94262.m00256

Species: T.vaginalis
Alias: TvagK0114, 94262.m00256
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1

Sequence

Name Sequence Type Origin Length Description Download
94262.m00256.AA Protein None 345 None Fasta, JSON
94262.m00256.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 94262.m00256.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94262.m00256.AA CAMK1 30-283 39 1.2e-122 358.35 In-house 1-276 (276) Show / Hide
Range on Protein: 30-283
Range on HMM: 1-276/276
Sequence Identity: 39% (110 aa)

FQMEQKLGAGYFAEVFQATGKK---DNKEYAVKVID-RTQAANP-----QRIWAEVQIQL---RLQHPNIIKLYKVFADKYHVALVLEFAKGGELYEHLL
..   ..|.| |.||...| |.   ..|.||.|.|| ... ..      ...  |..|     ...||||||.| .. .. |. ||.|  .|||| .  .
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

DNESYNEIDAASIIKHLLTALVYLHKNGIVHRDIKPENILFADTAAKDP-K--LADFGLSGLLIEGS-LLHSCAGTPIFMAPEVIKA---KGYNYSCDMW
....|.| ||. |.| .| |. |.|..||||||.||||.|..|     . |  .||||||  . ... |.  . ||| ..||||..    |.| ..||||
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW

SVGIMTYLLLCGEVPFNGET-HYDLFKKICSGEFKFIEA-FDSISET-AKDFIKNLIVVDPSKRFSAEKALKHPWI
|.|. || ||||  ||..|. .  ||.|| ..|. |..  .|.||.  ||||||....|||.||...|..|.||||
SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI

Kinase 94262.m00256.AA CAMK 35-283 23 6.6e-110 355.45 In-house 1-425 (425) Show / Hide
Range on Protein: 35-283
Range on HMM: 1-425/425
Sequence Identity: 23% (98 aa)

KLGAGYFAEVFQATGKKDN------------KEYAVKVIDRT----------------------------QAANPQRIWAEVQIQLRLQ-------HPNI
.|| | |..|. .. |...            ...|.|.||..                            .. . ...  |..|  .||       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLYKVFAD-------------------KYHVALVL---EFAKGGEL----YEHLLDNES---------------YNEIDAASIIKHLLTALVYLHKNGI
|||| |. |                   . |. .|.   |.. ||||    .... ....               ..| .|. ... .. |. |.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDIKPENILFADTAA---------------KDPKLADFGLSGLLIE------------------------GSLLHSCAGTPIFMA-PEVIKA------
||||.||||||. |                   . |..|||..  ...                        | ... . ||| .|| |||..       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------KGYNYSCDMWSVGIMTYLLLCGEVPFNGE-------------THYDLFKKICSGEFKFIEAF-------------DSISET--------AKD
        ..|...|||||.|...| .|||. ||.|.             . |.||.||..|.. |.. .             |.||.         .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FIKNLIVVDPSKRFSAEKALKHPWI
.|... .|||.||...| .|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 94262.m00256.AA S_TKc 30-283 34 1.2e-99 338.24 SMART 1-231 (231) Show / Hide
Range on Protein: 30-283
Range on HMM: 1-231/231
Sequence Identity: 34% (94 aa)

FQMEQKLGAGYFAEVFQATGKKDNKEYAVKVIDRTQAANPQRIWAEVQIQLRLQHPNIIKLYKVFADKYHVALVLEFAKG--GELYEHLLDNES------
... .|.| | |..|.... ||.....|.|.|.       ..|. |.||  . .||||.||| || |  |. .|.|.. |  |.|.... .. .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

YNEIDAASIIKHLLTALVYLHKNGIVHRDIKPENILFADTAAKDPKLADFGLSGLLIEGSLLHSCAGTPIFMAPEVIKAKGYNY-SCDMWSVGIMTYLLL
..| .|..... .. || |.|..||.|||.||||||. .      |..||||. .|      ... ||| .|||||.   ||.. .||.||.|.. | .|
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

CGEVPFNGETHYDLFKKICSGEFKFIEAFDSISETAKDFIKNLIVVDPSKRFSAEKALK-------HPWI
||. ||   ... .||||.             |. |||||... ..||.|| .| .||.       |||.
CGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 94262.m00256.AA Ciliate-E2a 30-283 34 9e-96 282.38 In-house 1-275 (275) Show / Hide
Range on Protein: 30-283
Range on HMM: 1-275/275
Sequence Identity: 34% (95 aa)

FQMEQKLGAGYFAEVFQATGKKDNKEYAVKVIDRTQAANP---QRIWAEVQIQLRLQHPNIIKLYKVFADKYHVALVLEFAKGGELYEHLLDNESYNEI-
.  . |.| | |. |. |. |...|..|.|....  . .    . .  |..|  .| |||||||| |. |. .  ||.|. .|||||. .  . ...|  
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI

-DAASIIKHLL-TALVYLHKNGIVHRDIKPENILFA--DTAA---KDPKLADFGLSGLL--IEGSLLHSCAGTPIFMAPEVIKAKG------YNYSCDMW
 ....|.. ||  .| |.|...|.|||.|||||||   ..     .| |..||||.      |.  ...  ||| ..||||.. |       | ..||||
QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMW

SVGIMTYLLLCGEVPFNGETHYDLFKKICSGEFKF-IEA-FDSISETAKDFIKNLIVVDPSKRFSAEKALKHPWI
|.|.. |.||||. ||.|.|. . ....   .. | .   .  .|  .||..| . ..||.||..|. ||.||| 
SCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF

Kinase 94262.m00256.AA CDPK 30-283 36 2.6e-90 277.19 In-house 1-271 (271) Show / Hide
Range on Protein: 30-283
Range on HMM: 1-271/271
Sequence Identity: 36% (98 aa)

FQMEQKLGAGYFAEVFQATGK-KDNKEY-AVKVIDRTQAANPQ---RIWAEVQIQLRLQHPNIIKLYKVFADKYHVALVLE--FAKGGELYEHLLDNESY
.... .|| | | .|. .. | |.| |  |.|.|   .  ...   .   |. |   | ||||||.| .. |.... .|.|  . .|||| .   .. ..
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

NEIDAASIIKHLLTALVYLHKNGIVHRDIKPENILFADTAAK-----DPKLADFGLSGLLIE-----GSLLHSCAGTPIFMAPEVIKAKGYNYSCDMWSV
.|..||.|.. .| |..| |.|.|||||.|||||||           . |. |.|.|          .  .   .|||  .||||.. | ||..|| || 
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC

GIMTYLLLCGEVPFNGETHYDLFKKICSGEFKFI-EAFDSISETAKDFIKNLIVVDPSKRFSAEKALKHPWI
|.  | ||||. ||.|..  . ..|.  |...|  . .|.||. ||| |......|| ||.||. ||.|||.
GVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF

Kinase 94262.m00256.AA RAD53 30-283 33 8e-89 264.65 In-house 1-305 (305) Show / Hide
Range on Protein: 30-283
Range on HMM: 1-305/305
Sequence Identity: 33% (103 aa)

FQMEQKLGAGYFAEVFQATGKKDNKEYAVKVIDR--------TQAANPQRIWAEVQIQLRLQHPNIIKLYKVFADK-YHVALVLEFAKGGELYEHLLDNE
. |  .||.| |..|  |  ||. . .|.| ||         ...... ..  || |  .|.||.||..| .| ..   . .|||.. ||||.. . .|.
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

S----YNEIDAASIIKHLLTALVYLHKNGIVHRDIKPENILFADTAAKD----------------PKLADFGLSGLLIEGSLLHSCAGTPIFMAPEVIKA
     ..| ..  . . ...|. ||| |||.|||.||||||.....                    |..|||||  . |||..    ||| . |||||  
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

K---------------GYNYSCDMWSVGIMTYLLLCGEVPFN-GETH----YDLFKKICS-GEFKF-IEAFDSISETAKDFIKNLIVVDPSKRFSAEKAL
|               ||. ..|.|| |  .|..|||  ||  . |      .||..| . | . |  .  |.||| |||.||....||| ||.....||
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL

KHPWI
 |||.
NHPWM

Kinase 94262.m00256.AA Pkinase 30-283 32 1.6e-88 305.2 Pfam 1-293 (293) Show / Hide
Range on Protein: 30-283
Range on HMM: 1-293/293
Sequence Identity: 32% (96 aa)

FQMEQKLGAGYFAEVFQATGKKDNKEYAVKVIDRTQAANPQRIWA----EVQIQLRLQHPNIIKLYKVFADKYHVALVLEFAKGG----ELYEHLL--DN
.. ..|.|.| |..|.... |...|..|||.|..  .   ... .    |.|| .||.||||..|| .| || |. .|.|.. ||    .|....   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

ESY--NEIDAASIIKHLLTALVYLHKNGIVHRDIKPENILFADTAAKDP----KLADFGLSGL--LIEGSLLHSCAGTPIFMAPEVIK-AKGYNYSCDMW
 ..   | .. .... .| .| |.|..||.|||.||||||.      ..    |..||||. .  .  .| ... .||| .||||||. ...| ...|||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SVGIMTYLLLCGEVPFNGE------THYDLFKKICSGEFKFIEA-FDSIS-----------------ETAKDFIKNLIVVDPSKRFSAEKALKHPWI
|.|.. | .|||. || |.      ... ....| .....| .   .|||                 |..|||||... .||.|| .|| .|.|||.
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 94262.m00256.AA Ciliate-E2 30-283 24 1.7e-88 300.32 In-house 1-365 (365) Show / Hide
Range on Protein: 30-283
Range on HMM: 1-365/365
Sequence Identity: 24% (92 aa)

FQMEQKLGAGYFAEVFQATGKKDNKEYAVKVIDRTQ---------AA-----------NPQRIWAEVQIQL-----------------RLQHPNIIKLYK
.   .|.| | |. |.... .|..|..| |.|| .          ..           |  ...  .. ..                 .|.||||||.| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VFA--DKYHVALVLEFAKGGELYEHLLDN-----------ESYNEIDAASIIKHLLT---------------ALVYLHKNG-IVHRDIKPENILFADTAA
.|   |. .. ||.|...||.|.... .|           ....|  .. |.|..|                || |||... |.|||||||||||     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

KDPKLADFGLS----------------GLLIEGS-----------------LLHSCAGTPIFMAPEVIKAKG---------YNYSCDMWSVGIMTYLLLC
  .|..|||||                ..... .                 . ....||| .||||... |.         |.|.||.||.|.. | .|.
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GEVPFNGETHYDLFKKICSGEFKFIEA---------------FDSISETAKDFIKN----LIVVDPSKRFS-AEKALKHPWI
|. ||        ...|. ....| ..               ....|. .||.||.    ....||.||.. .|..|.|||.
GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 94262.m00256.AA DCAMKL 30-283 35 9.5e-87 269.85 In-house 1-279 (279) Show / Hide
Range on Protein: 30-283
Range on HMM: 1-279/279
Sequence Identity: 35% (99 aa)

FQMEQKLGAGYFAEVFQATGKKDN-KEYAVKV-----------------IDRTQAAN-PQRIWAEVQIQLRLQHPNIIKLYKVFADKYHVALVLEFAKGG
.|   . | | || |. .. .... ..|| |.                 ||. .  .    | .||.|  ...||.||.|| ..  . |  ||.|...||
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQGG

ELYEHLLDNESYNEIDAASIIKHLLTALVYLHKNGIVHRDIKPENILFAD--TAAKDPKLADFGLSGLLIE-GSLLHSCAGTPIFMAPEVIKAKGYNYSC
 |....  |  . | ||| .. .|  ||.|||  .|||||||||| |  .     |  ||.||||     .   .|    |||   |||... .||   .
DLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCKV

DMWSVGIMTYLLLCGEVPFNGE--THYDLFKKICSGEFKFIE-AFDSISETAKDFIKNLIVVDPSKRFSAEKALKHPWI
|.|..|. .| ||||  || ..     .||..| .|.| |     | ||  ||| |... .||| ||..||  ..|||.
DIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV

Kinase 94262.m00256.AA CAMKL 30-283 28 4e-85 271.58 In-house 1-297 (297) Show / Hide
Range on Protein: 30-283
Range on HMM: 1-297/297
Sequence Identity: 28% (86 aa)

FQMEQKLGAGYFAEVFQATG-KKDNKEYAVKVIDRTQAANPQRIWA---------------EVQIQLRLQ---HPNIIKLYKVFADKYH------VALVL
..... || | |..|  ||  .  ....|.|.||.  . | . ...               |.||. .|.   |||||||| |. .. |      . ||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFAKGGE--LYEHLLDN----ESYNEIDAASIIKHLLTALVYLHKNGIVHRDIKPENILFADTAAKDPKLADFGLSGLLIE-----GSLLHSCAGTPIFM
| . |||  |....  .    ..  | .|  . . .. |. |.|..|||||||||||||. .      |..|||.| . ..     | .|. . |.| .|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVIKA--KGYN-YSCDMWSVGIMTYLLLCGEVPFNGET-------HYDLFKKICSGEFKFIEAFDSISETAKDFIKNLIVVDPSKRFSAEKALKHPWI
|||...   | |. .  |.|| |.. | ..||..||...|       .. .....  .  ...  . ..|  ..|.|. . .|.|.||....  ..||| 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM





Kinase 94262.m00256.AA CAMK-Unique 30-283 25 1.7e-82 272.14 In-house 1-363 (363) Show / Hide
Range on Protein: 30-283
Range on HMM: 1-363/363
Sequence Identity: 25% (94 aa)

FQMEQKLGAGYFAEVFQATGKKDNKEYAVKVIDRTQAANPQRIW--------------------AEVQIQLRLQHPNIIKLYKV----FADKY-------
  | . .| | | .|. .. ..  |..|.|..    . |  ..                      |.|| ... |||||||| .    | |.        
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------HVALVLEFAKGGELYEHLLD--------------------NESYNE--IDAASIIKHLLTALVYLHKNGIVHRDIKPENILFADT-------
        .  .|.|.. ||.|.. ...                    . ...|   |...|.  || |. |.|...|||||.|.|||..          
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-------AAKDPKLADFGLSGLLI-EGSL--LHSCAGTPIFMAP--------------EVIKAKGYNYSC----DMWSVGIMTYLLLCGEVPFNGETHY-
        ... ||.||||. ..    .   ...  |||..|||              |||.. .| . |    | || | ..|..|||. ||..|.   
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------DLFKKICSGEF-KF-IEAFDS---ISETAKDFIKNLIVVDPSKRFSAEKALKHPWI
        .|..||.|.. .|  .....   ||. ||||.|.. .|||..| ||. .|.|.||
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI

Kinase 94262.m00256.AA RSK 32-283 29 2.4e-81 276.58 In-house 1-278 (278) Show / Hide
Range on Protein: 32-283
Range on HMM: 1-278/278
Sequence Identity: 29% (83 aa)

MEQK--LGAGYFAEVFQATGKKDNKEYAVKVIDRTQAANPQR----IWAEVQIQLRLQ-HPNIIKLYKVFADKYHVALVLEFAKGGELYEHLLDNES---
....  .| | .  .   |... ...||.||...  ... |.     ..|..| .| | ||.|..|. .| .. .. |..|. .||||..||.  ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

YNEIDAASIIKHLLTALVYLHKNGIVHRDIKPENILFADTA-AKDPKLADFGLSGL-LIE-GSLLHSCAGTPIFMAPEVIK----AKGYNYSCDMWSVGI
  | .|. ..  .  |. .||. ||.|||.||||||..|       || |||.. .  .. ......  .|  .||||..|     .|.. .|| || |.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

MTYLLLCGEVPFNG---ETHYDLFKKICSGEFKF-IEAFDSISETAKDFIKNLIVVDPSKRFS-----AEKALKHPWI
  | .| | .|| |   ... ...|.|..|.| . ... ...|..|||.|. .  .||.|| .     ||  ..|||.
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase 94262.m00256.AA TyrKc 30-283 22 2.7e-14 8.54 SMART 1-280 (280) Show / Hide
Range on Protein: 30-283
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

FQMEQKLGAGYFAEVFQATGKKDNKEYAVKVIDRTQAANPQRIWAEVQIQLRL--QHPNIIKLYKVFADK-------YHVALVLEFAKGGELYEHLLDNE
 ....||| | | ||...| |    . |||..        . .  | .|  .|  .||||..|| |  ..         . .|.|....| | ..| ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

S-YNEIDAASIIKHLLTALVYLHKNGIVHRDIKPENILFADTAAKDPKLADFGLSGLLIEG-------SLLHS----CAG--TPIF-MAPEVIKAKGYNY
   .  |  |.         |||.....|||.   |.| ..      | .|||||  . ..       .  ..    ..    ||  ||||.|. . .. 
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

SCDMWSVGIMTY-LLLCGEVPFNG-----ETHYDLFKKICSGEFKFIEAFD-------SISETAKDFIKNLIVVDPSKRFSAEKALKHPWI
  | || |.. . ..  |. |  |      . ....... .|.   . . |         .|  .  .|     ||..| . .    |  .
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF

Kinase 94262.m00256.AA Pkinase_Tyr 30-151 24 4.2e-13 45.01 Pfam 1-137 (270) Show / Hide
Range on Protein: 30-151
Range on HMM: 1-137/270
Sequence Identity: 24% (33 aa)

FQMEQKLGAGYFAEVFQATGK----KDNKEYAVKVI-DRTQAAN--PQRIWAEVQIQLRL-QHPNIIKLYKVFA-DKYH--VALVLEFAKGGELYEHLLD
 .. .|||.| | ||...| |    ... . |||.. . .   .   .   .|..|   | .||||..|| |   .. .  . .|.|....| |...| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----NESYNEIDAASIIKHLLTALVYLHKNGIVHRDI
    ... .  |  ..      .. ||. ....|||.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL

Kinase 94262.m00256.AA Pkinase_Tyr 167-242 26 0.2262 5.27 Pfam 151-233 (270) Show / Hide
Range on Protein: 167-242
Range on HMM: 151-233/270
Sequence Identity: 26% (22 aa)

KLADFGLSGLL----IEGSLLHSCAGTPIF-MAPEVIKAKGYNYSCDMWSVGIMTYLLLC-GEVP-FNGETHYDLFKKI-CSGE
| .||||. ..       .  .. .  ||. ||||.|. . ..   | || |.  . ..  || | . | . ......|  .|.
KICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGY