Gene 82319.m00024 (T.vaginalis)

82319.m00024

Species: T.vaginalis
Alias: 82319.m00024, TvagK0371
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
82319.m00024.AA Protein None 443 None Fasta, JSON
82319.m00024.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 82319.m00024.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 82319.m00024.AA PH 9-105 17 3e-06 28.19 SMART 1-82 (82) Show / Hide 
Range on Protein: 9-105
Range on HMM: 1-82/82
Sequence Identity: 17% (17 aa)

GPIKGVLKKKYGFEGAWKPCFCEFSSGELKIHSGLEDSPVETTIKITPSTVIHIVRDTLPTRFTIELENDKIYMFSTENSQDTNLWVHNLRSETYNG
  ..| |.||      ||.... . .. | ..          .| ..  || . .       |.|   .   | |..|.... . |.. ... ..| 
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDCTVRE-P------CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN
PH 82319.m00024.AA PH 9-103 18 7e-06 23.91 Pfam 1-92 (92) Show / Hide 
Range on Protein: 9-103
Range on HMM: 1-92/92
Sequence Identity: 18% (18 aa)

GPIKGVLKKKYGFEGAWKPCFCEFSSGELKIHSGLEDSPVETTIKITPSTVIHIVRDTLPTRFTIELENDKIYMFSTENSQDTNLWVHNLRSETY
  ..| |.||  . . ||.... . .. | ..     .    .| .   .| ....   |  | |   . . | |..|.... | |.. ..|  .
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDK-YRPKGSIPLSDCQVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR
Kinase 82319.m00024.AA AGC 113-363 27 4.5e-126 327.6 In-house 1-395 (395) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-395/395
Sequence Identity: 27% (108 aa)

FNIISVLGKGKYGKVMLCEKK------GTGEKVAIKSVKKKQ-IQKSQ--NFKAILSE------------RNNLMRTN----------FPFIVR-IKFAF
|... |.||| .|||.|..||      .||.  |.| .|||  |.. .    . ...|            || |.. |           ||||.  ...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTSTK--FYIGMEYIP---------GG-ELYHILYN--H--DINFSDCKLYLAE-------IALSLQYLHS-RGIVYRD-LKLENIMIAADGHIKLVDFG
|. ..   |. |||.|         || ||...|..  .    . . .. |.||       |.| |.|||| .||..|| ||.|||.. .||||||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKDLSISN---------------------------------------------------ETSTFCG--TIHYVAPELILQRPYSYQIDWWA--FGIIAC
|.| .  ..                                                    |.||||  | .|.||| .    |... |||.  .|.. .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EILFGECPFYDANMT----------VEMEKIL------KEPPNFP----------EDGDDVTKDFISKFLIKRPSKRAK----------LEDMIKHPFW
| |.|  |||. |              ..||.      .... ||          .  ..  ||.|.|.| | |.||             |.  .||. 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 82319.m00024.AA S_TKc 113-363 33 5.7e-93 316.1 SMART 1-231 (231) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-231/231
Sequence Identity: 33% (89 aa)

FNIISVLGKGKYGKVMLCEKKGTGEKVAIKSVKKKQIQKSQNFKAILSERNNLMRTNFPFIVRIKFAFQTSTKFYIGMEYIPG--GELYHILYNHD----
. |. ..||| .|||..| .|.||..|||| .|          . |..|.. |.. . |.||... .||. ...|. |||..|  |.|.... ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---INFSDCKLYLAEIALSLQYLHSRGIVYRDLKLENIMIAADGHIKLVDFGLSKDLSISNETSTFCGTIHYVAPELILQRPYSY-QIDWWAFGIIACEI
   ..  ... |...|.. |.|.||.||..|||| |||..    |||. ||||.. |      .||||| .|.|||..   .|..  .|||..|.|  | 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LFGECPFYDANMTVEMEKILKEPPNFPEDGDDVTKDFISKFLIKRPSKRAKLEDMIK-------HPFW
| |. ||.  .| . ..||.          ..  ||||.| | | |.||    .  .       ||. 
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 82319.m00024.AA AktR 113-363 38 5.8e-90 305.19 In-house 1-268 (268) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-268/268
Sequence Identity: 38% (102 aa)

FNIISVLGKGKYGKVMLCEKK-GTGEKVAIKSVKKKQIQKSQNFKAILSERNNLM-RTNFPFIVRIKFAFQTSTKFYIGMEYIPGGELYHILY-NHDINF
| .. .||||..|||.|..||  .....|.|..||| |.. . ..... ||| .    |.||||. ...||| .| .. |||.|||||...|  .. .. 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

SDCKLYLAEIALSLQYLHSR-GIVYRDLKLENIMIAADGHIKLVDFGLSK---DLSISNETSTFCGTIHYVAPELILQ-RPYSYQIDWWAFGIIACEILF
.. . | |.| | |.|||..  |.||||| |||..  |||.|..||||||   . . . .. .|||| .|.||| |..  .. ...|||||||   |...
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GECPFYDANMTVEMEKILKEP---PNFPEDGDDVTKDFIS-KFLIKRPSKRAK-----LEDMIKHPFW
|  |||. | . . .||....   ...|..  .  ||.|  | | |.| || .      |.  .||. 
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 82319.m00024.AA Akt 113-363 39 6.9e-88 281.02 In-house 1-264 (264) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-264/264
Sequence Identity: 39% (104 aa)

FNIISVLGKGKYGKVMLCEKKGTGEKV-AIKSVKKKQIQKSQNFKAILSERNNLMRTNFPFIVRIKFAFQTSTKFYIGMEYIPGGELYHILYNHDINFS-
|... ||||| .|||.|..|| |..   |.|. ||..|..   .. .. ||| | ..|.||||  ...|||..| |. |.|..||||.  |. ..  || 
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQ-RKRRFSE

-DCKLYLAEIALSLQYLHSRGIVYRD-LKLENIMIAADGHIKLVDFGLSKDLSISN--ETSTFCGTIHYVAPELILQRPYSYQIDWWA-FGIIACEILFG
   . | ||| | ...|||..|.||| ||.|||.. .||||.| ||||.|.  |..  .| |||||  | ||| ...  .. . |||. .|..  | ..|
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

ECPFYDANMTVEMEKILKEPPNFP--EDGDDVTKDFISKFLIKRPSKR----AK-LEDMIKHPFW
  |||. .  . ..||. .| .||  .  ..  ||.||. | | |.||     . ...   ||. 
RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 82319.m00024.AA RSK 116-363 37 7.7e-84 284.84 In-house 1-278 (278) Show / Hide 
Range on Protein: 116-363
Range on HMM: 1-278/278
Sequence Identity: 37% (104 aa)

ISVLGKGKYGKVMLCEKK---GTGEKVAIKSVKKKQIQKSQN-FKAILSERNNLMRTN-FPFIVRIKFAFQTSTKFYIGMEYIPGGELYHILYNHDI---
..|||.| |||| || |.    ||   | | .||. | ..|   .  . ||| |.|..  ||||. . |||| .|.|. |||..||||.  |... .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

-NFSDCKLYLAEIALSLQYLHSRGIVYRDLKLENIMIAA---DGHIKLVDFGLSKDLSIS-NE-TSTFCGTIHYVAPELIL---QRP-YSYQIDWWAFGI
   .... |.|||.| ...||..||..||||.|||. .    .|||||.|||..| .... |. | |||.||.|.|||..    |.  .. . ||| .|.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

IACEILFGECPFYD---ANMTVEMEKILKEP--PNFP--EDGDDVTKDFISKFLIKRPSKRAK-----LEDMIKHPFW
.  | |.|  ||.    .|  . |..|.|    ...|  .   .  ||.|.| | . |.|| .     .|.  .||..
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 82319.m00024.AA SGK 113-363 34 8.5e-82 252.3 In-house 1-283 (283) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-283/283
Sequence Identity: 34% (97 aa)

FNIISVLGKGKYGKVMLCEKKGT------------------GEKVAIKSVKKKQIQ-------KSQNFKAILSERNNLMRT-NFPFIVRIKFAFQTSTKF
| ...|.||| .|||.. ..|..                  . . |.|  .|..|        |    | |..|||...   . ||||  ..|||| .| 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YIGMEYIPGGEL-YHILYNHDINFSDCKLYLAEIALSLQYLHSRGIVYRDLKLENIMIAADGHIKLVDFGLSK-DLSISNETSTFCGTIHYVAPELILQR
|  |.|. |||. ||.        .  . | |||.. | ||||  |.||||| |||.  ..||..| ||||.| .   ...|.|||||  | ||| .. .
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYSYQIDWWAFGIIACEILFGECPFYDANMTVEMEKILKEPPNFPEDGDDVTKDFISKFLIKRPSKR--AK--LEDMIKHPFW
|..   |||  |..  | ..|  |||. |     ..|...| ..|       .| |   | | |.||  .|   ..  .||| 
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 82319.m00024.AA Pkinase 113-363 31 1.7e-79 275.2 Pfam 1-293 (293) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-293/293
Sequence Identity: 31% (94 aa)

FNIISVLGKGKYGKVMLCEKKGTGEKVAIKSVKKKQIQKSQNFKAIL-SERNNLMRTNFPFIVRIKFAFQTSTKFYIGMEYIPGG----ELYHILY---N
. |....|.| .|.| .| .||||..||.| .||. . ....  ... ||   . | | |.|||.. .|..... |. ||| .||    .|....    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

HDI--NFSDCKLYLAEIALSLQYLHSRGIVYRDLKLENIMIAADGHI----KLVDFGLSKDL-SISNETSTFCGTIHYVAPELIL-QRPYSYQIDWWAFG
  .     .|| |. .|.  |.|.||.||..||||.|||.|  .|||    |. ||||.| .   .|...|||||..|.|||.|. ...|.. .|.|..|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG

IIACEILFGECPFYDA------NMTVEMEKILKEPPNFPEDGD---------------------DVTKDFISKFLIKRPSKRAKLEDMIKHPFW
.|  | |.|. ||...      .. . ...|.. |. |... .                     .  ||||.. | | |.||   |.  .||..
CILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 82319.m00024.AA Ciliate-E2 113-363 23 2.7e-79 269.72 In-house 1-365 (365) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-365/365
Sequence Identity: 23% (87 aa)

FNIISVLGKGKYGKVMLCEKKGTGEK-----------------------VAIKSVKKKQIQKSQNFKAIL----------SERNNLMRTNFPFIVRIKFA
...| ..|.| .|.| .|... ....                       .|.|..||.||.   . . |.           |.|.| . |.|.|.... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--TSTKFYIGMEYIPGGELYHILYNHDINF------------SDCKLYLAEIAL---------------SLQYLHSRG-IVYRDLKLENIMIAADGHI
||  . ...|. |||. ||.|.....|.....              .| . ..|.                 |.||||.. |..||.|.|||..     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLVDFGLSKDLSISNE--------------------------------TSTFCGTIHYVAPELILQRP---------YSYQIDWWAFGIIACEILFGECP
|..||||||.....|.                                . |.||| .|.||| .   .         |.|..|.|..|.|  | |||. |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FYDANMTVEMEKILKEPPNFP------------------EDGDDVTKDFISK----FLIKRPSKRAK-LEDMIKHPFW
|        ...|.. . .||                  .. .. .||.|.|     | | |.||    |. ..||. 
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 82319.m00024.AA CAMK 118-363 20 1.4e-73 236.3 In-house 1-425 (425) Show / Hide 
Range on Protein: 118-363
Range on HMM: 1-425/425
Sequence Identity: 20% (88 aa)

VLGKGKYGKVMLCEKKGTG------------EKVAIKSVKKKQIQK-------------------------SQNFKAILSERNNLMR-------TNFPFI
.||.| .||| ||. | |.            .||||| ..||....                          .. | ...| . ...        . | |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRIKFAFQ------------TSTK--------FYIGM---EYIPGGELYHILYNHDINF--------------------SDCKLYLAEIALSLQYLHSRG
...  ...            | .|        .|. |   ||..||||.  |... .                      .... |   |.  ..|.||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVYRDLKLENIMIAAD-----------------GHIKLVDFGLSKDLSISN------------------------ETSTFCGTIHYVA-PELILQ-----
|| ||||.|||..  .                 . ||..|||... .  ..                          .||||| .|.| ||....     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------RPYSYQIDWWAFGIIACEILFGECPFYDA-------------NMTVEMEKILKEPPNFPEDGDDV------------------------TK
         ..|....| |. |.|    | |. |||.              |.   .|||.|   .||..  .                          |
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DFISKFLIKRPSKRAKLEDMIKHPFW
|.|.| | . |.||...|.  .||. 
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 82319.m00024.AA CAMKL 113-363 29 1.7e-71 227.35 In-house 1-297 (297) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-297/297
Sequence Identity: 29% (88 aa)

FNIISVLGKGKYGKVMLCEK-KGTGEKVAIKSVKKKQIQKSQNFKA------------ILSERNNLMRTN---FPFIVRIKFAFQTSTK------FYIGM
..|. .|||| .||| |..  . |||||||| ..|| |.. .. |.            |  | . ... |    | |...   ..|...      .|. |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYIPGGE--LYHILYNHD-----INFSDCKLYLAEIALSLQYLHSRGIVYRDLKLENIMIAADG--HIKLVDFGLSKDLS-I----SNETSTFCGTIHYV
||..|||  |.. . .|      .  .... |   |   ..|.||.||| ||.|.|||..  .|   ||..|||.|     .     .  .||||. .| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELILQ--RPYS-YQIDWWAFGIIACEILFGECPFYDA--------NMTVEMEKILKEPPNFPEDGDD-VTKDFISKFLIKRPSKRAKLEDMIKHPFW
|||...   .||  ...| |. |.|   ...|. || |.        |   ...|| .   ..|   .    .|.|.| | . |.||.....  .||. 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 82319.m00024.AA Ciliate-E2-Unclassified 113-363 26 2.5e-71 243.27 In-house 1-352 (352) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-352/352
Sequence Identity: 26% (94 aa)

FNIISVLGKGKYGKVMLCEKKGTGEKV-------AIKSVKKKQIQKSQNFKAILSERNNLM----------------RTNFPFIVRIKFAFQTSTKFYIG
..|| ..|.| .||| .|..| .. ..        |...|.|||....... .. | ||..                  . ||||.  ..||.  ..|| 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYIPGGELYHILYN------------------HDINFSDCK-----LYLAEIALSLQYLHSRG-IVYRDLKLENIMIAADG---HIKLVDFGLSKDLS-
|||..||.|  .. .                  . .    .|      |.|.| . |.|||. . |..||.|.|||..  .|   .||. |||.|| .  
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------ISNETSTFCGTIHYV----APELILQRPYS----YQIDWWAFGIIACEILFGECPFYDANMTV----------------EMEKIL
               ......|||||. |     |||.. .  |.    |..|.|..|.|. |.|||..|||| | .                   ..|.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

KEPPNFPE--------DGDDVTKDFIS----KFLIKRPSKRAKLEDMIKHPFW
. ...||.        . ..  ||||.    | | |.|.||  .|. ..||. 
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 82319.m00024.AA PKC 113-363 37 1.9e-70 227.48 In-house 1-262 (262) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-262/262
Sequence Identity: 37% (97 aa)

FNIISVLGKGKYGKVMLCEKKGTGEKVAIKSVKKKQIQKSQNFKAILSERNNLMR-TNFPFIVRIKFAFQTSTKFYIGMEYIPGGEL-YHILYNHDINFS
|| . ||||| .||||| |.||| |  ||| .||  | .       . |.  |   .. || .     |||  . .  |||. || | .||   .  . .
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

DCKLYLAEIALSLQYLHSRGIVYRDLKLENIMIAADGHIKLVDFGLSKD-LSISNETSTFCGTIHYVAPELILQRPYSYQIDWWAFGIIACEILFGECPF
  . | |||.. ||.||..||.||||||.|... ..||||..|||..|. .   . |||||||  |.||| .   .|.  .||||||.   | . |  ||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YDANMTVEMEKILKEPPNFPEDGDDVTKDFISKFLIKRPSKRAKL--------EDMIKHPFW
   . .   . |... | .| .     .. ...|. | |.||           .|. .||| 
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 82319.m00024.AA Pkinase_Tyr 113-297 26 6.7e-18 61.25 Pfam 1-202 (270) Show / Hide 
Range on Protein: 113-297
Range on HMM: 1-202/270
Sequence Identity: 26% (53 aa)

FNIISVLGKGKYGKVMLCEKK----GTGEKVAIKSVKKKQIQKSQ-NFKAILSERNNLMRT-NFPFIVRIKFAFQ-TSTK--FYIGMEYIPGGELYHILY
  .. .||.| .|.|.... |    .|. .||.|.. | .  ..|   .. ..| . ..   . | |||   .    .     || ||| |.| |.. | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

NH-----DINFSDCKLYLAEIALSLQYLHSRGIVYRDLKLENIMIAADGHIKLVDFGLSKDL-SISNE-TSTFCGT--IHYVAPELILQRPYSYQIDWWA
.|      .. .|   . ..||  ..||.|.... |||   |.... ....|  ||||..|. . ..  ...  |   |   ||| |  . .. . | |.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

FGI
||.
FGV
Kinase 82319.m00024.AA TyrKc 113-363 21 1.5e-16 44.87 SMART 1-280 (280) Show / Hide 
Range on Protein: 113-363
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

FNIISVLGKGKYGKVMLCEKKGTGEKVAIKSVKKKQIQKSQNFKAILSERNNLMRT--NFPFIVRIKFAFQTS-------TKFYIGMEYIPGGELYHILY
   . .|| | .|.|.... |   ..||.|..|.         .....| . ...   . | |||.  .  ..          .| ||| |.| | . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NHD--INFSDCKLYLAEIALSLQYLHSRGIVYRDLKLENIMIAADGHIKLVDFGLSKDLSIS------NETSTF----CGT----IHYVAPELILQRPYS
.|   .. .|   .   ||   .||||.... |||   |.........|  |||||.|.          .. .     .|     |   ||| |  . ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

YQIDWWAFGIIACEIL-FGECPFYDA----NMTVEMEKILKEP--PNFPED--------GDDVTKDFISKFLIKRPSKRAKLEDMIKHPFW
 . | |.||.   ||. .|. | ..         |. . .|.   .  |..          |   . ...     |..|   ..   | ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 82319.m00024.AA S_TK_X 364-422 21 7e-05 18.32 SMART 1-79 (79) Show / Hide 
Range on Protein: 364-422
Range on HMM: 1-79/79
Sequence Identity: 21% (17 aa)

DDLDFNKVLE--KGYKPEFMPKIN----DVK--ENFDKEFTDCPAIDSFCSP-----VNDSK-------LDISGFSFSE
...|..|..   | ..| | |||.    .    .|||.|||.... .. ..|     .. ..       ..  ||... 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF