Gene 90316.m00115 (T.vaginalis)

90316.m00115

Species: T.vaginalis
Alias: TvagK0761, 90316.m00115
External Links:
Annotation:

Classification

Group: CMGC
Family: GSK

Sequence

Name Sequence Type Origin Length Description Download
90316.m00115.AA Protein None 335 None Fasta, JSON
90316.m00115.kin_dom Protein Kinase Domain None 283 None Fasta, JSON

Protein domain

Protein domains of 90316.m00115.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90316.m00115.AA GSK 30-312 35 1.1e-96 295.88 In-house 1-328 (328) Show / Hide 
Range on Protein: 30-312
Range on HMM: 1-328/328
Sequence Identity: 35% (117 aa)

FKSINVIGSGAFGVVYCA-MG----HNGET----CAIKCAVDDPNYR-NREVKVFTRL---NHHNCIKMRSHFKSK-DKKYD--RTIENIVMEYLPDSLQ
.. ..|||.|.|||||.| |     ...|.     |||  . |..|. |||..  ..|   .| |..... .| .. .|| .  . ....||||.|  |.
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLVMEYMPQTLY

NYDRQLAQNNEHLPIWMVKLFAYQMFCGLRHMHTIGYIHRDIKPANLLIDVDAGILKLCDFGSSKRPKP--GQTCKSYVGSRPYRAIECILGSETYGAPI
.. |. . |.  .||  .||..||||.||.. | .|  |||||| |.|.| | |.||.|||||.|. .|  ...  ||  || ||| | |.|.. |.  |
QVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVLKICDFGSAKQLEPNKNEPNISYICSRYYRAPELIFGCTNYTCQI

DIWSAGCVITQMLTGVNPIFAASSTEELTNSIIHFLGTPSKEDIQDMEVKW---NPP-----KIHKKLLIE-------------------SHLPKHTPND
|.||.|||.  ||.|  |.|.  |.      ||  ||||.||.|| | ..    . |     .| .. .                         .||...
DVWSCGCVMAEMLKG-QPLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKPHPWQKNDTKYEYQTYYHKKYRTVYMFKWCHTDMQ

-IIDLLNHIFVYSPKKRLTAEQCMKHKCF
 .|||.. ..|| |||||.. ....|  |
DWIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase 90316.m00115.AA CMGC 30-312 19 8.1e-85 278.52 In-house 1-513 (513) Show / Hide 
Range on Protein: 30-312
Range on HMM: 1-513/513
Sequence Identity: 19% (100 aa)

FKSINVIGSGAFGVVYCA---------------MGHNGETCAIKCAVDDPNYRN----------------REVKVFTRLN----------------HHN-
.. |..||.|..|||| .               .  ..| .|||    .. | .                ||.|   .||                ||| 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

CIKMRSHFKSKD-KKYDRT----------IENIVMEYLPDSLQNYDRQLA------------------------QNNEHLPIWMVKLFAYQMFCGLR--H
..|.. .|..|. ....              ..|.||.. .| .| ..                          .|  ...|  .. ..||...||   .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

MHTIG--YIHRDIKPANLLIDVDA-------------------GILKLCDFGSSK--RPKPGQ--------------------TCKSYVGSRPYRAIECI
.|  .   ||||.||.|.||. .                    |.||.||||...   | ...                    .  .|| .| ||| | .
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

LGSETY---------GAPIDIWSAGCVITQMLTG-------VNPIFA-----------ASSTEELTNSIIHFLGTPS---------------KEDIQDME
||.. |         . |||.||.||..  |.||         |.|             .|. .  . |.  ||||.               .|.. .| 
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

VK------------------WN------------PPKIHKKLLIESHLPKH---------------------------------TPNDIIDLLNHIFVYS
 .                  |.             |....| . . . ...                                  . . ||||. ...| 
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

PKKRLTAEQCMKHKCF
|.||.||||...|  |
PDKRITAEQALQHPYF
Kinase 90316.m00115.AA S_TKc 30-312 23 1.3e-66 228.56 SMART 1-231 (231) Show / Hide 
Range on Protein: 30-312
Range on HMM: 1-231/231
Sequence Identity: 23% (69 aa)

FKSINVIGSGAFGVVYCAMGHN-GETCAIKCAVDDPNYRNREVKVFTRLNHHNCIKMRSHFKSKDKKYDRTIENIVMEYLPD---SLQNYDRQLAQNNEH
.. ...||.||||.||..  .. |. .|||.     .   ||...  . .| | .|.  .| .       .   .||||..    .|  | ..   .  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LPIWMVKLFAYQMFCGLRHMHTIGYIHRDIKPANLLIDVDAGILKLCDFGSSKRPKPGQTCKSYVGSRPYRAIECILGSETYGA-PIDIWSAGCVITQ
  .|  ... ..||..|.| ..|  | ||||.||.|.|.|     .|.||||....       ....|.. |.| | .     ||  ..|.|| ||..  
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MLTGVNPIFAASSTEELTNSIIHFLGTPSKEDIQDMEVKWNPPKIHKKLLIESHLPKHTPNDIIDLLNHIFVYSPKKRLTAEQCMK-------HKCF
||.|  |           . ... .|                                 . . .|........ |.||.|| ....       |  |
MLCGYPPFP-------QMQMMFKKIG---------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 90316.m00115.AA Pkinase 30-312 25 9.3e-52 183.06 Pfam 1-293 (293) Show / Hide 
Range on Protein: 30-312
Range on HMM: 1-293/293
Sequence Identity: 25% (81 aa)

FKSINVIGSGAFGVVYCAMGHNGET-CAIKCAVDDPNYRNR--------EVKVFTRLNHHNCIKMRSHFKSKDKKYDRTIENIVMEYLPD-----SLQNY
.. . .||||.||.|| .. .. .   |.|.   . .  .         |...  |||| | ....  | .||. |      .||||..      .|  |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY------MVMEYCEGGLYVMDLFDY

DRQLAQNNEHL--PIWMVKLFAYQMFCGLRHMHTIGYIHRDIKPANLLIDVDAGIL----KLCDFGSSKR--PKPGQTCKSYVGSRPYRAIECILGSETY
 .   ...  .  . | .| ..||...|| ..|  | ||||.||.|.||| . | .    |.||||..|     ... .....|...|.| | |.|.. |
IST--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYY

GAPIDIWSAGCVITQMLTGVNPIFAASSTEELTNSIIHFLGTPSKEDIQDMEVKW--------NPPKIHKKLLIESHLPKHTPNDIIDLLNHIFVYSPKK
| ..|.||.||.. .||.|  |   .  ...  .. .. .    . ..   . .|        .. . |     .. . . .. . .|... .. . |||
GPKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-H---F-HWTF-HNWSEECKDFIKWCLCKDPKK

RLTAEQCMKHKCF
|.||||...|. |
RPTAEQILQHPWF
Kinase 90316.m00115.AA CAMK 35-312 16 1.4e-47 151.0 In-house 1-425 (425) Show / Hide 
Range on Protein: 35-312
Range on HMM: 1-425/425
Sequence Identity: 16% (71 aa)

VIGSGAFGVVYCAMGH-NG------------ETCAIKC-----AVDD------------------------PNYRN---REVKVFTR-------LNHHNC
..|.|.||.|. ..   ..            . .|||      . |.                        |. |    ||...  .       |.| | 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKMRSHFK------------SKDK--KYD-RTIENIVM---EYLPDS--LQN-YDRQLAQNN-------------EHLPIWMVKLFAYQMFCGLRHMHTI
||.  ..             . .|    . ..   .||   || .    ..  .|.  .. .              ... . .. .  |. ......|  
IKLYEVYEDPHYFKNTNDYET-SKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

GYIHRDIKPANLLIDVDA----------------GILKLCDFGSSKRPKP------------------------GQTCKSYVGSRPYRA-IECILG----
. .|||.|| |.|.| .                 . .|..||| ... .|                        || .| ..|. .| |  | ..|    
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------SETYGAPIDIWSAGCVITQMLTGVNPIFAASSTEELTNSIIHFLGTPSKEDIQDMEVKWNPPKIHKKLLIESH--LPKHTPN---------
          . || ..|.||.|..   ||.|  |  . .  |..  .                 .. |......| .       |.. ..         
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-D--E-W------------IGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEW

--------------DIIDLLNHIFVYSPKKRLTAEQCMKHKCF
              . .||.... .. |.||.|.|||..|. .
WDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 90316.m00115.AA CDK 30-312 25 2.3e-46 146.23 In-house 1-284 (284) Show / Hide 
Range on Protein: 30-312
Range on HMM: 1-284/284
Sequence Identity: 25% (83 aa)

FKSINVIGSGAFGVVYCAMGHN-G-----ETCAIKCAVDDPN-------YRN----REVKVFTRLNHHNCIKMRSHFKSKDKKYDRTIE------NIVME
.. .. || |..|||| |  .. |     . .|.|.   . .         .    ||..    | |.| .| .  . .|.. ... .        .|.|
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFE

YLPDSLQNYDRQLAQNNEHLPIWMVKLFAYQMFCGLRHMHTIGYIHRDIKPANLLIDVDAGI-----LKLCDFGSSKRPK-------PGQTCKSYVGSRP
|..  |  | .             .| . .|.  || ..|  . .|||.||.|.||. . |.     ||. ||| ..          | .|  . |  . 
YMDHDLKKYMD-------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILIN-NNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLW

YRAIECILGSETYG--APIDIWSAGCVITQMLT--GVNPIFAASSTEELTNSIIHFLGTPSKEDIQDMEVKWNPPKIHKKLLIESHLPKHTPNDIIDLLN
||| |  |||..|.   |||.||.||..  |.|     |.|  .|  .    |. ..|||. ..  ...   .                       ||||
YRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY----------------------DLLN

HIFVYSPKKRLTAEQCMKHKCF
. ..| ||||..|||...|. |
KMLCYDPKKRISAEQALQHPYF
Kinase 90316.m00115.AA Ciliate-E2 30-312 19 1.5e-42 143.88 In-house 1-365 (365) Show / Hide 
Range on Protein: 30-312
Range on HMM: 1-365/365
Sequence Identity: 19% (78 aa)

FKSINVIGSGAFGVVYCA-------M-----------------GHNGETCAIKCAV-DDPNYRNREVKVFT----------------RLNHHNCIKMRSH
.| |..||.|.||.|| .       .                 . ..   |.|.   .. .. ..| ...                 .||| | |||  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FK--SKDKKYDRTIENIVMEYLPD-SLQNYDRQL-AQNNEHLP------IWMVKLFAYQMFC---------------GLRHMHTIG-YIHRDIKPANLLI
|.  .... |      .||||.   .|. | ..   . |....      .  .| . .| .                .|...|  .  ||||||| |.|.
FQEKDDNNIY------LVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF

DVDAGILKLCDFGSSKRPKPG--------------------------------QTCKSYVGSRPYRAIECILGSET--------YGAPIDIWSAGCVITQ
      .|..||| ||. ..                                 .. ....|. .| | | . | .         |.  .||||.|... .
------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE

MLTGVNPIFAASSTEELTNSIIHFLGTPSKEDIQDMEVKWNPP-----KIHKKLLIESHL----PKHTPNDIIDLLNH----IFVYSPKKRLT-AEQCMK
||.|  |                         .| .. |.. |     |  .. .|   .    .|. ... .||..     .... |.||.| .||...
MLFGKPPF-----------------------QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN

HKCF
|. |
HPWF
Kinase 90316.m00115.AA MAPK 131-312 30 1.5e-38 130.83 In-house 117-328 (328) Show / Hide 
Range on Protein: 131-312
Range on HMM: 117-328/328
Sequence Identity: 30% (65 aa)

VKLFAYQMFCG--LRHMHTIGYIHRDIKPANLLIDVDAGILKLCDFGSSKRPKPGQTCK---------------SYVGSRPYRAIECILG--SETYGAPI
.. | ||. .|  | ..|  . ||||.||.|.|.. . . ||.|||| .    | ....                ||  | ||| | .|.  .  |   .
IQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNEN-CDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAV

DIWSAGCVITQMLTGVNPIFAASSTEELTNSIIHFLGTPSKEDIQDME--------VKWNP-PKIHKKLLIESHLPK---HTPNDIIDLLNHIFVYSPKK
|.||.||    |||.  |.|  ... .  | |. .|||||.|.|| ..        .. .. .. ..|   |. .|.   ..  . ||||    | .|.|
DMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDK

RLTAEQCMKHKCF
|.|.|... |  |
RITVEEALQHPYF
Kinase 90316.m00115.AA ERK7 136-312 33 8.1e-38 126.71 In-house 107-292 (292) Show / Hide 
Range on Protein: 136-312
Range on HMM: 107-292/292
Sequence Identity: 33% (64 aa)

YQMFCGLRHMHTIGYIHRDIKPANLLIDVDAGILKLCDFG-----SSKR--PKPGQTCKSYVGSRPYRAIECILGSETYGAPIDIWSAGCVITQMLTGVN
||..  ...||    ||||.||.|.|.| .   .|.||||     ....   .  .    ||  | ||| |  |||..|   .| || ||.. .||.|  
YQLLRAIKYMHSGNVIHRDLKPSNILLDSEC-MVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGEMLRG-K

PIFAASSTEELTNSIIHFLGTPSKEDIQDMEVKW-----NPPKIHKKLLIESHLPKHTPNDIIDLLNHIFVYSPKKRLTAEQCMKHKCF
|.|. .|| .  . |.. .. |..|||.... .      .  . .|.  ..  .| ....| |||| .. |. |||||||||...|   
PMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMP-QCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase 90316.m00115.AA CAMKL 30-229 26 4.7e-32 99.46 In-house 1-235 (297) Show / Hide 
Range on Protein: 30-229
Range on HMM: 1-235/297
Sequence Identity: 26% (64 aa)

FKSINVIGSGAFGVVYCAMG-HN-GETCAIKCAV-----DDPNYRNR--------------EVKVFTRLN---HHNCIKMRSHFKSKDK-KYDRTIENIV
.. . ..| |.||.|  |.   . ||  |||        .||. ...              |..   .||   | | ||.  ..  ... .   .  ..|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV

MEYLPDS---LQNYDRQLAQNN---EHLPIWMVKLFAYQMFCGLRHMHTIGYIHRDIKPANLLIDVDAG-ILKLCDFGSSKRPKP-----GQTCKSYVGS
||| .     |..|   . ..    . .| .  . .  |. ... ..|  | .|||||| |.|.| .    .|..||| |   .|     ||..|   ||
MEYCSGGEMDLFDY---IVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGS

RPYRAIECILG--SETYGAPIDIWSAGCVITQMLTGVNP
 || | | ..|   . .| ..||||.| .   |..|  |
PPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLP
Kinase 90316.m00115.AA CDK-Unclassified 68-254 29 7.7e-32 101.92 In-house 56-262 (324) Show / Hide 
Range on Protein: 68-254
Range on HMM: 56-262/324
Sequence Identity: 29% (63 aa)

NREVKVFTRLNHHNCIKMRSHFKSKDKKY--------DRTIENIVMEYLPDSLQNYDRQLAQNNEHLPIWMVKLFAYQMFCGLRHMHTIGYIHRDIKPAN
.||...  ..||.| ||.   . . |.           . .  .|||| |. . |   ||  |   |    .. |. ||. |.  .|  . .||||||.|
QREISCLQNCNHMNIIKFMDMHYDHDRCSKNPYYDNLHPSFY-MVMEYMPYTWYN---QLHNNRYNLSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQN

LLIDVDAG-----ILKLCDFGSSKRPK-------------PGQTCKSYVGSRPYRAIECILGSETYGAPIDIWSAGCVITQMLTGVNPIFAASSTEELTN
..|. . .     .||. |||..                 |.|   . |  | ||| |  .||  |.  .||||.||.. ... |. |||.  .  |   
IMIT-NNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQQYSTQVSTRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWFQGK-PIFQGRTEIEQMH

SIIHFLGTPSKED
 |.  ||||. ..
HIFKMLGTPCEDM
Kinase 90316.m00115.AA STE 141-312 22 5.2e-27 92.49 In-house 163-359 (359) Show / Hide 
Range on Protein: 141-312
Range on HMM: 163-359/359
Sequence Identity: 22% (50 aa)

G-LRHMHTIGYIHRDIKPANLLIDVDAGILKLCDFGSSKRPKP-----------------GQTCKSYVGSRPYRAIECILG-----SETYGAPIDIWSAG
| | . |  ..||||||||| |.       |||||| ...  .                 .| ... ||.  . | | |..     .  |..  |||| |
GLLYYLHSHHIIHRDIKPANILL------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLG

CVITQMLTGVNPIFAASSTEELTNSIIHF-------------LGTPSKED-------------IQDMEVKWNPPKIHKKLLIESHLPKHTPNDIIDLLNH
|.|  |.||  | .  . .. . . .. .              . |. .|              .                    .|..   . .| .|.
CTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGT-T------------------YPHKWSPEFKDFINK

IFVYSPKKRLTAEQCMK--HKCF
 ... |.|| ||.| .|  |. .
CLQKDPNKRPTASQLLKSEHPFI
Kinase 90316.m00115.AA TyrKc 30-312 20 5.8e-12 -29.25 SMART 1-280 (280) Show / Hide 
Range on Protein: 30-312
Range on HMM: 1-280/280
Sequence Identity: 20% (64 aa)

FKSINVIGSGAFGVVYCAMGHNGETCAIKCAVDDPNYRN--REVKVFTRL--NHHNCIKMRSHFKSK-------DKKYDRTIENIVMEYLPD-SLQNYDR
 . . ..|.||||.|| ..    ...|.|.  .|   .   || .. ..|  .| | ...     ..       .  .      ||||| |  .|..| |
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM------IVMEYMPHGDLKDYLR

QLAQNNEHLPIWMVKLFAYQMFCGLRHMHTIGYIHRDIKPANLLIDVDAGILKLCDFGSSKRPKPG--------QTCKSY--VGS--RPYR--AIECILG
    .   |.      |..|  || .. |  ..||||.   | |.. .  . | .||| |.  . .           |.    |    |.|  |.|||  
KHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-N

SETYGAPIDIWSAGCVITQMLTGVNPIFAA-----SSTEELTNSIIHFLGTPSKED---IQDMEVKWNPPKIHKKLLIESHLPKHTPNDIIDLLNHIFVY
  ..    |.|| | ..  ..|   .          | .|. . . .    |  ..   .                   .    . | .. ..      .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------F---VCCPDEMYQIMKQCWHE

SPKKRLTAEQCMKHKCF
 |..| | ...  |.||
DPEDRPTFSEI--HECF
Kinase 90316.m00115.AA CAMKL 278-312 31 7.8e-10 27.41 In-house 264-297 (297) Show / Hide 
Range on Protein: 278-312
Range on HMM: 264-297/297
Sequence Identity: 31% (11 aa)

PKHTPNDIIDLLNHIFVYSPKKRLTAEQCMKHKCF
..| . | .||. .. .  |.|| |..| |.|. .
WYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 90316.m00115.AA STE 30-109 23 1.9e-09 29.64 In-house 1-120 (359) Show / Hide 
Range on Protein: 30-109
Range on HMM: 1-120/359
Sequence Identity: 23% (28 aa)

FKSINVIGSGAFGVVYCAMGHN----------------GETCAIK-CAVDDPN-----------------YRN---REVKVFTRLN--HHNCIKMRSHFK
.. | .||.||||.||.|| |.                || .|||   ... |                  ..   .|.|.  ..|  | | .|   .. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SKDK-KYDRTIENIVMEYLP
 ... . ...  .|.|||..
KEGHNHKNDDELWICMEYMD
Kinase 90316.m00115.AA Pkinase_Tyr 30-81 23 0.000156 15.98 Pfam 1-65 (270) Show / Hide 
Range on Protein: 30-81
Range on HMM: 1-65/270
Sequence Identity: 23% (15 aa)

FKSINVIGSGAFGVVYCAMGH-----NGETCAIKCAVDDPNYRN-------REVKVFTRL-NHHN
 . . ..|.||||.|| .  .     .. ..|.|.  ..   ..       ||.|. . | .|.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPN
Kinase 90316.m00115.AA CDK-Unclassified 286-312 18 0.000256 9.96 In-house 298-324 (324) Show / Hide 
Range on Protein: 286-312
Range on HMM: 298-324/324
Sequence Identity: 18% (5 aa)

IDLLNHIFVYSPKKRLTAEQCMKHKCF
....    .|.|..|.....  .|  |
NNCEFQMVMYQPYNRWKCMEILQHPWF
Kinase 90316.m00115.AA MAPK 30-58 33 0.000756 8.93 In-house 1-36 (328) Show / Hide 
Range on Protein: 30-58
Range on HMM: 1-36/328
Sequence Identity: 33% (12 aa)

FKSINVIGSGAFGVVYCAMGH-------NGETCAIK
.. .  ||.||.|||  |.         .|.. |||
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIK
Kinase 90316.m00115.AA CDK-Unclassified 30-47 33 0.00181 7.12 In-house 1-18 (324) Show / Hide 
Range on Protein: 30-47
Range on HMM: 1-18/324
Sequence Identity: 33% (6 aa)

FKSINVIGSGAFGVVYCA
 . . ..|.|.|| |. |
YRMQCKYGEGTFGCVCKA
Kinase 90316.m00115.AA Pkinase_Tyr 103-175 29 0.020244 8.82 Pfam 84-156 (270) Show / Hide 
Range on Protein: 103-175
Range on HMM: 84-156/270
Sequence Identity: 29% (23 aa)

IVMEYLPD-SLQNYDRQLAQN---NEHLPIWMVKLFAYQMFCGLRHMHTIGYIHRDIKPANLLIDVDAGILKLCDFG
||||| |  .| .|   | ..   ...|.. .   ...|  .|. . . ...||||.   | |.. .  . | ||||
IVMEYMPHGDLLDY---LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDFG
Kinase 90316.m00115.AA ERK7 30-58 26 0.126548 0.96 In-house 1-30 (292) Show / Hide 
Range on Protein: 30-58
Range on HMM: 1-30/292
Sequence Identity: 26% (8 aa)

FKSINVIGSGAFGVVYCAMGHN-GETCAIK
.. .  .| ||.|.|  |.    ... |.|
YEIRKRLGKGAYGIVWKAYDKRTKQVVALK