Gene 93622.m00042 (T.vaginalis)

93622.m00042

Species: T.vaginalis
Alias: 93622.m00042, TvagK0425
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
93622.m00042.AA Protein None 457 None Fasta, JSON
93622.m00042.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 93622.m00042.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93622.m00042.AA AGC 89-340 29 2.3e-150 391.84 In-house 1-395 (395) Show / Hide 
Range on Protein: 89-340
Range on HMM: 1-395/395
Sequence Identity: 29% (117 aa)

FKIIAVIGRGFYGKVMLCENK------TTHEIVAIKSIHKSR---LIQSNKVHTVIAE------------RNILTKVQ----------HPFIVS-LRFAF
|... |||.| .|||.|.. |      .| .. |.| . |..   ... |.|. ...|            ||||.|..          |||||. | ..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTASK--FYLGLEYAP---------GG-ELFFHMQ---KNGSLPLYDIKLYIAE-------ICMALHHLHS-IGIVYRD-LKPENILLDKDGYIKLTDFG
|. ..   |. .||.|         || |||.|.|   |.|...   .. |.||       |..||..|||  ||..|| |||||||||.||.|||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKDMSYA---------------------------------------------------TQTNTFCG--TSEYLAPEIVHRQPYTVAVDWWA--VGILTY
|.| .                                                       .|.||||  | ||.||||.    |. |.|||.  .|.| |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELLFGVTPFAHSN----------RARLFQNIL------EKEPTFP----------INTNPQILRFISALLTKDAKLRPN----------YDQIIQMPFF
|.|.| .|| . |          .. .||.|.      .....||           .  |.   .|. ||.|| . |.           ...| . |.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 93622.m00042.AA Akt 89-340 43 8.4e-119 381.42 In-house 1-264 (264) Show / Hide 
Range on Protein: 89-340
Range on HMM: 1-264/264
Sequence Identity: 43% (114 aa)

FKIIAVIGRGFYGKVMLCENKTTHEIV-AIKSIHKSRLIQSNKVHTVIAERNILTKVQHPFIVSLRFAFQTASKFYLGLEYAPGGELFFHMQKNGSLPLY
| .. |.|.| .|||.|.. | | ..  |.|.. |...|| |.|  ...||||| ...|||||.| ..|||. | |. ..|..|||||.|.|. .  .  
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

DIKLYIAEICMALHHLHSIGIVYRD-LKPENILLDKDGYIKLTDFGLSK-D-MSYATQTNTFCGTSEYLAPEIVHRQPYTVAVDWWA-VGILTYELLFGV
 .. |.|||  |. |||| .|.||| |||||||.||||.|.||||||.| . ...   |.||||| |||||||   . .| |||||. .|...||...| 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

TPFAHSNRARLFQNILEKEPTFP--INTNPQILRFISALLTKDAKLRPN--YD---QIIQMPFF
 || . .. ..|..|....  ||  ..  |.   .|| ||.|| |.|.   ..   .| . |.|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 93622.m00042.AA SGK 89-340 37 1.5e-112 348.99 In-house 1-283 (283) Show / Hide 
Range on Protein: 89-340
Range on HMM: 1-283/283
Sequence Identity: 37% (107 aa)

FKIIAVIGRGFYGKVMLCENKTT------------------HEIVAIKSIHKSRLI-------QSNKVHTVIAER-NILTKVQHPFIVSLRFAFQTASKF
|... ||| | .|||.. . | .                    . |.| . |   |       . ...  . ||| .|| .. |||||.|..||||. | 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLGLEYAPGGELFFHMQKNGSLPLYDIKLYIAEICMALHHLHSIGIVYRDLKPENILLDKDGYIKLTDFGLSK-DMSYATQTNTFCGTSEYLAPEIVHRQ
|. ..|. |||.|.|.|. ...|    . | |||  || .|||. |.|||||||||||| .|...||||||.| ..   . | ||||| ||||||. . |
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYTVAVDWWAVGILTYELLFGVTPFAHSNRARLFQNILEKEPTFPINTNPQILRFISALLTKDAKLRPNYD----QIIQMPFF
|.  .||||  |.. ||...|  || . |.. ...||. ..  .| .  ..    |  ||.|| | | .      .| . |||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 93622.m00042.AA AktR 89-340 40 2.1e-105 356.5 In-house 1-268 (268) Show / Hide 
Range on Protein: 89-340
Range on HMM: 1-268/268
Sequence Identity: 40% (109 aa)

FKIIAVIGRGFYGKVMLCENK-TTHEIVAIKSIHKSRLIQSNKVHTVIAERNILT-KVQHPFIVSLRFAFQTASKFYLGLEYAPGGELFFHMQKNGSLPL
|......|.| .|||.|.. | .. ...|.|.|.|. .|. |. | .| ||||.  ...||||| | ..||| .| .. .|| ||||||.| .|.. .  
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

YDIKLYIAEICMALHHLHSI-GIVYRDLKPENILLDKDGYIKLTDFGLSK---DMSYATQTNTFCGTSEYLAPEIVHR-QPYTVAVDWWAVGILTYELLF
 ... |.|.|. || .||.   |.||||||||||||.||..|.|||||||   .|.|   ...|||| ||.|||.. . .... .|||||.||. ||...
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GVTPFAHSNRARLFQNILEKE-PTFPINTNP--QILRFIS-ALLTKDAK-----LRPNYDQIIQMPFF
| .|| |.|. ..||.|..|.   ||.....  |   .|   || |. .      ... ..|   |.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 93622.m00042.AA S_TKc 89-340 35 1.8e-101 344.31 SMART 1-231 (231) Show / Hide 
Range on Protein: 89-340
Range on HMM: 1-231/231
Sequence Identity: 35% (96 aa)

FKIIAVIGRGFYGKVMLCENKTTHEIVAIKSIHKSRLIQSNKVHTVIAERNILTKVQHPFIVSLRFAFQTASKFYLGLEYAPG--GELFFHMQKNGS---
..|. .||.| .|||..| .| |..||||| |.           ... |..|| | .||.|| |  .||. ...|. .||..|  |.|| ...|.|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LPLYDIKLYIAEICMALHHLHSIGIVYRDLKPENILLDKDGYIKLTDFGLSKDMSYATQTNTFCGTSEYLAPEIVHRQPYTV-AVDWWAVGILTYEL
   .|  ... |...|| || ..|| ||..|||||||||||.   ||..||||.. .      .||||| .|.|||..   .|.  ..|||..|.. ||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LFGVTPFAHSNRARLFQNILEKEPTFPINTNPQILRFISALLTKDAKLRPNYDQIIQ-------MPFF
| | .||   . ...|..|.           |. . ||. .|.|| . ||   .. |       .|.|
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 93622.m00042.AA RSK-Unclassified 89-306 40 2e-94 297.03 In-house 1-242 (283) Show / Hide 
Range on Protein: 89-306
Range on HMM: 1-242/283
Sequence Identity: 40% (97 aa)

FKIIAVIGRGFYGKVMLCENKTTHEIVAIKSIHKSRLIQSNKVHTVIAERNILTKVQHPFIVSLRFAFQTASKFYLGLEYAPGGELFFHMQ--KNGSLPL
|  .  ||.|  ||| | . | |  | |.|  ||...|. ||.  |. |.||.   .||||| | ..|||  . || .|| .||..| |.|  |   .  
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

YDIKLYIAEICMALHHLHSIGIVYRDLKPENILLDKDGYIKLTDFGLSKDM----------------------SYATQTNTFCGTSEYLAPEIVHRQPYT
 |.. |..|. .|| .||  ...||||||.||.|...| ..||||.||..                       .  . || |||| ||||||.. |   |
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

VAVDWWAVGILTYELLFGVTPFAHSNRARLFQNILEKEPTFP
 |||||  ||. ||.|||..|.   |.  .|.||. ..  ||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFP
Kinase 93622.m00042.AA PKA 89-328 40 5.7e-94 318.49 In-house 1-246 (263) Show / Hide 
Range on Protein: 89-328
Range on HMM: 1-246/263
Sequence Identity: 40% (101 aa)

FKIIAVIGRGFYGKVMLCENKTTHEIVAIKSIHKSRLIQSNKVHTVIAERNILTKVQHPFIV-SLRFAFQTASKFYLGLEYAPGGELFFHMQKNGSLPLY
|.||...|.| .|.|||| .|.. ...|.| . |.. .. . |. |. |.|||. ..||||| .. . ||.... |. .||.||||.| ...|.|... .
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

DIKLYIA-EICMALHHLHSIGIVYRDLKPENILLDKDGYIKLTDFGLSKDMSYATQTNTFCGTSEYLAPEIVHRQ-PYTVAVDWWAVGILTYELLFGVTP
. |.|.| .|. ||  |||  |.||||||||||.||.|.||.|||| .| .     | | ||| |||||||. .  ..  .||||| ||| ||.|.|..|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FAHS--NRARLFQNILEKEPTFPINTNPQI---LRFISALLTKDAKLR
|  .  . . ... |.. .  || . ...      .|. ||..| . |
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKR
Kinase 93622.m00042.AA RSK 92-340 39 8e-93 314.69 In-house 1-278 (278) Show / Hide 
Range on Protein: 92-340
Range on HMM: 1-278/278
Sequence Identity: 39% (110 aa)

IAVIGRGFYGKVMLCENK---TTHEIVAIKSIHKSRLIQSNK-VHTVIAERNILTKVQ-HPFIVSLRFAFQTASKFYLGLEYAPGGELFFHMQKNGS---
. | |.| |||| ||  .    |  | | | ..|. ..|..| . .. .|||||  .| |||||.|  |||| .|.|| .|| .||||| | || ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LPLYDIKLYIAEICMALHHLHSIGIVYRDLKPENILLDK---DGYIKLTDFGLSKDM--SYATQTNTFCGTSEYLAPEIVH---RQP-YTVAVDWWAVGI
.   . . |.||| .|. |||. ||..|||||||||.|    .| |||||||..| .  ..  .|.|||.| ||.|||..    .|  .. |.|||  |.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LTYELLFGVTPFAH---SNRARLFQNILEKE--PTFP--INTNPQILRFISALLTKDAKLRPN-----YDQIIQMPFF
| ||.|.| .||..   .||. ....|....  .|.|   .  .    .|...|..| . |..      ..| | |.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 93622.m00042.AA PKC 89-340 39 2.7e-90 292.86 In-house 1-262 (262) Show / Hide 
Range on Protein: 89-340
Range on HMM: 1-262/262
Sequence Identity: 39% (103 aa)

FKIIAVIGRGFYGKVMLCENKTTHEIVAIKSIHKSRLIQSNKVHTVIAERNIL-TKVQHPFIVSLRFAFQTASKFYLGLEYAPGGELFFHMQKNGSLPLY
|. . |.|.| .||||| | | | |. ||| . |   ||   |  . .|. .| .  .||| ..|   ||| .. .  .||  || | ||.|. . ....
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

DIKLYIAEICMALHHLHSIGIVYRDLKPENILLDKDGYIKLTDFGLSKD-MSYATQTNTFCGTSEYLAPEIVHRQPYTVAVDWWAVGILTYELLFGVTPF
  . | |||..||. ||. ||.||||| .|.|||..| ||..|||..|. | . . |.||||| .|.||||.  |.|. .||||| |.| ||.. |  ||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

AHSNRARLFQNILEKEPTFPINTNPQILRFISALLTKDAKLR----PNY----DQIIQMPFF
   .   |||.|....| .|.     .   .....||. . |    |      . | . |||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 93622.m00042.AA Pkinase 89-340 32 4.6e-85 293.69 Pfam 1-293 (293) Show / Hide 
Range on Protein: 89-340
Range on HMM: 1-293/293
Sequence Identity: 32% (96 aa)

FKIIAVIGRGFYGKVMLCENKTTHEIVAIKSIHKSRLIQSNKVHTVIA--ERNILTKVQHPFIVSLRFAFQTASKFYLGLEYAPGG----ELFFHMQ--K
..|. .||.| .|.| .| .| | .|||.| | |.  . |.|  | .   |  |. ...||.|| |. .|.. .. |. .||..||    .|| ...  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

NGSL--PLYDIKLYIAEICMALHHLHSIGIVYRDLKPENILLDKDGYI----KLTDFGLSKD--MSYATQTNTFCGTSEYLAPEIVH-RQPYTVAVDWWA
.|..  .  ..| |. .|. .| ..|| ||..|||||||||.|..|.|    |..||||.|       . ..|||||..|.|||..  .|.|. .||.|.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

VGILTYELLFGVTPFAHS------NRARLFQNILEKEPTFPINTN---------------------PQILRFISALLTKDAKLRPNYDQIIQMPFF
.|.. ||.|.| .|| ..      .   ....|..... |.. .                      .  . ||. .|.|| | ||. .|| | |.|
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 93622.m00042.AA p70 89-340 37 1.8e-81 276.98 In-house 1-299 (299) Show / Hide 
Range on Protein: 89-340
Range on HMM: 1-299/299
Sequence Identity: 37% (111 aa)

FKIIAVIGRGFYGKVMLCENKT---THEIVAIKSIHKSRLIQSNK--VHTV------------------------IAERNILTKVQHPFIVSLRFAFQTA
|. . |.|.| ||||..    |   |  | | | . |   . . |   ||                          ||||||  |.||||. | .|||| 
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

SKFYLGLEYAPGGELFFHMQKNGSLPLYDIKLYIAEICMALHHLHSIGIVYRDLKPENILLDKDGYIKLTDFGLSK-DMSYATQ----------TNTFCG
.| || ||| .||||| |  . | ..    . | .|| .|| |||. ||.||||||||..|.. | ..||||||.|  .   .           | ||||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TSEYLAPEIVHRQPYTVAVDWWAVGILTYELLFGVTPFAHSNRARLFQNILEKE--PTFPINTNPQILRFISALLTKDAKLRPN-----YDQIIQMPFF
| || ||||. |  .  |||||. |.| |  | |. ||  .||.     ||     .. |    .     | .|| .....| .       .| . |||
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 93622.m00042.AA Ciliate-E2 89-340 24 1.7e-79 270.43 In-house 1-365 (365) Show / Hide 
Range on Protein: 89-340
Range on HMM: 1-365/365
Sequence Identity: 24% (91 aa)

FKIIAVIGRGFYGKVMLCEN-----------------------KTTHEIVAIKSIHKSRLIQSNKVHTVI----------AERNILTKVQHPFIVSLRFA
.|.| .||.| .|.| .|..                       |..  |.|.|...|. ..| ...  ..           |.||| ...||.|. .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--TASKFYLGLEYAPGGELFFHMQKN-----------GSLPLYDIKLYIAEIC---------------MALHHLHSIG-IVYRDLKPENILLDKDGYI
||  . ...|| .||. ||.|| ....|           ... .. || ....|.                ||..||| . |..||.||||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGLSK----------------DMSYAT-----------------QTNTFCGTSEYLAPEIVHRQP---------YTVAVDWWAVGILTYELLFGVT
|..||||||                 . .                   ..||.||| .|.||||. ...         |. ..|.|..|.. ||.||| .
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFAHSNRARLFQNILEKEPTFP------------------INTNPQILRFISA----LLTKDAKLRPN-YDQIIQMPFF
||        .|.|....  ||                   .  ..   .|.     .| || . |.. ..||.. |.|
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 93622.m00042.AA Pkinase_Tyr 89-245 23 1.7e-17 59.87 Pfam 1-174 (270) Show / Hide 
Range on Protein: 89-245
Range on HMM: 1-174/270
Sequence Identity: 23% (41 aa)

FKIIAVIGRGFYGKVMLCENK----TTHEIVAIKSIHKSRLIQSN-KVHTVIAERNILTKV-QHPFIVSLRFAFQ-TASK--FYLGLEYAPGGELFFHMQ
 ... ..|.| .|.|.... |     |.  ||.|.. |    ... .    ..| .|...  .|| ||.|  .          |. .||.|.| |  . .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K----NGSLPLYDIKLYIAEICMALHHLHSIGIVYRDLKPENILLDKDGYIKLTDFGLSKDM----SY-ATQTNT
|    ...|.. |.  . ..|.... .|.|.... |||   |.|..... .| .||||..|.     |  .....
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGG
Kinase 93622.m00042.AA TyrKc 89-338 19 1.1e-16 47.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 89-338
Range on HMM: 1-280/280
Sequence Identity: 19% (56 aa)

FKIIAVIGRGFYGKVMLCENKTTHEIVAIKSIHKSRLIQSNKVHTVIAERNILTKV--QHPFIVSLRFAFQTA-------SKFYLGLEYAPGGELFFHMQ
 . . ..|.|..|.|.... |   . ||.|.....       .   . | .|..|.  .|| || |  .  .           .. .||.|.| |  . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KNGS-LPLYDIKLYIAEICMALHHLHSIGIVYRDLKPENILLDKDGYIKLTDFGLSKDMSYA------TQTNTFCG--TSE------YLAPEIVHRQPYT
|..  |.. |   .   |.    .||| ... |||   |.|..... .| .|||||.|          ... .  .   .        .|||      .|
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

VAVDWWAVGILTYELL-FGVTPFAH-----SNRARLFQNILEK-EPTFPIN--------TNPQILRFISALLTKDAKLRPNYDQIIQMP
 . | |. |.. .|.. .| .|         . ....... .   .  | |          . . . ..     |.. ||.  .|..  
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 93622.m00042.AA S_TK_X 341-401 34 1.4e-10 42.39 SMART 1-79 (79) Show / Hide 
Range on Protein: 341-401
Range on HMM: 1-79/79
Sequence Identity: 34% (27 aa)

EGINFDDLLA--KKIKPTFIPRVE----KSTQPINFDKEFTQETPQDSFVLP-VFGSAEQ-----------FPGFSYVD
 ||..|.|..  |.|.| |.|..       |   |||.||| ||| .. . | ...|. |           |.||.|| 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 93622.m00042.AA Pkinase_C 369-403 42 0.00025 18.57 Pfam 10-46 (46) Show / Hide 
Range on Protein: 369-403
Range on HMM: 10-46/46
Sequence Identity: 42% (16 aa)

NFDKEFTQETPQDSF---VLPVFGSAEQFPGFSYVDVT
|||.|||.|.|.|..        |  |.| ||.||   
NFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD