Gene 92321.m00073 (T.vaginalis)

92321.m00073

Species: T.vaginalis
Alias: TvagK0416, 92321.m00073
External Links:
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
92321.m00073.AA Protein None 696 None Fasta, JSON
92321.m00073.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of 92321.m00073.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 92321.m00073.AA AGC 304-561 29 5.8e-149 388.15 In-house 1-395 (395) Show / Hide 
Range on Protein: 304-561
Range on HMM: 1-395/395
Sequence Identity: 29% (118 aa)

FTFIKRISSGAYAKVYLAEKN------STKDTYAIKVTPKSE---LRQKNEVRRVLTE------------KDILLKNS----------NPYIVE-IYYSI
| |.| |. |.. ||||..|.      .|.. ||.||  |..   ...||.|....||            ..|| | .          .|.||   .|| 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

IGKHN--LYLVMDFVP---------GG-DLYSLLQ---NIGTLDEDSSRIYIAQ-------IVQALDFLHG-KGILHRD-LKPDNILISCEGKLKLTDFG
  | .  ||.||...|         || .|.. ||   . |..||. .|.|.|.       || ||..||  .|| ||| |||.|||.  .| .||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSLYGAFDRGN--------------------------------------------------SEGLVG--TPGYMAPEIILSQPHNQCVDYWS--LGVILF
|.  |  |...                                                     ..|  || ||||||.    ... .|.||  ||....
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELLTGIPPFNRAT----------EQETFQAIVSG----KCDWSLL----------EDVSNDGIDFIRKLLTVDPSKRLGAN-------GISDIKNHSWF
|.|||.|||.  .          . |.|| | .|    ...  .           . .|..  |.|.|||..||.||||..       |...|||| ||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 92321.m00073.AA S_TKc 304-561 33 4.6e-98 333.0 SMART 1-231 (231) Show / Hide 
Range on Protein: 304-561
Range on HMM: 1-231/231
Sequence Identity: 33% (91 aa)

FTFIKRISSGAYAKVYLAEKNSTKDTYAIKVTPKSELRQKNEVRRVLTEKDILLKNSNPYIVEIYYSIIGKHNLYLVMDFVPG--GDLYSLLQNIGT---
..... | .||..|||.. ...|.  .|||. .          .... | .|| |   |.|| .|...   ..||.||....|  |||...... |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LDEDSSRIYIAQIVQALDFLHGKGILHRDLKPDNILISCEGKLKLTDFGLSLYGAFDRGNSEGLVGTPGYMAPEIILSQPHNQ-CVDYWSLGVILFE
   ..|   | |..||..||...| .||.||||||.|||..    .|..||||.            ..||| |||||..   ...   .| ||.|.||.|
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LLTGIPPFNRATEQETFQAIVSGKCDWSLLEDVSNDGIDFIRKLLTVDPSKRLGANGISD----IKNHSWF
.|.| |||   ..|..|. |.            | ...|||||.|..||.||..|  .      ||.| ||
MLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 92321.m00073.AA AktR 304-561 36 6e-94 318.41 In-house 1-268 (268) Show / Hide 
Range on Protein: 304-561
Range on HMM: 1-268/268
Sequence Identity: 36% (98 aa)

FTFIKRISSGAYAKVYLAEKN-STKDTYAIKVTPKSELRQKNEVRRVLTEKDILL-KNSNPYIVEIYYSIIGKHNLYLVMDFVPGGDLYSLLQNIGTLDE
|...| . .||..||||..|.  ... ||.|.  |......|  ....||..|.  ....| ||  .|..  | .|...|...|||.|.. |.......|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DSSRIYIAQIVQALDFLHGK-GILHRDLKPDNILISCEGKLKLTDFGLSL-YGAF-DRGNSEGLVGTPGYMAPEIILS-QPHNQCVDYWSLGVILFELLT
. .|.|.|||. ||..|| .  |  |||||.|||.  .| .|.||||||   .   ..     ..||| |||||.|.  ..||  ||.|..|. ..|..|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GIPPFNRATEQETFQAIVSGK-CDWSLLEDVSNDGIDFIR-KLLTVDPSKRLG--ANGISDIKNHSWF
|.|||.    .. || | .         ...|.   |.|  |||  .| ||||  .||...||.| ||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 92321.m00073.AA SGK 304-561 35 1.8e-92 285.87 In-house 1-283 (283) Show / Hide 
Range on Protein: 304-561
Range on HMM: 1-283/283
Sequence Identity: 35% (102 aa)

FTFIKRISSGAYAKVYLAEKNST------------------KDTYAIKVTPKSELR-------QKNEVRRVLTEK-DILLKNSNPYIVEIYYSIIGKHNL
| |.| |  | . |||.... ..                  .. ||.||  |   .       .|.|.. ...|. .|| . . | ||   |.   |  |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLVMDFVPGGDLYSLLQNIGTLDEDSSRIYIAQIVQALDFLHGKGILHRDLKPDNILISCEGKLKLTDFGLSLYGAFDRGNSEGLVGTPGYMAPEIILSQ
|.|||.| ||.. . ||  . . || .|.| |.|| ||. || . | .|||||.|||  ..| ..||||||.  |  .        ||| |.|||... |
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PHNQCVDYWSLGVILFELLTGIPPFNRATEQETFQAIVSGKCDWSLLEDVSNDGIDFIRKLLTVDPSKRLGAN-GISDIKNHSWF
||   || |.|| .|.|...|.|||     |. .. | ...    .   .|||  | |  ||. ||.||||.. .  .|||| .|
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPL--QIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 92321.m00073.AA Akt 304-561 38 4.3e-89 284.94 In-house 1-264 (264) Show / Hide 
Range on Protein: 304-561
Range on HMM: 1-264/264
Sequence Identity: 38% (102 aa)

FTFIKRISSGAYAKVYLAEKNSTKDTY-AIKVTPKSELRQKNEVRRVLTEKDILLKNSNPYIVEIYYSIIGKHNLYLVMDFVPGGDLYSLLQNIGTLDED
|.|.| . .|...||.|..|..|.. | |.||  |. . |||.|. ..||. || .  .|.||  .||   ...||.|||...||.|...||  .. .||
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

SSRIYIAQIVQALDFLHGKGILHRD-LKPDNILISCEGKLKLTDFGLSLYG---AFDRGNSEGLVGTPGYMAPEIILSQPHNQCVDYWS-LGVILFELLT
  | |.|.|. |...|| |.|  || ||| |||.. .| ..||||||.  .    .|. ..  . ||| |.||||.. . | ..|| |. ||....|...
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKT--FCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMC

GIPPFNRATEQETFQAIVSGKCDWSLLEDVSNDGIDFIRKLLTVDPSKRLG--ANGISDIKNHSWF
| |||     .. |. | ...      . .|..  |.|..||. ||.||||   |.. .||.| ||
GRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 92321.m00073.AA Ciliate-E2 304-561 26 4.9e-88 298.79 In-house 1-365 (365) Show / Hide 
Range on Protein: 304-561
Range on HMM: 1-365/365
Sequence Identity: 26% (99 aa)

FTFIKRISSGAYAKVYLAEKNST--------------------KDT---YAIKVTPKSELRQKNEVRRVL----------TEKDILLKNSNPYIVEIYYS
. ||| | .|....||.... ..                    |..   ||.|.  |....|.. . ...           || || ....|.|...|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

II--GKHNLYLVMDFVPGGDLYSLLQNI-----------GTLDEDSSRIYIAQIVQ---------------ALDFLHGKG-ILHRDLKPDNILISCEGKL
 .   ..|.||||... ||||.....|            . ..|   . ...||.|               || .|| |. |.|||.||.|||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGLSLYGAFDRGNSEG-------------------------------LVGTPGYMAPEIILSQP---------HNQCVDYWSLGVILFELLTGIPP
|..||||| .   |. |  .                               ..||||||||||. ...         ..  .|.|||||||.|.|.| ||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FNRATEQETFQAIVSGKCDWS----------------LLEDVSNDGIDFIRK----LLTVDPSKRLGANGISDIKNHSWF
|        .| |  .|.| .                  ...|....|.|.|    .| .||.||..  |...|.|| ||
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase 92321.m00073.AA RSK 307-561 37 5.9e-86 291.87 In-house 1-278 (278) Show / Hide 
Range on Protein: 307-561
Range on HMM: 1-278/278
Sequence Identity: 37% (103 aa)

IKRISSGAYAKVYLAEKN---STKDTYAIKVTPKSELRQKNE-VRRVLTEKDILLKNS-NPYIVEIYYSIIGKHNLYLVMDFVPGGDLYSLLQNIGT---
.|    |.| ||.|  |     |.  || ||  |....|..  .|...|| .||.     | ||. .|.   .  |||.|....||.|.  ||. ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LDEDSSRIYIAQIVQALDFLHGKGILHRDLKPDNILISC---EGKLKLTDFGLSLYGAFD-RGNSEGLVGTPGYMAPEIIL---SQP-HNQCVDYWSLGV
..||  ..|.|.|| |...|| .|| ||||||.|||      || .||||||.. ..  |  .     ..|  |||||..     |  |.. .|.|||||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

ILFELLTGIPPFNR---ATEQETFQAIVSGKCDWSLL--EDVSNDGIDFIRKLLTVDPSKRLG--ANGISDIKNHSWF
...|.||| |||     .. .|... | .|| . ..   . .|..  |.|||.|..||.||||   .....||.|.||
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 92321.m00073.AA Pkinase 304-561 28 6.4e-83 286.59 Pfam 1-293 (293) Show / Hide 
Range on Protein: 304-561
Range on HMM: 1-293/293
Sequence Identity: 28% (85 aa)

FTFIKRISSGAYAKVYLAEKNSTKDTYAIKVTPKSELRQKNEVRRVL-TEKDILLKNSNPYIVEIYYSIIGKHNLYLVMDFVPGG----DLYSLLQ--NI
......| ||....||.. . .| ...|.|. .|.. . . ...... .|  |... . |.||..|..   | ..|.||....||    ||.....  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GTL--DEDSSRIYIAQIVQALDFLHGKGILHRDLKPDNILISCEGKL----KLTDFGLS--LYGAFDRGNSEGLVGTPGYMAPEIIL-SQPHNQCVDYWS
|..  .|.  . |. ||...|...| .||.||||||.||||. .| .    |..||||.  ..     .   ...|||.|||||.|. .|.. . || ||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGVILFELLTGIPPFNRA------TEQETFQAIVSGKCDWSLLEDVS-------------------NDGIDFIRKLLTVDPSKRLGANGISDIKNHSWF
.|.||.|.|.| |||  .      .... .. | ... ...  .. |                    ...|||...|..||.||..   . .|..| ||
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase 92321.m00073.AA MAST 304-449 50 2.5e-71 229.11 In-house 1-146 (334) Show / Hide 
Range on Protein: 304-449
Range on HMM: 1-146/334
Sequence Identity: 50% (73 aa)

FTFIKRISSGAYAKVYLAEKNSTKDTYAIKVTPKSELRQKNEVRRVLTEKDILLKNSNPYIVEIYYSIIGKHNLYLVMDFVPGGDLYSLLQNIGTLDEDS
|.||| || ||| ||||.....|.|..|.||  ||..  || |  | .|..||   .||..|...||   | .|..||... |||. |||...|..||. 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

SRIYIAQIVQALDFLHGKGILHRDLKPDNILISCEGKLKLTDFGLS
 ..|||..| .|..|| .|| ||||||||.||. .|  ||||||||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase 92321.m00073.AA MAST 304-449 46 1.9e-69 211.08 In-house 1-149 (337) Show / Hide 
Range on Protein: 304-449
Range on HMM: 1-149/337
Sequence Identity: 46% (69 aa)

FTFIKRISSGAYAKVYLAEKNSTKDTYAIKVTPKSELRQKNEVRRVLTEKDILLKNSNPYIVEIYYSIIG--KHNLYLVMDFVPGGDLYSLLQNIG-TLD
| ||| || ||| .|||... .|.|..|.||  .. .  || |  |  |..||   .||..|...||     |  |..||... |||  |||...| ...
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EDSSRIYIAQIVQALDFLHGKGILHRDLKPDNILISCEGKLKLTDFGLS
|.  ..|||..| .|..|| .|| ||||||||.||   | .||||||||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase 92321.m00073.AA NDR 304-449 45 4.8e-67 205.58 In-house 1-151 (350) Show / Hide 
Range on Protein: 304-449
Range on HMM: 1-151/350
Sequence Identity: 45% (68 aa)

FTFIKRISSGAYAKVYLAEKNSTKDTYAIKVTPKSELRQKNEVRRVLTEKDILLKNS--NPYIVEIYYSIIGKHNLYLVMDFVPGGDLYS---LLQNIGT
|..|| |..||. .|.|. |..|.. ||.|.  |||  .||.|  |..|.||. . .  ||..|. ||| . | .|||||...||||. .   ||.. ..
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LDEDSSRIYIAQIVQALDFLHGKGILHRDLKPDNILISCEGKLKLTDFGLS
..||  | ||| .| |.. .|  |. |||.||||.||   | .|||||||.
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLC
Kinase 92321.m00073.AA MAST 463-561 43 1.4e-50 152.35 In-house 229-337 (337) Show / Hide 
Range on Protein: 463-561
Range on HMM: 229-337/337
Sequence Identity: 43% (47 aa)

VGTPGYMAPEIILSQP-HNQCVDYWSLGVILFELLTGIPPFNRATEQE-TFQAIVS--GKCDWSLL------EDVSNDGIDFIRKLLTVDPSKRLGANGI
.||| |.|||.|| |. ... ||.||.|.|..|.|.|.||||  | .| .|| |..   .  |         . .| . .| |.|||...|.||||||| 
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGA

SDIKNHSWF
 .||.|  |
DEIKQHPFF
Kinase 92321.m00073.AA MAST 460-561 43 1.4e-47 151.27 In-house 222-334 (334) Show / Hide 
Range on Protein: 460-561
Range on HMM: 222-334/334
Sequence Identity: 43% (49 aa)

EGLVGTPGYMAPEIILSQP-HNQCVDYWSLGVILFELLTGIPPFNRATEQETFQAIVSGKCD-WSLLED--------VSNDGIDFIRKLLTVDPSKRLGA
....|||.|.|||.|| |. |.. ||.||.|.|..|.|.|.||||  | .|.|| |.. .|   .. |.         | . .| |.|||..||.|||||
KQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGA

N-GISDIKNHSWF
| |  ..|.|  |
NNGADEVKQHPFF
Kinase 92321.m00073.AA PKA 304-447 38 1.8e-46 160.7 In-house 1-146 (263) Show / Hide 
Range on Protein: 304-447
Range on HMM: 1-146/263
Sequence Identity: 38% (56 aa)

FTFIKRISSGAYAKVYLAEKNSTKDTYAIKVTPKSELRQKNEVRRVLTEKDILLKNSNPYIV-EIYYSIIGKHNLYLVMDFVPGGDLYSLLQNIGTLDED
| .|. . .| ...|.|. . .... ||.|.  |.|  . . | .|..|| ||.  ..|.|| . |..     .||.||..||||.. | |.. | ....
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

SSRIYIA-QIVQALDFLHGKGILHRDLKPDNILISCEGKLKLTDFG
 ...|.| ||| ||..|| . | .||||| ||||  .| .|.||||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFG
Kinase 92321.m00073.AA NDR 462-561 40 2.7e-45 137.24 In-house 241-350 (350) Show / Hide 
Range on Protein: 462-561
Range on HMM: 241-350/350
Sequence Identity: 40% (45 aa)

LVGTPGYMAPEIILS-QPHNQCVDYWSLGVILFELLTGIPPFNRATEQETFQAIVSGKCDW-----SLLEDV--SNDGIDFIRKLLTVDPSKRLGANG--
.|||| |||||...  . .|| .|.||||.|..|.|.|.|||.  | |||.. | . |  |     .  ...  | .  | ||.|...||..|||..|  
TVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKG

ISDIKNHSWF
. .||.|..|
VDEIKSHPFF
Kinase 92321.m00073.AA PKA 464-561 43 1.3e-36 127.97 In-house 160-263 (263) Show / Hide 
Range on Protein: 464-561
Range on HMM: 160-263/263
Sequence Identity: 43% (46 aa)

GTPGYMAPEIILSQ-PHNQCVDYWSLGVILFELLTGIPPFNRA--TEQETFQAIVSGKCDW--SLLEDVSNDGIDFIRKLLTVDPSKRLG--ANGISDIK
||| |.|||||.|  .|.  || |.||.. .|.|.|.|||.    .  .... |..|| ..  ..  |. |   |.|.|||.||..||.|   ||. |||
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDA-NYFKDLIKKLLQVDLTKRYGNMKNGVNDIK

NHSWF
|| ||
NHKWF
Kinase 92321.m00073.AA TyrKc 304-561 23 1.3e-15 29.86 SMART 1-280 (280) Show / Hide 
Range on Protein: 304-561
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

FTFIKRISSGAYAKVYLAEKNSTKDTYAIKVTPKSELRQKNEVRRVLTEKDILLKN--SNPYIVEIYYSIIGK-------HNLYLVMDFVPGGDLYSLLQ
 |..| . .||. .||... .    . |.|.  ..       ..  . |  |. |   ..| || .|  .. .       . |..|| ..|.||| . |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NIGT-LDEDSSRIYIAQIVQALDFLHGKGILHRDLKPDNILISCEGKLKLTDFGLSLYGAFD--RGNSEGLV------GTPG-----YMAPEIILSQPHN
. .  |  .    .  || .  ..|| |.. ||||   |.|.. ..  | .||||| ..  |  .| |.         |. .      |||| |     .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

QCVDYWSLGVILFELLT-GIPPFNR-----ATEQETFQAIVSGKCDWSLLED-------VSNDGIDFIRKLLTVDPSKRLGANGISDIKNHSWF
   | || || ..|..| | .|         . || .. . .|.      .|        . .  . ...    ||..|   . |     |. |
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-----HECF
Kinase 92321.m00073.AA Pkinase_Tyr 304-449 26 4.1e-15 51.82 Pfam 1-158 (270) Show / Hide 
Range on Protein: 304-449
Range on HMM: 1-158/270
Sequence Identity: 26% (42 aa)

FTFIKRISSGAYAKVYLAEKN----STKDTYAIKVTPKSELRQKN-EVRRVLTEKDILLKN-SNPYIVEIYYSII-GKHN--LYLVMDFVPGGDLYSLLQ
 ||.| . .||. .||... .    .|| . |.|.  |    ...   .  . |  |. .  ..| ||  |  ..  .    .|.|| ..|.|||.. |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

N----IGTLDEDSSRIYIAQIVQALDFLHGKGILHRDLKPDNILISCEGKLKLTDFGLS
.     . |.      . .|| .....|. |.. ||||   |.|...... | .||||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 92321.m00073.AA S_TK_X 562-612 16 0.000181 14.51 SMART 1-79 (79) Show / Hide 
Range on Protein: 562-612
Range on HMM: 1-79/79
Sequence Identity: 16% (13 aa)

KSINWDKVE----ELPPPFVPKVT----R-NSTEYFEERYEF---LKSDVIE----------------KDIIEDIEDAR
..|.|||..    |..|||.||..        |..|.. ..      ... .                 |  ..    .
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 92321.m00073.AA APH 306-420 16 0.004851 11.25 Pfam 1-112 (248) Show / Hide 
Range on Protein: 306-420
Range on HMM: 1-112/248
Sequence Identity: 16% (21 aa)

FIKRISSGAYAKVYLAEKNSTKDTYAIKVTPKS----ELRQKNEVRRVLTEKDILLKNSNPYIVEIYY-----SIIGKHNLYLVMDFVPGGDLYSLLQNI
 ...||.|.   .|. . .   ..|  .. |..    ||..  .. |.| ...|      ... ....     . .|.  ....|...|| ||.      
WWRPISGGWSNRTYYRTTDD-RPRYVLRRYPPPWWAEELHREHRWLRHLAAHGIP-----VPVPRVLWGCTDDEFHGW--PWYLMEWLPGEDLWRW----

GT-LDEDSSRIYIAQIVQALDFLHG
 . |... .. ........|  ||.
-HALHCAQRPALLEALARFLARLHQ
Kinase 92321.m00073.AA APH 422-452 17 0.465333 4.49 Pfam 171-205 (248) Show / Hide 
Range on Protein: 422-452
Range on HMM: 171-205/248
Sequence Identity: 17% (6 aa)

GILHRDLKPDNILIS-CEGKLK---LTDFGLSLYG
...|.|..|.|....  ... .   . |.. . .|
CWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWG