97466.m00043

Species: T.vaginalis
Alias: 97466.m00043, TvagK0614
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7-like

Sequence

Name Sequence Type Origin Length Description Download
97466.m00043.AA Protein None 347 None Fasta, JSON
97466.m00043.kin_dom Protein Kinase Domain None 295 None Fasta, JSON

Protein domain

Protein domains of 97466.m00043.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 97466.m00043.AA CMGC 15-309 21 8.6e-91 298.51 In-house 1-513 (513) Show / Hide
Range on Protein: 15-309
Range on HMM: 1-513/513
Sequence Identity: 21% (110 aa)

FRIIENIGVGAYGSVFKAFD--------------LETNEVVALKILK-AYDQKES---------LPLSFYRELGVLQNFK-----------------HEN
. ||. || |.|| |.|..|               ||||.||.|..| .   .|          .| . .||.  |....                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVSYGGVFRYPH-----------------EICITLEYCETDLQKQLSCQP---------LLQPNQ------------VKHLM------RQLLSGLA--EL
||.   .|....                 ....  ||...|| . .  ..          | . .            .|..|      .|.| ||.   .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HQAG--YAHRDLKSSNILIKGGRTL--------------------KITDFGLSRQLNSK-----------------------QLTSKVTSLAYRAPELIL
|...    ||||| .||||    .|                    || ||||.|....                        ..|. | .. |||||..|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GSKDYT---------TAIDIWSAGIIFYELCTGEK---------FP----------SACSDLSQLDKIFRVTGTPS------------PSSEDEKSPEIQ
|.|.||         |.||.||.| ||.|. || .         ||          .  |.. ||.|||.| |||.            .. |.|    |.
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

SDGDILCHLPN--------WRLASMLHI-----YPRTLEQLLKDKLPP-----------------------------------ELADAFDIITSMLSLNP
 .. ..   ..        |     ..|     .|.   . .|.. |.                                   .  .|.| .  || ..|
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

SNRPSAVELLRNPFF
..|..| . |. |.|
DKRITAEQALQHPYF

Kinase 97466.m00043.AA S_TKc 15-309 25 6.5e-87 295.97 SMART 1-231 (231) Show / Hide
Range on Protein: 15-309
Range on HMM: 1-231/231
Sequence Identity: 25% (81 aa)

FRIIENIGVGAYGSVFKAFDLETNEVVALKILKAYDQKESLPLSFYRELGVLQNFKHENIVSYGGVFRYPHEICITLEYCET---DLQKQLSCQPL----
..|.. || ||.|.|.|. . .|...||.||.|          ...||. .|.. .|.||| . .||.  ..... .|||..   || . .  ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LQPNQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSRQLNSKQLTSKVTSLAYRAPELILGSKDYTT-AIDIWSAGIIFYELC
  . . .....|.|....|. .|. |  ||||| .|||.    ..||.||||.|||     |. . .. |.|||..     |.. ..|.|| |.|.||..
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

TGEK-FPSACSDLSQLDKIFRVTGTPSPSSEDEKSPEIQSDGDILCHLPNWRLASMLHIYPRTLEQLLKDKLPPELADAFDIITSMLSLNPSNRPSAVEL
.|.  ||       |....|.. |                                                     .| |.|  .|  .|..||.| |.
CGYPPFP-------QMQMMFKKIG---------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EA

LR-------NPFF
|.        |.|
LQDEWDIKCHPWF

Kinase 97466.m00043.AA CDK 15-309 30 1e-80 257.91 In-house 1-284 (284) Show / Hide
Range on Protein: 15-309
Range on HMM: 1-284/284
Sequence Identity: 30% (102 aa)

FRIIENIGVGAYGSVFKAFDLETN-----EVVALKILKAYDQ-----KESLPLSFYRELGVLQNFKHENIVSYGGVFRYP-----------HEICITLEY
. ..| || |.|| |.|| |..|.     ..|||| ..   .     || .| .  ||   |..  |.|||.   |.              . . .  ||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

CETDLQKQLSCQPLLQPNQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRT-----LKITDFGLSRQLNS--------KQLTSKVTSLAYRAPEL
...|| | ..         .|..|.|||.||. .|. .  ||||| .||||    .     |||.||||.|  ..        . .|..|  | ||||||
MDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPEL

ILGSKDYT--TAIDIWSAGIIFYELCT---GEKFPSACSDLSQLDKIFRVTGTPSPSS--EDEKSPEIQSDGDILCHLPNWRLASMLHIYPRTLEQLLKD
 ||||.|.  |.||.||.| ||.|. |   .. .    |.. ||.||||. |||....  . .| |.                                 
LLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY--------------------------------

KLPPELADAFDIITSMLSLNPSNRPSAVELLRNPFF
          | . .|| ..|..| || . |  |.|
----------DLLNKMLCYDPKKRISAEQALQHPYF

Kinase 97466.m00043.AA Pkinase 15-309 26 9.7e-75 259.41 Pfam 1-293 (293) Show / Hide
Range on Protein: 15-309
Range on HMM: 1-293/293
Sequence Identity: 26% (85 aa)

FRIIENIGVGAYGSVFKAFDLETNEVVALKILKAYDQKESLPLSFYR--ELGVLQNFKHENIVSYGGVFRYPHEICITLEYCET-----DLQKQLS--CQ
..|.. || |..|.|.|. .  |...||.||.|  ..|.. . .  |  |. ......|.||| . ..|... .|.. .||||      ||   .|   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PLL--QPNQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIK-GGRT---LKITDFGLSR---QLNSKQLTSKVTSLAYRAPELILGSKDYTTAIDIWSA
  .  .....|. |.|.|.||. .|. |  |||||..||||.  | .   .||.||||..     |.  .|. . .. |.|||.|.|...|....|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIIFYELCTGEKFPSAC----SDLSQLDKIFRVTGTPSPSSEDEK-----SPEIQSDGDILCHLPNWRLASMLHIYPRTLEQLLKDKLPPELADAFDIIT
|.|.||...|.   . .    . ..|. .|.|. |.| .......     .. ..                          . .. . .    .. |.|.
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---------------------F-HWTF-HNWSEECKDFIK

SMLSLNPSNRPSAVELLRNPFF
..| ..|. ||.| ..|  |.|
WCLCKDPKKRPTAEQILQHPWF

Kinase 97466.m00043.AA CDC2 15-309 34 1.3e-73 225.51 In-house 1-301 (301) Show / Hide
Range on Protein: 15-309
Range on HMM: 1-301/301
Sequence Identity: 34% (107 aa)

FRIIENIGVGAYGSVFKAFDLETNEVVALKILKAYDQKES--LPLSFYRELGVLQNFK-HENIVSYGGVFRYPHEICITLEYCETDLQKQLS-CQPL---
.  || || | || |.|. |..||..||||  .   . |    | .  ||.  |.. | |.|||.   |.   . . .  ||.. || | .   .|    
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

LQPNQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSR--QLNSKQLT--SKVTSLAYRAPELILGSKDYTTAIDIWSAGIIFYEL
..|. || .| |.|.|.. .|| .  ||||| .||||    ..|| ||||.|  . .....|    |  | |||||. ||.|.|.|..|.|| | ||.|.
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---CTGEKFPSACSDLSQLDKIFRVTGTPSPSSEDEKSPEIQSDGDILCHLPNWRLASMLHIYPRTLEQLLKDKLPPELA-DAFDIITSMLSLNPSNRPS
   .| . . .. |   || ||||. |||.    ... |.. .  |     |.|.   . .| |. ...    ..  .|  ...|.. .|| ..|..| |
FMDVTKKPLFHGDSEIDQLFKIFRILGTPN----EQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKK---KNQ-SCLDPEGIDLLMQMLQYDPQKRIS

AVELLRNPFF
| | |..|.|
AKEALQHPYF

Kinase 97466.m00043.AA CDK5 15-309 34 4.1e-61 191.66 In-house 1-287 (287) Show / Hide
Range on Protein: 15-309
Range on HMM: 1-287/287
Sequence Identity: 34% (104 aa)

FRIIENIGVGAYGSVFKAFDLETNEVVALKILKAYDQKESLPLSFYRELGVLQNFKHENIVSYGGVFRYPHEICITLEYCETDLQKQL-SCQPLLQPNQV
.  .| || | || |.|| . || |.||||  .  .  |  | .  ||  .|.  ||.|||    |      . .  |.|  || | . ||.  .... .
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

KHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSRQ--LNSKQLTSKVTSLAYRAPELILGSKDYTTAIDIWSAGIIFYELC-TGEKFP
| .| ||| |||  |.    |||||  | ||    .||  |||| |      .  .. |  | ||.|   .||| |.| ||.||.| || |.  .|    
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

SACSDLSQLDKIFRVTGTPSPSSEDEKSPEIQSDGDILCHLPNWR-LASMLHIYPRTLEQLLKDKLPPELADAFDIITSMLSLNPSNRPSAVELLRNPFF
   ..  || .||...|||.     .| | |        .||... ..  . .||  ..| ..   |   .   |.   || .||  | || . |. |.|
PGNDVEDQLKRIFKIMGTPC----EDKWPSI-------TKLPDYKPNHQQYPMYP--AHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF





Kinase 97466.m00043.AA Ciliate-E2 15-309 17 3e-57 195.06 In-house 1-365 (365) Show / Hide
Range on Protein: 15-309
Range on HMM: 1-365/365
Sequence Identity: 17% (74 aa)

FRIIENIGVGAYGSVFKAFDLETNE-----------------------VVALKILKAYDQKESLP-LSFYRELG----------VLQNFKHENIVSYGGV
. .|. || |..|||.|. . ....                        .|.||.| .. .. .  .. .||.           .|.. .| ||. .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FR--YPHEICITLEYCET-DLQK-----QLSCQPLLQ------PNQVKHLMRQLLS---------------GLAELHQAG-YAHRDLKSSNILIKGGRTL
|     . | . .|||.  ||..     .....  ..       ...|..|.|.|.               .| .||. .   |||.| .|||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KITDFGLSRQLNSK---------------------------------QLTSKVTSLAYRAPELILG--------SKDYTTAIDIWSAGIIFYELCTGEK-
||.|||||.... .                                 .  . . .. | ||| . |        .|.|....||||.|.|.||...|.  
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FPSACSDLSQLDKIFRVTGTPSPSSEDEKSPEIQSDGDILCHLPNWRLASMLHIYPRTLEQLLKDKLPPELA---------------------DAFDIIT
|                                                         ..| .. |.    .                     .. |.| 
F---------------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIK

S----MLSLNPSNRPS-AVELLRNPFF
     ||  .|..|.. . ..| .|.|
KFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 97466.m00043.AA MAPK 15-231 32 1.2e-53 183.84 In-house 1-256 (328) Show / Hide
Range on Protein: 15-231
Range on HMM: 1-256/328
Sequence Identity: 32% (83 aa)

FRIIENIGVGAYGSVFKAFDLE------TNEVVALKILKAYDQKESLPLSFYRELGVLQNF-KHENIVSYGGVFRY------PH-----EICITLEYCET
..|...|| |||| |..|.| .      ... ||.| .    |.. .    |||.  |. | .||||..   .|.       ..     .|.|  |..||
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLQKQLSCQPLLQPNQVKHLMRQLLSG--LAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSRQLNSK----------------QLTSKVTSLAYRAP
||.. . .|. |    .. .| |.| |  |  .| |.  ||||| ||||.    .||| ||||.|.. ..                ..|  |.   ||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

ELILG--SKDYTTAIDIWSAGIIFYELCT-GEKFPSACSDLSQLDKIFRVTGTPSP
|..|.  ...||.|.|.||.| || |. | .  .    . . |. .|. |.||||.
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSE

Kinase 97466.m00043.AA CDK-DD1 15-229 36 1.2e-52 160.59 In-house 1-219 (379) Show / Hide
Range on Protein: 15-229
Range on HMM: 1-219/379
Sequence Identity: 36% (80 aa)

FRIIENIGVGAYGSVFKAFDLETNEVVALKILKAYDQKESLPLSFYRELGVLQNFKH-ENIVSYGGVFRYP--HEICITLEYCETDLQKQLSCQP-LLQP
. ||. .| | |||||||    | . ||||. |   | . .|     |   |.  .|  |||     |      .  . .|| | || | .| .   .  
YQIISKCGQGIYGSVFKAIHKITHCMVALKNFKDWNQEDGEP---KVECKYLMQLRHCKNIVHLIDHFYNFKNSKYVMVFEYFEHDLWKFMSNHQCYMSL

NQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSRQLNS---KQLTSKVTSLAYRAPELILGSKDYTTAIDIWSAGIIFYELCTGE
 ..|  ..||| |. |.| .|  ||| | .| ||     |||||||..        | . ..| || ||.||| .||  |   ||.|| | |  |. |. 
PCIKCFFHQLLEGINECHNQGIMHRDIKPANLLINNRGDLKITDFGFTTYYTKRSEKHFSHQVVSLWYRPPELLMGSCQYGPEIDMWSVGCILMEMITNF

KFPSACSDLSQLDKIFRVTGTP
 .    ..  ||. |.   |.|
YMFAGSNEQQQLELICKLCGCP

Kinase 97466.m00043.AA STE 15-207 24 2.2e-49 170.35 In-house 1-265 (359) Show / Hide
Range on Protein: 15-207
Range on HMM: 1-265/359
Sequence Identity: 24% (68 aa)

FRIIENIGVGAYGSVFKAFDL------ETNEV---------VALKILK-----AYDQK-----------ESLPLSFYRELGVLQNFK--HENIVSYGGVF
...|| || ||.|.|.|| .       .|.||         .| |...     ..| .           ..   .. .|. ......  |.||| | | .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

RYP-------HEICITLEYCE-TDLQKQLS-CQPLLQP-------------NQVKHLMRQLLSG-LAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLS
 .        .|..| .||..   | . .  .   ..|             .|...  ||.| | |. ||. .. |||.|..|||.      |..|||..
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

RQLNS-------------------KQLTSKVTSLAYRAPELILG-----SKDYTTAIDIWSAGIIFYELCTGE
 ||..                   |  |   |   . ||| |..     .|.|.|  |||| |.   |..||.
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP--WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK

Kinase 97466.m00043.AA CRK7 110-233 31 8.2e-39 131.35 In-house 111-276 (343) Show / Hide
Range on Protein: 110-233
Range on HMM: 111-276/343
Sequence Identity: 31% (52 aa)

PNQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSRQLNS----KQLTSKVTSLAYRAPELILGSKDY------------------
..|.|..|.||| |.. .|. .  |||.| ||||.     .||.|||| | .||    ...| .|  | ||.||| || . |                  
HQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKELIRNIKSIQL

--------------------TTAIDIWSAGIIFYELCTGEKFPSACSDLSQLDKIFRVTGTPSPSS
                    ...||.|| | |. || |..    .   . ||.||... |.| | .
SLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNN

Kinase 97466.m00043.AA PITSLRE 109-309 37 2.3e-38 133.76 In-house 104-295 (295) Show / Hide
Range on Protein: 109-309
Range on HMM: 104-295/295
Sequence Identity: 37% (78 aa)

QPNQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSR--QLNSKQLTSKVTSLAYRAPELILGSKDYTTAIDIWSAGIIFYELCTG
.| ..| || |||.| . .|     ||||| ||.|.     ||| |||| |  . . | .|. |  | |||||| ||.| |.|..|.|| | || |. |.
KPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEFITM

EKFPSACSDLSQLDKIFRVTGTPSPSSEDEKS-PEIQSDGDILCHLPNWRLASMLHIYPRTLEQLLKDKLP--PELAD-AFDIITSMLSLNPSNRPSAVE
.      |.. |...||   |||.     ||. | ...       ||.|..   .  ||   .  |. . |    . | .||    || .|| || .| .
KPLFQGKSEIDQINCIFKEMGTPT-----EKIWPGWTE-------LPHWKMMNNFPHYP---YNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASD

LLRNPFF
 |  |.|
ALKHPWF

Kinase 97466.m00043.AA Pkinase_Tyr 15-210 27 1.4e-23 80.49 Pfam 1-214 (270) Show / Hide
Range on Protein: 15-210
Range on HMM: 1-214/270
Sequence Identity: 27% (60 aa)

FRIIENIGVGAYGSVFKAFDL----ETNEVVALKILKAYDQKES-LPLSFYRELGVLQNF-KHENIVSYGGVFR--YPH-EICITLEYCET-DLQKQLSC
 .... .| ||.|.|.|.       .|.  || |.|| .  .|  .  .| ||. .. .. .|.|||.. ||      . .|.| .||..  || . |  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----QPLLQPNQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSRQL----NS-KQLTSKVTSLAYRAPELILGSKDYTTAIDIWS
    .. | . .  .  .|  .|.. |.. .. ||||   |.|.. ... ||.||||.| .    .  .. ..        ||| |  .| .||. |.||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVWS

AGIIFYELCTGEKFP
 |.  .|..|  . |
FGVLMWEIFTYGEQP

Kinase 97466.m00043.AA TyrKc 15-309 21 7.2e-17 50.07 SMART 1-280 (280) Show / Hide
Range on Protein: 15-309
Range on HMM: 1-280/280
Sequence Identity: 21% (73 aa)

FRIIENIGVGAYGSVFKAFDLETNEVVALKILKAYDQKESLPLSFYRELGVLQNF--KHENIVSYGGVFRYP-------HEICITLEYCET-DLQKQL-S
 . .. .| ||.| |.|.      . || | ||..         |.||. .. ..  .|.|||   || . .       . ..| .||..  ||.. | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

CQPLLQPNQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSRQLNSK-------QLTSK----VTS--LAYR--APELILGSKDYT
..| |.. .  . . |  .| . ||. .. ||||   |.|.. ..| ||.|||||| . ..       .  .|     .   | .|  ||| |  .| .|
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK-FT

TAIDIWSAGIIFYELCTGEKFPS--------ACSDLSQLDKIFRVTGTPSP----SSEDEKSPEIQSDGDILCHLPNWRLASMLHIYPRTLEQLLKDKLP
|. |.|| |.  .|..|  . |           ... .. |  .    |      |                                           .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------------------------------FV

PELADAFDIITSMLSLNPSNRPSAVELLRNPFF
   .. ..|...    .|..||.  |.    .|
CCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 97466.m00043.AA CRK7 15-75 39 8.7e-15 47.23 In-house 1-64 (343) Show / Hide
Range on Protein: 15-75
Range on HMM: 1-64/343
Sequence Identity: 39% (25 aa)

FRIIENIGVGAYGSVFKAFDLETNEVVALKILKAYDQ---KESLPLSFYRELGVLQNFKHENIV
...|. || | || | || ...|.| |||| ..  .    ||  |    ||  .|. ..|.|||
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIV

Kinase 97466.m00043.AA PITSLRE 15-76 40 5.5e-14 47.47 In-house 1-65 (295) Show / Hide
Range on Protein: 15-76
Range on HMM: 1-65/295
Sequence Identity: 40% (26 aa)

FRIIENIGVGAYGSVFKAFDLETNEVVALKILKAY--DQKESLPLSFYRELG-VLQNFKHENIVS
| ..  |. |.|| |..| | .|.|.|||| ||      ||  |.   ||   .|   .|.|||.
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVN

Kinase 97466.m00043.AA CDK-DD1 279-309 38 3.3e-07 17.64 In-house 349-379 (379) Show / Hide
Range on Protein: 279-309
Range on HMM: 349-379/379
Sequence Identity: 38% (12 aa)

LADAFDIITSMLSLNPSNRPSAVELLRNPFF
| .  |.|  || |.| .| .. | |  |.|
LPSFLDLIERMLTLCPKKRINTKEALQHPWF

Kinase 97466.m00043.AA STE 281-309 35 6e-06 17.05 In-house 329-359 (359) Show / Hide
Range on Protein: 281-309
Range on HMM: 329-359/359
Sequence Identity: 35% (11 aa)

DAFDIITSMLSLNPSNRPSAVELLR--NPFF
.  | |   |  .|..||.| .||.   ||.
EFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase 97466.m00043.AA MAPK 281-309 34 2.3e-05 14.26 In-house 300-328 (328) Show / Hide
Range on Protein: 281-309
Range on HMM: 300-328/328
Sequence Identity: 34% (10 aa)

DAFDIITSMLSLNPSNRPSAVELLRNPFF
.| | .  || ..|. | .. | |. |.|
QAIDLLEKMLVFDPDKRITVEEALQHPYF

Kinase 97466.m00043.AA CRK7 280-309 33 7.8e-05 12.37 In-house 314-343 (343) Show / Hide
Range on Protein: 280-309
Range on HMM: 314-343/343
Sequence Identity: 33% (10 aa)

ADAFDIITSMLSLNPSNRPSAVELLRNPFF
....|    || |.|. | .| | |. ..|
KECLDLLDKMLCLDPKKRFTAEECLQHDWF