Gene 91962.m00094 (T.vaginalis)

91962.m00094

Species: T.vaginalis
Alias: TvagK0736, 91962.m00094
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: YSK

Sequence

Name Sequence Type Origin Length Description Download
91962.m00094.AA Protein None 385 None Fasta, JSON
91962.m00094.kin_dom Protein Kinase Domain None 250 None Fasta, JSON

Protein domain

Protein domains of 91962.m00094.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 91962.m00094.AA YSK 13-262 55 8.99999999999e-159 481.95 In-house 1-257 (257) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-257/257
Sequence Identity: 55% (142 aa)

FQQCEIIGRGSFGIVFKAIYKKTGQTVAIKEIDLEKTSDELTEIQREIDMLRVCKSEYVVSCEGSTLVDSKLWIVMEYMGGGSIRDLIQI---RKMPENT
|   | ||||||| |.|.| ..|...|||| ||||. .||   ||.||  |  |.| |.    ||.| |.||||.||| ||||..||.      ...|  
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

IAIVLKQILLALNFLHKGRKIHRDIKAANILLSNDGDIKLADFGVASSLE-ARTKAYTFVGTPFWMAPEIIAE--EGYNEKCDIWSLGITAIEVATGMPP
|||.|. ||..| .||. |||||||||||.|||..||.||.|||||. .    .|  ||||||.|||||.| .   .|..| |||||||||.| |.| ||
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPP

YHELYPQRVLMLIPQNPPPTLQG-DFSPQFKDFVSKCLVKDPTKRPSAAELLTHPFI
| .. | ||. ||| |.||.|.| ..|  ||.||  ||.||| .|||| ||| | ||
YCDYHPMRVMFLIPKNNPPKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase 91962.m00094.AA STE20 13-262 48 4.4e-142 478.33 In-house 1-288 (288) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-288/288
Sequence Identity: 48% (139 aa)

FQQCEIIGRGSFGIVFKAIYKKTGQT----VAIKEIDLEKTS---DELTEIQREIDMLRVCKSEYVVSCEGSTLVD----SKLWIVMEYMGGGSIRDLIQ
..  | ||.||.| |.||. |.||.     |||| ..||| .   ||. .|| ||.... ||....|.  || |.|    ..|||||||.||||..|...
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---IRK-------MPENTIAIVLKQILLALNFLHKGRKIHRDIKAANILLSNDGDIKLADFGVASSLEA-----RT-KAYTFVGTPFWMAPEIIAE----
   ...       | |  || .....| .|..||. ..|||||||.||||. ||..|||||||...|.      .  |  ||||||.|||||.|..    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-EGYNEKCDIWSLGITAIEVATGMPPYHELYPQRVLMLIP--QNPPPTLQG----DFSPQFKDFVSKCLVKDPTKRPSAAELLTHPFI
  ||..||||||||||||| |.| |||... | |....||  |||||||..     .||.|.|||.|||.||| |||.| .||.||||
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase 91962.m00094.AA STE 13-262 34 3.6e-129 435.43 In-house 1-359 (359) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-359/359
Sequence Identity: 34% (127 aa)

FQQCEIIGRGSFGIVFKAIYKK---------------TGQTVAIKEIDLEKTS----------------DELTEIQREIDMLRVCK--SEYVVSCEGSTL
..  |.||.|.|| |.||...|               ||. .|||...||. .                .|. .|..||.... |.  ....| . |. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VD-------SKLWIVMEYMGGGSIRDLIQ---IRKMP------------ENTIAIVLKQILLA-LNFLHKGRKIHRDIKAANILLSNDGDIKLADFGVAS
..       ..|||.||||.|||..|.|.   ....|            |. ||....||| . |..||. ..||||||.|||||     .||.||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

SLEA-----------------RTKAYTFVGTPFWMAPEIIAE------EGYNEKCDIWSLGITAIEVATGMPPYHELYPQRVLMLIPQN-----------
.|.                    | .|||||| |||||.|         ||..||||||||.|.|| ||| ||.|...| |....||.|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----PPPTLQG-------------------DFSPQFKDFVSKCLVKDPTKRPSAAELLT--HPFI
    |||.|.                     .|| ||||..|||.||| |||.| .||   ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 91962.m00094.AA MST 13-262 49 9.3e-128 408.2 In-house 1-254 (254) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-254/254
Sequence Identity: 49% (128 aa)

FQQCEIIGRGSFGIVFKAIYKKTGQTVAIKEIDLEKTSDELTEIQREIDMLRVCKSEYVVSCEGSTL--VDSKLWIVMEYMGGGSIRDLIQIRKMP--EN
|   |..|.||.| |.|||.|.||. |||| .  .  .| | ||  || ..  |||.|.|   || .   .. .|||||| |.||. |.. |.. .  | 
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVN--ED-LQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQ

TIAIVLKQILLALNFLHKGRKIHRDIKAANILLSNDGDIKLADFGVASSLEA-RTKAYTFVGTPFWMAPEIIAEEGYNEKCDIWSLGITAIEVATGMPPY
 || .|.. |. |  ||. .||||||||.||||...|  |||||||.. |     |. |..|||.||||| | | .|. | ||||||||||| | |||||
QIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPY

HELYPQRVLMLIPQNPPPTLQ--GDFSPQFKDFVSKCLVKDPTKRPSAAELLTHPFI
... | |.. .|||.||||..    .|..| |||.|||.|.| .|..| .|| ||||
SDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase 91962.m00094.AA PAKL 13-262 47 8.10000000001e-108 364.5 In-house 1-256 (256) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-256/256
Sequence Identity: 47% (122 aa)

FQQCEIIGRGSFGIVFKAIYKKTGQTVAIKEIDLEKTSDELTEIQREIDMLRVCKSEYVVSCEGSTLVD-SKLWIVMEYMGGGSIRDLIQIRK--MPENT
|   |  | ||.| |.||| | |. . |||.| . | | |  .|. ||..|  ||. ..||  ||     ...|| |.|   |||.|....    . |  
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEI-KESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQ

IAIVLKQILLALNFLHKGRKIHRDIKAANILLSNDGDIKLADFGVASSLEARTK--AYTFVGTPFWMAPEIIAEEGYNEKCDIWSLGITAIEVATGMPPY
|...|.| |. |  ||    ||||||||||||. |...|.||||| . |.      |   .|||.|||||||    || ||||||||||||| | | || 
ISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADGFPPH

HELYPQRVLMLIPQNPPPTLQG--DFSPQFKDFVSKCLVKDPTKRPSAAELLTHPFI
 .. | | .. ||  ||||.    ..|| | ||. .|.|||| ||.|. .||.||||
YDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase 91962.m00094.AA S_TKc 13-262 35 3.7e-101 343.28 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-231/231
Sequence Identity: 35% (95 aa)

FQQCEIIGRGSFGIVFKAIYKKTGQTVAIKEIDLEKTSDELTEIQREIDMLRVCKSEYVVSCEGSTLVDSKLWIVMEYMGG--GSIRDLIQIRK------
..  ..||.|.|| |.|.. ||||. ||||.|.          |.|||..|.  . ...| . ..    ..|..||||..|  |. .|.|. |.      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-MPENTIAIVLKQILLALNFLHKGRKIHRDIKAANILLSNDGDIKLADFGVASSLEARTKAYTFVGTPFWMAPEIIAEEGYNE-KCDIWSLGITAIEVAT
 .|| ... ...||..||...|. . ||||.| .||||..   ||..|||.|  |      .||.|||..||||..   ||.  |||.||.|.. .| ..
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GMPPYHELYPQRVLMLIPQNPPPTLQGDFSPQFKDFVSKCLVKDPTKRPSAAELLT-------HPFI
| ||..    . ... .            ||..|||..|||.|||.|||.| |.|.       ||..
GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 91962.m00094.AA FRAY 13-262 41 6e-100 311.15 In-house 1-277 (277) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-277/277
Sequence Identity: 41% (116 aa)

FQQCEIIGRGSFGIVFKAIYKKTGQTVAIKEIDLEKTS-DELTEIQREIDMLRVCKSEYVVSCEGSTLVDSKLWIVMEYMGGGSIRDLI--QIRKMP---
..  | || |  ..|.||. .     .||| |.|||     . |. .||     |. . ||.   | .|   ||.|| | ..||. |..   ...     
YELQEVIGEGATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNEELWLVMRYLECGSCLDIMKFKMPQGEPHK

-----ENTIAIVLKQILLALNFLHKGRKIHRDIKAANILLSNDGDIKLADFGVASSLEA-----RTKA-YTFVGTPFWMAPEIIAEEG-YNEKCDIWSLG
     | .|| .|| .| .| ..||  .||||||| |||.  || | .||||| . |.      | .   |||||| |||||.. . . |. | ||||.|
QGVFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLATGGDLSRCCVRHTFVGTPCWMAPEVMEQVHGYDFKADIWSFG

ITAIEVATGMPPYHELYPQRVLMLIPQNPPPTLQGD---------FSPQFKDFVSKCLVKDPTKRPSAAELLTHPFI
||||| ||| .|||.. |  ||||. ||.||.|..|         ... ||. ..||| ||| ||| |.||| | | 
ITAIELATGKAPYHKYPPMKVLMLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF
Kinase 91962.m00094.AA PAKA 13-262 43 1.1e-95 324.16 In-house 1-260 (260) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-260/260
Sequence Identity: 43% (114 aa)

FQQCEIIGRGSFGIVFKAIYKKTGQT--VAIKEIDLEKTSDELTEIQREIDMLRVCKSEYVVSCEGSTLVDSKLWIVMEYMGGGSIRDLIQIRK------
..  | || |. | |..|. .||.|.  |||| ... |. .    |  || ... || . .|    | |||..||.|||||.||.  |.|.         
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNM-KNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNY

MPENTIAIVLKQILLALNFLHKGRKIHRDIKAANILLSNDGDIKLADFGVASSLEA-RTKAYTFVGTPFWMAPEIIAEEGYNEKCDIWSLGITAIEVATG
|.|. || |....| .|.|.|.   ||||||  ||||  ||..|..||| .  |.  . |  | |||| |||||.|    |.|| ||||||| ||| . |
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEG

MPPYHELYPQRVLMLIPQN--PPPTLQGDFSPQFKDFVSKCLVKDPTKRPSAAELLTHPFI
 ||| .  | | . || .|  |.   .  .|..|.||..||| .|. .|.|| |||.|||.
EPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase 91962.m00094.AA Pkinase 13-262 29 1.2e-87 302.3 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

FQQCEIIGRGSFGIVFKAIYKKTGQTVAIKEIDLEKTSDELTEIQR---EIDMLRVCKSEYVVSCEGSTLVDSKLWIVMEYMGGG----SIRDLIQ---I
..  ..||.|||| |.|.. |.||..||.|.|........  .. |   || ... ......| . ..   ......||||..||    .  |.|.    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RKM--PENTIAIVLKQILLALNFLHKGRKIHRDIKAANILLSNDGDI----KLADFGVASS--LEARTKAYTFVGTPFWMAPEIIA-EEGYNEKCDIWSL
...  .|...  ...||| .|...|. . ||||.| .|||..|.|.|    |..|||.|    .   . ..||.|||..||||.|   ..|  |.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GITAIEVATGMPPYHEL----YPQRVLMLIPQNPPPTLQGDFS-----------------------PQFKDFVSKCLVKDPTKRPSAAELLTHPFI
|.. .|...| ||. .        . . .| .. .| |  |..                       . .|||...|| |||.|||.|...| ||..
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 91962.m00094.AA KHS 13-262 44 6.2e-86 289.02 In-house 1-258 (258) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-258/258
Sequence Identity: 44% (114 aa)

FQQCEIIGRGSFGIVFKAIYKKTGQTVAIKEIDLEKTSDELTEIQREIDMLRVCKSEYVVSCEGSTLVDSKLWIVMEYMGGGSIRDLIQIR-KMPENTIA
..    .| | .| |.||  ..... .|.| | .|  .|... ||.|| |.. |.   .|.  || |   ||||.||| ||||. |. ..  .. |  ||
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKME-PGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGPLSELQIA

IVLKQILLALNFLHKGRKIHRDIKAANILLSNDGDIKLADFGVASSLEAR-TKAYTFVGTPFWMAPEIIAEE---GYNEKCDIWSLGITAIEVATGMPPY
 | ...| .|..||   |.||||| |||||...||.|||||||.. . |   |   |.|||.|||||. | |   |||. ||||..||||||.|   || 
YVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPPM

HELYPQRVLMLIPQNP--PPTLQ--GDFSPQFKDFVSKCLVKDPTKRPSAAELLTHPFI
 .| | |.|.|. .    ||.|.    .|..| .||  .|.|.| |||.|  ||.|||.
FDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase 91962.m00094.AA STE11 13-262 35 7.6e-83 281.53 In-house 1-303 (303) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-303/303
Sequence Identity: 35% (109 aa)

FQQCEIIGRGSFGIVFKAIYKKTGQTVAIKEIDLEKTS-------DELTE------IQREIDMLRVCKSEYVVSCEGSTLV---DSKLWIVMEYMGGGSI
.| .||||.|.|| |.|.. ..||. .|.|.| .....       .|. .      || || ...  . .  |   |..|    .... | |||. |||.
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

RDLIQIR----KMPENTIAIVLKQILLALNFLHKGRKIHRDIKAANILLSNDGD-IKLADFGVASSLE-ARTKAYT----------FVGTPF--------
..... .    |..|..| .  |||| .|..||. . ||||||.|||||  ||  .|||||| | .|.   |.. .          . |||.        
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

WMAPEIIAEEG---YNEKCDIWSLGITAIEVATGMPPYHELY--PQRVLMLIP-Q-NPPPTLQGDFS------PQFKDFVSKCLVKDPTKRPSAAELLTH
|||||.| .||   |  |.|||||| | || ||| ||.|..   ..  .. |  . .|.| .  ..|      .. .||...|...|| |||.|..|| |
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQH

PFI
|||
PFI
Kinase 91962.m00094.AA STE7 13-262 34 2e-82 280.12 In-house 1-288 (288) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-288/288
Sequence Identity: 34% (101 aa)

FQQCEIIGRGSFGIVFKAIYKKTGQTVAIKEIDLEKTS-DELTEIQREIDMLRVCK-SEYVVSCEGSTLVDSK--LWIVMEYMGGGSIR---DLI-----
... . .|.|..|.| |. .|..|.  |.|.| |. ..  | . | .|.| |. |. ..|.| . |    . .   ||.||||.||...   ...     
LEHIGELGHGNYGVVYKMRHKPSGKIMAVKRIRLTNNDPEEQKQILMELDVLHKCNDCPYIVQFYGAFYTEGDDCIWICMEYMDGGCLDKFYKRVKKVYR

--QIRKMPENTIAIVLKQILLALNFLHKGRK-IHRDIKAANILLSNDGDIKLADFGVASSLEART-KAYTFVGTPFWMAPEIIAE--EGYNEKCDIWSLG
  . ...||. ....  ... .|..||. .| ||||.|  |||.  .|..||.|||..  |.    .| ||||... |||| |    ..|  ..|.||||
GIKKGRIPEQILGKIAVAVIKGLHYLHEKHKIIHRDVKPSNILVNSRGQVKLCDFGICGQLVDSMDAATTFVGCQPYMAPERIDGNKQHYDVRSDVWSLG

ITA-IEVATGMPPY------------HELYPQ------RVLMLIPQN-PPPTLQGDFSPQFKDFVSKCLVKDPTKRPSAAELLT-HPFI
||  ||.|||  ||            ... .|       .|. | .  |||.|   ||| |.|||.||| |||..||.  .|.  ||||
ITMGIEMATGRYPYPNWNTHPPDQKQYNNMFQPEMAIFEQLTCIVNENPPPRLP-KFSPEFQDFVNKCLQKDPNERPKYHQLMKEHPFI
Kinase 91962.m00094.AA Pkinase_Tyr 13-216 25 1.7e-36 124.19 Pfam 1-225 (270) Show / Hide 
Range on Protein: 13-216
Range on HMM: 1-225/270
Sequence Identity: 25% (58 aa)

FQQCEIIGRGSFGIVFKAIYK----KTGQTVAIKEIDLEKTSDE---LTEIQREIDMLRVC-KSEYVVSCEGSTL-VDSK--LWIVMEYMGGGSIRDLIQ
 .  . .|.|.|| |.|...|    .|...||.| .  |....|   . .  ||. ...   . . .|.. |  .  .    ..|||||| .|. .|  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

IR-----KMPENTIAIVLKQILLALNFLHKGRKIHRDIKAANILLSNDGDIKLADFGVASSLEARTKAYT-FVGT-----PFWMAPEIIAEEGYNEKCDI
 .     . .  ..     ||  ....|.  . ||||. | |.|..... .| .||| |  .    . |   ...      .||||| |..  ...| |.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI--YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV

WSLGITAIEVAT-GMPP-YHELYPQRVL
|| |..  |. | |. | | .. ...|.
WSFGVLMWEIFTYGEQPTYPGMSNEEVY
Kinase 91962.m00094.AA TyrKc 13-262 23 8.2e-32 112.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

FQQCEIIGRGSFGIVFKAIYKKTGQTVAIKEIDLEKTSDELTEIQREIDMLRVC--KSEYVVSCEGSTLVD-------SKLWIVMEYMGGGSIRDLIQIR
 .  ...|.| ||.|.|...|   ..||.| .  ..    . .. ||. ...    . . .| . |  . .         |.|||||| .|. .| .. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

K--MPENTIAIVLKQILLALNFLHKGRKIHRDIKAANILLSNDGDIKLADFGVASSLEAR-----TKAYTFV----GTP-----FWMAPEIIAEEGYNEK
.   .  .      ||    ..||. . ||||. | |.|..... .| .||| .  ..        | |  .    |.       ||||| | .  ...|
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

CDIWSLGITAIEVAT-GMPPYHE-----LYPQRVLMLIPQN----PPPTLQGD-----FSPQFKDFVSKCLVKDPTKRPSAAELLTHPFI
 |.|| |..  |. | |..|| .     . .|.|. .. |     .||           ..   .  ..|   || .||. .|.  | ..
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF