||||  |||.|| .||||||.|.||..||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSRDITIDE---------------------------------------------------SASTFCG--TPEYIAPEVIKRLPYDTAIDWWG--LGILTY
|.  .  |.                                                    ..||||  ||||.|||..    |. | |||.  ||.| |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELIYHNPPFRSTNNQ----------QLFQKIL------KDEVPFP----------DNANPIEVNFIKGLLRKDPKKRFC----------FEEIASNEFF
|...  |||.. |.|          ..||||.      ...|.||          ..  |  ...||.|| |||.||            .||| . ..|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase 90492.m00241.AA Akt 108-359 43 1.3e-120 387.26 In-house 1-264 (264) Show / Hide
Range on Protein: 108-359
Range on HMM: 1-264/264
Sequence Identity: 43% (114 aa)

FEVLSVIGRGFYGKVLLVKCKRTGELF-AIKSIRKSILIEQNKIRIVLSERNIMVKSHHPFIVQLKFAFQTQSKFYLGLEYVPGGELFTHIYRDGFLQPR
|..| |.|.| .|||.||| | |.... |.|...|. .|..|... .. |||| ..  |||||.|...|||| | |. ..|..|||||.|..|...    
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

EYQLVIAQVALALQYLHSIGIIYRD-MKPENILIDADGYVKLTDFGLSR-D-ITIDESASTFCGTPEYIAPEVIKRLPYDTAIDWWG-LGILTYELIYHN
.    .|.. ||...||| .||||| .||||||.|.||...||||||.. . |. .. . ||||||||.|||...   .. | |||| ||...||... .
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFRSTNNQQLFQKILKDEVPFP--DNANPIEVNFIKGLLRKDPKKRFC-----FEEIASNEFF
||| . ...|.|.||.  .| ||  |.  |   ..|.||| ||||||        .|| . ..|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF

Kinase 90492.m00241.AA SGK 108-359 39 3.1e-109 338.55 In-house 1-283 (283) Show / Hide
Range on Protein: 108-359
Range on HMM: 1-283/283
Sequence Identity: 39% (111 aa)

FEVLSVIGRGFYGKVLLVKCKRT------------------GELFAIKSIRKSILI-------EQNKIRIVLSER-NIMVKSHHPFIVQLKFAFQTQSKF
|. |.||| | .|||..|| | .                  . ..|.| ..|   |         .. . ...|| .|...  |||||.|..||||. | 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLGLEYVPGGELFTHIYRDGFLQPREYQLVIAQVALALQYLHSIGIIYRDMKPENILIDADGYVKLTDFGLSR-DITIDESASTFCGTPEYIAPEVIKRL
|. ..|| |||.| |. | . .   .     |....|| ||||. ||||| |||||| |..|...||||||.  .|   .  .|||||||| ||||..  
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYDTAIDWWGLGILTYELIYHNPPFRSTNNQQLFQKILKDEVPFPDNANPIEVNFIKGLLRKDPKKRFCFE----EIASNEFF
|.| . ||| ||.. ||..|  ||| | | ||....|.. .  .| .  .     |.||| ||||||        || .  ||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF

Kinase 90492.m00241.AA AktR 108-359 42 7.79999999999e-108 364.55 In-house 1-268 (268) Show / Hide
Range on Protein: 108-359
Range on HMM: 1-268/268
Sequence Identity: 42% (115 aa)

FEVLSVIGRGFYGKVLLVKCK-RTGELFAIKSIRKSILIEQNKIRIVLSERNIMV-KSHHPFIVQLKFAFQTQSKFYLGLEYVPGGELFTHIYRDGFLQP
|.|. ..|.| .||| ||. |  .....|.|.|.|. .||.|...... |||||  .. |||||.|...|||..| .. .||.||||||.|. .....  
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

REYQLVIAQVALALQYLHSI-GIIYRDMKPENILIDADGYVKLTDFGLSR---DITIDESASTFCGTPEYIAPEVIKR-LPYDTAIDWWGLGILTYELIY
 . .  .||. |||.|||.   |||||.||||||.| ||.||.||||||.   ..  || | .|||||||.|||.|..  ... ..||| .||. ||...
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

HNPPFRSTNNQQLFQKILKDE-VPFPDNANP--IEVNFIK-GLLRKDPKKRFC-----FEEIASNEFF
 .||| . |..|.||||.. . ..||.....     ..|. .|| |.|.||       .||| |  .|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF

Kinase 90492.m00241.AA S_TKc 108-359 35 3.9e-99 336.58 SMART 1-231 (231) Show / Hide
Range on Protein: 108-359
Range on HMM: 1-231/231
Sequence Identity: 35% (95 aa)

FEVLSVIGRGFYGKVLLVKCKRTGELFAIKSIRKSILIEQNKIRIVLSERNIMVKSHHPFIVQLKFAFQTQSKFYLGLEYVPG--GELFTHIYRDGF---
.|.| .||.| .||| ... |.||...||| |.          . ...|..|. | |||.||.|. .||. ...|. .||..|  |.||..| . |    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LQPREYQLVIAQVALALQYLHSIGIIYRDMKPENILIDADGYVKLTDFGLSRDITIDESASTFCGTPEYIAPEVIKRLPYDT-AIDWWGLGILTYEL
   . . . . ...|...||.|.|| |||.|| ||||||.|    .|..||||.| .      .||||||.|.||||.   .|.. ..||| .|.. ||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

IYHNPPFRSTNNQQLFQKILKDEVPFPDNANPIEVNFIKGLLRKDPKKRFCFEEIAS-------NEFF
..  |||.  . |..|.||.           |   .||...|.|||.||    |.          ..|
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 90492.m00241.AA RSK 111-359 37 1.3e-91 310.7 In-house 1-278 (278) Show / Hide
Range on Protein: 111-359
Range on HMM: 1-278/278
Sequence Identity: 37% (105 aa)

LSVIGRGFYGKVLLVKCK---RTGELFAIKSIRKSILIEQNK-IRIVLSERNIMVKSH-HPFIVQLKFAFQTQSKFYLGLEYVPGGELFTHIYRDGF---
|.| |.| |||| |.. .    || ..| | ..|. ..  .| .| .. ||||.  .  |||||.|. ||||..|.|| .||..|||||||... ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LQPREYQLVIAQVALALQYLHSIGIIYRDMKPENILIDA---DGYVKLTDFGLSRDITID--ESASTFCGTPEYIAPEVIK---RLP-YDTAIDWWGLGI
.  .| . ..|...||...||. |||.|| |||||| |    .| .||||||...   .|  . . |||.| ||.|||..|   .   .| | ||| ||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LTYELIYHNPPFRS---TNNQQLFQKILKDE--VPFP--DNANPIEVNFIKGLLRKDPKKRFC-----FEEIASNEFF
| ||.   .|||..    | ......|.| .  ...|  ..  .   ..|...| .||.||        ||| ....|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase 90492.m00241.AA PKA 108-359 36 8.7e-90 304.6 In-house 1-263 (263) Show / Hide
Range on Protein: 108-359
Range on HMM: 1-263/263
Sequence Identity: 36% (98 aa)

FEVLSVIGRGFYGKVLLVKCKRTGELFAIKSIRKSILIEQNKIRIVLSERNIMVKSHHPFIV-QLKFAFQTQSKFYLGLEYVPGGELFTHIYRDGFLQPR
|| . ..|.| .|.| |.. | .|. .|.| ..|.  .  . .  |..|.||.   .||||| .... ||. .. |. .|||||||.|... . | .   
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

EYQLVIA-QVALALQYLHSIGIIYRDMKPENILIDADGYVKLTDFGLSRDITIDESASTFCGTPEYIAPEVIKRL-PYDTAIDWWGLGILTYELIYHNPP
. .. .| |. |||.||||  ||||| |||||||| .|..|.|||| .  ..     .| ||||||.|||.|..  ..  ..||| |||| ||.    ||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FRST--NNQQLFQKILKDEVPFPDNANPIE---VNFIKGLLRKDPKKRF-CFEE----IASNEFF
|. .  .  |...||.. .. || . .. .     .|| || .|..||. ....    |   ..|
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF

Kinase 90492.m00241.AA Pkinase 108-359 32 6.3e-87 299.9 Pfam 1-293 (293) Show / Hide
Range on Protein: 108-359
Range on HMM: 1-293/293
Sequence Identity: 32% (95 aa)

FEVLSVIGRGFYGKVLLVKCKRTGELFAIKSIRKSILIEQNKIRIVL-SERNIMVKSHHPFIVQLKFAFQTQSKFYLGLEYVPGG----ELFTHIY--RD
......||.| .|.| . . | ||...|.| |.|.   .. ... .. ||  || . .||.||.|. .|.. .. |. .||..||    .||..|   |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GFL--QPREYQLVIAQVALALQYLHSIGIIYRDMKPENILIDADGYV----KLTDFGLSRD--ITIDESASTFCGTPEYIAPEVIK-RLPYDTAIDWWGL
| .  ...| . .. |.. .|.|.|| |||.||.|||||||| .|..    |..||||..   .  .. ..||||||.|.|||||. . .|....|.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILTYELIYHNPPFRST------NNQQLFQKILKDEVPFPD---------------------NANPIEVNFIKGLLRKDPKKRFCFEEIASNEFF
|.. ||..  .|||..       . .|....|.. ...|.                      |...    |||..|.||||||  .|.|   ..|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 90492.m00241.AA PKC 108-359 35 1.5e-84 273.96 In-house 1-262 (262) Show / Hide
Range on Protein: 108-359
Range on HMM: 1-262/262
Sequence Identity: 35% (93 aa)

FEVLSVIGRGFYGKVLLVKCKRTGELFAIKSIRKSILIEQNKIRIVLSERNIMVK-SHHPFIVQLKFAFQTQSKFYLGLEYVPGGELFTHIYRDGFLQPR
|. | |.|.| .|||.|.. |.| |..||| ..| . |.   .  .. |. ..   . ||| ..|   |||... .  .||| || |  || . . .. .
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

EYQLVIAQVALALQYLHSIGIIYRDMKPENILIDADGYVKLTDFGLSRD-ITIDESASTFCGTPEYIAPEVIKRLPYDTAIDWWGLGILTYELIYHNPPF
      | ...|||.||. |||||| | .|.|.|..| .|..|||.. . .. .. .|||||||.|||||...  .|  ..||| .|.| ||.    .||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

RSTNNQQLFQKILKDEVPFPDNANPIEVNFIKGLLRKDPKKRF-C-------FEEIASNEFF
   .  .||| |..|.. .|       |. .||.. |.|.||  |       ...| .  ||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF

Kinase 90492.m00241.AA CAMK 113-359 21 1.9e-83 268.66 In-house 1-425 (425) Show / Hide
Range on Protein: 113-359
Range on HMM: 1-425/425
Sequence Identity: 21% (93 aa)

VIGRGFYGKVLLVKCKRTG------------ELFAIKSIRKSILIE-------------------------QNKIRIVLSERNIMVKSH-------HPFI
..||| .||| |.. |.|.            . .||| | |. | .                         ... . |..| .|| | .       || |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLKFAFQ------------TQSK--------FYLGL---EYVPGGEL----FTHIYRDGF---------------LQPREYQLVIAQVALALQYLHSIG
..|  ...            | ||        .|. .   ||..||||    | .| . |                .. || . .. |.. |..|.|| .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIYRDMKPENILIDADG----------------Y-VKLTDFGLSRDITI------------------------DESASTFCGTPEYIA-PEVIKR-----
|. || ||||||.| ..                . .|..|||... ..                         ..  .||||||||.| |||...     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------LPYDTAIDWWGLGILTYELIYHNPPFRST-------------NNQQLFQKILKDEVPFPDNANPI------------------------EV
          .|. ..| | .|...| .    |||..              | ..||.||.| .  ||.   ..                          
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NFIKGLLRKDPKKRFCFEEIASNEFF
..|...|..||.||.  |.. . ...
DLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 90492.m00241.AA Ciliate-E2-Unclassified 108-359 25 6.7e-82 278.39 In-house 1-352 (352) Show / Hide
Range on Protein: 108-359
Range on HMM: 1-352/352
Sequence Identity: 25% (90 aa)

FEVLSVIGRGFYGKVLLVKCKRTGELFAIKSIRKSILIEQNKIRIV---------LSERN-------------IMVKSHHPFIVQLKFAFQTQSKFYLGL
.... .||.| .||| ....| .....|.| . |.. . |..|. .         . ...             |.. . ||||| . ..||.. ..|. .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYVPGGELFTHIYRDGF-----------------LQPREYQ-----LVIAQVALALQYLHSIG-IIYRDMKPENILIDADG---YVKLTDFGLSR-----
||..||.|. .|   ..                 .. .. .       .||. ..|.|||. . ||.|| ||||||.| .|   |.|..|||.|.     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

-----------DITIDESASTFCGTPEYI----APEVIKRLPYD----TAIDWWGLGILTYELIYHNPPFRSTNNQQ----------------LFQKILK
           .|.... ..||||||.|.    ||||...  ||     ..|.|.||.. ||... ..|| ..|  |                |.|.|..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

DEVPFPDNAN-------PIEV-----NFIKGLLRKDPKKRFCFEEIASNEFF
 .. ||   .       . |.     .... .| |.|.||  ||.|    .|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 90492.m00241.AA Ciliate-E2 108-359 22 1.4e-79 270.68 In-house 1-365 (365) Show / Hide
Range on Protein: 108-359
Range on HMM: 1-365/365
Sequence Identity: 22% (87 aa)

FEVLSVIGRGFYGKVLLVKCKRTGELFA-----------------------IKSIRKSILIEQNKIRIVL----------SERNIMVKSHHPFIVQLKFA
.... .||.| .|.| ..| ......||                       .|...|. .......  ..           |.||. .  ||.|.... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--TQSKFYLGLEYVPGGELFTHIY-----------RDGFLQPREYQLV--IAQVAL---------------ALQYLHSIG-IIYRDMKPENILIDADG
||  .....|| .||. ||.|| .|.             . ... |..    ..|..                ||.|||| . ||.|| ||||||.    
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

YVKLTDFGLSRDITID--------------------------------ESASTFCGTPEYIAPEVIKRLP---------YDTAIDWWGLGILTYELIYHN
 .|..|||||.....|                                . . |.||||.| |||.... .         ||...|.| ||.. ||... .
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

PPFRSTNNQQLFQKILKDEVPFP---------DNANPIEV-----------NFIKG----LLRKDPKKRFC-FEEIASNEFF
|||        .|.|.. .. ||         ..   ...           ..||     .| |||.||.  .|.|  ...|
PPF--------QQQIKQCKIDFPCPEWQKDTQCI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 90492.m00241.AA TyrKc 108-359 25 2.9e-16 40.2 SMART 1-280 (280) Show / Hide
Range on Protein: 108-359
Range on HMM: 1-280/280
Sequence Identity: 25% (74 aa)

FEVLSVIGRGFYGKVLLVKCKRTGELFAIKSIRKSILIEQNKIRIVLSERNIMVKS--HHPFIVQLKFAFQTQ-------SKFYLGLEYVPGGELFTHI-
 . . ..|.|..|.| . . |   .  |.|.....       ..  ..| .|| |   ||| ||.|  .  .|          .. .||.|.| |  .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

YRDGFLQPREYQLVIAQVALALQYLHSIGIIYRDMKPENILIDADGYVKLTDFGLSRDITID----ESASTFC-----GTPE-----YIAPEVIKRLPYD
.. . |....      |.|   .|||| ..| ||    |.|..... || .||||||||. |    || ..       |.         |||.|.   . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

TAIDWWGLGILTYELI-YHNPPFRS-----TNNQQLFQKILKD-EVPFPDN--------ANPIEVNFIKGLLRKDPKKRFCFEEIASNEFF
|. | |  |.. .|.  |  .|         .||...... .    | |.|        . .   . .|   . ||..| .|.||   |.|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 90492.m00241.AA S_TK_X 360-420 21 1.2e-13 52.6 SMART 1-79 (79) Show / Hide
Range on Protein: 360-420
Range on HMM: 1-79/79
Sequence Identity: 21% (17 aa)

SGFNFDDVLN--KRITPPYIPTLE----DKANVKYFDNEYTSEQKMDSFVPPVMGDEAD------------VPGFSFYG
.|...|...|  |.|.||..|..     .   ...|| |.|.|. |.. ..|.. . ..             .||..  
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF

Kinase 90492.m00241.AA Pkinase_Tyr 108-260 27 4.4e-13 44.94 Pfam 1-165 (270) Show / Hide
Range on Protein: 108-260
Range on HMM: 1-165/270
Sequence Identity: 27% (45 aa)

FEVLSVIGRGFYGKVLLVKCK----RTGELFAIKSIRKSILIEQN-KIRIVLSERNIMVKS-HHPFIVQLKFAFQ-TQSK--FYLGLEYVPGGELFTHIY
 . . ..|.| .|.| . ..|     |.   |.|.. |    ... ...  ..| .|| .  ||| ||.|  .    .     |. .||.|.| | ..  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

R----DGFLQPREYQLVIAQVALALQYLHSIGIIYRDMKPENILIDADGYVKLTDFGLSRDITIDE
.    .. | . .     .|.| ...||.|...| ||    |.|.. .. || .||||.|||. |.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDD