Gene 85337.m00291 (T.vaginalis)
85337.m00291
Species: T.vaginalis
Alias: TvagK0288, 85337.m00291
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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85337.m00291.AA | Protein | None | 796 | None | Fasta, JSON |
85337.m00291.kin_dom | Protein Kinase Domain | None | 251 | None | Fasta, JSON |
Protein domains of 85337.m00291.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 85337.m00291.AA | TKL | 28-273 | 27 | 1.4e-81 | 277.37 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 28-273 Range on HMM: 1-364/364 Sequence Identity: 27% (102 aa) IGGGSFGDVYLAKYIP--------TGQMTAVKELKHETLEEP-------------------------FLQYFLREIRILAKCDNYFLLHFTGYTATHP-- || |.|| || .|. ||. ||| .| . | | . . .||... ... ...| || | IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG ------------FLIVTEYIQNGSLFDSLHDQTKSLDGTQKTIIALGIACGMARLHSFN--------IMHRDLKSLNILLDES--------------YFP . ||.||...|||.. || |. .||.||.||. ||| | | |||||| |||.|| ... CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC RICDFGASRIKSAESE-------------------LVTQNIGTVHWMAPEMFDST----------------NYTLAVDVYAYAILLWELLAEEIPYNGYS ||||| || .| ... .|| |||||... . |. ..|||...|.|||.|. ..|| .| KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP VP---------QIMRTVCMNDQRLTIP------------QGTPPNLAKLIQLCWNRDPEKRPPFDRIFKIF . ... || . .|..|| .|| ..||.| ||. |||||| |..| |.. YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | 85337.m00291.AA | MLK | 22-273 | 32 | 5e-68 | 232.31 | In-house | 1-291 (291) | Show / Hide |
Range on Protein: 22-273 Range on HMM: 1-291/291 Sequence Identity: 32% (94 aa) FQYEKKIGGGSFGDVYLAKYIPTG---QMTAVKELKHETLEEPFLQY-----FLREIRILAKCDNYF----LLHFTGYTATH-P-FLIVTEYIQNGSLFD .| ...|| ||||.|..... . |||. .... . | | .|.|.|.. . | | . . . |.||.||...|||.. IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN SLHDQTK-------------SLDGTQKTIIALGIACGMARLHSFN---IMHRDLKSLNILLDE------SYFPRICDFGASRIKSAESELVTQNIGTVHW ||.... | .. .|| .| ||. ||| | |||||| |||.|| .|||||.|| .. . . |.||. | VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW MAPEMF---DSTNYTLAVDVYAYAILLWELLAEEIPYN-GYSVPQIMRTVCMNDQRLTIPQGTPPNLAKLIQLCWNRDPEKRPPFDRIFKIF ||||.. .. |. ..||. ....|||.|. |.|| .|. .| | .| .|..||.. |. ..||.. ||| ||.||| |. | ... MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL |
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Kinase | 85337.m00291.AA | TKL-Unique | 26-273 | 31 | 1.3e-65 | 224.26 | In-house | 3-290 (290) | Show / Hide |
Range on Protein: 26-273 Range on HMM: 3-290/290 Sequence Identity: 31% (92 aa) KKIGGGSFGDVYLAKYIPTGQMTAVKELK-HETLEEPFLQYFLREIRILAKCD-NYFLLHFTGYTA----THP-FLIVTEYIQNGSLFDSLH-------- .|||.|..| || .|. | .|.| .. | .. ..| | .|.... | . ...|. ||.. . | . ||.||.. ||| | || NKIGEGGYGQVYKGKW--RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN -DQTKSLDGTQKTIIALGIACGMARLHSFN--IMHRDLKSLNILLDES-----YFPRICDFGASRIKSAESELVTQNI---------GTVHWMAPEMFDS . . |. |. .|. || || .||. . |.||||||.|.|.|. . .||||| |...| ... . .. |. |||||.. . NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM --TNYTLAVDVYAYAILLWELLAEEI------PYNGYSVPQIMRTVCM--NDQRLTIPQGTPPNLAKLIQLCWNRDPEKRPPFDRIFKIF . |. .|||...| |||.. .| || |.. |. .| .|..||. |... .||| ||..||..|| || | . NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL |
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Kinase | 85337.m00291.AA | Dicty4 | 22-275 | 35 | 3.5e-64 | 212.98 | In-house | 1-277 (277) | Show / Hide |
Range on Protein: 22-275 Range on HMM: 1-277/277 Sequence Identity: 35% (98 aa) FQYEKKIGGGSFGDVYLAKYIPTGQMTAVKEL--KHETLEEPFLQYFLREIRILAKCDNYFLLHFTGYTAT---HP--FLIVTEYIQNGSLFDSLHD--- . |..||.|||| ||... |. ||| | . ....| .|. |..|. |..| . .. | |. || ..||||| |.|. ||| INIEQRIGKGSFGEVYKGTW--RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS ---QTKSLD-GTQKT--IIALGIACGMARLHS--FNIMHRDLKSLNILLDESYFPRICDFGASR----IKSAESELVTQNIGTVHWMAPEMFDSTNYTLA | ..|| .. | .|. .| ||. ||. .| |||||| |.| |... .|||| |. ... . |. .||. |||||. . |. . EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTA-CGTPCWMAPEVMMHQPYNEK VDVYAYAILLWELLAEEIPYN--GYSVPQIMRTVCMNDQRLTIPQGTPPNLAKLIQLCWNRDPEKRPPFDRIFKI--FKS .||| ..|.|||.| ..||. . . .|. | || |. ||. .||....||| ||. ||..|| | | .. . ADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH |
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Kinase | 85337.m00291.AA | HH498 | 22-273 | 31 | 1.3e-58 | 184.32 | In-house | 1-284 (284) | Show / Hide |
Range on Protein: 22-273 Range on HMM: 1-284/284 Sequence Identity: 31% (92 aa) FQYEKKIGGGSFGDVYLAKYIPTGQMTAVKELKHETLEEPFL------QYFLREIRILAKCDNYFLLHFTGYTATHP--FLIVTEYIQNGSLFDSL---- . . .||| ||||.||. .. . . ||| . .. . | ||. |. . .. | . . | |.|||.|..||||| | IEFHEKIGSGSFGKVYKGEW--RNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIP ----------HDQT---KSLDGTQKTIIALGIACGMARLHS---FNIMHRDLKSLNILLDESYFPRICDFGASR-IKSAESELVTQNIGTVHWMAPEMFD | | .| | .|.. .| || ||. | |||| | |||..| . ||| || ... . . | .| ||||| | IGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFS -STNYTLAVDVYAYAILLWELLAEEIPYNGYSVPQIMRTVCM-NDQ-RLTIPQG----TPPNLAKLIQLCWNRDPEKRPPFDRIFKIF .. |. |||. ||. .||.. |.|. | .. | . . | .||| | ||| ||. || || || | | QCQKYSIKVDVFSYAMCIWEMHTREVPFHHYK--PAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL |
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Kinase | 85337.m00291.AA | Pkinase_Tyr | 22-273 | 29 | 5e-54 | 183.59 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 22-273 Range on HMM: 1-270/270 Sequence Identity: 29% (79 aa) FQYEKKIGGGSFGDVYLAKYI----PTGQMTAVKELKHETLEEP-FLQYFLREIRILAKC-DNYFLLHFTGYTA--THP--FLIVTEYIQNGSLFDSLHD . ||.| |.||.||.... |.. ||| ||. . .| ... |.||..|. . .. .. . | | .||.|| ..|.| | |.. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK Q---TKSLDGTQKTIIALGIACGMARLHSFNIMHRDLKSLNILLDESYFPRICDFGASRIKSAESEL-VTQN--IGTVHWMAPE-MFDSTNYTLAVDVYA . ..|. .. ... ||.||. |.| |. |||| |.|..|. . .||||| .| ... ... . ||||| .... .| . ||.. HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVWS YAILLWELLA-EEIP-YNGYSVPQIMRTVCMNDQRLTIPQGTPPNLAKLIQLCWNRDPEKRPPFDRIFKIF . .|.||.. |.| | | | .... . . .|. .|...|. . .|...||. |||.|| | | .. FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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Kinase | 85337.m00291.AA | S_TKc | 22-279 | 26 | 1.7e-53 | 184.93 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 22-279 Range on HMM: 1-231/231 Sequence Identity: 26% (72 aa) FQYEKKIGGGSFGDVYLAKYIPTGQMTAVKELKHETLEEPFLQYFLREIRILAKCDNYFLLHFTGYTATHPFLIVTEYIQN--GSLFDSLHDQTKS---- .. .||| |.|| ||... . ||. |.|..| . ..|||.|| | . .. .. .. .. . .|.||. . |.||| .... . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF -LDGTQKTIIALGIACGMARLHSFNIMHRDLKSLNILLDESYFPRICDFGASRIKSAESELVTQNIGTVHWMAPEMFDSTNYTL-AVDVYAYAILLWELL .. . .. |.|... .|| .|.||||| |||||| ||||| .|. | .|| ..||||.. |. ..|... ..|.|.| PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML AEEIPYNGYSVPQIMRTVCMNDQRLTIPQGTPPNLAKLIQLCWNRDPEKRPPFDRIFK---IFKSHKVS . . |. . .... .. .| . .|. |...|||||| ... |.| CGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 85337.m00291.AA | Dicty5 | 95-277 | 40 | 1.4e-52 | 179.28 | In-house | 76-260 (260) | Show / Hide |
Range on Protein: 95-277 Range on HMM: 76-260/260 Sequence Identity: 40% (76 aa) IVTEYIQNGSLFDSLHDQTK----SLDGTQKTIIALGIACGMARLHSFNIMHRDLKSLNILLDESYFPRICDFGASR-IKSAESELVTQNIGTVHWMAPE .||||..|||||. | || | . |. .|..|| .| ||| || ||||||.|.|. | . | ||| || . . | ..|| |||.| HVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYH--MTMHVGTQCWMACE MFDSTNYTLAVDVYAYAILLWELLAEEIPYNGYSVPQIMRTVCMNDQRLTIPQGTPPNLAKLIQLCWNRDPEKRPPFDRIFKIFKSHK .| . |. .|||...| |||... || | | | | ||| | ..|| || | .|| | | |.|.| LFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIPVMV-MKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII |
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Kinase | 85337.m00291.AA | TyrKc | 22-273 | 26 | 9.6e-52 | 179.14 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 22-273 Range on HMM: 1-280/280 Sequence Identity: 26% (76 aa) FQYEKKIGGGSFGDVYLAKYIPTGQMTAVKELKHETLEEPFLQYFLREIRILAKC--DNYFLLHFTGYTAT--------HPFLIVTEYIQNGSLFDSLHD . .||.| | || ||..... .. ||| ||... .. |.||.||. | .. .. . |. . .| .||.|| .|.| | |.. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK QTKSLDGTQKTIIALGIACGMARLHSFNIMHRDLKSLNILLDESYFPRICDFGASRIKSAE------SELVT-----QNI--GTVHWMAPEMFDSTNYTL . | .. ... |||||. ||| |. |||| |.|..| . .|.||| || . .. . . . ||||| .. .| HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT AVDVYAYAILLWELLAEEIPYNGY-----SVPQIMRTVCMNDQRLTIPQG--------TPPNLAKLIQLCWNRDPEKRPPFDRIFKIF . ||... ...||.. . .| .. .. |. .|. |. . .... ||..|||.|| | | ..| KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | 85337.m00291.AA | TK | 22-273 | 16 | 1e-51 | 171.23 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 22-273 Range on HMM: 1-486/486 Sequence Identity: 16% (80 aa) FQYEKKIGGGSFG---DVYLAKYIPTG-------------------------QMTAVKELK--HETLEEPFLQ----------YFLREIRILAKCD---- ...||.| | || .||...... . . .||| || ... .| |.. ||.| ..... . ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG -NYFLLHFTGYTATH-------------PFLIVTEYIQNGS----LFDSLHDQTKS-------------------------------------------- .... |. . |..||.|| ..|. | | |.. . HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY -------------------------------LDGTQKTIIALGIACGMARLHSF------NIMHRDLKSLNILLDESYF-----------PRICDFG--- |. |. ... |||||. ||| |. |||| |.|..|.. .|.||| DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR -----ASRIKSAESELVTQNIGTVH--------------------------WMAPEMFD---------STNYTLAVDVYAYAILLWELLA--EEIPYNGY .| ... .... ... ||||| .. .| . ||... .|.||.. .| .| | QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM SV---------PQIMRTVCMN-----------DQRLTIP--QGTP--------------PNLAKLIQLCWNRDPEKRPPFDRIFKIF | ..|. ... .|. | .. | . .. |.| ||..|||.|| |. . . . SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | 85337.m00291.AA | Pkinase | 22-273 | 24 | 1.7e-51 | 182.22 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 22-273 Range on HMM: 1-293/293 Sequence Identity: 24% (72 aa) FQYEKKIGGGSFGDVYLAKYIPTGQMTAVKELKHETLEEPFLQYFLR--EIRILAKCDNYFLLHFTGYTATHPFLI-VTEYIQNG----SLFDSLH-DQT .. ..||| |||| ||... . ||.. |||..| .. .. ..|. .| ||.|..... . . . .. ... . |.|| ..| .||| .. .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH KSL--DGTQKTIIALGIACGMARLHSFNIMHRDLKSLNILLDESYFP----RICDFGASRIK-SAESELVTQNIGTVHWMAPEMFD-STNYTLAVDVYAY ... . . ... |..|.. .|| .|.|||||. |||.|. . . .||||| .. . .. | || ..|||| .. |. .||.... GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC AILLWELLAEEIPYNGY------SVPQIMRTVCMNDQRLTIPQGTP-------------------PNLAKLIQLCWNRDPEKRPPFDRIFKI--F ..|.|.| . |. | . |... . . . . .|. . ... ..| |...||.||| .. |.. | GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | 85337.m00291.AA | UTK | 22-273 | 26 | 8.3e-49 | 165.1 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 22-273 Range on HMM: 1-296/296 Sequence Identity: 26% (78 aa) FQYEKKIGGGSFGDVYLAKYIPTG-----QMTAVKELKHETLEEPFLQ---YFLREIR---ILAKCD-NYFLLHFTGY-TATHPFLIVTEYIQNGSLFDS | ...| | ||.|..|.. . . |||...|. . . .|..| | ...... . .| . |. |. |..||||| .||.| . VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY LHDQTKSLD-------GTQKTIIALGIACGMARLHSFNIMHRDLKSLNILLDES-------YFPRICDFG---ASRIKSA--------ESELVTQN---I | ....... .|.. |. ||.||. ||| .. |||| |.|.... .. .|.||| || .. ||...... . LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR GTVHWMAPEMFDST-NYTLAVDVYAYAILLWELLAE-EIPYNGYSVPQIMRTVCMND-QRLTIPQGTPPNLAKLIQLCWNRDPEKRPPFDRIFKIF .. ||||| ... .|.. ||... ...||... || |.| .|. || . .|. |.. | .. .| . ||. ||..|| |... . . WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM |
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Kinase | 85337.m00291.AA | Dicty4-Unclassified | 22-273 | 32 | 1.8e-48 | 164.13 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 22-273 Range on HMM: 1-263/263 Sequence Identity: 32% (88 aa) FQYEKKIGGGSFGDVYLAKYIPTGQMTAVKELKHETLEEP--FLQYFLREIRILAKCDNYFLLHFTGYTATHP------FLIVTEYIQNGSLFDSLH--- | . || | | |. | . | ||| . .| |..|. || |. || . | . ||.| . | || | IQIDQFIGKGHFSKVH--KGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGY-CINPRSHKSTMCIVMEFMHKGNLFEVIHSKP ---DQTKSLDGTQKTIIALGIACGMARLHSFNIMHRDLKSLNILLDESYFPRICDFGASRIKSAESELVTQNIG-TVHWMAPEMFDSTNYTLAVDVYAYA .| .|| | .|. || ||. ||. |. |||.|| |||.| . .| ||| || . . | |. |. | .|| |. . ||| || SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTT--IAGTPKWESPECLMHESYNQKSDVYSYA ILLWELLAEEIPYNGYS-VPQIMRTVCMNDQRLTIPQGTPPNLAKLIQLCWNRDPEKRPPFDRIFKIF ..|.||. . || . . . | || | || .... ||| || || ||| .. | . MMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL |
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Kinase | 85337.m00291.AA | LRRK | 91-275 | 34 | 1.2e-43 | 151.34 | In-house | 128-351 (351) | Show / Hide |
Range on Protein: 91-275 Range on HMM: 128-351/351 Sequence Identity: 34% (77 aa) HPFLIVTEYIQNGSLFDSLHDQTKS--------LDGTQKTIIALGIACGMARLHSFN--IMHRDLKSLNILLDESYFP------------RICDFGASR- ||. .|.||...|.| . ||. .. .. . | ||| || ||. |||.| | |||||| |||| .| . |.||| || HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRM IKSAESELVTQNIGTVHWMAPEMFDST---NYTLAVDVYAYAILLWELLAEE-IPYNGYS-VPQI--MRTVCM---NDQRLTIPQG-TPP-----NLAKL .. .... |. ||||| . .|| ||.|.....||||| . .|. ... . .. | .. . .| |||| || . .| FQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDL IQLCWNRDPEKRPPFDRIFKIFKS ||.||. ||.||| | |.|. .. IQHCWQHDPKKRPHFSQIVKRLSQ |
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Kinase | 85337.m00291.AA | LRRK | 22-54 | 21 | 7.9e-05 | 12.99 | In-house | 1-60 (351) | Show / Hide |
Range on Protein: 22-54 Range on HMM: 1-60/351 Sequence Identity: 21% (13 aa) FQYEKKIGGGSFG-DVYLAKYI--------------------------PTGQMTAVKELK . .|..|| |.|| || ||.. .|..|.| .. LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWN |