Gene 93440.m00455 (T.vaginalis)

93440.m00455

Species: T.vaginalis
Alias: TvagK0971, 93440.m00455
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: YAK

Sequence

Name Sequence Type Origin Length Description Download
93440.m00455.AA Protein None 431 None Fasta, JSON
93440.m00455.kin_dom Protein Kinase Domain None 321 None Fasta, JSON

Protein domain

Protein domains of 93440.m00455.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93440.m00455.AA DYRK 67-387 30 3.3e-72 246.22 In-house 1-320 (320) Show / Hide 
Range on Protein: 67-387
Range on HMM: 1-320/320
Sequence Identity: 30% (100 aa)

FRVIDTLGNGTFSYVYKCQLLGDIHSFFAMKIIKNLPQYHATGISEVSLHQLLSSAPDHPGKSHIIMPISSFEMDNHVIIVEPLLFRSLFEGIYQNRPVS
..... .| |.|. | ||.     .  .|.|||.| . .| ... |... ..|. . |   |.|..    .|   ||. ||  ||  .|.| . .|.   
YEILEYIGKGSFGQVVKCWDH-KTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQ-DPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQG

Q-LLSTIRNIMEQILQGVSFLHAN-GVTHCDLKPDNVLFDDE-NMNNLQIIDLGSASMSPTGAGDYIQSRFYRSPEVILGLPYTNKIDLWSAGCIASELF
   |. .| .  |||..  ||| |    ||||||.|..  .. | ... .|| ||..        ||||||||.||||||.||  .|| || |||  |||
FFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELF

LNFAIFATNTEFDTIHSMVALLGPFPDSMIQPS--KQWWKFFDMTRDGYKLKMDPNDVLLERHL----YNSIFQETGPSSLENLIMNHCDLETDDDVNLV
.   .|. ..|.| .  .. .||..|  ||. .  .   ||||       ....  |   ..      |. ...       .... .. ...  ..   .
TGWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC------FMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQ-CDD

SCFSHFCQSLLQFDPNTRLSAEQALSHPFI
..| .| . .||.||. |....||| ||..
HQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase 93440.m00455.AA CMGC 67-387 17 5.6e-72 235.54 In-house 1-513 (513) Show / Hide 
Range on Protein: 67-387
Range on HMM: 1-513/513
Sequence Identity: 17% (92 aa)

FRVIDTLGNGTFSYVYKCQL-------------LGDIHSFFAMKIIKNLPQYHATGI-------------SEVSLHQLLSSA----------PDHPGKSH
. .|. .| ||.. ||||.              . .   . |.|.||| . |. ..               |... . |. .          ||.. . .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIMPISSFEMDN-----------------HVIIVEPLLFRSLFEGIYQNR---------PVSQLL----------STIRNIM------EQILQGVS--FL
|.  . .|  .|                 |. .|  ..  .|.. |..|.         | |.             .|...|       |||.|.   ..
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HANG--VTHCDLKPDNVLFDDENMN------------------NLQIIDLGSASMSPTG------------------------AGDYIQSRFYRSPEVIL
| ..  . |.|||| |.|..... .                  .| |.| |.|    .                           .|...|.||.||..|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GLP----------YTNKIDLWSAGCIASELFLN--------FAIFATNTE-----------FDTIHSMVALLGPFPDSMIQP----------SKQWWKFF
| .          || .|| ||.|||  |....          .| ...|            | .. .. .||... .|||           ...| .. 
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPNMI

DMTRDGYKLKMDP-------NDVLLERHLYNSI-FQETGPSSLENLIMNHCDLETDDDVN--------------------------LVSCFSHFCQSLLQ
.. .   ..| ..        .    ... . . |..  | ...||. .| .. .    .                          . . . .. . .||
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDD-N-NKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQ

FDPNTRLSAEQALSHPFI
.||. |..|||||.||..
YDPDKRITAEQALQHPYF
Kinase 93440.m00455.AA S_TKc 67-387 19 3.1e-54 187.4 SMART 1-231 (231) Show / Hide 
Range on Protein: 67-387
Range on HMM: 1-231/231
Sequence Identity: 19% (65 aa)

FRVIDTLGNGTFSYVYKCQLLGDIHSFFAMKIIKNLPQYHATGISEVSLHQLLSSAPDHPGKSHIIMPISSFEMDNHVIIVEPLLFR---SLFEGIYQNR
.......| |.|. ||||.  .  .  .|.||||       . ..|.....      .||   .|.  . .|.  .|. .|  ..     .||. | ...
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK------EHIRREIQILKK-----HHP---NIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

P----VSQLLSTIRNIMEQILQGVSFLHANGVTHCDLKPDNVLFDDENMNNLQIIDLGSASMSPTGAGDYIQSRFYRSPEVILGLPYTN-KIDLWSAGCI
.    .     ..| .| ||.... ..| .|. |.||||.|.|.|.    .. |.| |.|         .. ...|..|||.   .|.  |.| || |||
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

ASELFLNFAIFATNTEFDTIHSMVALLGPFPDSMIQPSKQWWKFFDMTRDGYKLKMDPNDVLLERHLYNSIFQETGPSSLENLIMNHCDLETDDDVNLVS
  |..     |   ... ... ..                                                                           .
LYEMLCGYPPFP--QMQMMFKKIG--------------------------------------------------------------------------SP

CFSHFCQSLLQFDPNTRLSAEQALS-------HPFI
 . .| . .||.||. |..| .||        ||..
EAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 93440.m00455.AA YAK 67-303 36 5.9e-50 167.72 In-house 1-239 (347) Show / Hide 
Range on Protein: 67-303
Range on HMM: 1-239/347
Sequence Identity: 36% (88 aa)

FRVIDTLGNGTFSYVYKCQLLGDIHSFFAMKIIKNLPQYHATGISEVSLHQLLSSAPDHPGKS---HIIMPISSFEMDNHVIIVEPLLFRSLFEGIYQNR
. | | || |||  | ||| . |    || |.||| . |   .. |. . ..|    |  .|    ||.  . .|   ||  .|  .|  .|.| . ||.
YIVLDMLGQGTFGQVVKCQNC-DTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNK

PVSQLLSTIRNIMEQILQGVSFLHANGVTHCDLKPDNVLFDDENMNNLQIIDLGSASMSPTGAGDYIQSRFYRSPEVILGLPYTNKIDLWSAGCIASELF
      . ||    ||| |   |    . |||||| |..    |   ..||| ||.      .  |||.|.|||||.|.. .|.  || || |||  |||
FCGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELF

LNFAIFATNTEFDTIHSMVALLGPFPDSMIQPSKQWWKFF
|   ||  | |.. |   .  || .|  ||   .   |.|
LGLPIFPGNSEYNQIKRIIDMLGYPPSWMIDQGRFKNKYF
Kinase 93440.m00455.AA HIPK 67-387 28 1.9e-45 140.8 In-house 1-329 (329) Show / Hide 
Range on Protein: 67-387
Range on HMM: 1-329/329
Sequence Identity: 28% (94 aa)

FRVIDTLGNGTFSYVYKCQLLGDIHSFFAMKIIKNLPQYHATGISEVSLHQLLSSAPDHPGKSHIIMPISSFEMDNHVIIVEPLLFRSLFEGIYQNRPVS
. |.. || |||  | ||   |  .   |.||.|| | |   |  |||. . ||.    .   |..     |.  ||. .|  .|   |..   ||.   
YEVLEFLGRGTFGQVVKCWKRG-TNEMVAIKILKNHPYYARQGQIEVSILHCLSQ--ENADEYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMP

QLLSTIRNIMEQILQGVSFLHANGVTHCDLKPDNVLFDDENMN--NLQIIDLGSAS-MSPTGAGDYIQSRFYRSPEVILGLPYTNKIDLWSAGCIASELF
  |  || |..|.|     |   |. | ||||.|..  |.        .|| |||| .| .    |.|||.|| ||.|||||.  ..| || ||.  |||
LPLKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELF

LNFAIFATNTEFDTIHSMVALLGPFPDSMIQPSKQWWKFF----DMTRDGYKLKMDPNDVLLERHLYNSIFQETGPSSLENLIMNHCDLETDDDVNLVSC
|    .  . |.| |  .    .   .....   .  .||    ..    ..||  ... . .  .     .  .  .|     .   .. .    .|  
LGWPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFDRDKQSKFRPWRLKH-IEEHEQQTSVKSKEARKYIFNCLDDMPEVNMLVDPERQDYRVEK

-----FSHFCQSLLQFDPNTRLSAEQALSHPFI
     |.|    ..  |.. |..  .|| |||.
IDRREFVHVLKKMCTWDAHKRITPCEALNHPFV
Kinase 93440.m00455.AA DYRK2 67-270 34 6e-39 124.06 In-house 1-203 (318) Show / Hide 
Range on Protein: 67-270
Range on HMM: 1-203/318
Sequence Identity: 34% (70 aa)

FRVIDTLGNGTFSYVYKCQLLGDIHSFFAMKIIKNLPQYHATGISEVSLHQLLSSAPDHPGKSHIIMPISSFEMDNHVIIVEPLLFRSLFEGIYQNRPVS
. .   .| | |  | || . .  . . | |.| |   .| .   |.   . ...  |  . . ..    .|   ||..|.  ||  .| | | .| .  
YEILEVIGKGSFGQVVKC-YDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQ-DKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQG

QLLSTIRNIMEQILQGVSFLHANGVTHCDLKPDNVLFDDENMNNLQIIDLGSASMSPT-GAGDYIQSRFYRSPEVILGLPYTNKIDLWSAGCIASELFLN
  |. .|    .|||. .||| | . |||||| |.|   .| ... .|| ||           ||||||||.||||||..|   ||.|| |||. ||.  
FSLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTG

FAIFA
. .|.
YPLFP
Kinase 93440.m00455.AA Pkinase 67-269 27 4.9e-38 135.56 Pfam 1-212 (293) Show / Hide 
Range on Protein: 67-269
Range on HMM: 1-212/293
Sequence Identity: 27% (61 aa)

FRVIDTLGNGTFSYVYKCQLLGDIHSFFAMKIIKNLPQYHATGIS-----EVSLHQLLSSAPDHPGKSHIIMPISSFEMDNHVIIVEPLLFR-----SLF
.... ..| |.|. ||||.  |. .  .|.||||   . .   ..     |..... |.    ||   .|.  . .|| ..|. .| ...       .||
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN----HP---NIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF

EGIY--QNRPVSQL-LSTIRNIMEQILQGVSFLHANGVTHCDLKPDNVLFDDENMNN---LQIIDLGSA----SMSPTGAGDYIQSRFYRSPEVIL-GLP
. |   ...... .   .....| |||.|. ..|..|. |.||||.|.|.| .|...   . |.| |.|      . . . ..  ...|..||||. | .
DYISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQY

YTNKIDLWSAGCIASELFLNFAIF
|. |.| ||.|||  |...   .|
YGPKVDMWSCGCILYEMLCGRPPF
Kinase 93440.m00455.AA DYRK1 67-309 31 1.9e-36 125.23 In-house 1-243 (321) Show / Hide 
Range on Protein: 67-309
Range on HMM: 1-243/321
Sequence Identity: 31% (76 aa)

FRVIDTLGNGTFSYVYKCQLLGDIHSFFAMKIIKNLPQYHATGISEVSLHQLLSSAPDHPGKSHIIMPISSFEMDNHVIIVEPLLFRSLFEGIYQNRPVS
. ..  .| | |  | |       . . |.|||||   .      |. |  |.  . |.  | .|.     |   ||. .|  ||   |.. .       
YEIDSLIGKGSFGQVVKA-YDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKH-DKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRG

QLLSTIRNIMEQILQGVSFLHAN--GVTHCDLKPDNVLFDDENMNNLQIIDLGSASMSPTGAGDYIQSRFYRSPEVILGLPYTNKIDLWSAGCIASELFL
  |  .| . .|... . |. .    . ||||||.|.|        ..||| ||.  .      ||||||||||||.||..|  .||.|| |||  |.  
VSLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHT

NFAIFATNTEFDTIHSMVALLGPFPDSMIQPSKQWWKFFDMTRDG
   .|.   | | .. .|  ||  |. ||. . .  |.|. . |.
GEPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYFEKDPDN
Kinase 93440.m00455.AA DyrkP 67-294 31 7.8e-33 104.96 In-house 1-230 (323) Show / Hide 
Range on Protein: 67-294
Range on HMM: 1-230/323
Sequence Identity: 31% (73 aa)

FRVIDTLGNGTFSYVYKCQLLGDIHSFFAMKIIKNLPQYHATGISEVSLHQLLSSAPDHPGKSHIIMPISSFEMDNHVIIVEPLLFRSLFEGIYQNRPVS
. ... ||   ||   .|| .      . |||| |   |    | |. | . .    |   |  ..     |    |. |.  ||   |.|    ||   
YQIMEYLGSAAFSKAIQCQDK-QTNQMMCMKIIENNKDYFDQSIDEIKLLRYINYNGDVDEK-NVLRYYDYFYHKEHLFIITELLKDNLYEFYKFNRENE

Q----LLSTIRNIMEQILQGVSFLHANGVTHCDLKPDNVLFDDENMNNLQIIDLGSASMSPTGAGDYIQSRFYRSPEVILGLPYTNKIDLWSAGCIASEL
|     .  .  |  ||| .. ..|.  . ||||||.|.|       . .||| ||.         |.||| || ||||.|  |  .||.|| |||  ||
QQRYFTVGRLQKITQQILIALDYIHSLRLIHCDLKPENILMKSYPKCQVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAEL

FLNFAIFATNTEFDTIHSMVALLGPFPDSMIQ
.    .|   .    .  .. ..||||. |.|
WTGNVLFQNDNIQGLLARVIGIIGPFPEWMMQ
Kinase 93440.m00455.AA CLK 67-206 26 5.6e-28 80.38 In-house 1-150 (350) Show / Hide 
Range on Protein: 67-206
Range on HMM: 1-150/350
Sequence Identity: 26% (40 aa)

FRVIDTLGNGTFSYVYKCQLLGDIHSFFAMKIIKNLPQYHATGISEVS--LHQLLSS-APDHPGKSHIIMPISSFEM-DNHVIIVEPLLFRSLFEGIYQN
. ...||| |||. |..|.      .. | |||.|  .|     .|..  . ..     |.    .|..  ...|.   .|. ||  |. .|... .  |
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

R------PVSQLLSTIRNIMEQILQGVSFLHANGVTHCDLKPDNVLFDDE
.        .  ...||..  |... | ||| .. || |||| | .| |.
NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICFVDS
Kinase 93440.m00455.AA CAMK 72-258 19 5e-27 83.54 In-house 1-323 (425) Show / Hide 
Range on Protein: 72-258
Range on HMM: 1-323/425
Sequence Identity: 19% (63 aa)

TLGNGTFSYVYKCQLLGDI-----------HSFFAMKIIKN-----------------------------LPQYHATGISEVSLHQLLSSAP---DHPGK
||| |.|. |..|.   .            .  .|.|||.                               |.  .   .|......|..     |||  
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHP--

SHIIMPISSFEM-------------------DNHVIIVE--------PLLFRSLFEGIYQNRP-------------VSQLLSTIRNIMEQILQGVSFLHA
 .||  .  .|                    |.|...|           ||  ||. | ....                  .  | .. ||...| ..| 
-NIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHS

NGVTHCDLKPDNVLFDDENM---------------NNLQIIDLGSASMSPTG--------------------------AGDYIQSRFYRS-PEVILG---
... |.||||.|.|.|| |                ||. ||| | | . . |                            ..  .  | . |||..|   
HNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH

-----------LPYTNKIDLWSAGCI
            .|. |.| ||.|.|
CNMQNATDEEKPYYGPKCDMWSCGVI
Kinase 93440.m00455.AA PRP4 193-263 48 9.9e-21 72.64 In-house 129-199 (320) Show / Hide 
Range on Protein: 193-263
Range on HMM: 129-199/320
Sequence Identity: 48% (35 aa)

HCDLKPDNVLFDDENMNNLQIIDLGSAS-MSPTGAGDYIQSRFYRSPEVILGLPYTNKIDLWSAGCIASELF
| |.||||.|   |. | | ..| ||||  .  .   | .|||||.||.|.| || . ||.||.||   ||.
HADIKPDNILV-NESKNTLKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYELY
Kinase 93440.m00455.AA CLK 230-299 39 1.1e-19 55.09 In-house 208-283 (350) Show / Hide 
Range on Protein: 230-299
Range on HMM: 208-283/350
Sequence Identity: 39% (30 aa)

IQSRFYRSPEVILGLPYTNKIDLWSAGCIASELFLNFAIFATNTEFDTIHSMVALLG-PFPDSMIQPS-----KQW
...| || |||||||..  . | || ||| .|| . |  | |. . ..   |  ..| |.| .||| .     ||.
VSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRTRRFKVKQK
Kinase 93440.m00455.AA YAK 359-387 48 3.4e-10 30.41 In-house 319-347 (347) Show / Hide 
Range on Protein: 359-387
Range on HMM: 319-347/347
Sequence Identity: 48% (14 aa)

CFSHFCQSLLQFDPNTRLSAEQALSHPFI
|| .|   ||| .|. | .. ||  ||||
CFIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase 93440.m00455.AA CAMK 365-387 43 5.3e-09 24.4 In-house 403-425 (425) Show / Hide 
Range on Protein: 365-387
Range on HMM: 403-425/425
Sequence Identity: 43% (10 aa)

QSLLQFDPNTRLSAEQALSHPFI
...|| ||. |...||.|.||..
RKMLQVDPEKRMTIEQCLNHPWM
Kinase 93440.m00455.AA Pkinase 362-387 42 9.4e-08 28.49 Pfam 268-293 (293) Show / Hide 
Range on Protein: 362-387
Range on HMM: 268-293/293
Sequence Identity: 42% (11 aa)

HFCQSLLQFDPNTRLSAEQALSHPFI
.|. ..|..||. |..|||.| ||..
DFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 93440.m00455.AA CLK 365-387 39 1.2e-07 18.24 In-house 328-350 (350) Show / Hide 
Range on Protein: 365-387
Range on HMM: 328-350/350
Sequence Identity: 39% (9 aa)

QSLLQFDPNTRLSAEQALSHPFI
. .| .||. |... .||.||| 
RKMLEYDPSKRITCKDALQHPFF
Kinase 93440.m00455.AA DYRK2 360-387 39 1.9e-07 19.92 In-house 291-318 (318) Show / Hide 
Range on Protein: 360-387
Range on HMM: 291-318/318
Sequence Identity: 39% (11 aa)

FSHFCQSLLQFDPNTRLSAEQALSHPFI
|  | .  .. || .|....||| ||.|
FIDFIKRCFEWDPSERMTPSQALKHPWI
Kinase 93440.m00455.AA PRP4 351-387 35 1e-06 20.43 In-house 284-320 (320) Show / Hide 
Range on Protein: 351-387
Range on HMM: 284-320/320
Sequence Identity: 35% (13 aa)

DDDVNLVSCFSHFCQSLLQFDPNTRLSAEQALSHPFI
.|.   |. |  .   .|. ||  | . ..|| ||||
EDQMKKVHQFKDLLDKCLMLDPKKRITCNEALKHPFI
Kinase 93440.m00455.AA PRP4 67-150 31 7e-06 17.51 In-house 1-86 (320) Show / Hide 
Range on Protein: 67-150
Range on HMM: 1-86/320
Sequence Identity: 31% (27 aa)

FRVIDTLGNGTFSYVYKCQLLGDIHSFFAMKIIKNLPQYHATGISEVSLHQLLSSA-PDHPGKSHIIMPISSFEMDNHVIIV-EPL
.||.   | | || | .|. .       | ||| | .  | ||  |.   | |. |  |   |.|..    .|.  .|  .| |..
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECM
Kinase 93440.m00455.AA TyrKc 67-387 14 1.1e-05 -130.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 67-387
Range on HMM: 1-280/280
Sequence Identity: 14% (53 aa)

FRVIDTLGNGTFSYVYKCQLLGDIHSFFAMKI-IKNLPQYHATGISEVSLHQ---LLSSA-PDHPGKSHIIMPISSFEM--------DNHVIIVEPLLFR
 . ...||.| |  |||...         ..  .| |  ..     .  ...   ....  ..||   .|.  .             . . |..|     
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHP---NIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHG

SLFEGIYQNRPVSQLLSTIRNIMEQILQGVSFLHANGVTHCDLKPDNVLFDDENMNNLQIIDLGSASMSPTG-----AGDYI------QSR-----FYRS
.| . .  .||    ...  ... || .| ..|| ... | ||   |.| ....     | | | .     .     ..||.      ...        .
DLKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

PEVILGLPYTNKIDLWSAGCIASELFLNFAIFATN-----TEFDTIHSMVA---LLGPFPD----SMIQPSKQWWKFFDMTRDGYKLKMDPNDVLLERHL
||.|    .| | | || |    |.| . .    .      . . ..  |     . . |.    |                                  
PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------------------

YNSIFQETGPSSLENLIMNHCDLETDDDVNLVSCFSHFCQSLL----QFDPNTRLSAEQALSHPFI
                               | | .   | .     ..||. | . ..   | ..
------------------------------FVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF
Kinase 93440.m00455.AA DyrkP 360-387 39 1.6e-05 13.45 In-house 296-323 (323) Show / Hide 
Range on Protein: 360-387
Range on HMM: 296-323/323
Sequence Identity: 39% (11 aa)

FSHFCQSLLQFDPNTRLSAEQALSHPFI
|  | ...|| |   | .|  ||.||..
FIDFVRQCLQIDFTRRPTAKEALQHPWF
Kinase 93440.m00455.AA DYRK1 360-387 35 0.000181 11.05 In-house 294-321 (321) Show / Hide 
Range on Protein: 360-387
Range on HMM: 294-321/321
Sequence Identity: 35% (10 aa)

FSHFCQSLLQFDPNTRLSAEQALSHPFI
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FKDLIKRMLQYDPKQRITPYYALQHSFF