Gene 97119.m00144 (T.vaginalis)

97119.m00144

Species: T.vaginalis
Alias: 97119.m00144, TvagK0353
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
97119.m00144.AA Protein None 816 None Fasta, JSON
97119.m00144.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 97119.m00144.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 97119.m00144.AA TKL 35-279 20 1.4e-48 167.73 In-house 1-364 (364) Show / Hide 
Range on Protein: 35-279
Range on HMM: 1-364/364
Sequence Identity: 20% (76 aa)

IGAGGYGVVHHGTDKV--------TGKEVAIKQLKRERLKDALE-------------------------QKYVQEVFTTASCKDRFIVKLVGFTIEEP--
|| ||.|.|..|. .         |||.||.|..|..  .   .                         .. ..|.    ...   ||...|. ...|  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YSIIAEFLPKGPLSKVLYHRSHKERVLSPKQLTVIALGVATGLSHMRSIG--------LIHRDIKASNILLNEKNI------------
            . |. |. |.| |  .|           . |.  .||..| |.... | .        .||||.| .|||..|..             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--PTIIDFGIAQFT----NSTDTK------------------PAGTAMYMAPEVFGNS----------------RYNSSVDVFSFGMLLYEMSERHVAY-
  . | |||...|     |..||.                  . ||  .|||||. ..                 |. ..||.|||..|.|.  | . | 
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

-NHYSKEELN-------QLAQNRNVYPEFS------------SRTPIELQNLITRCWGL-PKDRPQPEEIYELF
 ..|. ....        .. ...  |.              . .| .. .|...||   |..||  .|| . .
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 97119.m00144.AA TKL-Unique 31-279 27 4.7e-44 152.67 In-house 1-290 (290) Show / Hide 
Range on Protein: 31-279
Range on HMM: 1-290/290
Sequence Identity: 27% (80 aa)

FDYEIGAGGYGVVHHGTDKVTGKEVAIKQLK-RERLKDALEQKYVQEVFTTASCK-DRFIVKLVGFTI----EEP-YSIIAEFLPKGPLSKVLY---HRS
|   ||.||||.| .|  |  |..|||||..  | .   ..|.   || .    .   .||...|...     .| ..|. |..| | | .||      .
FWNKIGEGGYGQVYKG--KWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---HKERVLSPKQLTVIALGVATGLSHMRSIG--LIHRDIKASNILLNEK------NIPTIIDFGIAQFTNSTDTKPAG------------TAMYMAPEV
    ..  |...|   .|. .| |. .  . .   ||||.| ||.|....      ||  |.|||.. | .. ......            .. .|||||
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNI-KICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

FGN--SRYNSSVDVFSFGMLLYEMSERHV------AYNHYSKEELNQLAQN--RNVYPEFSSRTPIELQNLITRCWG-LPKDRPQPEEIYELF
. .  . |. ..||.|||. |.|. .|..       | ... |.. ...    .|  |. ... | |...||..||   | .||  .||..  
LRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
S_TKc 97119.m00144.AA S_TKc 29-279 24 5.1e-43 150.14 SMART 1-231 (231) Show / Hide 
Range on Protein: 29-279
Range on HMM: 1-231/231
Sequence Identity: 24% (65 aa)

FSFDYEIGAGGYGVVHHGTDKVTGKEVAIKQLKRERLKDALEQKYVQEVFTTASCKDRFIVKLVGFTIEEPYSIIAEFLPK--GPLSKVLYHRSH--KER
. .  .|| |..|.|. ...| ||..||||..|         ..  .|.    . .  .|||| ..  .. . .. |...   | | ... .| .  . .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

VLSPKQLTVIALGVATGLSHMRSIGLIHRDIKASNILLNEKNIPTIIDFGIAQFTNSTDTKPAGTAMYMAPEVFGNSRYNS-SVDVFSFGMLLYEMSERH
.... .   ..  .. .| .. | | ||||.| .||||.|     |.|||.| .     |   ||  ||||||.    |.  ..|. |.| .||||  . 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

VAYNHYSKEELNQLAQNRNVYPEFSSRTPIELQNLITRCWG-LPKDRPQPEEIYE---------LF
  .      ..... ..           . |. ..| .|.   |..||   |. .          |
PPFP-----QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 97119.m00144.AA Pkinase 29-279 23 2.8e-39 139.94 Pfam 1-293 (293) Show / Hide 
Range on Protein: 29-279
Range on HMM: 1-293/293
Sequence Identity: 23% (71 aa)

FSFDYEIGAGGYGVVHHGTDKVTGKEVAIKQLKRERLKDALEQKYVQ--EVFTTASCKDRFIVKLVGFTI--EEPYSIIAEFLPKG----PLSKVLYHRS
. .   ||.|..|.| ....| |||.||.|..|... |.  .|  .   |.   ....  .||.| ..     ..| .. |....|     |. ..    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYIST--

HKERVL--SPKQLTVIALGVATGLSHMRSIGLIHRDIKASNILLNEKNIP----TIIDFGIA----QFTNSTDTKPAGTAMYMAPEVFG-NSRYNSSVDV
......  |....  ... .. || .. | | ||||.| .|||..... .     |.|||.|       ||  | ..||  ||||||   .. | ..||.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

FSFGMLLYEMSERHVAYNHY------SKEELNQLAQNRNVYPEFSSRTP-------------------IELQNLITRCWGL-PKDRPQPEEIYEL--F
.|.| .||||  ..  . .       .. .. ..   . .  ...   .                    |.. .|..|. . ||.|| .|.| .   |
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 97119.m00144.AA STE 29-262 18 2.7e-38 132.85 In-house 1-337 (359) Show / Hide 
Range on Protein: 29-262
Range on HMM: 1-337/359
Sequence Identity: 18% (64 aa)

FSFDYEIGAGGYGVVHHGTDKV---------------TGKEVAIKQLKRERLK---------------DALEQKYVQEVFTTASCK--DRFIVKLVGFTI
. .  .|| |..|.|. . ..                ||. .||||.. |. .               .  .|.. .|. .   |.    .|||  |  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EEP--------YSIIAEFLPKGPLSKVLYHRSHKERVLS----------PKQLTVIALGVATG-LSHMRSIGLIHRDIKASNILLNEKNIPTIIDFGIAQ
 |           |. |... | |.... |.  . . |.           .|. .|.  .  | |..  | . ||||||..||||       ..|||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

-FTNS------------------TDTKPAGTAMYMAPEVFGNSR------YNSSVDVFSFGMLLYEMSERHVAYNH-YSKEELNQLAQNR----------
 .|.|                    .  .||  .|||||  . .      |. ..|. |.| .. || . .. .   .  . . . ..|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---NVYPEFSSRTP-------------------IELQNLITRC
   .  | . ...                     |... | .|
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKC
Kinase 97119.m00144.AA ULK 29-262 20 1e-37 131.45 In-house 1-304 (324) Show / Hide 
Range on Protein: 29-262
Range on HMM: 1-304/324
Sequence Identity: 20% (62 aa)

FSFDYEIGAGGYG-VVHHGTDKVT---GKEVAIKQLKRERLKDALEQ--------KYVQEVFTTASCK---DRF--IVKLVGFTIEE---PYSIIAEFLP
.. . ..| | .| .|. |..| |   .. ||.|.  .  ...   .        .  .|. .    |     .  ||||  .. .     . || |. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

KGPLSKVLYHR-SHKERV-----LSPKQLTVIALGVATGLSHMRSIGLIHRDIKASNILLNEKNIPT------------IIDFGIAQFTNS-TDTKPA--
 | |.. .  .  ..| .     || ..   .    . |. .... . |||||| .|||...... |            | ||| |.. .. .  .    
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

---------GTAMYMAPEVFG----NSRYNSS-VDVFSFGMLLYEMSERHVAYNHYSKEELN----QLAQNR--------NVYPEFS---SRTPI--ELQ
         || .||||...     .  |... .|..|.|...|||    . .. . .....    .| .|.        |   .|    .  .|  |..
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

NLITRC
.|| |.
DLIRRM
Kinase 97119.m00144.AA LRRK 29-281 21 7e-37 127.99 In-house 1-351 (351) Show / Hide 
Range on Protein: 29-281
Range on HMM: 1-351/351
Sequence Identity: 21% (75 aa)

FSFDYEIGAGGYG-VVHHGTDK--------------------------VTGKEVAIKQLKRER------------------------------LKDALE-
. .  .|| ||.| .|. .. .                            ...||||...|..                              . |... 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

-QKYVQEVFTTASCKDRFIVKLVGFTIEEPYSIIAEFLPKGPLSKVLYHRSHKER-----VLSPKQLTVIALGVATGLSHMRSIG--LIHRDIKASNILL
 ... .||. . . .   ||.|.||.| .|. .. |..| | |...| .... ..     ..|.  .  ||| .| |. .. |    .|||| |  ||||
FREFRHEVWIMSHLNHPNIVSLKGFCI-HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

NEKNIP------------TIIDFGIAQ----FTNSTDTKPAGTAMYMAPEVFG---NSRYNSSVDVFSFGMLLYE-MSERHVAYNHYS---KEELNQLAQ
.. . .            .|.|||| .    |...   .  |.  .||||. .   .. |.  ||..||||.|.| .. .| .. ...   . ... . .
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE

N---RNVYPEFSSR-TPI-----ELQNLITRCW-GLPKDRPQPEEIYELFKT
.   .   | ...   |      ..|.||. || . ||.|| ...| .  ..
DKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 97119.m00144.AA ULK 29-262 19 3.4e-36 123.88 In-house 1-309 (329) Show / Hide 
Range on Protein: 29-262
Range on HMM: 1-309/329
Sequence Identity: 19% (61 aa)

FSFDYEIGAGGYGVVHHGTDKVT----GKEVAIKQLKRERLKDALEQ--------KYVQEVFTTASCK----DRF----IVKLVGFTIEE---PYSIIAE
.. . ..| | .|.|. |..| |    .. ||.|.. .. ..  . .           .|. .    |      .    ||||  .. .     . || |
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FLPKGPLSKVLYHR-SHKERV-----LSPKQLTVIALGVATGLSHMRSIGLIHRDIKASNILLNEKNIPT------------IIDFGIAQFTNST-----
. . | |.. .  .  . | .     || ..   .    . |. .... . |||||| .|||...... |            | ||| |.. ..      
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-DTKPA------GTAMYMAPEVFG----NSRYNSS-VDVFSFGMLLYEMSERHVAYNHYSKEELN-----QLAQNRNVYP--------EFS-----SRTP
  .         || .||||...     .  |... .|..|.|...|||    . .. . .....     .| .|... |        .|          
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

IELQNLITRC
 |...|| |.
PECKDLIRRM
Kinase 97119.m00144.AA MLK 29-279 26 6.3e-35 118.63 In-house 1-291 (291) Show / Hide 
Range on Protein: 29-279
Range on HMM: 1-291/291
Sequence Identity: 26% (77 aa)

FSFDYEIGAGGYGVVHHGTDKVTGKE-----VAIKQLKRERLKDALE----QKYVQEVFTTAS--CKDR---FIVKLVGFTIEEPYS--IIAEFLPKGPL
. |   ||.|..|.|. |  .  .|.     ||.|. . .   |. .    |. ... .  ..  ..      |....|  ...|.   |. |....|.|
IQFHEWIGSGSFGKVWKG--RWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSL

SKVLYH-RSHKE---------RVLSPKQLTVIALGVATGLSHMRSIG---LIHRDIKASNILLNE------KNIPTIIDFGIAQFTNST---DTKPAGTA
. ||.  ||. .         || .. ..  .|| .| |..   |     .||||.| .|||. |      . .  | |||.. . ...    .. |||.
YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTY

MYMAPEVF---GNSRYNSSVDVFSFGMLLYEMSERHVAYN-HYS-KEELNQLAQNRNVYPEFSSRTPIELQNLITRCWGL-PKDRPQPEEIYELF
 .|||||.    ...|. ..||.|.|..|.||  | | |  ||.  . . . |.|..  |  |.  |  . .|...||   |..||   .| . .
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPST-CPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 97119.m00144.AA Ciliate-E2-Unclassified 29-219 23 9e-35 118.04 In-house 1-263 (352) Show / Hide 
Range on Protein: 29-219
Range on HMM: 1-263/352
Sequence Identity: 23% (61 aa)

FSFDYEIGAGGYGVVHHGTDKVTGKEV-AIKQLKRERLKDALEQKYV-------QEVFTT----------------ASCKDRFIVKLV-GFTIEEPYSII
. . . || ||.|.|..  .| .. .. |.|..|  . .. . ....       .|..                   .... ||||..  |. ..   |.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

AEFLPKGPLSKVLYHRSH------------KERV-LSPKQLT-----VIALGVATGLSHMRSIG-LIHRDIKASNILLNEKN---IPTIIDFGIA----Q
 |... | |.. . .|..            |.|  .. .|        ..  .  ||... . .  |||||| .|||.....    . ||||||.    |
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

FTNSTDTKP---------------AGTAMYM----APEVFGNSRYNSS----VDVFSFGMLLYEM
. |.. |.                .|| .||    ||||...  |. |    .|..|.|..||||
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEM
Kinase 97119.m00144.AA TK 29-279 14 1.8e-32 105.55 In-house 1-486 (486) Show / Hide 
Range on Protein: 29-279
Range on HMM: 1-486/486
Sequence Identity: 14% (70 aa)

FSFDYEIGAGGYG---VVHHG------TDKVTG-------------------KEVAIKQLKRERLKDALEQKY-----------------VQEVFTTASC
  .  ..|.| .|   .|. |       .. ..                    .||.|.|| .   .. |..                  . ...  . .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

KDRFIVKLVG-FTIE------------EPYSIIAEFLPKGP----LSKVLYHRSHKERV-----------------------------------------
.   ||.|.|  | .            ||. |. |. |.|     | . |  ...|..                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSPKQLTVIALGVATGLSHMRSI------GLIHRDIKASNILLNEKNI-----------PTIIDFGIA-
                               |...||  ... .| |.... |       ...|||. | |.|..|.|.             | ||| . 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------QFTNSTDTKPAGTAMY-----------------------------MAPEVFG---------NSRYNSSVDVFSFGMLLYEMSE--RHVAYNHY
          .| |   . .  .                             ||||..          . .. .  ||.||| |..|.    .   |   
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SK---------EELNQLAQN--------------RNVYPEFSSRTP-------------IELQNLITRCWGL-PKDRPQPEEIYELF
|          .|. .. ..              |.  |     ..              |.. |...|| . |.|||  ....| .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 97119.m00144.AA Dicty4-Unclassified 29-279 28 2.8e-31 104.38 In-house 1-263 (263) Show / Hide 
Range on Protein: 29-279
Range on HMM: 1-263/263
Sequence Identity: 28% (76 aa)

FSFDYEIGAGGYGVVHHGTDKVTGKEVAIKQLKRERLKDA--LEQKYVQEVFTTASCKDRFIVKLVGFTIEEP------YSIIAEFLPKGPLSKVLY-HR
   | .|| |    || |  |  ||.||.| .   . |    . | .  ||    |      ||. |  |  |      . |. ||..|| |  |     
IQIDQFIGKGHFSKVHKGNWK--GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCI-NPRSHKSTMCIVMEFMHKGNLFEVIHSKP

SHKERVLSPKQ--LTVIALGVATGLSHMRSIGLIHRDIKASNILLNEKNIPTIIDFGIAQFT--NSTDTKPAGTAMYMAPEVFGNSRYNSSVDVFSFGML
| ... ..        .|. .| |. |. .  .||||||.||||.   .   | ||||.  .  | . |  |||    .||.     ||.  ||.|..|.
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMM

LYEMSERHVAYNHYS-KEELNQLAQNRNVYPEFSSRTPIELQNLITRCWG-LPKDRPQPEEIYELF
|||.      |       ..  .   .   |. ..  .  .. ||  ||   |. ||  ..| .  
LYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 97119.m00144.AA TyrKc 29-279 24 3e-29 104.42 SMART 1-280 (280) Show / Hide 
Range on Protein: 29-279
Range on HMM: 1-280/280
Sequence Identity: 24% (71 aa)

FSFDYEIGAGGYGVVHHGTDKVTGKEVAIKQLKRERLKDALEQKYVQEVFTTASC--KDRFIVKLVGFTIE--------EPYSIIAEFLPKGPLSKVL-Y
 ... ..| | .|.|..|| |    .||.| || .      ..   .|     .   .   ||.|.|  ..        ||. |. |. |.| | . | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

HRSHKERVLSPKQLTVIALGVATGLSHMRSIGLIHRDIKASNILLNEKNIPTIIDFGIAQFTNST-------DTKPAGT---AM------YMAPEVFGNS
|| .    |..|.|  ... .| | ..  | ..||||. | |.|..|...  | ||| . .  .        |.. . .   .        ||||..  .
HRPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

RYNSSVDVFSFGMLLYEMSERHVAYNHY------SKEELNQLAQNRNVYPEFSS-------RTPIELQNLITRCWGL-PKDRPQPEEIYELF
....  ||.||| ...|.  .             | .|. .. ....  |   .       . | |. .....||   |.|||  .||.|.|
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 97119.m00144.AA Pkinase_Tyr 88-219 30 3.3e-16 55.5 Pfam 66-207 (270) Show / Hide 
Range on Protein: 88-219
Range on HMM: 66-207/270
Sequence Identity: 30% (44 aa)

IVKLVGFTI--EEP--YSIIAEFLPKGPLSKVLYHRSHKERVLSPKQLTVIALGVATGLSHMRSIGLIHRDIKASNILLNEKNIPTIIDFGIAQFTNSTD
||.|.|  .  .||  . |. |. |.| | . |  ... .. |..|.|  ... .| |...  |...||||. | |.|..|.|.  | ||| |    ..|
IVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDD

TK-PAGT-----AMYMAPEVFGNSRYNSSVDVFSFGMLLYEM
.   ...        ||||.. ......  || ||| |..|.
YYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEI
Kinase 97119.m00144.AA Pkinase_Tyr 29-61 37 0.002762 11.75 Pfam 1-37 (270) Show / Hide 
Range on Protein: 29-61
Range on HMM: 1-37/270
Sequence Identity: 37% (14 aa)

FSFDYEIGAGGYGVVHHGTDK----VTGKEVAIKQLK
 .|. ..|.| .|.|..|| |     |. .||.| ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK
Kinase 97119.m00144.AA Pkinase_Tyr 251-279 40 0.025509 8.48 Pfam 241-270 (270) Show / Hide 
Range on Protein: 251-279
Range on HMM: 241-270/270
Sequence Identity: 40% (12 aa)

TPIELQNLITRCW-GLPKDRPQPEEIYELF
.| |. .|...||   |.|||  .||.| .
CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL