Gene 83956.m00144 (T.vaginalis)

83956.m00144

Species: T.vaginalis
Alias: 83956.m00144, TvagK0730
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: MST

Sequence

Name Sequence Type Origin Length Description Download
83956.m00144.AA Protein None 445 None Fasta, JSON
83956.m00144.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of 83956.m00144.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PBD 83956.m00144.AA PBD 2-18 55 2e-06 25.4 Pfam 1-18 (60) Show / Hide 
Range on Protein: 2-18
Range on HMM: 1-18/60
Sequence Identity: 55% (10 aa)

EISNP-TNFQHVTHIGQD
.||.| |||.|..|.| |
MISTPLTNFKHTMHVGWD
Kinase 83956.m00144.AA STE20 33-290 37 6.3e-99 334.96 In-house 1-288 (288) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-288/288
Sequence Identity: 37% (108 aa)

FKVIRKIGAGGFGDVYEMEHIPSGIH----MAGKSVSVEKMTR--TSKTHLAREIDLLRKVMSPYTVQYYGSIDFEGSP----MILLEFCNRGSLYDIMK
.. ..||| |..|.||   |.|.|       | | ...||      ..  .  ||. ... ..|. |.||||   . ..     |. |.|. ||| ||||
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---AKKM-----TFSEDQISVIMKDMITALIILHKNFHVLHRDVKAGNILLNSSCQIKLTDFGISCQFSS----TSSQRTQTITGTPYWMAPEIMND---
    ..      ...|.||..|....  .|  ||.| |. |||.||.||||... ..||.||| . |...    | ... .|. |||||||||...    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSN-HIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEG

--DHYGYPADIWSLGITAVELAEGQPPYSELPYTRALVEIS--TKGFPGFRK--GNKYTQEFVNFIRECTVMDPEKRPGPEQLLKHPFI
    |.| .||||||||| |.|||.|||.... .||. .|   ....| ...   .|...|| .|.  | ..|||||| ..||||||||
PDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase 83956.m00144.AA STE 33-290 27 4.1e-93 315.66 In-house 1-359 (359) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-359/359
Sequence Identity: 27% (102 aa)

FKVIRKIGAGGFGDVYEMEHI------PSGIH---------MAGKSVSVEKMT---------------RTSKTHLAREIDLLRKVM--SPYTVQYYGSID
.. |.||| |.|| ||   ..      ..|           || | ...|. .                . .  . .||....|    .|. |.|||.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

FEG-------SPMILLEFCNRGSLYDIMKAKKMT-------------FSEDQISVIMKDMITALIILHKNFHVLHRDVKAGNILLNSSCQIKLTDFGISC
 ||       .  | .|... ||| ||.| |...             |.|.||..| .. . .|  .. . |. |||.|..||||     .||.|||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QFSS---------------TSSQRTQTITGTPYWMAPEIMN------DDHYGYPADIWSLGITAVELAEGQPPYSELPYTRALVEISTK-----------
|...               |..|...|..||| |||||...      |..|.. .||||||.|..|.|.|.||.......||. .| ..           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----GFPGFRKG-----------------NKYTQEFVNFIRECTVMDPEKRPGPEQLLK--HPFI
    . | .                     |...|| .||. | ..||.||| ..||||  ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 83956.m00144.AA MST 33-290 42 9.5e-85 269.3 In-house 1-254 (254) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-254/254
Sequence Identity: 42% (112 aa)

FKVIRKIGAGGFGDVYEMEHIPSGIHMAGKSVSVEKMTRTSK-THLAREIDLLRKVMSPYTVQYYGSID--FEGSPMILLEFCNRGSLYDIMKAKKMTFS
| .. |.| | .| ||   |. .|.  | | |.|.     .    .  ||  .    |.| |.||||     .    |  |.|. ||. ||||. . |..
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVN-----EDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLN

EDQISVIMKDMITALIILHKNFHVLHRDVKAGNILLNSSCQIKLTDFGISCQFSSTSSQRTQTITGTPYWMAPEIMNDDHYGYPADIWSLGITAVELAEG
|.||..| .|    |  ||.| .  ||| ||||||||     || ||| | | . |   | .|  |||||||||  .   | . ||||||||||.|.|||
EQQIACILYDTLQGLQYLHDN-KKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKR-NTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEG

QPPYSELPYTRALVEISTKGFPGFRKGNKYTQEFVNFIRECTVMDPEKRPGPEQLLKHPFI
 ||||..  .||.  | .|  |.|..  .. ||| .|.. | . .||.|.  ||||.||||
MPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase 83956.m00144.AA S_TKc 33-290 29 3.8e-83 283.46 SMART 1-231 (231) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-231/231
Sequence Identity: 29% (81 aa)

FKVIRKIGAGGFGDVYEMEHIPSGIHMAGKSVSVEKMTRTSKTHLAREIDLLRKVMSPYTVQYYGSIDFEGSPMILLEFCNR--GSLYDIMKAKKM----
....|||| |.|| ||   |. .| ..| | ..          |. |||..|.|   |. |..|....  ..  . .|.|.   |.|.|..| ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

-TFSEDQISVIMKDMITALIILHKNFHVLHRDVKAGNILLNSSCQIKLTDFGISCQFSSTSSQRTQTITGTPYWMAPEIMNDDHYGY-PADIWSLGITAV
  |.| ..  .|. .. ||  .|.. ...|||.|  ||||..  .||..|||...|.         |. |||..||||..   .||. ..|.||.|..  
FPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELAEGQPPYSELPYTRALVEISTKGFPGFRKGNKYTQEFVNFIRECTVMDPEKRPGPEQLLK-------HPFI
|.. |.||..   . . .  |              ..|. .||| | ..||||||.  ..|.       ||..
EMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 83956.m00144.AA PAKL 33-290 40 1.2e-81 277.54 In-house 1-256 (256) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-256/256
Sequence Identity: 40% (106 aa)

FKVIRKIGAGGFGDVYEMEHIPSGIHMAGKSVSVEKMTRT-SKTHLAREIDLLRKVMSPYTVQYYGSIDFE-GSPMILLEFCNRGSLYDIMKAKKMTFSE
|    | | |..| ||   |  ..  .| |. .   .. .     .  ||..| |  .|. | |.|||  .     ||...|  ||  |.|.    |. |
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIE---IKESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNE

DQISVIMKDMITALIILHKNFHVLHRDVKAGNILLNSSCQIKLTDFGISCQFSSTSS-QRTQTITGTPYWMAPEIMNDDHYGYPADIWSLGITAVELAEG
 ||||| .     |. ||    . |||.|| |||||  ||.|. |||.| |  .. . |  | | ||||||||||.|   | . .|||||||||.|.|.|
KQISVILQQTLKGLHYLHSK-NIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMI-GTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADG

QPPYSELPYTRALVEISTKGFPGFRKGNKYTQEFVNFIRECTVMDPEKRPGPEQLLKHPFI
 || ...| .||...|  .  | | .  ..  .|..|.  | | |||||. | .|| ||||
FPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase 83956.m00144.AA YSK 77-290 40 3.5e-72 216.51 In-house 44-257 (257) Show / Hide 
Range on Protein: 77-290
Range on HMM: 44-257/257
Sequence Identity: 40% (89 aa)

LAREIDLLRKVMSPYTVQYYGSIDFEGSPM-ILLEFCNRGSLYDIMKAK-KMTFSEDQISVIMKDMITALIILHKNFHVLHRDVKAGNILLNSSCQIKLT
...||  |    |||  .||||   ... . |  |.|  ||. | ||.|    | | .|..|..  . .|  ||..  ..|||.|| |.||. . ..|| 
IQQEIQFLSQCDSPYITKYYGSY-LKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKYIAIILREILKGLDYLHSE-RKIHRDIKAANVLLSEHGDVKLC

DFGISCQFSSTSSQRTQTITGTPYWMAPEIMND--DHYGYPADIWSLGITAVELAEGQPPYSELPYTRALVEISTKGFPGFRKGNKYTQEFVNFIRECTV
|||.. |   |.  | .|  |||||||||.     . | . |||||||||| |.| |.|||...   |..  |  |  |   .|..|.  | .|.  | .
DFGVAGQITDTQIKR-NTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPPYCDYHPMRVMFLI-PKNNPPKLEGRSYSKMFKEFVECCLN

MDPEKRPGPEQLLKHPFI
 |||.||  ..|||| ||
KDPEQRPSAKELLKHKFI
Kinase 83956.m00144.AA Pkinase 33-290 26 4.1e-72 250.69 Pfam 1-293 (293) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-293/293
Sequence Identity: 26% (78 aa)

FKVIRKIGAGGFGDVYEMEHIPSGIHMAGKSVSVEKMTRTSKTHLAR--EIDLLRKVMSPYTVQYYGSIDFEGSPMILLEFCNRG----SLYDIMK---A
....||||.|.|| ||.  |. .|.  | | .....     . ...|  || ..... .|. |..|..   .... . .|.|. |    .|.|...    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KKMTFSEDQISVIMKDMITALIILHKNFHVLHRDVKAGNILLNSSCQI----KLTDFGISCQFSSTSSQRTQTITGTPYWMAPEIMN-DDHYGYPADIWS
....|||...  .|. .. .|  .|..  ..|||.|  |||... ..|    |..|||...||.  ... ..|..|||..||||. . . .||...|.||
GCFYFSEWECKFYMYQILRGLEYCHSM-GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGITAVELAEGQPPYSEL----PYTRALVEISTKGFPGFRKGNKYT---------------------QEFVNFIRECTVMDPEKRPGPEQLLKHPFI
.|..  |.. |.||...     .  . .. |  .. | ..    ..                     .|.  ||. |  .||.|||..||.|.||..
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 83956.m00144.AA SLK 33-290 35 3.4e-67 225.7 In-house 1-259 (259) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-259/259
Sequence Identity: 35% (93 aa)

FKVIRKIGAGGFGDVYEMEHIPSGIHMAGKSVSVEKMTRTSKTHLAREIDLLRKVMSPYTVQYYGSIDFEGSPMILLEFCNRGSLYDIMKAKKMTFSEDQ
...|  .| | || ||  .|   ..  | |.. ...    .  ..  |||.| ..  |. |. |..  ...  ....|||. | .  ||   . .  |||
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELED-YMV-EIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQ

ISVIMKDMITALIILHKNFHVLHRDVKAGNILLNSSCQIKLTDFGISCQFSSTSSQRTQTITGTPYWMAPEIM-----NDDHYGYPADIWSLGITAVELA
| .. | |. ||  ||.| .|.|||.||||||.    ...| |||.| .  .|  |.  |  |||||||||..      |. | | ||||||||| .|.|
IQYVCKHMCEALNWLHSN-KVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHT-MQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMA

EGQPPYSELPYTRALVEISTKGFPGFRKGNKYTQEFVNFIRECTVMDPEKRPGPEQLLKHPFI
.. ||..|.   | |. |     |   .  ....|| .|...| | ||..|.  .||..|...
QMEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase 83956.m00144.AA PAKA 33-290 32 1.2e-63 217.8 In-house 1-260 (260) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-260/260
Sequence Identity: 32% (87 aa)

FKVIRKIGAGGFGDVYEMEHIPSGIH--MAGKSVSVEKMTRTSKTHLAREIDLLRKVMSPYTVQYYGSIDFEGSPMILLEFCNRGSLYDIMKAKKM----
.|.. ||| |. | ||. . |  .     | |   ...    .|  .  || ....   .  |.|. |  ..    . .|. . |.| |. ..       
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKN--QPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCN

TFSEDQISVIMKDMITALIILHKNFHVLHRDVKAGNILLNSSCQIKLTDFGISCQFSSTSSQRTQTITGTPYWMAPEIMNDDHYGYPADIWSLGITAVEL
...|.||. . .  . .|  .|.. |. |||.|  ||||..  ..|.||||   | .   ..|. |. |||||||||. .   |..  ||||||| | |.
YMDEGQIAYVCRECLQGLEFIHSK-HRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRN-TMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEM

AEGQPPYSELPYTRALVEISTKGFPGFRKGNKYTQEFVNFIRECTVMDPEKRPGPEQLLKHPFI
.||.||| . |  ||.  |.|.| | ..  .| .||| .|   |  .|...|.  ..||.|||.
IEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase 83956.m00144.AA KHS 33-290 36 2.4e-60 201.66 In-house 1-258 (258) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-258/258
Sequence Identity: 36% (95 aa)

FKVIRKIGAGGFGDVYEMEHIPSGIHMAGKSVSVEKMTRTSKTHLAREIDLLRKVMSPYTVQYYGSIDFEGSPMILLEFCNRGSLYDIMKAKKMTFSEDQ
. .. ..|.| .||||   .| |.   | | . .|     .   . .|| ....   |  | |.||   .    | .|.|  ||| || ..     || |
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFA--VIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHV-TGPLSELQ

ISVIMKDMITALIILHKNFHVLHRDVKAGNILLNSSCQIKLTDFGISCQFSSTSSQRTQTITGTPYWMAPEIMNDDH---YGYPADIWSLGITAVELAEG
|. . .. ...|  || .   .|||.|  ||||... ..|| |||.| | . | ..|   | |||||||||.   ..   |.   |||..||||.|||| 
IAYVCRETLQGLHYLH-SMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFI-GTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAEL

QPPYSELPYTRALVEISTKGF--PGFRKGNKYTQEFVNFIRECTVMDPEKRPGPEQLLKHPFI
|||  .|   |||  ..  .|  |  .  .|..| | .|.. . . .| ||| .|.||.|||.
QPPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase 83956.m00144.AA MSN 33-290 36 8.1e-59 192.76 In-house 1-265 (265) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-265/265
Sequence Identity: 36% (99 aa)

FKVIRKIGAGGFGDVYEMEHIPSGIHMAGKSVSVEKMTRTSKTHLAREIDLLRK-VMSPYTVQYYGSIDFEGSPM-------ILLEFCNRGSLYDIMK-A
|.... .| | .| ||   |   |   | | ..|..        .  ||..|.|       . |||   .  ||        . .|||  ||. |..| .
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVRE---DEEEEIKQEINMLKKYSHHRNIATYYGAF-IKKSPPGHDHQLWMVMEFCGAGSVTDLVKMT

KKMTFSEDQISVIMKDMITALIILHKNFHVLHRDVKAGNILLNSSCQIKLTDFGISCQFSSTSSQRTQTITGTPYWMAPEIMNDDH-----YGYPADIWS
|  .  || |  | ....  |  ||.. .|.|||.|  |.||  . ..|| |||.| | . |   |  |  |||||||||... |      | | .|.||
KGQSLKEDWIAYICREILRGLAHLHQH-KVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRR-NTFIGTPYWMAPEVIACDENPDATYDYRSDLWS

LGITAVELAEGQPPYSELPYTRALVEISTKGFPGFRKGNKYTQEFVNFIRECTVMDPEKRPGPEQLLKHPFI
.||||.|.||||||  ..   |||. |  .  |  .   |... | ||. .|.. . ..||  ||.||||||
VGITAIEMAEGQPPLCDMHPMRALFLIPRNPPPKLK-SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase 83956.m00144.AA Ste20-DD1 77-290 41 2.6e-53 181.01 In-house 52-268 (268) Show / Hide 
Range on Protein: 77-290
Range on HMM: 52-268/268
Sequence Identity: 41% (90 aa)

LAREIDLLRKVMS-PYTVQYYGSIDFEGSPMILLEFCNRGSLYDIMKAKKMTFSEDQISVIMKDMITALIILHKNFHVLHRDVKAGNILLNSSCQIKLTD
| .||| |.  |  || |.| |    |   || .|.|  ||. |||.    .  |.||  |.   .  |. || |  ..|||.||||.|.|   | || |
LKKEIDILKNTMDCPYIVKYHGCYIKENMLMIVMEYCDGGSILDIMQMCSKRLIEEQIAAICYQIVKGLVYLHSN-RITHRDIKAGNVLVNKEGQPKLAD

FGISCQFSSTSSQRTQTITGTPYWMAPEIMND----DHYGYPADIWSLGITAVELAEGQPPYSELPYTRALVEISTKGFPGFRKGNKYTQEFVNFIRECT
||.|     .  .. .|. | ||||.|||       . |   ||||||||||.|.||  ||  ...  |    |  .  |  .       ||  ||. | 
FGVSTIAVNQ-GFKMNTVIGSPYWMSPEIIMPPKGSQGYDQKADIWSLGITAIEMAESKPPRFNVNPVRVIFVIPHQQPPTLKIPSNWSPEFNDFIKQCL

VMDPEKRPGPEQLLKHPFI
 |.|.|||   ||| ||||
NMNPDKRPSAQQLLNHPFI
Kinase 83956.m00144.AA TyrKc 33-290 20 2.3e-15 25.75 SMART 1-280 (280) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

FKVIRKIGAGGFGDVYEMEHIPSGIHMAGKSVSVEKMTRTSKTHLAREIDLLRKV--MSPYTVQYYGSIDFE-------GSPMILLEFCNRGSLYDIMKA
 . ..|.| | || ||. . .   |  | |..  ..     .  . ||. ...|.    |  |. || .  .       . .||..|..  |.| |  ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KKMTFSEDQISVIMKDMITALIILHKNFHVLHRDVKAGNILLNSSCQIKLTDFGISCQFSST-------SSQRT----QTIT-GTPYWMAPEIMNDDHYG
.. ... ..   .. .       ||.. .. |||  | |.|...  ..| .||| |    .        .  |.    .. |     ||||| .|.  . 
HRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

YPADIWSLGITAVELAE-GQPPYSE-----LPYTRALVEISTKGFPGFRKGNK------YTQEFVNFIRECTVMDPEKRPGPEQLLKHPFI
   |.|| |..  |.   ||.||..     .. ....  . . . .   . .        ..|  . ...|   |||.||  ...  | ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 83956.m00144.AA Pkinase_Tyr 152-237 28 1.2e-08 29.94 Pfam 131-220 (270) Show / Hide 
Range on Protein: 152-237
Range on HMM: 131-220/270
Sequence Identity: 28% (26 aa)

HVLHRDVKAGNILLNSSCQIKLTDFGISCQFSSTSSQ-RTQTITGTPY-WMAPEIMNDDHYGYPADIWSLGITAVELAE-GQPP-YSELP
.  |||. | |.|.... ..| .||| .    ...   |... .  |  ||||| .|.  .    |.|| |..  |.   |. | | ...
NCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMS
Kinase 83956.m00144.AA Pkinase_Tyr 33-132 20 0.00045 14.42 Pfam 1-112 (270) Show / Hide 
Range on Protein: 33-132
Range on HMM: 1-112/270
Sequence Identity: 20% (23 aa)

FKVIRKIGAGGFGDVYEMEHI----PSGIHMAGKSVSVEKMTRTS--KTHLAREIDLLRKV-MSPYTVQYYGSID-FEGS--PMILLEFCNRGSLYDIMK
 . ..|.|.| ||.||. .        .|. | |..  |. .     .  . ||. ....    |  |..|| .   ...  ..| .|..  |.|.|  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

AK---KMTFSEDQ
..   |  ..  .
KHREDKQPLTMKD
Kinase 83956.m00144.AA YSK 33-48 50 0.003319 5.1 In-house 1-16 (257) Show / Hide 
Range on Protein: 33-48
Range on HMM: 1-16/257
Sequence Identity: 50% (8 aa)

FKVIRKIGAGGFGDVY
|.   .|| | ||.||
FTKQECIGRGSFGEVY
Kinase 83956.m00144.AA Ste20-DD1 33-47 46 0.149851 0.84 In-house 1-15 (268) Show / Hide 
Range on Protein: 33-47
Range on HMM: 1-15/268
Sequence Identity: 46% (7 aa)

FKVIRKIGAGGFGDV
|...  || | || |
FQIVEVIGQGSFGVV