Gene 80596.m00217 (T.vaginalis)

80596.m00217

Species: T.vaginalis
Alias: 80596.m00217, TvagK0359
External Links:
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
80596.m00217.AA Protein None 725 None Fasta, JSON
80596.m00217.kin_dom Protein Kinase Domain None 250 None Fasta, JSON

Protein domain

Protein domains of 80596.m00217.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 80596.m00217.AA AGC 304-553 28 4.5e-140 364.63 In-house 1-395 (395) Show / Hide 
Range on Protein: 304-553
Range on HMM: 1-395/395
Sequence Identity: 28% (113 aa)

FSFKKQISRGAYARVFLAKKE------STGDVVAIKVISRKH---AAR---KNTAFTE------------KNILVKFQ----------SEHVVS-LYYTL
| |.| |..|.. .|.|..|       .||.. |.||.. ||     .      . ||            .|||.| .          .  .|. |.|. 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

CGVNN--LYIVMEYVP--------GGDLKTVLHHLG-----CMDEHNARYYIVQ-------IVAALQDLRK-HKIVHRD-LKPDNILIDRDGHLKLADFG
   ..  ||.||||.|        ||.. . ||  |     ..||  ||.|. .       || ||. | . ..|.||| |||.|||.|.|||.||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSFVGVV----------------------------------------------------EKTLEFAG--TPDYVAPEIVLNKGHSFPADYWS--LGVIIY
|. .|.                                                     ..|  | |  ||.|.||||.    .....|.||  ||...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELLTGVPPFHGKTPE----------ETFMNIC-------EGIFEP----------IDGSKEAIDLIRQLLRPNPNERLGCRS-------VSDIMEHPFF
|.||| |||.|..|.          |.| .|.       ...  |             |.|| |||..|| ..|..||||.        ...|..||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 80596.m00217.AA S_TKc 304-553 34 8.4e-98 332.13 SMART 1-231 (231) Show / Hide 
Range on Protein: 304-553
Range on HMM: 1-231/231
Sequence Identity: 34% (91 aa)

FSFKKQISRGAYARVFLAKKESTGDVVAIKVISRKHAARKNTAFTEKNILVKFQSEHVVSLYYTLCGVNNLYIVMEYVPG--GDLKTVLHHLGC------
. . ..| .||...|..... .|| .||||.|.       ...  | .|| | . ...| ||..    ..||.||||..|  |||...... |.      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

MDEHNARYYIVQIVAALQDLRKHKIVHRDLKPDNILIDRDGHLKLADFGLSFVGVVEKTLEFAGTPDYVAPEIVLNKGHSF-PADYWSLGVIIYELLTGV
..|  ||.|. ||. ||. . .|.|.||||||.|||.|.  |.|..||||. .        | |||.|.|||..   |... ..| ||.|.|.||.|.| 
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

PPFHGKTPEETFMNICEGIFEPIDGSKEAIDLIRQLLRPNPNERLGCRSVSD----IMEHPFF
|||.  .....| .|.         |.||.|.||..|. .|..|...  .      |. ||.|
PPFP--QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 80596.m00217.AA Akt 304-553 37 6.5e-83 264.87 In-house 1-264 (264) Show / Hide 
Range on Protein: 304-553
Range on HMM: 1-264/264
Sequence Identity: 37% (98 aa)

FSFKKQISRGAYARVFLAKKESTGDVV-AIKVISRKHAARKNT---AFTEKNILVKFQSEHVVSLYYTLCGVNNLYIVMEYVPGGDLKTVLHHLGCMDEH
| |.| . .|....|||.|| .|...  |.||.. ..   ||    ..||.|||.. ..  .|.|.|     ..||.||.|..||.| . |.. . ..| 
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

NARYYIVQIVAALQDLRKHKIVHRD-LKPDNILIDRDGHLKLADFGLSFVG-VVE--KTLEFAGTPDYVAPEIVLNKGHSFPADYWS-LGVIIYELLTGV
 ||.|. .|. |.. | .. |. || ||| |||.|.|||..|.||||.  . . .  ||  | ||| | |||| ...||. ..| |. ||...||...| 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFHGKTPEETFMNICEG-IFEP--IDGSKEAIDLIRQLLRPNPNERLG--CRSVSDIMEHPFF
|||. .  .. | .| .. .  |  .  |.|. |||..||  .|..|||     . .|..||.|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 80596.m00217.AA AktR 304-553 37 5.3e-82 278.74 In-house 1-268 (268) Show / Hide 
Range on Protein: 304-553
Range on HMM: 1-268/268
Sequence Identity: 37% (101 aa)

FSFKKQISRGAYARVFLAKKE-STGDVVAIKVISRKHAARKN---TAFTEKNILV-KFQSEHVVSLYYTLCGVNNLYIVMEYVPGGDLKTVLHHLGCMDE
| . | . .||...|.|..|   .....|.|.|. |.  ..|    . ||.||.  . .    | |.|.    ..|...|||.|||.| ..| . . ..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

HNARYYIVQIVAALQDLRKH-KIVHRDLKPDNILIDRDGHLKLADFGLSF---VG-VVEKTLEFAGTPDYVAPEIVLN-KGHSFPADYWSLGVIIYELLT
  || |..||. ||. | .| .|. |||||.|||.| |||.|..|||||    .    ||.  | ||| |.|||.... ||| ...|.|..|. |||..|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GVPPFHGKTPEETFMNICEGI-FEPIDG---SKEAIDLIR-QLLRPNPNERLG--CRSVSDIMEHPFF
| |||  |  .. | .| .   ... .    |... |||  .||  |||.|||  | . ..| .||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 80596.m00217.AA CAMK 309-553 20 5.5e-81 260.55 In-house 1-425 (425) Show / Hide 
Range on Protein: 309-553
Range on HMM: 1-425/425
Sequence Identity: 20% (89 aa)

QISRGAYARVFLAKKESTG------------DVVAIKVISRKHAAR----------------------------KNTAFTEKNILVKFQ-------SEHV
.. ||... |.|..  .|.              ||||.|..| .                              .   . | .|. | |        ...
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSLYYTLCG-------------------VNNLYIVM---EYVPGG----DLKTVLHHLGC---------------MDEHNARYYIVQIVAALQDLRKHKI
..|| .                       ...|.||   ||..||    ||   .   ||               ..|. ||.|. ||. |.. . .|.|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPDNILIDRD-----------------GHLKLADFGLS--FVGVV-----------------------EKTLEFAGTPDYVA-PEIVLN------
|||||||.|||.| .                 . .|..|||..  | .                         .|  .| ||| |.| ||...       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------KGHSFPADYWSLGVIIYELLTGVPPFHGK-------------TPEETFMNICEGIFEPIDGS-------------------------KEAID
        .......| ||.||| | .|.| ||| |.             ...|.| .|..| .. ..                           .|..|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIRQLLRPNPNERLGCRSVSDIMEHPFF
|||..|...|..|.   .......||..
LIRKMLQVDPEKRM---TIEQCLNHPWM
Kinase 80596.m00217.AA Pkinase 304-553 28 1.6e-80 278.61 Pfam 1-293 (293) Show / Hide 
Range on Protein: 304-553
Range on HMM: 1-293/293
Sequence Identity: 28% (84 aa)

FSFKKQISRGAYARVFLAKKESTGDVVAIKVISRKHAARKN--TAFT--EKNILVKFQSEHVVSLYYTLCGVNNLYIVMEYVPGG----DLKTVLH--HL
. ....| .|....|..... .||..||.|.|...|.  .   |..   |  |. .......| ||..    ...|.||||..||    ||.....    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GCM--DEHNARYYIVQIVAALQDLRKHKIVHRDLKPDNILIDRDGHL----KLADFGLSF---VGVVEKTLEFAGTPDYVAPEIVL-NKGHSFPADYWSL
||.  .|. .. |. ||. .|. . ...|.||||||.|||||..||.    |..||||.        . .  |.|||.|.|||... ..... ..| ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVIIYELLTGVPPFHGK------TPEETFMNICE-----GIFEPIDGS-----------------KEAIDLIRQLLRPNPNERLGCRSVSDIMEHPFF
|.|.||.|.| ||| |.      .. . . .| .      .......|                 .|..|.|. .|...|..|..     .|..||.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase 80596.m00217.AA RSK 307-553 37 1.9e-77 263.63 In-house 1-278 (278) Show / Hide 
Range on Protein: 307-553
Range on HMM: 1-278/278
Sequence Identity: 37% (104 aa)

KKQISRGAYARVFLAKKE---STGDVVAIKVISRKHAARKNT----AFTEKNILVKFQ-SEHVVSLYYTLCGVNNLYIVMEYVPGGDLKTVLH---HLGC
 |.  .|.|  ||| .|     || . | ||.... ......    ..|| |||   | .  .|.|.|.      ||..|||..||.| | |    |.||
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

MDEHNARYYIVQIVAALQDLRKHKIVHRDLKPDNILIDR---DGHLKLADFGLSFVGVVE---KTLEFAGTPDYVAPEIVL----NKGHSFPADYWSLGV
..|. |..|. .|| |.. | ...|.||||||.||| |    .||.|| |||..  .. .   .|  | .| .|.|||..     ..||.  .|.|||||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

IIYELLTGVPPFHG---KTPEETFMNICEGIFEPIDG-----SKEAIDLIRQLLRPNPNERLGC--RSVSDIMEHPFF
..||.||| |||.|   ....|.. .|..| | .  .     |.|| ||||..|  .|. ||||  . ...| .||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 80596.m00217.AA Ciliate-E2-Unclassified 304-553 23 6.7e-73 248.51 In-house 1-352 (352) Show / Hide 
Range on Protein: 304-553
Range on HMM: 1-352/352
Sequence Identity: 23% (83 aa)

FSFKKQISRGAYARVFLAKKESTGDVV-----AIKVISRK-HAARKN-------TAFTEKN-------------ILVKFQSEHVVSLYYTLCGVNNLYIV
. . ||| .|... |.........  .     ..|....| .  ...       ..  .|.             ||. ......| ..|.    .|.|||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYVPGGDLKTVLHHL-----------------GCMDEHNAR-----YYIVQIVAALQDLRKHK-IVHRDLKPDNILIDRDG---HLKLADFGLS-----
|||..||||.  . .                   . .| .|.     .|. ||. .|. | . . |.|||.||.|||.| .|   ..|..|||.|     
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

----FVGV---------VEKTLEFAGTPDYV----APEIVLNKGHS----FPADYWSLGVIIYELLTGVPPFHGKTPEE----------------TFMNI
      .           ...  |.||| |     |||.  .....    . .|.||||||.||.|.| .|| ... |.                 . ||
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

CEG-----IFEP----IDGSKEAIDLIRQLLRPNPNERLGCR-SVSDIMEHPFF
...      |..     . |.||.|.|..||. ... ... | . ..|..||.|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 80596.m00217.AA Ciliate-E2 304-553 22 2.5e-69 236.64 In-house 1-365 (365) Show / Hide 
Range on Protein: 304-553
Range on HMM: 1-365/365
Sequence Identity: 22% (84 aa)

FSFKKQISRGAYARVFLAKK-----------------------ESTGDVVAIKVIS---RKHAARKNTAF----------TEKNILVKFQSEHVVSLYYT
. | |.| .|... |...|.                       . ..  .|.|...    ..  ...  .           ||||| . .. ... .|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LC--GVNNLYIVMEYVPGGDLKTVLHHL-----------GCMDEHNARYYIVQIVA---------------ALQDLRKHK-IVHRDLKPDNILIDRDGHL
      ||.|.||||. ||||.  . .            ....|  ..|.. ||.                ||. | . . |.|||.||.|||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLADFGLS-FVGVV-------------------EKTLE-------------FAGTPDYVAPEIVLNKG---------HSFPADYWSLGVIIYELLTGVPP
|..||||| ..                      ..|               ..||| |.||||. .|.         ... .|.||||||.||.|.| ||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FHGKTPEETFMNICEGIFE-------------------PIDGSKEAIDLIRQ----LLRPNPNERLGCRSVSDIMEHPFF
|        . .|... ..                   . . |.|..|||..    .|  .|..|..  . ..|..||.|
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase 80596.m00217.AA MAST 304-454 46 5.9e-67 214.77 In-house 1-154 (334) Show / Hide 
Range on Protein: 304-454
Range on HMM: 1-154/334
Sequence Identity: 46% (71 aa)

FSFKKQISRGAYARVFLAKKESTGDVVAIKVISRKHAARK---NTAFTEKNILVKFQSEHVVSLYYTLCGVNNLYIVMEYVPGGDLKTVLHHLGCMDEHN
| |.| ||.||| .|.|.|. .|.| .|.|||     ..|   .. ..|.|||   |...||...|..   |.|..||||. |||... ||..|..||. 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ARYYIVQIVAALQDLRKHKIVHRDLKPDNILIDRDGHLKLADFGLSFVGVVEKT
|. || ..| .|. | .| ||||||||||.||| .|| ||.||||| || . ..
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDL
Kinase 80596.m00217.AA MAST 304-454 45 4.2e-65 197.58 In-house 1-157 (337) Show / Hide 
Range on Protein: 304-454
Range on HMM: 1-157/337
Sequence Identity: 45% (72 aa)

FSFKKQISRGAYARVFLAKKESTGDVVAIKVISRKHAARK---NTAFTEKNILVKFQSEHVVSLYYTLCG--VNNLYIVMEYVPGGDLKTVLHHLG-CMD
| |.| ||.||| .|.|.|. .|.| .|.|||     ..|   ...| |.|||.  | ..||...|.      . |..||||. |||  . |...| ||.
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EHNARYYIVQIVAALQDLRKHKIVHRDLKPDNILIDRDGHLKLADFGLSFVGVVEKT
|. |. || ..| .|  | .. ||||||||||.||| .||.||.||||| || . ||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKT
Kinase 80596.m00217.AA NDR 304-446 39 4.9e-53 161.58 In-house 1-151 (350) Show / Hide 
Range on Protein: 304-446
Range on HMM: 1-151/350
Sequence Identity: 39% (60 aa)

FSFKKQISRGAYARVFLAKKESTGDVVAIKVISRKHAARKNTAF---TEKNILVKFQ--SEHVVSLYYTLCGVNNLYIVMEYVPGGDLKT---VLHHLGC
| . |.|..||. .|.|..| .||...|.|..  .   .|| .    .|. |... .  .. ||.|||.    ..|| ||||.||||..|   .|  ...
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

MDEHNARYYIVQIVAALQDLRKHKIVHRDLKPDNILIDRDGHLKLADFGLS
 .|. || ||  .| |. .. |  ..|||.||||.|||.|||.|| ||||.
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLC
Kinase 80596.m00217.AA MAST 459-553 47 9.7e-52 155.99 In-house 230-337 (337) Show / Hide 
Range on Protein: 459-553
Range on HMM: 230-337/337
Sequence Identity: 47% (51 aa)

GTPDYVAPEIVLNKG-HSFPADYWSLGVIIYELLTGVPPFHGKTPEE-TFMNICE--GIFEPIDG---------SKEAIDLIRQLLRPNPNERLGCRSVS
||||| |||. | .| .. |.|.||.|.|.||.|.|.||| | |||| .| ||       | ...         |.||.|||..||.||| .||| . . 
GTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGAD

DIMEHPFF
.|..||||
EIKQHPFF
Kinase 80596.m00217.AA MAST 459-553 45 8.1e-46 145.48 In-house 226-334 (334) Show / Hide 
Range on Protein: 459-553
Range on HMM: 226-334/334
Sequence Identity: 45% (50 aa)

GTPDYVAPEIVLNKG-HSFPADYWSLGVIIYELLTGVPPFHGKTPEETFMNICEGI---FEPIDG---------SKEAIDLIRQLLRPNPNERLGCR-SV
||||| |||. |..| |. | |.||.|.|.||.|.|.||| ..||||.| ||        |  .|         |.||.|||..|| |.|..||| .  .
GTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNGA

SDIMEHPFF
 ....||||
DEVKQHPFF
Kinase 80596.m00217.AA NDR 459-553 44 3.7e-43 130.53 In-house 243-350 (350) Show / Hide 
Range on Protein: 459-553
Range on HMM: 243-350/350
Sequence Identity: 44% (48 aa)

GTPDYVAPEIVLN-KGHSFPADYWSLGVIIYELLTGVPPFHGKTPEETFMNI--CEGIF------EPIDG--SKEAIDLIRQLLRPNPNERLGCRS--VS
||||| |||.... .|...  |.||||.| ||.|.|.|||.. ||.||.|.|  .. ..       | .   |.|| ||||.|. |.|..|||     | 
GTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVD

DIMEHPFF
.|  ||||
EIKSHPFF
Kinase 80596.m00217.AA Pkinase_Tyr 304-446 25 4.9e-17 58.32 Pfam 1-158 (270) Show / Hide 
Range on Protein: 304-446
Range on HMM: 1-158/270
Sequence Identity: 25% (41 aa)

FSFKKQISRGAYARVFLAKKE----STGDVVAIKVISRKHAARKN---TAF-TEKNILVKF-QSEHVVSLYYTLC-GVNN--LYIVMEYVPGGDLKTVLH
 .| |.. .||. .|....      .|.  ||.|.. . .|  ..    .|  | .|. .. . ...|.||           .||||||.|.|||.. |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

H----LGCMDEHNARYYIVQIVAALQDLRKHKIVHRDLKPDNILIDRDGHLKLADFGLS
      .  . .    . .|| .... |  ....||||   |.|...... | .||||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 80596.m00217.AA TyrKc 304-548 20 9.6e-16 31.85 SMART 1-280 (280) Show / Hide 
Range on Protein: 304-548
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

FSFKKQISRGAYARVFLAKKESTGDVVAIKVISRKHAARKNTAFTEKNILVKF--QSEHVVSLYYTLCGV-------NNLYIVMEYVPGGDLKTVLHHLG
 ...|.. .||. .|....       ||.|..   .   .     | .|. |.  . ...| ||               |.|||||.|.||||  |.  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

C-MDEHNARYYIVQIVAALQDLRKHKIVHRDLKPDNILIDRDGHLKLADFGLSFVGVVE-------KTLEFAG--TPD------YVAPEIVLNKGHSFPA
         .. .|| .  . | .....||||   |.|...... | .|||||  .  .       ..   ..    .        |||    .  ..  
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DYWSLGVIIYELLT-GVPPFHG-----KTPEETFMNICEG-IFEPIDG---------SKEAIDLIRQLLRPNPNERLGCRSVSDIM
| || || ..|..| | .|  |     ....| . .. .|   .. .          ..|  ....|  . .|..|   . . ...
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 80596.m00217.AA S_TK_X 554-601 22 0.000292 12.6 SMART 1-79 (79) Show / Hide 
Range on Protein: 554-601
Range on HMM: 1-79/79
Sequence Identity: 22% (18 aa)

KGIDWTALDT----FEPPFCPCLK----SEEDTSYFG----NCSLKDYADIQ-------------------FDLESNRK
.|||| .|       |||| | .|    |..|||.|     ... ..  | .                   |   . . 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 80596.m00217.AA Pkinase_Tyr 481-512 37 0.86329 3.3 Pfam 198-232 (270) Show / Hide 
Range on Protein: 481-512
Range on HMM: 198-232/270
Sequence Identity: 37% (13 aa)

WSLGVIIYELLT-GVPP-FHGKTPEETFMNI-CEG
|| || ..|..| |  | . | ..|| .  |  .|
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG