88271.m00402

Species: T.vaginalis
Alias: 88271.m00402, TvagK0302
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
88271.m00402.AA Protein None 965 None Fasta, JSON
88271.m00402.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 88271.m00402.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 88271.m00402.AA TKL 130-377 20 6.3e-67 228.65 In-house 1-364 (364) Show / Hide
Range on Protein: 130-377
Range on HMM: 1-364/364
Sequence Identity: 20% (79 aa)

IGKGGFGQVWLANDLK--------TGKLVAIKELFAEKLVGKNL-----------------------VNFVREVVTMAKSH--NRFILPFVGFTVDKP--
||.||||.|. ..           ||| ||.| .  .    ...                        .| .|...| .|      |..|.|.  . |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YSIITEYMPNSA-LNIHLFKELNSKVPVFSGTHLTM-IAIGIIHAIRHLHSIK--------IVHRDIKAANILLDHHFL---------
            . |..||.|.   |....              |... .|..|  .. .||| .        |.|||.| .|||.| ..          
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNP

-----PKLCDFGISRICKPRKFMSDH--------------------VGTPAYMAPEILNTN----------------NYDFKVDIYSYGMLLFHMIEKRI
     .|.||||.||  .... |.|                     .|||..||||.|. .                 |. |.|.||.|..|. ..  ..
NADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR

PFSKVDVNTI----------FNDTSKGKRPTLT---------RKNSQS---IIDLMNLCWSQNPNGRPSAVKIYQMF
|... . ...            . .||.||..           ....    ...||  ||...|. |||. .| . .
PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

S_TKc 88271.m00402.AA S_TKc 124-379 26 2.4e-55 191.13 SMART 1-231 (231) Show / Hide
Range on Protein: 124-379
Range on HMM: 1-231/231
Sequence Identity: 26% (73 aa)

FIFSQLIGKGGFGQVWLANDLKTGKLVAIKELFAEKLVGKNLVNFVREVVTMAKSHNRFILPFVGFTVDKPYSIITEYMPN---SALNIHLFKELNSKVP
. . ..||||.||.|... . |||..||||..           .. ||.  . | |  .|  . .. .|. . ...||...   .     ||. . .. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGD-----LFDYIKKRGR

V-----FSGTHLTMIAIGIIHAIRHLHSIKIVHRDIKAANILLDHHFLPKLCDFGISRICKPRKFMSDHVGTPAYMAPEILNTNNYDF-KVDIYSYGMLL
      |.  |   ..  |. |. ..|| .|.|||.| .|||||.    |.||||..|.       .  .||| |||||.|    |.. |.|..| | .|
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

FHMIEKRIPFSKVDVNTIFNDTSKGKRPTLTRKNSQSIIDLMNLCWSQNPNGRPSAVKIYQ-------MFAS
. |.  . ||.  .....|.              |.. .|... |.  .|. ||.| .. |       .   
YEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Pkinase 88271.m00402.AA Pkinase 124-377 24 2.4e-54 191.68 Pfam 1-293 (293) Show / Hide
Range on Protein: 124-377
Range on HMM: 1-293/293
Sequence Identity: 24% (72 aa)

FIFSQLIGKGGFGQVWLANDLKTGKLVAIKELFAEKLVGKNLVNFVR--EVVTMAKSHNRFILPFVGFTV--DKPYSIITEYMPNS-ALNIHLFKELN--
. . . ||.|.||.|... . .|||.||.|..  ..   . ... .|  |.  |.. .  .|. . ..    |..| ...||...     . ||  .   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLY-VMDLFDYISTW

SKVPV-FSGTHLTMIAIGIIHAIRHLHSIKIVHRDIKAANILLDHHFLP----KLCDFGISRI--CKPRKFMSDHVGTPAYMAPEILN-TNNYDFKVDIY
.. .. ||  .. ...  |. .. ..|| .|.|||.| .|||.|..  .    |.||||...     .   |.. .||| |||||...  . |. |||..
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SYGMLLFHMIEKRIPFSKV------DVNTIFNDTSKGKRPTLTRKNS---------------------QSIIDLMNLCWSQNPNGRPSAVKIYQM--F
|.| .|. |. .| ||.        | . ... . .|...   . ..                     .. .|... |. ..|. ||.|  | |   |
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRI-MGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 88271.m00402.AA STE 124-378 22 4e-50 172.85 In-house 1-359 (359) Show / Hide
Range on Protein: 124-378
Range on HMM: 1-359/359
Sequence Identity: 22% (83 aa)

FIFSQLIGKGGFGQVWLANDLK---------------TGKLVAIKEL-FAEKLV--------------GKNLVNFVREVVTMAKSH--NRFILPFVGFTV
. . . ||||.||.| .| . |               ||...|||.. . ..                 ... .. .|. .| |..    .|  . |  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DKP--------YSIITEYMPNSALN---IHLF---KELNSKV---PVFSGTHLTMIAIGIIHA-IRHLHSIKIVHRDIKAANILLDHHFLPKLCDFGISR
..           |. |||..  |     | .   |.||..     .|. . .  |.  |...   .||| .|.|||||.|||||      ||||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

ICKP-----------------RKFMSDHVGTPAYMAPEILNT------NNYDFKVDIYSYGMLLFHMIEKRIPFSK-VDVNTIFNDTSK-----------
.  .                  .     |||| .||||...       . ||.|.||.| | .. .|.. . |...  .   .|. . .           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---GKRPTLTR-------------------KNSQSIIDLMNLCWSQNPNGRPSAVKIYQ---MFA
   |. |.|                     | |.. .| .|.|   .|| ||.| .  .    | 
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase 88271.m00402.AA LRRK 193-379 29 1.6e-46 160.89 In-house 128-351 (351) Show / Hide
Range on Protein: 193-379
Range on HMM: 128-351/351
Sequence Identity: 29% (65 aa)

KPYSIITEYMPNSALNIHLFKELNSKV----PVFSGTHLTMIAIGIIHAIRHLHSIK--IVHRDIKAANILL---D---------HHFLPKLCDFGISR-
.|. ...||.|. .|. .|... ...     ...| . .  ||. |  ....||| .  |.||| |  ||||   .          |   |..|||||| 
HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRM

-ICKPRKFMSDHVGTPAYMAPEILNTN---NYDFKVDIYSYGMLLFHMIEKR-IPFSKVD-------VNTIFNDTSKGKRPTLTRK-NSQ-----SIIDL
  | . .. .. ||.| .|||||.. |   .|. |||.||.||.|.. .  . .||   |        ..| .  ..| |||.    . .     .  ||
FQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDL

MNLCWSQNPNGRPSAVKIYQMFAS
...||...|. ||.. .| .   .
IQHCWQHDPKKRPHFSQIVKRLSQ

Kinase 88271.m00402.AA MLK 124-377 26 2.6e-45 155.16 In-house 1-291 (291) Show / Hide
Range on Protein: 124-377
Range on HMM: 1-291/291
Sequence Identity: 26% (78 aa)

FIFSQLIGKGGFGQVWLANDLKTG---KLVAIKELFAEK----LVG---KNLVNFVREVVTMAKSH-NRFILPFVGFTVDKPYS--IITEYMPNSALNIH
. |.. ||.|.||.||...  ..    | ||.|. .|..      .   ...  ..|..  . .   .  | .|.|   . |.   |..||.... |. .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY-N

LFKELNSKVP----------VFSGTHLTMIAIGIIHAIRHLHSIK---IVHRDIKAANILLDH------HFLPKLCDFGISR-ICKPRKFMSDHVGTPAY
. .. .||            | .  |.  .|  . ...  ||| .   |.|||.|  |||.|.      |   | ||||.|| ...  . | .  ||.|.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

MAPEIL---NTNNYDFKVDIYSYGMLLFHMIEKRIPFS-KVD-VNTIFNDTSKGKRPTLTRKNSQSIIDLMNLCWSQNPNGRPSAVKIYQMF
||||..     . |. |.|..|.|..|  |. ...|..  .|    ..  . .|.||..    . ..  ||. ||.|.|. |||   | | .
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase 88271.m00402.AA Dicty5 125-381 33 3.6e-45 153.41 In-house 2-260 (260) Show / Hide
Range on Protein: 125-381
Range on HMM: 2-260/260
Sequence Identity: 33% (88 aa)

IFSQLIGKGGFGQVWLANDLKTGKLVAIKELFAEKLVGKNLVNFVREVVTM-AKS--HNRFILPFVGFTVDKPY-SIITEYMPNSALNIHLFKELN-SKV
.| . |  |  |.|   |    |. ||||..  |  .. ... | |||  | .    |  ||  .   . .. |  ..|||  |  |   |    .    
SFHDWIASGASGRVY--NGIYKGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQ

PVFSGTHLTMIAIGIIHAIRHLHSIKIVHRDIKAANILLDHHFLPKLCDFGISRICKPRKFMSDHVGTPAYMAPEILNTNNYDFKVDIYSYGMLLFHMIE
|.  .. | | ||.|  ..|||||. |.|||.|  |.|.   .  |. |||.||    |. |  ||||...||.|. | . |. |.|.||.|  |. |. 
PIAYFQQLHM-AIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFT

KRIPFSKVDVNTIFNDTSKGKRPTLTRKNSQSIIDLMNLCWSQNPNGRPSAVKIYQMFASGQ
.  |.  .    | .   || |||.      .|  |   || | |  |||  .| ..| |  
RKEPYDNINNWNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII

Kinase 88271.m00402.AA Ciliate-E2 124-375 20 1.2e-44 151.14 In-house 1-361 (365) Show / Hide
Range on Protein: 124-375
Range on HMM: 1-361/365
Sequence Identity: 20% (77 aa)

FIFSQLIGKGGFGQVWLANDLKTGKLVAIK-----------------ELFAEKLVGKNLVNFVREVVTMA-----------------KSHNRFILPFVGF
..| ..||.|.||.|..... |..|..|||                  ..| | . || ....  .  .                  .  . .|. .. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

TV---DKPYSIITEYMPNSALNIHL-------FKELN-------SKVPVFSGTHLT-------MIAIGIIHAIRHLHSIK-IVHRDIKAANILLDHHFLP
     |. . ...||     |  ..       ..|..        ..  ..   |        ...  ||.|...||| . |.|||||  |||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLCDFGISRICKPR-----------KFMSDH----------------------VGTPAYMAPEILNTNN---------YDFKVDIYSYGMLLFHMIEKRI
|..|||.|.....            ..|  .                      .||| ||||||||  .         ||.|.||.| |..|. |. .. 
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFSKVDVNTI----FNDTSKGKRPTL--------TRKNSQSIIDLMNL----CWSQNPNGRPS-AVKIYQ
||   . .      |.   ..|. |.        . | ||. .||..     .   .|. |.. . .| .
PF--QQQIKQCKIDFPCPEWQKD-TQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN

Kinase 88271.m00402.AA CAMK 129-335 20 2.5e-42 133.72 In-house 1-352 (425) Show / Hide
Range on Protein: 129-335
Range on HMM: 1-352/425
Sequence Identity: 20% (72 aa)

LIGKGGFGQVWLANDLKTG------------KLVAIKELFAEKLV--------------------------GKNLVNFVREVVTMAKSH-------NRFI
 .|.|.||.| |. . .|.            . |||| .  .||                           .|.. |. ||.  | | .        . |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LPFVGF--------------TVDKP-------YSIIT---EYMPNSALNIHLFKELNSKVP--------------VFSGTHLTMIAIGIIHAIRHLHSIK
. .  .              | .|.       . ...   ||...  | . ||  . .. .               |.      .   |. |....|| .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDIKAANILLDHH-----------------FLPKLCDFGISRICKP------------------------RKFMSDHVGTPAYMA-PEILNTNN---
|||||.|  |||||..                 .  |..||| .....|                         . |.. .|||.||| ||.|| .    
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------YDFKVDIYSYGMLLFHMIEKRIPFSKVDVNTIF-------ND
           |..|.|. | | .|. |   . ||   . | |.       ||
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMND

Kinase 88271.m00402.AA TKL-Unique 126-377 26 3.8e-42 146.34 In-house 1-290 (290) Show / Hide
Range on Protein: 126-377
Range on HMM: 1-290/290
Sequence Identity: 26% (78 aa)

FSQLIGKGGFGQVWLANDLKTGKLVAIKELFA-EKLVGKNLVNFVREVVTMAKSH-NRFILPFVGFTVD---KPY--SIITEYMPNSALNIHLF--KELN
|. .|| ||.|||  .     |. |||| ..  |..  . . .| .|| .| | |   .|. ..|...|   .|   .|..||.| . |. .|     .|
FWNKIGEGGYGQVYKG--KWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---SKVPVFSGTHLTMIAIGIIHAIRHLHSIK--IVHRDIKAANILLDHH-----FLPKLCDFGISRICK--PRKFMSDH--------VGTPAYMAPEIL
   ..   ..      .|| |  .  .||. .  | |||.|  |.|.| .     .  |.||||.|.. .   ... . |        .|.. .||||.|
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

NT--NNYDFKVDIYSYGMLLFHMIEKRI------PFSKVDVNTIF---NDTSKGKRPTLTRKNSQSIIDLMNLCWSQNPNGRPSAVKIYQMF
.   . |. |.|.||.|. |  ...  |      |....| . ..    .. ...||..     ... ||.. || ..|  |||   |.   
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase 88271.m00402.AA Ciliate-E2-Unclassified 124-375 19 1.5e-38 131.36 In-house 1-348 (352) Show / Hide
Range on Protein: 124-375
Range on HMM: 1-348/352
Sequence Identity: 19% (70 aa)

FIFSQLIGKGGFGQVWLANDLKTGKLVAIKELFAEKLVGKNLVNFV----REVVTMAKSHNRFILP---------------------FVGFTVDKPYSII
... . ||.||||.|... . |.... |.|..   . . .......    .|  .| .  . ..                       |  |. ..   |.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

TEYMPNSALNIHL----------------------FKELNSKVPVFSGTHLT---MIAIGIIHAIRHLHSIK-IVHRDIKAANILLDHH---FLPKLCDF
.||...  |  ..                      | | ..|.             ..  |. .. .||. . |.|||||  |||.|     . .|..||
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKY--------KKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDF

GISRICK----------------PRKFMSDHVGTPAYM----APEILNTNNYD----FKVDIYSYGMLLFHMIEKRIPFSKVDVNT--------------
|||.  .                ... |.. .||| ||    |||.|  .|||    .|.||.| |..|. |.  . ||.  . .               
GISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYR

--IFNDTSKG---KRPTLT----RKNSQSIIDLMN----LCWSQNPNGRPSAVKIYQ
  ....  ..   ...        . |.. .|. |     .   ||| |... .| .
KQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN

Kinase 88271.m00402.AA CAMKL 234-324 41 6.9e-33 102.17 In-house 136-236 (297) Show / Hide
Range on Protein: 234-324
Range on HMM: 136-236/297
Sequence Identity: 41% (42 aa)

IIHAIRHLHSIKIVHRDIKAANILLDHHF--LPKLCDFGISRICKP-----RKFMSDHVGTPAYMAPEILNT--NNYD-FKVDIYSYGMLLFHMIEKRIP
|..|. ..|| .|||||||. |||||..     |..||| | ...|      .... . |.|.||||||..     || .|||| | | .|. |.  . |
IVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLP

F
|
F

Kinase 88271.m00402.AA TyrKc 124-377 22 2e-28 101.71 SMART 1-280 (280) Show / Hide
Range on Protein: 124-377
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

FIFSQLIGKGGFGQVWLANDLKTGKLVAIKELFAEKLVGKNLVNFVREVVTMAKS--HNRFILPFVGFTVD--------KPYSIITEYMPNSALNIHL-F
  . . .| | ||.|...  .|    ||.| | ...     .  | ||   | |   |.  |. ..|  ..        .|. |..||||. .|. .|  
ITLGKKLGEGAFGEVYKG-TWK--IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KELNSKVPVFSGTHLTMIAIGIIHAIRHLHSIKIVHRDIKAANILLDHHFLPKLCDFGISRICKPR---------KFMSDHVGTP-----AYMAPEILNT
.. .     ..  .|  ... |    ..||| ...|||. | |.|... .  | .||| ||  .           . .. | |.        |||| .|.
HRPK-----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

NNYDFKVDIYSYGMLLFHMIEK-RIPFSK-----VDVNTIFNDTSKGKRPTLTRK--------NSQSIIDLMNLCWSQNPNGRPSAVKIYQMF
. . .| |..|.| ... .      | .      ..   ....  .|.|.              .. . ..|  ||  .|. ||.   |.. |
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 88271.m00402.AA Pkinase_Tyr 124-273 27 9.3e-21 70.92 Pfam 1-159 (270) Show / Hide
Range on Protein: 124-273
Range on HMM: 1-159/270
Sequence Identity: 27% (44 aa)

FIFSQLIGKGGFGQVWLANDL----KTGKLVAIKELFAEKLVGKN--LVNFVREVVTMAKS-HNRFILPFVGFTV--DKP--YSIITEYMPNSALNIHLF
 .| . .|.| ||.|...       .|.  ||.| |  |.   ..  .  | ||. .| .  |.  |. ..|  .  ..|  . |..||||.  |  .| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KELNSKVPVFSGTHLTMIAIGIIHAIRHLHSIKIVHRDIKAANILLDHHFLPKLCDFGISR
|   .  . ..  .|  ... |  .  .|.|....|||. | |.|... .  | |||| .|
KHR-EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR

Kinase 88271.m00402.AA CAMKL 124-160 39 2.4e-10 29.1 In-house 1-38 (297) Show / Hide
Range on Protein: 124-160
Range on HMM: 1-38/297
Sequence Identity: 39% (15 aa)

FIFSQLIGKGGFGQVWLAND-LKTGKLVAIKELFAEKL
... . .|||.||.| || . . ||. |||| .  .|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKI

Kinase 88271.m00402.AA Pkinase_Tyr 354-377 37 0.000169 15.86 Pfam 247-270 (270) Show / Hide
Range on Protein: 354-377
Range on HMM: 247-270/270
Sequence Identity: 37% (9 aa)

DLMNLCWSQNPNGRPSAVKIYQMF
||| .|| ..|. ||.   |....
DLMKQCWHYDPEDRPTFSEIHEQL

Kinase 88271.m00402.AA Pkinase_Tyr 291-315 40 0.007401 10.3 Pfam 181-205 (270) Show / Hide
Range on Protein: 291-315
Range on HMM: 181-205/270
Sequence Identity: 40% (10 aa)

MAPEILNTNNYDFKVDIYSYGMLLF
|||| .|.. .  | |..|.| |..
MAPECINYGKFTTKSDVWSFGVLMW

Kinase 88271.m00402.AA LRRK 124-138 43 0.013384 5.0 In-house 1-16 (351) Show / Hide
Range on Protein: 124-138
Range on HMM: 1-16/351
Sequence Identity: 43% (7 aa)

FIFSQLIGKGGFG-QV
... ..||.||||  |
LKIEEQIGRGGFGTFV