Gene 84404.m00108 (T.vaginalis)

84404.m00108

Species: T.vaginalis
Alias: 84404.m00108, TvagK0379
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
84404.m00108.AA Protein None 426 None Fasta, JSON
84404.m00108.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 84404.m00108.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 84404.m00108.AA PH 9-103 20 4.8e-12 47.27 SMART 1-82 (82) Show / Hide 
Range on Protein: 9-103
Range on HMM: 1-82/82
Sequence Identity: 20% (19 aa)

SSFYGWVRRKGRSGLWYKRFATLDGDILNLFKDENRSTLDKSFKMDSNAEITVISPIRFAIKNLEDPTDILTINCTNSDEATRWITALKGAAMPT
    ||...|. .  | ||...|..| | ..||.   .. .|. ...  ....     | |.. .     ... | ...|...|..|.. |. . 
VIKEGWLYKKS-K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDC-TVRE-P--CFEIHH-DR---TYYFQCESEEEMQEWMQAIQKAIHNN
PH 84404.m00108.AA PH 9-101 20 1.8e-10 40.38 Pfam 1-92 (92) Show / Hide 
Range on Protein: 9-101
Range on HMM: 1-92/92
Sequence Identity: 20% (20 aa)

SSFYGWVRRKGRSGLWYKRFATLDGDILNLFKDENRSTLDKSFKMDSNAEITVIS----PIRFAIKNLEDPTDILTINCTNSDEATRWITALKGAAM
    ||...||... | ||...| .. | ..||.. ... .|. ...  ..| ..    |  | |.. .   . ... . ...|...|..|.. |. 
VIKEGWLHKKGKRKSWKKRWFVLFNNCLYYYKDDK-YRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DR--RTYYFQAESEEEMNDWMQAIQSACR
Kinase 84404.m00108.AA AGC 111-362 27 2.3e-139 362.77 In-house 1-395 (395) Show / Hide 
Range on Protein: 111-362
Range on HMM: 1-395/395
Sequence Identity: 27% (111 aa)

FKILSVIGRGYYGKVMLVNKI------GTNELYAIKSVHKRL--------LVESGNTNQ-------ILAERNFLMRAK----------HPFLVS-LYFTF
|..| |||.| .|||.|| |       .|...||.| . |.          ||  .| .       . .||| |....          |||.|. |...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTESK--FYLGLEYVP--------GGNLRFHTHNIS-----TYPIPDAKLYTAE-------IGSAISYLHS-IGIIYRD-LKTENVLLDSEGHVKLVDFG
|....   |. .||.|        || . ...|.       . . . |. |.||       | .|. ||||  |||.|| || ||.|||..||.||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAADAT---------------------------------------------------QVKTANSFCG--TPEYLAPEIIQHKDYSFNVDEWS--LGILMC
|.                                                       . .....|||  ||||.||||.    |.. .| ||  ||.||.
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELFFGEHPFYDSN----------QHVMYQKII------ESKPAIP----------DYCDEELRDVINQLLTKDPQQRPS----------FAQLKCHRFF
|. .|  |||. |          .. |.|||.      . |. .|          .. ..|..| |..||.||| .|.           . ..| | .|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 84404.m00108.AA Akt 111-362 39 4.2e-103 330.42 In-house 1-264 (264) Show / Hide 
Range on Protein: 111-362
Range on HMM: 1-264/264
Sequence Identity: 39% (104 aa)

FKILSVIGRGYYGKVMLVNKIGTNELY-AIKSVHKRLLVESGNTNQILAERNFLMRAKHPFLVSLYFTFQTESKFYLGLEYVPGGNLRFHTHNISTYPIP
| .| |.|.| .|||.|| |  |...| |.|.  |. ... .   ....||| | . .|||.|.|.. |||. | |. ..|..|| | .| .   . . .
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

DAKLYTAEIGSAISYLHSIGIIYRD-LKTENVLLDSEGHVKLVDFGLAA-D-ATQVKTANSFCGTPEYLAPEIIQHKDYSFNVDEWS-LGILMCELFFGE
 |. | ||| .|| .||| .||||| || ||.|.|..||..| ||||.  .  ..  ....||||||||||||.. ....  || |. ||..| |. .| 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

HPFYDSNQHVMYQKIIESKPAIP--DYCDEELRDVINQLLTKDPQQRP-----SFAQLKCHRFF
 |||. ..|.|..|| ...  .|  |. . | .| |..||.||| .|.        ..| | .|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 84404.m00108.AA SGK 111-362 37 7.79999999999e-102 315.29 In-house 1-283 (283) Show / Hide 
Range on Protein: 111-362
Range on HMM: 1-283/283
Sequence Identity: 37% (107 aa)

FKILSVIGRGYYGKVMLVNKIGT------------------NELYAIKSVHKRLLV-------ESGNTNQILAER-NFLMRAKHPFLVSLYFTFQTESKF
|..|.||| | .|||..| . ..                    .||.|   |   .            . |.||| . |   ||||.|.| . |||. | 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLGLEYVPGGNLRFHTHNISTYPIPDAKLYTAEIGSAISYLHSIGIIYRDLKTENVLLDSEGHVKLVDFGLAA-DATQVKTANSFCGTPEYLAPEIIQHK
|. ..|| || . .|       | . |. |.||| .|. ||||. ||||||| ||.|||..||..| ||||.  .  . .|  .|||||||||||.....
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

DYSFNVDEWSLGILMCELFFGEHPFYDSNQHVMYQKIIESKPAIPDYCDEELRDVINQLLTKDPQQR----PSFAQLKCHRFF
 ..  || |.||... |. .|  |||. |   ||..|| ..  || .   . .| |..||.|||..|      |.. | | ||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 84404.m00108.AA S_TKc 111-362 32 6.4e-94 319.24 SMART 1-231 (231) Show / Hide 
Range on Protein: 111-362
Range on HMM: 1-231/231
Sequence Identity: 32% (87 aa)

FKILSVIGRGYYGKVMLVNKIGTNELYAIKSVHKRLLVESGNTNQILAERNFLMRAKHPFLVSLYFTFQTESKFYLGLEYVPG--GNLRFHTHNIST---
..|| .||.| .|||... ...|....||| ..          ..|. |.. |.. .||..| || .||. ...|. .||..|  |.|. . ..  .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---YPIPDAKLYTAEIGSAISYLHSIGIIYRDLKTENVLLDSEGHVKLVDFGLAADATQVKTANSFCGTPEYLAPEIIQHKDYSF-NVDEWSLGILMCEL
   .|  .|. |...| .|. |.|| |||.|||| ||.|||.  |.|. |||||.        ..|||||.|.|||..    |..  .| ||.|... |.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

FFGEHPFYDSNQHVMYQKIIESKPAIPDYCDEELRDVINQLLTKDPQQRPSFAQLKC-------HRFF
. |. ||.  ....|..||           ..|..| |...|.|||..||.  ..         | .|
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84404.m00108.AA PKC 111-362 38 2.3e-88 286.52 In-house 1-262 (262) Show / Hide 
Range on Protein: 111-362
Range on HMM: 1-262/262
Sequence Identity: 38% (102 aa)

FKILSVIGRGYYGKVMLVNKIGTNELYAIKSVHKRLLVESGNTNQILAERNFLMRA-KHPFLVSLYFTFQTESKFYLGLEYVPGGNLRFHTHNISTYPIP
|. | |.|.| .|||||. . ||.|.|||| . | . ..       ..|.  |  | |||||..|. .|||... .  .||| || | ||  ..   . .
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

DAKLYTAEIGSAISYLHSIGIIYRDLKTENVLLDSEGHVKLVDFGLA-ADATQVKTANSFCGTPEYLAPEIIQHKDYSFNVDEWSLGILMCELFFGEHPF
 |. | ||| .|  .||. |||||||| .|||||.|||.|..|||..    .. .|...|||||.|.||||.| ..|...|| |..|.|| |.  |  ||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YDSNQHVMYQKIIESKPAIPDYCDEELRDVINQLLTKDPQQR----PS----FAQLKCHRFF
   .   . | | . .| .| .  .|  ... ...||.|..|    |.    .   . | ||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 84404.m00108.AA RSK 114-362 36 8.4e-84 284.72 In-house 1-278 (278) Show / Hide 
Range on Protein: 114-362
Range on HMM: 1-278/278
Sequence Identity: 36% (101 aa)

LSVIGRGYYGKVMLVNKI---GTNELYAIKSVHKRLLVESGN-TNQILAERNFLMRAK-HPFLVSLYFTFQTESKFYLGLEYVPGGNLRFHTHNIST---
|.| |.| |||| |. |.    |. .|| | ..|. .| .   |   ..||| |.| . |||.|.|. .||||.|.|| .||..|| |  |  .  .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

YPIPDAKLYTAEIGSAISYLHSIGIIYRDLKTENVLLDS---EGHVKLVDFGLAAD-ATQ-VKTANSFCGTPEYLAPEIIQ---HKD-YSFNVDEWSLGI
    .|. | ||| .|...||. |||.|||| ||.|.|.   |||.||.|||..     .  . ...||.| ||.|||..    ..  .. ..| ||||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LMCELFFGEHPFYD---SNQHVMYQKIIESK--PAIP--DYCDEELRDVINQLLTKDPQQRPS-----FAQLKCHRFF
|| |...|  ||.    .|...  ..| . |  . .|  .|  .| .| |...|..||..|..      ...| | .|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 84404.m00108.AA AktR 111-362 38 7.4e-83 281.57 In-house 1-268 (268) Show / Hide 
Range on Protein: 111-362
Range on HMM: 1-268/268
Sequence Identity: 38% (103 aa)

FKILSVIGRGYYGKVMLVNKI-GTNELYAIKSVHKRLLVESGNTNQILAERNFLM-RAKHPFLVSLYFTFQTESKFYLGLEYVPGGNLRFHTHNISTYPI
|... ..|.| .|||.|| |   ....||.|...|  ..|     ... ||| .   ..|||.| |...|||..| .. .||.||| | .|  .. .   
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

PDAKLYTAEIGSAISYLHSI-GIIYRDLKTENVLLDSEGHVKLVDFGLAA---DATQVKTANSFCGTPEYLAPEIIQH-KDYSFNVDEWSLGILMCELFF
 .|. | |.|  |. |||.   ||||||| || |||..||||..||||.    .     .|.||||||||.|||.|.  | . ..|| |..||.  |. .
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GEHPFYDSNQHVMYQKIIESK---PAIPDYCDEELRDVIN-QLLTKDPQQRPS-----FAQLKCHRFF
|  |||..||  |.|||...    . .| |  ....| |. .|| |.|..|.      . ..| | .|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 84404.m00108.AA Pkinase 111-362 29 2.8e-79 274.47 Pfam 1-293 (293) Show / Hide 
Range on Protein: 111-362
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

FKILSVIGRGYYGKVMLVNKIGTNELYAIKSVHKRLLVESGNTNQIL-AERNFLMRAKHPFLVSLYFTFQTESKFYLGLEYVPGG----NLR------FH
..|...||.| .|.| .  ..||....|.| . ||   .. . . .. .|   . | .||. | || .|..... |. .||..||     |        |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

THNISTYPIPDAKLYTAEIGSAISYLHSIGIIYRDLKTENVLLDSEGHV----KLVDFGLAAD--ATQVKTANSFCGTPEYLAPEIIQ-HKDYSFNVDEW
.  .   .  ..| |  .| ... |.|| |||.|||| ||.|.|..||.    |. |||||.         ...|||||.|.|||.|. ...|.  || |
GCFY--FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGILMCELFFGEHPFYDS------NQHVMYQKIIESKPAIPDYCD---------------------EELRDVINQLLTKDPQQRPSFAQLKCHRFF
|.|... |...|. ||...      .| .|...| . ..  . . .                     ||..|.|. .|.|||..||...|...| .|
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 84404.m00108.AA p70 111-362 35 2.4e-78 266.59 In-house 1-299 (299) Show / Hide 
Range on Protein: 111-362
Range on HMM: 1-299/299
Sequence Identity: 35% (107 aa)

FKILSVIGRGYYGKVMLVNKIG---TNELYAIKSVHKRLLVESG-NTNQIL-------------------------AERNFLMRAKHPFLVSLYFTFQTE
|. | |.|.| ||||..| |     |. .|| |   |.  | .   |                             |||| |   ||||.. | . |||.
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

SKFYLGLEYVPGGNLRFHTHNISTYPIPDAKLYTAEIGSAISYLHSIGIIYRDLKTENVLLDSEGHVKLVDFGLAADATQVKTA-----------NSFCG
.| || ||| .|| |  |    ....   |. | .||  |. .||. |||||||| ||..|.. |||.| ||||     .  .             .|||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TPEYLAPEIIQHKDYSFNVDEWSLGILMCELFFGEHPFYDSNQHVMYQKIIESK--PAIPDYCDEELRDVINQLLTKDPQQRPS-----FAQLKCHRFF
|.|| ||||.  . .. .|| ||||.||   . |  ||  .|  .   ||.  |  ...| |  .| || |..|| ..|.||        |. . | ||
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 84404.m00108.AA Delta 111-362 37 6.2e-76 258.58 In-house 1-259 (259) Show / Hide 
Range on Protein: 111-362
Range on HMM: 1-259/259
Sequence Identity: 37% (98 aa)

FKILSVIGRGYYGKVMLVNKIGTNELYAIKSVHKRLLVESGNTNQILAERNFLMRA-KHPFLVSLYFTFQTESKFYLGLEYVPGGNLRFHTHNISTYPIP
|... |.|.| .|||||.   |.|. ||||.. |  ..|   ..  . ||  |. | .||||  |. ||||... .  .||. || | .|  ..  .   
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK

DAKLYTAEIGSAISYLHSIGIIYRDLKTENVLLDSEGHVKLVDFGLA-ADATQVKTANSFCGTPEYLAPEIIQHKDYSFNVDEWSLGILMCELFFGEHPF
 |. |..|| ... .||. |||||||| .||||| .||.|. |||..  . .. |.|..|||||.|.|||||. . |...|| || |.|| |.  |  ||
RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPF

YDSNQHVMYQKIIESKPAIPDYCDEELRDVINQLLTKDPQQRPSF-----AQLKCHRFF
   .   ... |.. .|  | . ..| .|....|. .||..|         ... | ||
HGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF
Kinase 84404.m00108.AA PKA 111-362 39 3.6e-75 256.05 In-house 1-263 (263) Show / Hide 
Range on Protein: 111-362
Range on HMM: 1-263/263
Sequence Identity: 39% (104 aa)

FKILSVIGRGYYGKVMLVNKIGTNELYAIKSVHKRLLVESGNTNQILAERNFLMRAKHPFLV-SLYFTFQTESKFYLGLEYVPGGNLRFHTHNISTYPIP
|.|. ..|.| .|.|||. . .. . ||.|   |.  |    .  .. |.| |.  ||||.| ..|.|||.... |. .|||||| .  .  .    . |
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

DAKLYTA-EIGSAISYLHSIGIIYRDLKTENVLLDSEGHVKLVDFGLAADATQVKTANSFCGTPEYLAPEIIQHK-DYSFNVDEWSLGILMCELFFGEHP
.||.| | .| .|. ||||  ||||||| || |.|..||.|. |||  |  ..  |  . ||||||||||||| |  .   || |.||||  |. .|  |
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFG-FAKKVDDRTW-TLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FYDS--NQHVMYQKIIESKPAIPDYCDEEL---RDVINQLLTKDPQQRP---SF--AQLKCHRFF
|||.  ..  .|.||.. |   | . |  .   .| |..||..|. .|    ..   . | |..|
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 84404.m00108.AA Ciliate-E2 111-362 22 2.5e-74 253.22 In-house 1-365 (365) Show / Hide 
Range on Protein: 111-362
Range on HMM: 1-365/365
Sequence Identity: 22% (84 aa)

FKILSVIGRGYYGKVMLVNKIGTNE-----------------------LYAIKSVHKRLLVESGNTNQIL----------AERNFLMRAKHPFLVSLYFT
.|.. .||.| .|.| ..... ...                       .||.|...|. . .  . ..|.           |.| | . .||... .| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--TESKFYLGLEYVPGGNLRFHTHNISTYP-----------IPDAKLYTAEIGS---------------AISYLHSIG-IIYRDLKTENVLLDSEGHV
||  .....|| .||. ||.|. .  | ..             .  .| ....| .               |. |||| . ||.||.| ||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLVDFGLAADATQV--------------------------------KTANSFCGTPEYLAPEIIQ---------HKDYSFNVDEWSLGILMCELFFGEHP
|..||||. ....                                  ..|..||||.|.||||..         .|.|.. .| ||||... |. ||..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FYDSNQHVMYQKIIESKPAIP------------------DYCDEELRDVINQ----LLTKDPQQRPS-FAQLKCHRFF
|        .|.|.. |  .|                  .....|  | |..    .| |||..|.. . |.. | .|
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 84404.m00108.AA TyrKc 111-361 22 6.8e-18 66.56 SMART 1-280 (280) Show / Hide 
Range on Protein: 111-361
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

FKILSVIGRGYYGKVML-VNKIGTNELYAIKSVHKRLLVESGNTNQILAERNFLMRA--KHPFLVSLYFTFQTE-------SKFYLGLEYVPGGNL----
 . . ..|.| .|.|.. . |    .  |.|....           .. | . ...   .|| .| ||    ..          .. .||.|.|.|    
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

RFHTHNISTYPIPDAKLYTAEIGSAISYLHSIGIIYRDLKTENVLLDSEGHVKLVDFGLAADAT---------QVKTANSFCGTPE-----YLAPEIIQH
| | ..    . .|   .   | .  .|||| ..| ||| . |.|......||  ||||. | .         ..... .  |.        .||| |..
RKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

KDYSFNVDEWSLGILMCELF-FGEHPFYD------SNQHVMYQKIIESKPAIPDY--------CDEELRDVINQLLTKDPQQRPSFAQLKCHRF
. ...  | || |..| |.| .|. | ..      |||.|. .      . .|..        | .|. ... |    || .||.|... ...|
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase 84404.m00108.AA Pkinase_Tyr 111-362 24 7.4e-17 57.71 Pfam 1-270 (270) Show / Hide 
Range on Protein: 111-362
Range on HMM: 1-270/270
Sequence Identity: 24% (68 aa)

FKILSVIGRGYYGKVMLVNKI----GTNELYAIKSVHKRLLVESGN--TNQILAERNFLMRA-KHPFLVSLYFTFQ-TESK--FYLGLEYVPGGNLRFHT
 ... ..|.| .|.|..        .|.   |.|.. |     . .      ..| . ..   .|| .|.||      .     |. .||.|.|.|. . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

HN----ISTYPIPDAKLYTAEIGSAISYLHSIGIIYRDLKTENVLLDSEGHVKLVDFGLAADA----TQ-VKTANSFCGTPEYLAPEIIQHKDYSFNVDE
..        ...|   . ..| .. .||.|...| ||| . |.|......||  ||||| |     .  .|. ..       .||| |... ..   | 
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDV

WSLGILMCELFF-GEHP-FYDSNQHVMYQKI-IESK-PAIPDYCDEELRDVINQLLTKDPQQRPSFAQLKCHRFF
|| |.|| |.|  || | ...   . .|..|  .    ..|..| .|. |.. |   .||..||.|...  |...
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL
Kinase 84404.m00108.AA S_TK_X 363-423 26 3.2e-14 54.47 SMART 1-79 (79) Show / Hide 
Range on Protein: 363-423
Range on HMM: 1-79/79
Sequence Identity: 26% (21 aa)

LDIDWEKLLK--REIKPVYVPTTQ----DPLDLSHFDSCFTNESAADSFVQPAFGDISN------------VQGFSYYK
 .|||.||..  .||.| ..|. .    .| |.| || .||.|.. .. ..|.  ....              ||.|  
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 84404.m00108.AA Pkinase_C 382-425 29 0.000941 16.55 Pfam 1-46 (46) Show / Hide 
Range on Protein: 382-425
Range on HMM: 1-46/46
Sequence Identity: 29% (14 aa)

TTQDPLDLSHFDSCFTNESAADSF---VQPAFGDISNVQGFSYYKNE
.  .|.| |.|| .||.|.. |..        || .. .||.|   .
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD