Gene 89135.m00265 (T.vaginalis)
89135.m00265
Species: T.vaginalis
Alias: 89135.m00265, TvagK1008
External Links:
Annotation:
Group:
Other
Family:
Other-Unique
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 89135.m00265.AA | Protein | None | 963 | None | Fasta, JSON |
| 89135.m00265.kin_dom | Protein Kinase Domain | None | 236 | None | Fasta, JSON |
Protein domains of 89135.m00265.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| DUF3447 | 89135.m00265.AA | DUF3447 | 57-132 | 47 | 3.1e-50 | 143.75 | Pfam | 1-90 (90) | Show / Hide |
Range on Protein: 57-132 Range on HMM: 1-90/90 Sequence Identity: 47% (43 aa) FHPEITEKCLQLSFLGKNMEIRNECLKHKKPDEKCMEFAILSHKFKLVDYLKQE-HNL-EIV--------PEACV--KYCNLE--AFLFY |..|||.||||.|||| | .| |||||..||||.||..|| || ..|..| | .|. || .. |. || ||. ||. | FNSEITQKCLQFSFLGGNPDIMNECLKYQKPDEECMKYAIISHNIDFVTFLMNELYNIYEIDAKDYWDPYLDYCCDIKYNNLQNAAFFVY |
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| Kinase | 89135.m00265.AA | Ciliate-E2 | 433-517 | 21 | 1.4e-13 | 42.96 | In-house | 149-279 (365) | Show / Hide |
Range on Protein: 433-517 Range on HMM: 149-279/365 Sequence Identity: 21% (29 aa) KIFTQVYV---------------AIANLHDDK-VIHRDIKPRNILITSDLNAVLCDFSFGRQADDTSIEHC----------------------------- .|..|. |. || . .||||||| |||. ..|| . ...|| .... YIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNM ---IPGTIPYQAYENFQKRFKD---MSDDVKEKCDW | || .|.| |.... | . . .|||. FNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDI |
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| Kinase | 89135.m00265.AA | CAMKK-Unclassified | 433-474 | 26 | 5.4e-13 | 38.35 | In-house | 182-249 (392) | Show / Hide |
Range on Protein: 433-474 Range on HMM: 182-249/392 Sequence Identity: 26% (18 aa) KIFTQVYVAIANLHDDK---------------------VIHRDIKPRNILITSDLN-----AVLCDFS |.| |. .. .|. . .||||||| ||||... | ....||. KYFRQCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFG |
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| Kinase | 89135.m00265.AA | Ciliate-E2-Unclassified | 433-475 | 34 | 6.3e-13 | 41.2 | In-house | 147-193 (352) | Show / Hide |
Range on Protein: 433-475 Range on HMM: 147-193/352 Sequence Identity: 34% (16 aa) KIFTQVYVAIANLHDDK-VIHRDIKPRNILITSDL---NAVLCDFSF ..| |. ... || . .||||||| |||.... . ..||.. FYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGI |
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| Kinase | 89135.m00265.AA | CAMKK | 445-474 | 30 | 7.5e-13 | 36.68 | In-house | 192-244 (396) | Show / Hide |
Range on Protein: 445-474 Range on HMM: 192-244/396 Sequence Identity: 30% (16 aa) LH-DDK-------------------VIHRDIKPRNILITSDL---NAVLCDFS || . | .||||||| ||||... .....||. LHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFG |
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| Kinase | 89135.m00265.AA | CDKL | 437-478 | 51 | 2.7e-11 | 34.89 | In-house | 106-148 (286) | Show / Hide |
Range on Protein: 437-478 Range on HMM: 106-148/286 Sequence Identity: 51% (22 aa) QVYVAIANLHDDKVIHRDIKPRNILIT-SDLNAVLCDFSFGRQ |. ||. .| ..||||||| ||||| .. |||| | |. QILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFARM |
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| Kinase | 89135.m00265.AA | TKL | 410-473 | 17 | 2.8e-11 | 36.89 | In-house | 124-198 (364) | Show / Hide |
Range on Protein: 410-473 Range on HMM: 124-198/364 Sequence Identity: 17% (15 aa) S-LDDIISRYEKNTECPLFLSDFFKIFTQVYVAIANLHDDK--------VIHRDIKPRNILITSDLN--------------AVLCDF | |.... .. .... .. ... || .. .||||.|..|||. .... . .||| SLLHYLH------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDF |
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| Kinase | 89135.m00265.AA | AGC | 437-473 | 41 | 4e-11 | 23.51 | In-house | 161-199 (395) | Show / Hide |
Range on Protein: 437-473 Range on HMM: 161-199/395 Sequence Identity: 41% (16 aa) QVYVAIANLHD-DKVIHRD-IKPRNILITSDLNAVLCDF .. |. ||. ..|||| .|| |||...| . |.|| CIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDF |
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| Kinase | 89135.m00265.AA | Ciliate-E1 | 410-511 | 23 | 9.1e-11 | 31.71 | In-house | 82-202 (202) | Show / Hide |
Range on Protein: 410-511 Range on HMM: 82-202/202 Sequence Identity: 23% (29 aa) SLDDIIS--------RYEKNTECPLFLSDFFKIFTQVYVAIANLHDDKVIHRDIKPRNILITSDLNAVLCDFSFGR-----QADDTSIEHCIPGTIPYQA || | .. ..... . . .|. | ... ||. ..||||||| ||||... | |.|||. .. | ... ... . |.. SLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQ YE------NFQKRFKDMSDDV | | .. . .|| YNCPEQEHNKNQKINYKSDIY |
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| Kinase | 89135.m00265.AA | Aur | 432-473 | 41 | 2.6e-10 | 22.9 | In-house | 104-146 (257) | Show / Hide |
Range on Protein: 432-473 Range on HMM: 104-146/257 Sequence Identity: 41% (18 aa) FKIFTQVYVAIANLHDDKVIHRDIKPRNILIT-SDLNAVLCDF .|.. |. |. .| ..||||||| |||. .. | .||| AKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDF |
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| Kinase | 89135.m00265.AA | MSK | 434-477 | 36 | 3e-10 | 30.85 | In-house | 106-152 (277) | Show / Hide |
Range on Protein: 434-477 Range on HMM: 106-152/277 Sequence Identity: 36% (17 aa) IFTQVYVAIANLHDDKVIHRDIKPRNILITSD---LNAVLCDFSFGR |. .. .|. .|. ..||||.|| ||| ... .| || | | IMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFAR |
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| Kinase | 89135.m00265.AA | Pkinase | 433-473 | 33 | 1.4e-08 | 31.41 | Pfam | 112-156 (293) | Show / Hide |
Range on Protein: 433-473 Range on HMM: 112-156/293 Sequence Identity: 33% (15 aa) KIFTQVYVAIANLHDDKVIHRDIKPRNILITSDLNA----VLCDF ....|. ... .|. ..||||.|| |||| .. . .||| FYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDF |
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| S_TKc | 89135.m00265.AA | S_TKc | 270-632 | 13 | 1.6e-07 | -66.67 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 270-632
Range on HMM: 1-231/231
Sequence Identity: 13% (50 aa)
FQFLQEV----YSKVFSNSSSSLFLTDTNCLLRIFTDNHDVDSNGIAKLFSFSTKEVKADVFKAYKGEATGKISLTQLDHSNQLLIKKNILDNTDKYRFG
...|... ..||. . |. . . | .
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK-------------------------------------------------------------EHI
NREIRIYNKNFGFFINTVVTHGIEQLVDPDRPTAYIETSLQPF--ASLDDIISRYEK-NTECPLFLSDFFKIFTQVYVAIANLHDDKVIHRDIKPRNILI
|||.| | . . .. .| |. . . . .| |.| .. . . .|. . ... |. |.. .|. ..||||.|| |||.
RREIQILKK-----HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILL
TSDLNAVLCDFSFGRQADDTSIEHCIPGTIPYQAYENFQKRFKDMSDDVKE-KCDWHAFVTSIVKTLLTSDP-YSHVSLPRDQLQNHVCNCNPPYLLDKM
.. . .||| . || . . || | | | . |||| .. |. .|. | .. ... ....
DE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---------GYGKCKCDWWSC-GCILYEMLCGYPPFP----QMQMMFKKIG-----------
RFSRTVYEEIYKGWNRTDFDPLHLIYLMANEVTYQFELIKNGNEDELK----KYLDEECNSRCDIKTSKD-----FNSQFI
.|.| | |. . . | . . ...
-------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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