Gene 90428.m00036 (T.vaginalis)

90428.m00036

Species: T.vaginalis
Alias: TvagK0310, 90428.m00036
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
90428.m00036.AA Protein None 769 None Fasta, JSON
90428.m00036.kin_dom Protein Kinase Domain None 230 None Fasta, JSON

Protein domain

Protein domains of 90428.m00036.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90428.m00036.AA TKL-Unique 171-258 28 2.9e-25 86.15 In-house 192-290 (290) Show / Hide 
Range on Protein: 171-258
Range on HMM: 192-290/290
Sequence Identity: 28% (28 aa)

WSAPEIRSI--NDATTKSDVFLLGFILYELFTGDS------PFGNMSDDEIRQNIKD---KKRPSVSRLEPQNLSHLIQKCWSHQSENRPTIEEIVRTL
|.|||. .   .. ..||||.  |..|.|..|..       |. .|....... ...   ..|| ..   |.....|||.|| |....||. .||.  |
WMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 90428.m00036.AA LRRK 169-260 30 9.4e-25 84.49 In-house 243-351 (351) Show / Hide 
Range on Protein: 169-260
Range on HMM: 243-351/351
Sequence Identity: 30% (33 aa)

PPWSAPEIRSIN---DATTKSDVFLLGFILYELFTGD-SPFGNMS-------DDEIRQNIKDKKRPSVS---RLE---PQNLSHLIQKCWSHQSENRPTI
| | ||||.  |     |.|.|..  | ||.|| |..  ||....         .|...|... ||...   ...   .  .. |||.||.|. ..||. 
PGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHF

EEIVRTLES
..|| .|..
SQIVKRLSQ
Kinase 90428.m00036.AA TKL 169-258 21 1e-20 71.36 In-house 237-364 (364) Show / Hide 
Range on Protein: 169-258
Range on HMM: 237-364/364
Sequence Identity: 21% (28 aa)

PPWSAPEIRSIN----------------DATTKSDVFLLGFILYELFTGDSPFG-NMSDDEI---------RQNIKDKKRPSVS------------RLEP
| | |||.   .                ....|.||.  | .|.|..|.  |.  ......|          .......|| .                |
PRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCP

QNLSHLIQKCWSHQSENRPTIEEIVRTL
. .. |.|.||.|  |.||. .||. .|
PSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 90428.m00036.AA Dicty4 169-260 32 5e-19 60.26 In-house 181-277 (277) Show / Hide 
Range on Protein: 169-260
Range on HMM: 181-277/277
Sequence Identity: 32% (32 aa)

PPWSAPEIRSINDATTKSDVFLLGFILYELFTGDSPFG--NMSDDEIRQNIKD-KKRPSVSRLEPQNLSHLIQKCWSHQSENRPTIEEIVRT--LES
| | |||.   .  . |.||.  | .|.|..|.. |.    |. ....  . . | ||...   | ...||||.||.|  ..||. |||.    ||.
PCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 90428.m00036.AA TK-Unique 171-258 31 3.7e-17 55.81 In-house 202-294 (294) Show / Hide 
Range on Protein: 171-258
Range on HMM: 202-294/294
Sequence Identity: 31% (29 aa)

WSAPEIRS--INDA-TTKSDVFLLGFILYELFT-GDSPFGNMSDDEIRQNIKDKKRPSVSRLE-PQNLSHLIQKCWSHQSENRPTIEEIVRTL
| |||. .   . . ||||||  .| ...|.|| |  |...|....|...|.| .|. .     .. .  |.. ||..  | ||....|.  |
WMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase 90428.m00036.AA Dicty4-Unclassified 169-258 32 4.7e-17 54.91 In-house 172-263 (263) Show / Hide 
Range on Protein: 169-258
Range on HMM: 172-263/263
Sequence Identity: 32% (30 aa)

PPWSAPEIRSINDATTKSDVFLLGFILYELFTGDSPFGNMS-DDEIRQNIKDKK-RPSVSRLEPQNLSHLIQKCWSHQSENRPTIEEIVRTL
| | .||.      . ||||.  . .|||| ||| |.       ..   . ||| || ..   . ... ||  ||.     |||...|.  |
PKWESPECLMHESYNQKSDVYSYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 90428.m00036.AA Pkinase_Tyr 183-258 36 5.3e-15 51.44 Pfam 192-270 (270) Show / Hide 
Range on Protein: 183-258
Range on HMM: 192-270/270
Sequence Identity: 36% (29 aa)

TTKSDVFLLGFILYELFT-GDSP-FGNMSDDEIRQNI-KDKKRPSVSRLEPQNLSHLIQKCWSHQSENRPTIEEIVRTL
||||||   |  ..|.|| |..| . .||. |. . | .|  |    .. |. . .|...|| .. |.||| .||.. |
TTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 90428.m00036.AA RGC 171-260 23 6.7e-15 48.96 In-house 171-300 (300) Show / Hide 
Range on Protein: 171-260
Range on HMM: 171-300/300
Sequence Identity: 23% (31 aa)

WSAPEIRSINDA-------------TTKSDVFLLGFILYELFTGDS-----PFGN-------MSDDEIRQNIKDKK-------RPSVSRLE-------PQ
| |||.  ...              | | ||. .| |.||..|  .     ||.          ...|. ... .|       |||... |       ..
WTAPEHLREWRMPHQWGPHRQTQRGTQKGDVYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNP

NLSHLIQKCWSHQSENRPT-IEEIVRTLES
 | ||...||... |.||. .. |  .|..
CLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase 90428.m00036.AA RGC 171-260 23 8.1e-15 48.96 In-house 171-300 (300) Show / Hide 
Range on Protein: 171-260
Range on HMM: 171-300/300
Sequence Identity: 23% (31 aa)

WSAPEIRSINDA-------------TTKSDVFLLGFILYELFTGDS-----PFGN-------MSDDEIRQNIKDKK-------RPSVSRLE-------PQ
| |||.  ...              | | ||. .| |.||..|  .     ||.          ...|. ... .|       |||... |       ..
WTAPEHLREWRMPHQWGPHRQTQRGTQKGDVYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNP

NLSHLIQKCWSHQSENRPT-IEEIVRTLES
 | ||...||... |.||. .. |  .|..
CLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase 90428.m00036.AA TK 171-258 22 1.1e-14 44.86 In-house 351-486 (486) Show / Hide 
Range on Protein: 171-258
Range on HMM: 351-486/486
Sequence Identity: 22% (30 aa)

WSAPEIRS---------INDATTKSDVFLLGFILYELFT-G-DSPFGNMSD---------DEIRQNIKD--------------KKRPSVSRLEP------
| |||             .  ||||||. .|  ..|.|| |   . |.||.         .|. .....              . |.    . |      
WMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYR

--------QNLSHLIQKCWSHQSENRPTIEEIVRTL
        . .  |.|.||... | ||| ..... |
MHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 90428.m00036.AA Dicty5 171-262 32 4e-12 38.01 In-house 169-260 (260) Show / Hide 
Range on Protein: 171-262
Range on HMM: 169-260/260
Sequence Identity: 32% (30 aa)

WSAPEIRSINDATTKSDVFLLGFILYELFTGDSPFGNMSDDEIRQNIKDKKRPSVSRLEPQNLSHLIQKCWSHQSENRPTIEEIVRTLESGD
| |.|.   .  . | ||.  | .|.|.|| ..|. |.   .|   .    || .    |   | || |||     |||.  ||. ..||  
WMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 90428.m00036.AA Pkinase 169-258 20 2e-11 41.46 Pfam 175-293 (293) Show / Hide 
Range on Protein: 169-258
Range on HMM: 175-293/293
Sequence Identity: 20% (25 aa)

PPWSAPEIRS-INDATTKSDVFLLGFILYELFTGDSPFGNM----SDDEIRQNIKDKKRPSVSRLEP-----------------------QNLSHLIQKC
|.. |||.    .. ..|.|.. .| ||||...|  || .     . .. .| |. ...| ... .|                       ... ..| .|
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC

WSHQSENRPTIEEIVRT--L
.    . |||.|.|.    .
LCKDPKKRPTAEQILQHPWF
TyrKc 90428.m00036.AA TyrKc 22-258 19 1.8e-10 -53.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 22-258
Range on HMM: 1-280/280
Sequence Identity: 19% (62 aa)

ISLERDMFTCQQYTVSKAYSKTTGDRLIVLQPARKSFLSKPNNYTNFIIKCTK----------------L--TCPFLLPIVSY-TDE-------EPLMII
|.|..    ..  .| |.  |                       ..  .|. |                |    | .. .. . |..       |||||.
ITLGKKLGEGAFGEVYKGTWK-----------------------IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIV

SDYLKQGSLRDNLKTRNN-LSGAQKTIIAISIANAMLYCHH----------RNVFMPSLT-------------PDI-------IYITPRG--NAK--ISV
  | . |.|.| |. . . |. ...  ... ||. | | |.          ||.   .                |         |.....  ..|  . .
MEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI

IEMFQRPLPPWSAPEIRSINDA--TTKSDVFLLGFILYELFT-GDSPFGN-----MSDDEIRQNIKDKKRPSVSRL--------EPQNLSHLIQKCWSHQ
          | |||    |.   ||||||.  |  ..|.|| |..|  .     ||..|.....|. .|.              |. .  ....|| ..
R---------WMAPECI--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHED

SENRPTIEEIVRTL
 |.||| .||.. .
PEDRPTFSEIHECF
S_TKc 90428.m00036.AA S_TKc 29-265 17 1.6e-08 -51.82 SMART 1-231 (231) Show / Hide 
Range on Protein: 29-265
Range on HMM: 1-231/231
Sequence Identity: 17% (48 aa)

FTCQQY-------TVSKAYSKTTGDRLIV--LQPARKSFLSKPNNYTNFIIKCTKLTCPFLLPIVSYTDEEPLMIISDYLKQ--GSLRDNLKTRNN----
..  .        .| |.. | || .  .  .           ..  . |  . |  .|..  .  . ... | .. .|. .  |.|.| .| |.     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSGAQKTIIAISIANAMLYCHHRNV-----------FMPSLTPDIIYITPRGNAKISVIEMFQRPL---PPWSAPEIRSINDATT-KSDVFLLGFILY
  ..  .   ..  |..|. ||| ...           .        | |.  | |..       . .   | . |||.      .. |.|.  .| |||
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELFTGDSPFGNMSDDEIRQNIKDKKRPSVSRLEPQNLSHLIQKCWSHQSENRPTIEEIVR--TLESGDVVF
|...|  ||    .... ..|.           .. . ..|.||.    |.|||. |. .   .   .  |
EMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 90428.m00036.AA TK 87-132 12 5e-06 15.3 In-house 125-249 (486) Show / Hide 
Range on Protein: 87-132
Range on HMM: 125-249/486
Sequence Identity: 12% (16 aa)

TDEEPLMIISDYLKQGS----LRDNLKTRNN---------------------------------------------------------------------
...||.||.  | . |.    ||| |... .                                                                     
VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQW

-------LSGAQKTIIAISIANAMLY
       |. .|.  ..  ||..| |
CLTCKHQLTMHQLL-MCWQIACGMEY
Kinase 90428.m00036.AA TKL-Unique 92-159 24 3.9e-05 14.26 In-house 75-159 (290) Show / Hide 
Range on Protein: 92-159
Range on HMM: 75-159/290
Sequence Identity: 24% (21 aa)

LMIISDYLKQGSLRDNLK----------TRNNLSGAQKTIIAISIANAMLYCHHRN--VFMPSLTPDIIYITPR-----GNAKIS
. |...|.  |||.|.|             ..|. .|.  .|| || .| | ||..  .    |..  .... .      |.||.
MCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKIC
Kinase 90428.m00036.AA Dicty5 94-138 28 4.7e-05 13.35 In-house 76-125 (260) Show / Hide 
Range on Protein: 94-138
Range on HMM: 76-125/260
Sequence Identity: 28% (14 aa)

IISDYLKQGSLRDNLK-TRN----NLSGAQKTIIAISIANAMLYCHHRNV
... | ..|||.. |.  |.    ...  |.  .|| ||..| . |  |.
HVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMNI
Kinase 90428.m00036.AA TKL 69-132 23 0.001278 8.92 In-house 76-147 (364) Show / Hide 
Range on Protein: 69-132
Range on HMM: 76-147/364
Sequence Identity: 23% (18 aa)

IIKCTKLTCPFLLPIVSYTDEEP--------------LMIISDYLKQGSLRDNLKTRNNLSGAQKTIIAISIANAMLY
|  . .| .| ..... |  ..|              |.|. .| . |||...|         |.  .|..|| .| |
IMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNY
Kinase 90428.m00036.AA Pkinase_Tyr 87-132 26 0.018281 8.97 Pfam 74-126 (270) Show / Hide 
Range on Protein: 87-132
Range on HMM: 74-126/270
Sequence Identity: 26% (14 aa)

T-DEEP--LMIISDYLKQGSLRDNLKT----RNNLSGAQKTIIAISIANAMLY
| ..||  ..|.  | . |.|.| |..    ...|.  ..  ... ||..| |
TDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEY