Gene 85876.m00174 (T.vaginalis)

85876.m00174

Species: T.vaginalis
Alias: 85876.m00174, TvagK0184
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
85876.m00174.AA Protein None 302 None Fasta, JSON
85876.m00174.kin_dom Protein Kinase Domain None 244 None Fasta, JSON

Protein domain

Protein domains of 85876.m00174.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 85876.m00174.AA S_TKc 14-257 24 6.2e-71 242.88 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-231/231
Sequence Identity: 24% (64 aa)

FQFRDVIGCGACGVVYLVYDPLYRREFALKSIKESKFNKNEVDCMKQVDDSNIVRLYNYDYYDGSVYLLMEYCPT---SLDRYIRRKSI------LSHEQ
... ..|| || |.||....    |..|.| ||  .  ..|....|. .  |||.|| . .  ...|. ||||..   .| .||...        ..  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

MIKYATGILKAIRACHHCHVAHLDIKPANFLIDYYDRIRVCDFGFSSIHSDSELDRTCEGSVPFMAPEIIQGKPHDSFKADMWAIGVTFFIMATGVFPWA
  .|.  |..|.  ||  .. | |.||.| |.|   .| .||||.. .       .|. |.  .||||..   ... .|.|.|..|.....|..|  |. 
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP

GDDRKTLCENLQSQPPRMELVHDTHFAGIIKQLLSINPDERPSIDQLLE-------SQLF
  . ... ...           .  .  .|...|  .|..||.. ..|.        . |
--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 85876.m00174.AA Pkinase 14-257 25 4.7e-64 223.9 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-293/293
Sequence Identity: 25% (74 aa)

FQFRDVIGCGACGVVYLVYDPLYRREFALKSIKESKFNK---------NEVDCMKQVDDSNIVRLYNYDYYDGSVYLLMEYCPT-----SLDRYIR--RK
...  .|| |. |.||. ..  .....|.| || .. ..         .|.  || ..  |||||| . ......|. ||||.      .| .||.  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SIL--SHEQMIKYATGILKAIRACHHCHVAHLDIKPANFLIDYYDRI----RVCDFGFSSI--HSDSELDRTCEGSVPFMAPEIIQGKPHDSFKADMWAI
  .  | .. ..|.. ||...  || . . | |.||.|.|||  . |    ..||||..    .  ..   |  |. ..||||.|.| .... |.|||..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVTFFIMATGVFPWAGD-------DRKTLCENLQSQPPRMELVHD--------------------THFAGIIKQLLSINPDERPSIDQLLESQLF
|.....|..| .|. |.       ... .|.... .... .   .                      .  .|| .|  .| .||...|.|..  |
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 85876.m00174.AA CAMK 19-257 17 4.5e-61 195.22 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-257
Range on HMM: 1-425/425
Sequence Identity: 17% (76 aa)

VIGCGACGVVYLVYDPLYR------------REFALKSIK-------------------------------ESKFN--KNEVDCMKQ-------VDDSNI
..| |. |.|.|... .              ...| | |.                               ...    ..|...||.       .|  ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLYN-----------YDYY---------DGSVYLLM---EYCPT-----SLDRYIRRK---------------SILSHEQMIKYATGILKAIRACHHCH
..||             | |         |  .|. |   |||.       |  ||...                 .. ..  .|   |. |.. || ..
IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VAHLDIKPANFLIDYYD-----------------RIRVCDFGFSSIHSDSELDR------------------------TCEGSVPFMA-PEIIQG-----
..|.|.|| | |.|. .                  | ..||||. .  ..| ..                        |. |. ..|| ||...|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KPHDSFKADMWAIGVTFFIMATGVFPWAGD-------------DRKTLCENLQSQPPRMEL-----------------VHDT-------HFA
        || ...|.|||..||  .|| .| .|. ||             . . |.|. ..   ...                  . |           
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

GIIKQLLSINPDERPSIDQLLESQLF
  |...|  .|..|..|.| |. . .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 85876.m00174.AA CAMKL 14-257 25 4.1e-60 190.47 In-house 1-297 (297) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-297/297
Sequence Identity: 25% (77 aa)

FQFRDVIGCGACGVVYLVYDPLY-RREFALKSIK------ESKFNKN--------------EVDCMKQVD---DSNIVRLYNYDYYDGS------VYLLM
... ...|.|..|.| |  . .. ... | | |.      . . .||              |. .||...     ||..||   . .        .|| |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCPTS---LDRYIRRKSI----LSHEQMIKYATGILKAIRACHHCHVAHLDIKPANFLIDYYD--RIRVCDFGFSSIHSD-----SELDRTCEGSVPFM
|||.     |  ||...      .. ..  .| . |. |.  || ....| |||| | |.|. .   | ..||||| .. .      .. .|. || |.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIIQG--KPHDSFKADMWAIGVTFFIMATGVFPWAGDD---------RKTLCENLQSQPPRMELVHDTHFAGIIKQLLSINPDERPSIDQLLESQLF
||||.||  ||.| .|.|.|..||. . | .| .|. .|.         .. . .. .   |.  .  .     .|...|  ||..||.|.|...   .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 85876.m00174.AA Ciliate-E2 14-257 20 1.9e-48 164.41 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-365/365
Sequence Identity: 20% (76 aa)

FQFRDVIGCGACGVVYLVYDPLYRREFALKSIKESK-------------------FNKNEVDCMKQVDDSN-----------------------IVRLYN
. |  .|| |. |.||.. . . ...||.| |.  |                   ..||..  .||... .                       |...| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

YDY--YDGSVYLLMEYCPT-SLDRYIR-----RKSI------LSHEQMIKYATGILK---------------AIRACHHCH-VAHLDIKPANFLIDYYDR
. .   | ..|| ||||   .|  ||.     |...      ......... . ||.               |.. .|  . . | |||| | |.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IRVCDFGFSSIHSDSELDRT----CE----------------------------GSVPFMAPEIIQGKP--------HDSFKADMWAIGVTFFIMATGVF
| ..|||.| . .|.. .||    |.                            |. ..|||||..||.        . ..|.|.|..||....| .| .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PWAGDDRKTLCENLQ--SQPPRME---------------LVHDTHFAGIIKQ----LLSINPDERPS-IDQLLESQLF
|.       . ...|   . |  |               . ..     .||.    .|  .|..|.. ..|.|. . |
PF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 85876.m00174.AA STE 14-257 20 3e-45 156.64 In-house 1-359 (359) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-359/359
Sequence Identity: 20% (76 aa)

FQFRDVIGCGACGVVYLVYDP----LY-----------RREFALKSIK----------------------ESKFNKNEVDCMKQVD--DSNIVRLYNYDY
... ..|| ||.|.||. ..     ..            . .| | ..                      | .  ..|.. ||. .    |||. | . .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

YDG-------SVYLLMEYCP-TSLDRYIRRKSILSH-------------EQMI-KYATGILKAIRACHHCH-VAHLDIKPANFLIDYYDRIRVCDFGFSS
..|       .... |||..  |||  |..| .                |. | ...  |||.. . .| | . | |||||| |.     .  ||||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

IHSD-----------------SELDRTCEGSVPFMAPEIIQG-----KPHDSFKADMWAIGVTFFIMATGVFPWAG-DDRKTLCENLQS-----------
. .|                 ..   |. |.  .||||.||.     ... ..|.|.| .| |   ||||  ||.   . . . . ...           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----QPPRMELVHD-------------------THFAGIIKQLLSINPDERPSIDQLLE--SQLF
    .||. .   .                    .|   |.. | ..|..||. .|||.     .
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 85876.m00174.AA MARK 14-257 29 3.4e-43 139.14 In-house 1-262 (262) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-262/262
Sequence Identity: 29% (78 aa)

FQFRDVIGCGACGVVYLVYDPLYRREFALKSIK---ESKFNK-----NEVDCMKQVDDSNIVRLYNYDY--YDGS-VYLLMEYCP-TSLDRYIRRK--SI
. .  .||.|....|.|. . ...|..|.| ..    .....      |.. ||..|  ||..|. .      .  .|| |||.. ..|  ||. .    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSHEQMIKYATGILKAIRACHHCHVAHLDIKPANFLIDYYD--RIRVCDFGFSSIH-SDSELDRTCEGSVPFMAPEIIQGKPHDSFKADMWAIGVTFFIM
|..|   .. . |. |.  ||  ...| |||| | |||      |  .||||| .  ... |.. | |. |.|||||...|| | .|.|.|. ||  ..|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFC-GTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

ATGVFPWAGDD--RKTLCENLQSQPPRMELVHDTHFAGIIKQLLSINPDERPSIDQLLESQLF
 .| ||. ||.   |.| .. ..  ..      ..   .|..|| .||.|||.|.....   .
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 85876.m00174.AA Ciliate-E2-Unclassified 14-257 20 3.3e-42 144.2 In-house 1-352 (352) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-352/352
Sequence Identity: 20% (71 aa)

FQFRDVIGCGACGVVYLVYD---PLY--------RREFALKSIKES---------KFNKNEVDCMK-----------QVDDSNIVRLYNYDYYDGSVYLL
. .  .|| |. |.||....    .|         .... |.|...          .||.. . ..           . .. .||... ..  .  .|. 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYCP-TSLDRYIR-RKS----------------ILSHEQMI-----KYATGILKAIRACHHCH-VAHLDIKPANFLIDYYD---RIRVCDFGFSS----
||||.  .|  ||. ||.                |.. .|..     .|.  ||...  .|| . . | |||| | |.|      .|...|||.|.    
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

-------------IHSDSELDRTCEGSVPFM----APEIIQGKPHDS---FKADMWAIGVTFFIMATGVFPWAGDDRKT----------------LCENL
             | .. ... .| |.  .|    |||..||. .|    .|.|.|. || .. | .| .|  . ...                 | .| 
NNNCDTNQQQKMQIWKQQMMWTFC-GTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

QSQPPRMELVHD----THFA--------GIIKQLLSINPDERPSIDQLLESQLF
. ...            |           .....|  ||..|....|.|. ..|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 85876.m00174.AA ULK 14-257 23 5.7e-35 119.55 In-house 1-329 (329) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-329/329
Sequence Identity: 23% (76 aa)

FQFRDVIGCGACGVVYLVYDPLYR----REFALKSIK---ESKFN------------KNEVDCMKQVD----DSN----IVRLYNYDYYDGS--VYLLME
.. ....| |. |.||  ..          .| | |    ....|            |||.. ||. .      |    ||.|| . . . .  .|. ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPT-SLDRYIRRK----------SILSHEQMIKYATGILKAIRACHHCHVAHLDIKPANFLIDYYD------------RIRVCDFGFSSI-HSD---SE
||.   |. || ..           .|| .. |..   || . .. |   . | ||||.| ||.  .            .. ..||||.    .|    .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LDRTCE------GSVPFMAPEIIQ----GKPHDSFKADMWAIGVTFFIMATGVFP---WAGDDRK-TLCENLQSQPPRME-------LVHD---------
.  ||       |.  .|||.|.|    .||....|.|.| .|. |. | .|  |   |   | .   ...|  .||...       |  .         
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

THFAGIIKQLLSINPDERPSIDQLLESQLF
  .  .|...| .....| |...|..  .|
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 85876.m00174.AA ULK 14-257 21 2.5e-33 115.66 In-house 1-324 (324) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-324/324
Sequence Identity: 21% (69 aa)

FQFRDVIGCGACG-VVYLVY-DPLY--RREFALKSIK-----ESKFN----------KNEVDCMKQVD---DSN--IVRLYNYDYYDGS--VYLLMEYCP
.. ....| |. | .||  .          .| | |      ..| .          |||.  ||. .     |  ||.|| . . . .  .|. ||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

T-SLDRYIRRK---------SILSHEQMIKYATGILKAIRACHHCHVAHLDIKPANFLIDYYD------------RIRVCDFGFSSI-HSDS---ELDRT
   |. || ..          .|| .. |..   |. . .. |   . | ||||.| ||   .            .. ..||||. .  ...    .  |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

CE------GSVPFMAPEIIQ----GKPHDSFKADMWAIGVTFFIMATGVFPWAGDDRKTLC-------------------ENLQSQPPRMELVH-DTHFA
|       |.  .|||.|.|    .||....|.|.| .|. |. | .|  |. ..   ..                    ...| ..|. . ..    . 
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPP-KDPKISPECK

GIIKQLLSINPDERPSIDQLLESQLF
 .|...| .....| |......  .|
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 85876.m00174.AA CMGC 14-194 17 2.3e-32 102.97 In-house 1-326 (513) Show / Hide 
Range on Protein: 14-194
Range on HMM: 1-326/513
Sequence Identity: 17% (57 aa)

FQFRDVIGCGACGVVYLVYDPL--------------YRREFALKSIKESKFNK-----------------NEVDCMKQV-----------------DDSN
..  ..||.|. ||||  .| .              . .. |.| ||. . ..                  |. ..|..                 .. |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVRLYNYDYYDG-----------------SVYLLMEYCPTSLDRYIRRKS---------ILSHEQ------------MIKYA------TGILKAIR--AC
||.||.. |...                 ..|| .||....| .||....          ||. .              ..         ||...    |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HHCH--VAHLDIKPANFLID--------------------YYDRIRVCDFGFSS-IHSD---------------------SELDRTCEGSVPFMAPEIIQ
|     . | |.||.| ||.                      .|...||||..  .|.                      ..   .   .    ||||. 
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GK---------PHDSFKADMWAIGVTFF
|           | . . |||..|  |.
GWKHYTNHNYSMHYTTPIDMWSVGCIFA
Kinase 85876.m00174.AA TKL 20-255 16 4.4e-30 105.52 In-house 1-364 (364) Show / Hide 
Range on Protein: 20-255
Range on HMM: 1-364/364
Sequence Identity: 16% (60 aa)

IGCGACGVVYLVYDPLYR-----------REFALKSIKES--------------------------------KFNKNEVDCMKQVDDSNIVRLYNYDYYD
|| |. |.||  .   .|           .. | | .|.                                 .| ..|. .|.. .  |||... |. . 
IGSGGFGEVYKGK---WRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCP

GS-------------VYLLMEYC-PTS-LDRYIRRKSILSHEQMIKYATGILKAIRACHHCH--------VAHLDIKPANFLIDYYDR------------
..              .. ||||   | |....       ..|... | .| ...   | ..        ..| |.|..| |.|   .            
PCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--IRVCDFGFSSIHSDSE--------------------LDRTCEGSVPFMAPEIIQGKP---------------HDSFKADMWAIGVTFFIMATGVFPWA
  . .||||.|  .| |.                       |. |.  .||||...|..                 | |.|... |. .. ..|.  |..
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

GDDRK------------TLCENLQSQPPRM-----------ELVHDTHFAGIIKQLLSINPDERPSIDQLLESQ
...               .. . . .||.            .   ..... ....  . .|..||| ...|.  
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 85876.m00174.AA TyrKc 14-257 21 2.2e-13 -6.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

FQFRDVIGCGACGVVYL-VYDPLYRREFALKSIKESKFNK---NEVDCMKQV--DDSNIVRLYNYDYYD-------GSVYLLMEYCPT-SLDRYIRRKSI
 .. ...|.|| |.||. ...    .. | |..||..  .   .|   |...  .  |||||| .   .       . ....|||.|  .|. |.|..  
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-LSHEQMIKYATGILKAIRACHHCHVAHLDIKPANFLIDYYDRIRVCDFGFSSIHSDS-------ELDRT-----CEGSVPF--MAPEIIQGKPHD--SF
 |.......... | .  .  |. .. | |.   | |..   .....||| |  . |        .  |.     . . .|   |||| |    .   ..
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYGKFTT

KADMWAIGVTFF-IMATGVFPWAG-----DDRKTLCENLQSQ--PPRMEL--------VHDTHFAGIIKQLLSINPDERPSIDQLLESQLF
| | |. ||. . |.  |  |. |      . . . |....   .|...          .|  .  |.||    .|..||.  ..   ..|
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF
Kinase 85876.m00174.AA CMGC 234-257 33 2.6e-05 12.4 In-house 490-513 (513) Show / Hide 
Range on Protein: 234-257
Range on HMM: 490-513/513
Sequence Identity: 33% (8 aa)

IKQLLSINPDERPSIDQLLESQLF
.|..| ..||.|....| |.   |
LKKMLQYDPDKRITAEQALQHPYF
Kinase 85876.m00174.AA Pkinase_Tyr 14-112 27 0.000423 14.51 Pfam 1-120 (270) Show / Hide 
Range on Protein: 14-112
Range on HMM: 1-120/270
Sequence Identity: 27% (33 aa)

FQFRDVIGCGACGVVYL-VYD---PLYRREFALKSIKE---------SKFNKNEVDCMKQV-DDSNIVRLYNYDY-YDGS--VYLLMEYCPT-SLDRYIR
 .|  ..| || |.||. ...      . . | |..||          .| . |.  |||  .  ||||||   .  ...  .|. |||.|  .|. | |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

R----KSILSHEQMIKYATGI
.    |  |.......... |
KHREDKQPLTMKDLLQMCWQI