Gene 140657.m00003 (T.vaginalis)
140657.m00003
Species: T.vaginalis
Alias: TvagK0893, 140657.m00003
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 140657.m00003.AA | Protein | None | 554 | None | Fasta, JSON |
| 140657.m00003.kin_dom | Protein Kinase Domain | None | 274 | None | Fasta, JSON |
Protein domains of 140657.m00003.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 140657.m00003.AA | AGC | 146-419 | 30 | 1.4e-147 | 384.46 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 146-419
Range on HMM: 1-395/395
Sequence Identity: 30% (122 aa)
FNFLKRISSGAYARVFLAQKK------KTGDLYAIKVLKRKE---CEQKNQFKRVLAE------------KDILLQFS----------NPYIVK-FYYSI
|.||| |. |.. .|.|..|| ||..||.|||| |. . .||. .....| ..|| . . .|.||| .||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF
IGHHN--LYLVMEYLP---------GG-DLYSLLQ---NVGCLDEENTRIYALQ-------ILSALHTLHK-SGIIHRD-LKPDNILIGADGLLKLTDFG
. ||.||||.| || .|.. || . |..||| .|.|| . |..||. ||. |||||| |||.|||. .|| .||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG
LSHLGVVGR-------------------------QNNTDKNSQAPVEDPSLN-----------TAASLVG--TPDYIAPEILLNQPHTFTADYWS--LGV
|. |. .. . |. .| . .. . .. ...| ||.|.||||| .....|.|| ||.
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDT-NK-CNPNNWQRNN-MSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGC
IIYELLCGEPPFHGET----------ETETHTNIL------RGKIDFTD---------MDLQPEIEDFIRRLLTIDPKNRLGSKS-------FEEITNHP
..||.|.| |||.|.. . |.. .|. |. | . . || |.|..||. ||..|||.. .||| |||
LMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHP
WL
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WF
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| Kinase | 140657.m00003.AA | MAST | 146-419 | 34 | 4.5e-117 | 359.34 | In-house | 1-337 (337) | Show / Hide |
Range on Protein: 146-419
Range on HMM: 1-337/337
Sequence Identity: 34% (115 aa)
FNFLKRISSGAYARVFLAQKKKTGDLYAIKVLKRKECEQKNQFKRVLAEKDILLQFSNPYIVKFYYSIIG--HHNLYLVMEYLPGGDLYSLLQNVG-CLD
|.|.| || ||| .|.|...|||.|..|.||.. ||| . | .|..|| . .||..||..|| |..||||. ||| |||...| |..
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP
EENTRIYALQILSALHTLHKSGIIHRDLKPDNILIGADGLLKLTDFGLSHLGVVGRQNNTDKN--------------SQAPVEDPSLN------------
|. ...| .. .| ||..||.||||||||.|| ..| .|||||||| | .....|... . .. . . .
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTNKN
-----------------------TAASLVGTPDYIAPEILLNQP-HTFTADYWSLGVIIYELLCGEPPFHGETETE-THTNILR--GKIDFTDM------
. .|||||||||..| |. . ..|.||.|.|.||.|.|.||| |.| | . ||. .| . .
QIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDD
-DLQPEIEDFIRRLLTIDPKNRLGSKSFEEITNHPWL
..|| | |..||. .|| |||.. .|| .||
DCMSPEAQDLIKKLLQPNPKKRLGANGADEIKQHPFF
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| Kinase | 140657.m00003.AA | MAST | 146-419 | 34 | 1.1e-113 | 367.96 | In-house | 1-334 (334) | Show / Hide |
Range on Protein: 146-419
Range on HMM: 1-334/334
Sequence Identity: 34% (116 aa)
FNFLKRISSGAYARVFLAQKKKTGDLYAIKVLKRKECEQKNQFKRVLAEKDILLQFSNPYIVKFYYSIIGHHNLYLVMEYLPGGDLYSLLQNVGCLDEEN
|.| | || ||| .|.|. .|||.|..|.||.| . ||. . | .|..|| . .||..||..|| .|..||||. |||. |||...|..||.
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM
TRIYALQILSALHTLHKSGIIHRDLKPDNILIGADGLLKLTDFGLSHLGVVGRQNNTDKN--------------SQAPVEDPSLNT--------------
...| .. .| ||..||.||||||||.|| ..| |||||||| | . ..|..... . .. .. .
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ
--------------------AASLVGTPDYIAPEILLNQP-HTFTADYWSLGVIIYELLCGEPPFHGETETETHTNILRGK---IDF--T-----DMDLQ
...|||||||||..|.|. | . |.||.|.|.||.|.| ||| ..| .|. ||| . | . . | ..
QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS
PEIEDFIRRLLTIDPKNRLGSK-SFEEITNHPWL
|| | |..||. ||. |||.. .|. .|| .
PEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
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| Kinase | 140657.m00003.AA | S_TKc | 146-419 | 32 | 1.6e-98 | 334.5 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 146-419 Range on HMM: 1-231/231 Sequence Identity: 32% (93 aa) FNFLKRISSGAYARVFLAQKKKTGDLYAIKVLKRKECEQKNQFKRVLAEKDILLQFSNPYIVKFYYSIIGHHNLYLVMEYLPG--GDLYSLLQNVGC--- . .|. | .||...|.....|||| ..|||..| .... | .|| . |.|||.|... ..||.||||..| |||...... |. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---LDEENTRIYALQILSALHTLHKSGIIHRDLKPDNILIGADGLLKLTDFGLSHLGVVGRQNNTDKNSQAPVEDPSLNTAASLVGTPDYIAPEILLNQP ..| .| |. ||..|| .|. |||||||||.|||. .|..||||. . ...|||.|.|||.| . RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------TTFCGTPWYMAPEVL---G HTF-TADYWSLGVIIYELLCGEPPFHGETETETHTNILRGKIDFTDMDLQPEIEDFIRRLLTIDPKNRLGSKSFEE----ITNHPWL ... .| ||.|.|.||.|||.|||. .. .. .|. || ||||..|. ||..|.. . | .|||. YGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 140657.m00003.AA | AktR | 146-419 | 34 | 1.5e-93 | 317.1 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 146-419 Range on HMM: 1-268/268 Sequence Identity: 34% (98 aa) FNFLKRISSGAYARVFLAQKK-KTGDLYAIKVLKRKECEQKNQFKRVLAEKDILL-QFSNPYIVKFYYSIIGHHNLYLVMEYLPGGDLYSLLQNVGCLDE | ..| . .||...|.|.||| .....||.|..| |. ...||..... |..|. . ..| |||..|.. .|...||| |||.|.. |.. . ..| FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE ENTRIYALQILSALHTLHKS-GIIHRDLKPDNILIGADGLLKLTDFGLSHLGVVGRQNNTDKNSQAPVEDP--SLNTAASLVGTPDYIAPEILLN-QPHT | .|.|. ||| || .||. || |||||.|||.. || .|.|||||| . .| |..||| |.|||.... ..|. EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-----------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHN FTADYWSLGVIIYELLCGEPPFHGETETETHTNILRGK-IDFTD-MDLQPEIEDFIR-RLLTIDPKNRLG--SKSFEEITNHPWL ...|.|..|. |||.. | ||| . .. .|. . |.. ... .. |.| .|| .|..||| ....||| .||| KSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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| Kinase | 140657.m00003.AA | Ciliate-E2 | 146-419 | 27 | 2.4e-90 | 306.48 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 146-419 Range on HMM: 1-365/365 Sequence Identity: 27% (104 aa) FNFLKRISSGAYARVFLAQKKKTGD-----------------------LYAIKVLKRKECEQKNQFKRVL----------AEKDILLQFSNPYIVKFYYS ..|.| | .|... |......|.. .||.|..| .. ||..| .... || || | ..|.|.|.|.. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC II--GHHNLYLVMEYLPGGDLYSLLQNV-----------GCLDEENTRIYALQILS---------------ALHTLHKSG-IIHRDLKPDNILIGADGLL . .|.||||||. ||||.....| ....|. . . |||. ||. ||. . |||||.||.|||. . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KLTDFGLSHLGVVGRQNNTDKNSQA-PVEDPSL---------------NTAASLVGTPDYIAPEILLNQP---------HTFTADYWSLGVIIYELLCGE |..||||| .||.|. ..|. . . |.. ...||| | ||||| ... ... .|.||||||.||.|.|. KIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK PPFHGETETETHTNILRGKIDFT-----------------DMDLQPEIEDFIRR----LLTIDPKNRLGSKSFEEITNHPWL ||| .|. .|||| .. .| |.|.. .| ||..|.. ..|.| ||||. PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF |
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| Kinase | 140657.m00003.AA | RSK | 149-419 | 35 | 1.8e-85 | 290.24 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 149-419 Range on HMM: 1-278/278 Sequence Identity: 35% (104 aa) LKRISSGAYARVFLAQKK---KTGDLYAIKVLKRKECEQKNQ-FKRVLAEKDILLQFS-NPYIVKFYYSIIGHHNLYLVMEYLPGGDLYSLLQNVGC--- || |.| ||| .|. .|| .|| ||||... |.. .....| .||. | ||. .|. |||.|||..||.|. ||. .. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC LDEENTRIYALQILSALHTLHKSGIIHRDLKPDNILIGA---DGLLKLTDFGLSHLGVVGRQNNTDKNSQAPVEDPS-LNTAASLVGTPDYIAPEILL-- ..|. ..|. .| .|. ||. |||||||||.||| .| .||||||.. .. ... . . . ..| .|.|||.| FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-----------------RCDHNQWTMTFCYTIEYMAPEMLKRA -NQP-HTFTADYWSLGVIIYELLCGEPPFHG---ETETETHTNILRGKIDFTDM---DLQPEIEDFIRRLLTIDPKNRLG--SKSFEEITNHPWL | |. .|.|||||..||.| | |||.| .. |. ..|..||...| . | .| |.||..|. ||..||| . ||| .|||. NQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 140657.m00003.AA | CAMK | 151-419 | 21 | 4.2e-84 | 270.78 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 151-419
Range on HMM: 1-425/425
Sequence Identity: 21% (96 aa)
RISSGAYARVFLAQKKKTG------------DLYAIKVLKRKECEQKN-------------------------QFKRVLAEKDILLQ-------FSNPYI
. .|... |.|.. |.|. .|||....| |. |.|. | .|. . . | |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VKFYYSIIGHHN-------------------LYLVM---EYLPGG----DLYSLLQNVGC---------------LDEENTRIYALQILSALHTLHKSGI
.|.| . .|. .|.|| || .|| ||.. .. || ..|. .| | ||.||.| .|. .|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
IHRDLKPDNILIGAD-----------------GLLKLTDFGLS--HLG---------VVGRQNNTDKNSQAPVEDPSLNTAAS------------LVGTP
.||||||.|||. . . .|..|||.. . . |.. .. . .|||
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HN---------------QWTTPTEGQKMKTFCGTP
DYIA-PEILLN--------------QPHTFTADYWSLGVIIYELLCGEPPFHGE-------------TETETHTNILRGKIDFTDMDLQP----------
|.| ||.|. ..... .| ||.||| | .|||.||| |. .. |.. .|..|| || . . |
EYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWW
-------------EIEDFIRRLLTIDPKNRLGSKSFEEITNHPWL
| |.||..|. ||..|. . |.. ||||.
DDISDEFHHFVSQECKDLIRKMLQVDPEKRM---TIEQCLNHPWM
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| Kinase | 140657.m00003.AA | Pkinase | 146-419 | 29 | 3.8e-82 | 284.03 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 146-419 Range on HMM: 1-293/293 Sequence Identity: 29% (92 aa) FNFLKRISSGAYARVFLAQKKKTGDLYAIKVLKRKECEQKNQFKRVLA--EKDILLQFSNPYIVKFYYSIIGHHNLYLVMEYLPGG----DLYSLLQ--N . ....| ||....|.....|.||...|.|..|.. | ... .. . | |.. .. |.||..|.. . ..|.||||..|| ||..... . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR VGCL--DEENTRIYALQILSALHTLHKSGIIHRDLKPDNILIGADGLL----KLTDFGLSHLGVVGRQNNTDKNSQAPVEDPSLNTAASLVGTPDYIAPE ||. .|. . |..|||..| .|. |||||||||.|||| .| . |..||||. . . .. . ...|||.|.||| HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---------------Y-NNS--MTTFCGTPWYMAPE ILL-NQPHTFTADYWSLGVIIYELLCGEPPFHGE------TETETHTNILRGKIDFTDMDLQ--------------------PEIEDFIRRLLTIDPKNR ... .|... .| ||.|.|.||.|||.||| |. .. . . .|......| . .| |||...|. ||| | VIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKR LGSKSFEEITNHPWL .. .|.| .|||. PT---AEQILQHPWF |
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| Kinase | 140657.m00003.AA | NDR | 146-304 | 43 | 1.2e-72 | 223.16 | In-house | 1-164 (350) | Show / Hide |
Range on Protein: 146-304 Range on HMM: 1-164/350 Sequence Identity: 43% (72 aa) FNFLKRISSGAYARVFLAQKKKTGDLYAIKVLKRKECEQKNQFKRVLAEKDILLQFS--NPYIVKFYYSIIGHHNLYLVMEYLPGGDLYS---LLQNVGC | ..| |..||. .|.|..||.||..||.|... .| .||| . |.||.||. . . ||..|| ||| . .|||||||.||||. . ||.. .. FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI LDEENTRIYALQILSALHTLHKSGIIHRDLKPDNILIGADGLLKLTDFGLSHLGVVGRQNNTDK ..|. .| | . |.. .|| |.||||.||||.|| .|| .|||||||. |. .| .. | FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNK |
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| Kinase | 140657.m00003.AA | Akt | 146-291 | 43 | 2.4e-60 | 191.59 | In-house | 1-148 (264) | Show / Hide |
Range on Protein: 146-291 Range on HMM: 1-148/264 Sequence Identity: 43% (64 aa) FNFLKRISSGAYARVFLAQKKKTGDLY-AIKVLKRKECEQKNQFKRVLAEKDILLQFSNPYIVKFYYSIIGHHNLYLVMEYLPGGDLYSLLQNVGCLDEE |.||| . .|....|||..||.|...| |.|||| . ..||||.. ...|. || .|.||. .|| ...||.||.| .||.|...|| . .|. FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED NTRIYALQILSALHTLHKSGIIHRD-LKPDNILIGADGLLKLTDFGLS .| |. .| .|. ||...|| || ||| |||. .|| ..||||||. RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLC |
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| Kinase | 140657.m00003.AA | PKA | 146-289 | 41 | 8.1e-51 | 175.15 | In-house | 1-146 (263) | Show / Hide |
Range on Protein: 146-289 Range on HMM: 1-146/263 Sequence Identity: 41% (61 aa) FNFLKRISSGAYARVFLAQKKKTGDLYAIKVLKRKECEQKNQFKRVLAEKDILLQFSNPYIV-KFYYSIIGHHNLYLVMEYLPGGDLYSLLQNVGCLDEE |.... . .| ..|| |...|..|. ||.|.||. | . .| .|. || ||.. ..|.|| | |.. .||.|||| |||.. | |...|.... FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP NTRIYAL-QILSALHTLHKSGIIHRDLKPDNILIGADGLLKLTDFG ...|| || .|| ||. ||.||||| |||| .| .|.|||| HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFG |
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| Kinase | 140657.m00003.AA | NDR | 320-419 | 42 | 1.1e-46 | 141.59 | In-house | 240-350 (350) | Show / Hide |
Range on Protein: 320-419 Range on HMM: 240-350/350 Sequence Identity: 42% (47 aa) SLVGTPDYIAPEILLN-QPHTFTADYWSLGVIIYELLCGEPPFHGETETETHTNILRGKIDF--------TDMDLQPEIEDFIRRLLTIDPKNRLGSKS- |.||||||.|||.... . ...| |.||||.| ||.|.| |||...| .|| .|.. |. . ... | || .| ||||.. ||..||||. STVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGK -FEEITNHPWL ..|| .||. GVDEIKSHPFF |
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| Kinase | 140657.m00003.AA | Akt | 317-419 | 39 | 3.7e-36 | 113.02 | In-house | 158-264 (264) | Show / Hide |
Range on Protein: 317-419 Range on HMM: 158-264/264 Sequence Identity: 39% (42 aa) TAASLVGTPDYIAPEILLNQPHTFTADYWS-LGVIIYELLCGEPPFHGETETETHTNILRGKIDFTDM-DLQPEIEDFIRRLLTIDPKNRLG--SKSFEE .. .. ||| |.|||||... || ..| |. ||...||..|| |||. . . .|. ... | | ..|| |.|..||. |||.||| .. .| KTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQE ITNHPWL | .|||. IKRHPWF |
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| Kinase | 140657.m00003.AA | PKA | 323-419 | 35 | 1.1e-28 | 101.64 | In-house | 160-263 (263) | Show / Hide |
Range on Protein: 323-419 Range on HMM: 160-263/263 Sequence Identity: 35% (37 aa) GTPDYIAPEILLNQ-PHTFTADYWSLGVIIYELLCGEPPFHGE--TETETHTNILRGKIDFTDMDLQPE--IEDFIRRLLTIDPKNRLGSKSF--EEITN |||.|.||||... .| | |.||..|||.| | ||| . . .. |. |||.| . . . . |.|..||. |.. |.|.... . | | GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKN HPWL |.| HKWF |
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| Kinase | 140657.m00003.AA | Pkinase_Tyr | 146-291 | 28 | 2.6e-20 | 69.42 | Pfam | 1-158 (270) | Show / Hide |
Range on Protein: 146-291 Range on HMM: 1-158/270 Sequence Identity: 28% (46 aa) FNFLKRISSGAYARVFLAQKK----KTGDLYAIKVLKRKECEQKNQ--FKRVLAEKDILLQF-SNPYIVKFYYSII-GHHN--LYLVMEYLPGGDLYSLL |.| . .||. .|... | .|. |.|.| || . | . ..| |. |. ..| ||..| .. .|.|||| |.|||.. | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL QN----VGCLDEENTRIYALQILSALHTLHKSGIIHRDLKPDNILIGADGLLKLTDFGLS .. . |. . ...|| ... |. ..||||| |.|.. .. | .||||. RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA |
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| Kinase | 140657.m00003.AA | TyrKc | 146-419 | 22 | 1.5e-16 | 45.07 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 146-419
Range on HMM: 1-280/280
Sequence Identity: 22% (69 aa)
FNFLKRISSGAYARVFLAQKKKTGDLYAIKVLKRKECEQKNQFKRVLAEKDILLQF--SNPYIVKFYYSIIGH-------HNLYLVMEYLPGGDLYSLLQ
..| . .||. .|.... | |.|.|| . . | |. .. ..| ||..| .. . . |..|||| |.||| . |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR
NVGC-LDEENTRIYALQILSALHTLHKSGIIHRDLKPDNILIGADGLLKLTDFGLSHLGVVG-----RQNNTDK----NSQ--APVEDPSLNTAASLVGT
. . | . ...|| . ||. ..||||| |.|.|... | .||||| . . .. .| .. |.
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR-------------
PDYIAPEILLNQPHTFTADYWSLGVIIYELL-CGEPPFHG-----ETETETHTNILRGKIDFTDMD--------LQPEIEDFIRRLLTIDPKNRLGSKSF
||| . |. | || || ..|.. |..| | . .| . .. .|. . .|. . ... ||..| .|
--WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP---TF
EEITNHPWL
.|| | .
SEI--HECF
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