87076.m00034

Species: T.vaginalis
Alias: TvagK0060, 87076.m00034
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
87076.m00034.AA Protein None 327 None Fasta, JSON
87076.m00034.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 87076.m00034.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 87076.m00034.AA CAMKL 13-265 31 3.9e-94 300.79 In-house 1-297 (297) Show / Hide
Range on Protein: 13-265
Range on HMM: 1-297/297
Sequence Identity: 31% (95 aa)

FSHFKKIGEGAFGKVFTALN-SKTNIQVAIKCVD--KINLMTEANRTVF----------QSELAIYNKIE---HPFLTQFYATTEDNAG------VYIAL
.   | .|.|.||||  |.. . |...|||| .|  ||.. . ...             . | .|  ..    ||   ..| . |.         .|. .
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFGEKGT--LLDRIVSQ----RKLKEQQSCKIFCEIVSALNYLHNTAKIIHRDIKAENIIVDNNDD--IRLIDFGLSSFMNT-----KEEMNERCGTFVY
|  . |   |.|.||..    ....| . ...|. ||||.||.|.   |.|||||.||| .|.|..  | .||||.| ..        . ....||.  |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

SSPEMLRG--IPYT-QSIDIWSCGILLYLMVTGTFPFASEDQR---------ELKQDICFKDPQIPTSISQDCRDLLLKLLTKEPSERITIEEIAVHPWI
 .||.. |   ||  . .||||||..|| ||.|..||  ..           ..|. .. . | |. ..| |||||. |.|.. |..|.||..|  ||| 
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM





Kinase 87076.m00034.AA CAMK 18-265 21 4.9e-93 300.08 In-house 1-425 (425) Show / Hide
Range on Protein: 18-265
Range on HMM: 1-425/425
Sequence Identity: 21% (93 aa)

KIGEGAFGKVFTALNSKTN------------IQVAIKCVDKINLM-------------------------TEANRTVFQSELAIYNK-------IEHPFL
..|.|.||||. . . .|.             .|||| .||  |                          .. .|  ...|..| .|       . || .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

TQFYATTED-----------NAG---------VYIAL---EFGEKG----TLLDRIVSQ---------------RKLKEQQSCKIFCEIVSALNYLHNTA
 ..| . ||           .           .|. .   |. . |     |.|.||..               ....|.. ...|  |.||..|.|.  
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

KIIHRDIKAENIIVDNND-----------------DIRLIDFGLSSFMNTKE------------------------EMNERCGTFVYSS-PEMLRG----
 |.|||.| ||| .|.|.                 .| .||||.. ... .|                         |...|||  | . ||.|.|    
-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

----------IPYTQSIDIWSCGILLYLMVTGTFPFASE-------------DQRELKQDICFKDPQ-IPTS-----------------------ISQDC
           .|....|.||||..|| |..|..|| ..             ...||.. |.  . . .|                         .||.|
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

RDLLLKLLTKEPSERITIEEIAVHPWI
.||. |.|...|..|.|||..  |||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 87076.m00034.AA MARK 13-265 38 1e-91 300.07 In-house 1-262 (262) Show / Hide
Range on Protein: 13-265
Range on HMM: 1-262/262
Sequence Identity: 38% (100 aa)

FSHFKKIGEGAFGKVFTALNSKTNIQVAIKCVDKINLMTEANRTVFQSELAIYNKIEHPFLTQFYATTE--DNAG-VYIALEFGEKGTLLDRIVSQ--RK
.   | ||.|...||  |.. .|...|||| ..| .|    ..  ...|..|  |..||  .... . |  ..   .|. .|  ..| |.|.|...  ..
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LKEQQSCKIFCEIVSALNYLHNTAKIIHRDIKAENIIVDNND--DIRLIDFGLSSFMNTKEEMNERCGTFVYSSPEMLRGIPYT-QSIDIWSCGILLYLM
|.|    .||  ||||.||.|.   |.|||||.||| .| |   .| .||||.|   .. .  |. |||  | .||.. . ||. . .||||.|..|| |
LHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

VTGTFPFA--SEDQRELKQDICFKDPQIPTSISQDCRDLLLKLLTKEPSERITIEEIAVHPWI
|.|.|||   . |. ||.. |   ...||. .| .||.|. .|||  |.||.|||||  |||.
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 87076.m00034.AA AGC 13-265 22 9.1e-90 231.55 In-house 1-395 (395) Show / Hide
Range on Protein: 13-265
Range on HMM: 1-395/395
Sequence Identity: 22% (91 aa)

FSHFKKIGEGAFGKVFTALNS------KTNIQVAIKCVD---KINL----MTEANRTV--------FQSELAIYNKIE----------HPFLTQ-FYATT
|   | ||.|.||||. .          |. . |.|...   || .    | | . |         ...|  |  |.           |||...  . . 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EDNAG--VYIALEF----------GEKGTLLDRIV---SQRKLKEQQSCKIFCE-------IVSALNYLHNTAKIIHRD-IKAENIIVDNNDDIRLIDFG
.|.    .|. .|.          |  . |. ..     .... |.... ...|       ||.|| |||.  .||||| .| |||  |..  |.| |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSSFMNTKE---------------------------------------------------EMNERCG--TFVYSSPEMLRGIPYTQSIDIWS--CGILLY
|.  .....                                                     .  ||  |  | .||.|    |... |.||   |.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

LMVTGTFPFASE----------DQRELKQDIC------FKDPQIP----------TSISQDCRDLLLKLLTKEPSERIT----------IEEIAVHPWI
 |.||  || ..          .. |. | |.      ......|           ..|....||. |||.|.|..|..          .|||  ||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase 87076.m00034.AA S_TKc 13-265 30 1e-84 288.66 SMART 1-231 (231) Show / Hide
Range on Protein: 13-265
Range on HMM: 1-231/231
Sequence Identity: 30% (81 aa)

FSHFKKIGEGAFGKVFTALNSKTNIQVAIKCVDKINLMTEANRTVFQSELAIYNKIEHPFLTQFYATTEDNAGVYIALEFGEK--GTLLDRIVSQRK---
.   .|||.||||||. . . ||. .||||...            ...|..|  |  ||.. ..| . .|   .|. .|. .   |.|.|.|.....   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LKEQQSCKIFCEIVSALNYLHNTAKIIHRDIKAENIIVDNNDDIRLIDFGLSSFMNTKEEMNERCGTFVYSSPEMLRGIPYTQ-SIDIWSCGILLYL
   . | . ......|..||.|.|.  .|||||.| ||| .|.   | ..||||. ..      .  |||  | .||.|   .|.  ..|.||||..|| 
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MVTGTFPFASEDQRELKQDICFKDPQIPTSISQDCRDLLLKLLTKEPSERITIEEIAV-------HPWI
|..|  ||   .. .. . |.          |....|.. |.|.|.|..|.|. |.         |||.
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 87076.m00034.AA Pkinase 13-265 29 5.1e-80 276.94 Pfam 1-293 (293) Show / Hide
Range on Protein: 13-265
Range on HMM: 1-293/293
Sequence Identity: 29% (86 aa)

FSHFKKIGEGAFGKVFTALNSKTNIQVAIKCVDKINLMTEANRTVFQ-SELAIYNKIEHPFLTQFYATTEDNAGVYIALEFGEKG----TLLDRIV--SQ
.   .|||.|.||.|. . . .|...||.|...| .   . ..| .  ||..| ... ||.  ..| . ||.  .|. .|. |.|     | |.|   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RKL--KEQQSCKIFCEIVSALNYLHNTAKIIHRDIKAENIIVDNNDDI----RLIDFGLSSF--MNTKEEMNERCGTFVYSSPEMLR-GIPYTQSIDIWS
...   |.. .... .|...|.|.|.  .|||||.| ||| .|||..|    ...||||. .     .. |. .|||  | .|| .| | .|....|.||
GCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

CGILLYLMVTGTFPFASE------DQRELKQDICFKDPQIPTSIS---------------------QDCRDLLLKLLTKEPSERITIEEIAVHPWI
||..|| |..| .|| ..      ||... . |  ...  . . .                     ..|.|.. ..|.| |..|.|.|.|  |||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 87076.m00034.AA AMPK 13-265 36 2.1e-76 226.38 In-house 1-254 (254) Show / Hide
Range on Protein: 13-265
Range on HMM: 1-254/254
Sequence Identity: 36% (92 aa)

FSHFKKIGEGAFGKVFTALNSKTNIQVAIKCVDKINLMTEANRTVFQSELAIYNKIEHPFLTQFYATT-EDNAGVYIALEFGEKGTLLDRIVSQRKLKEQ
.   |.||||.||||  .    |. .||||  .|  .  ..     |.|. |  .. || ..| |    | .   .. .|.   | | | ||. ..|.|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

QSCKIFCEIVSALNYLHNTAKIIHRDIKAENIIVDNNDDIRLIDFGLSSFMNTKEEMNERCGTFVYSSPEMLRGIPYT-QSIDIWSCGILLYLMVTGTFP
..|. |  |.|.. |.|.  .| ||| | ||.  | |  | . |||||  |.  |     ||   | .|||  | .|    .||||||. || |. |. |
EACRFFQQIISGVEYCHR-HMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

FASEDQRELKQDICFKDPQIPTSISQDCRDLLLKLLTKEPSERITIEEIAVHPWI
|  |....| . |.  ...||. .|....||. ..|.. | .||||..|  ||| 
FDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase 87076.m00034.AA Ciliate-E2-Unclassified 13-265 26 1.2e-73 251.04 In-house 1-352 (352) Show / Hide
Range on Protein: 13-265
Range on HMM: 1-352/352
Sequence Identity: 26% (95 aa)

FSHFKKIGEGAFGKVFTALNSKTNIQV-------AIKCVDKINLMTEANRTVFQSELAIYNK-----------------IEHPFLTQFYATTEDNAGVYI
.   |.||.|.||||. . ..|.. |.        |. ... . |..  . ... .    .|                 . |||.  .. . .|   .||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

ALEFGEKGTLLDRIVSQRK-----------------LKEQQSC-----KIFCEIVSALNYLHNTAKIIHRDIKAENIIVDNND---DIRLIDFGLSSFMN
 .|. | |.|.. | .. |                 . |||..     ..| .|...|.|||   .||||||| |||..|||     |..||||.|.. .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

T----------------KEEMNERCGTFVYS----SPEMLRGIPYTQS----IDIWSCGILLYLMVTGTFPFASEDQRE----------------LKQDI
.                ...|. .|||  |     .||.|.|  | .|    .||||.|..|| |..|..|| .... .                |.|.|
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

CFKDPQIPT--------SISQDCRDLLL----KLLTKEPSERITIEEIAVHPWI
. |..|.|          .|. . |..     |.| | |..|||.|.|  |||.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 87076.m00034.AA Ciliate-E2 13-265 25 2.8e-70 239.81 In-house 1-365 (365) Show / Hide
Range on Protein: 13-265
Range on HMM: 1-365/365
Sequence Identity: 25% (94 aa)

FSHFKKIGEGAFGKVFTALNSKTNIQVAIKCVDKIN-----------------LMTEANRTVFQ-SELAIYNKIE----------------HPFLTQFYA
.   ||||.|.||.|. . . |.. |.|||. |  .                  . . |   .. .|. |...|.                ||.. ..| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

TTE--DNAGVYIALEFGEKGTLLDRIVSQRKLK-----------EQQSCKIFCEIVS---------------ALNYLHNTAKIIHRDIKAENIIVDNNDD
. .  |.  .|. .|. . |.|.|.| ...| .           |.. ..|. .|..               ||.|||.  .||||||| |||..     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IRLIDFGLSSFMNTKEEMNE--------------------------------RCGTFVYSSPEMLRGIP---------YTQSIDIWSCGILLYLMVTGTF
| .|||||| . .......                                  |||  | .||.|.| .         |. ..||||.|..|| |..| .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFASEDQRELKQDICFKDPQ--------------IPTSISQDCRDLLLK----LLTKEPSERIT-IEEIAVHPWI
||    |.. ||  .  ...              .. ..||.| ||. |    .| |.|..||| .|.|  |||.
PF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 87076.m00034.AA AktR 13-265 32 1.6e-64 220.71 In-house 1-268 (268) Show / Hide
Range on Protein: 13-265
Range on HMM: 1-268/268
Sequence Identity: 32% (88 aa)

FSHFKKIGEGAFGKVFTALNS-KTNIQVAIKCVDKINLMTEANRTVFQSELAIYN-KIEHPFLTQFYATTEDNAGVYIALEFGEKGTLLDRIVSQRKLKE
|   | .|.||||||. .    ... |.|.| ..| ..  .  . . . |  |   .. |||. ... . ...   ....|. . | |.. . ...|..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

QQSCKIFCEIVSALNYLHNTAKIIHRDIKAENIIVDNNDDIRLIDFGLSS--FMNTKEEMNER-CGTFVYSSPEMLRG-IPYTQSIDIWSCGILLYLMVT
.|. ..|..|. || |||.. .|| ||.| |||  | .  ....|||||   ||. ..|..   |||..| .|||..   ... |.|.|. ||..| |||
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GTFPFASEDQRELKQDICFKD---PQIPTSISQDCRDLLL-KLLTKEPSERIT-----IEEIAVHPWI
|  || ...|... | | .|.   ...|. .|. |.||.  ||| | | .|..     .|||  ||| 
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF

Kinase 87076.m00034.AA STE 13-265 21 3.5e-62 212.9 In-house 1-359 (359) Show / Hide
Range on Protein: 13-265
Range on HMM: 1-359/359
Sequence Identity: 21% (80 aa)

FSHFKKIGEGAFGKVFTALNS------KTNIQ---------VAIKCVDKIN------------LMTE--ANRTVFQSELAIYNKIE--HPFLTQFYATTE
. . .|||.||||.|..|.|       ||. .         .||| ... |            |..    ..  .. |. | .|    ||.  ..| . .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DNA-------GVYIALEFGEKGTLLDRIV-SQRKLK-------------EQQSCKIFCEIVSA-LNYLHNTAKIIHRDIKAENIIVDNNDDIRLIDFGLS
..         ..|..|. . |.| | |     ..|             |.| ..| ..|. . |.|||.   |||||||. || .     . |.|||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-IIHRDIKPANILL-----VKLCDFGVC

SFMNT-----------------KEEMNERCGTFVYSSPEMLRG------IPYTQSIDIWSCGILLYLMVTGTFPFASEDQRELKQDIC------------
. ..                  ... |  .||  . .||....       .|. . |||| |...  |.||  |.. .   .    |             
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----FKDPQIPT-------------------SISQDCRDLLLKLLTKEPSERITIEEIAV--HPWI
    .. |..|.                   . |....| . | |.|.|..| | ..     ||.|
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase 87076.m00034.AA QIK 17-265 31 7.8e-61 208.42 In-house 5-272 (272) Show / Hide
Range on Protein: 17-265
Range on HMM: 5-272/272
Sequence Identity: 31% (86 aa)

KKIGEGAFGKVFTALNSKTNIQVAIKCVDKINLMTEANRTVFQSELAIYNKIEHPFLTQFYATTEDNAGVYIALEFGEKGTLLDRIVSQRK---------
. || | |. |  | .  |  .|||| .||   ..| | .    | .|   ..||. .  |   |     ||  |. . | . | .... .         
RTIGKGNFAVVKLARHRITKTKVAIKIIDK-SQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMVNSP

-----------LKEQQSCKIFCEIVSALNYLHNTAKIIHRDIKAENIIVDNNDDIRLIDFGLSSFMNTKEEMNERCGTFVYSSPEMLRGIPYT-QSIDIW
           ..|..  ..| .|.||  |.|.  .|.|||.|||||  ||| .| ..|||.| .  . . ..  ||.  |  |||. |. |.   .|||
DIGDQVLMGVPMAENEARRWFWQICSAVHYCHK-RNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVDIW

SCGILLYLMVTGTFPFASEDQRELKQDICFKDPQIPTSISQDCRDLLLKLLTKEPSERITIEEIAVHPWI
| |..|| .|.| .|| ..   .|.| .     .|| ..|||| .|  . |. .|. |.||. |  |.|.
SMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase 87076.m00034.AA TyrKc 13-265 22 1.1e-14 14.71 SMART 1-280 (280) Show / Hide
Range on Protein: 13-265
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

FSHFKKIGEGAFGKVFTALNSKTNIQVAIKCVDKINLMTEANRTVFQSELAIYNKI--EHPFLTQFYATTEDN-------AGVYIALEFGEKGTLLDRIV
 .  ||.||||||.|. .  .   ||||.|.. .        |  | .|. |  |.  .|| . ..|.   .          ..| .|. ..| |.|.. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SQRK-LKEQQSCKIFCEIVSALNYLHNTAKIIHRDIKAENIIVDNNDDIRLIDFGLSSFMNTK-------EEMNER---CGTFV----YSSPEMLRGIPY
. |. |. .. ...   | .  .|||   ..||||. | |. |..|  ..  ||||| .   .       .    .   .| ..      .|| ..   .
KHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TQSIDIWSCGILLYLMVTGTFPFASE------DQRELKQDI--CFKDPQIPT-------SISQDCRDLLLKLLTKEPSERITIEEIAVHPWI
|   |.|| |.... . |   .  ..      . .|. ...   .  || |          ...  .. ..    .|..| | .||  |  .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 87076.m00034.AA Pkinase_Tyr 17-159 28 2.1e-12 42.66 Pfam 5-158 (270) Show / Hide
Range on Protein: 17-159
Range on HMM: 5-158/270
Sequence Identity: 28% (45 aa)

KKIGEGAFGKVFTALNS----KTNIQVAIKCVDKINLMTEAN--RTVFQSELAIYNKI-EHPFLTQFYATTE-DNAG--VYIALEFGEKGTLLDRIVS--
||.||||||.|. .       .|.|.||.|.. |    .. .  |  | .|..|  ..  || . ..|.    .     .|| .|. ..| |||   .  
KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR

--QRKLKEQQSCKIFCEIVSALNYLHNTAKIIHRDIKAENIIVDNNDDIRLIDFGLS
  ...|. .. ...  .| ....||..  ..||||. | |. |..|  ..  ||||.
EDKQPLTMKDLLQMCWQIAKGMEYLES-KNCIHRDLAARNCLVTENNVVKICDFGLA