Gene 94262.m00278 (T.vaginalis)

94262.m00278

Species: T.vaginalis
Alias: TvagK0428, 94262.m00278
External Links:
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
94262.m00278.AA Protein None 740 None Fasta, JSON
94262.m00278.kin_dom Protein Kinase Domain None 261 None Fasta, JSON

Protein domain

Protein domains of 94262.m00278.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94262.m00278.AA AGC 322-582 32 1.1e-153 400.65 In-house 1-395 (395) Show / Hide 
Range on Protein: 322-582
Range on HMM: 1-395/395
Sequence Identity: 32% (129 aa)

FTFIRKISSGAFAKVFLAIKT------RTGDIYAIKVTPKSS---LKQKNTFKRVLTE------------KDILLQNS----------NPFIVD-FYYSI
| |.. |. |.| ||.|. |        ||..||.||  |.    .|.||. ....||            ..|| . .          .||||   .|| 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

IGDHN--LYLVMEYLP---------GG-DLYSLLN---NIGSLDETAARIYTAQ-------IVKALEYLHS-HGIVHRD-LKPDNILINISGKLKLTDFG
  . .  ||.||||.|         || .|.. |    . |..|| .||.|.|.       || ||||||| .||.||| |||.|||..  | .||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSLYGAYDRAIP-----------------------------------------------DDSKTIVG--TPDYLAPEIILSSKHSFTADYWS--LGCVIY
|.  |  |. ..                                               |  .|..|  ||.|.||||.    .....|.||  |||..|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFLTGAPPFHMET----------EMETFAQILTGR---FDIDPL-----------EDMSDEVIDLIKHLLQVDPEKRLGFN-------GIKEIMDHPWF
|.||| |||. ..          .||.| .|. ||   ..  ..           . .|.|  ||||.||..||||||| .       |..||..||||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 94262.m00278.AA S_TKc 322-582 36 2.7e-107 363.69 SMART 1-231 (231) Show / Hide 
Range on Protein: 322-582
Range on HMM: 1-231/231
Sequence Identity: 36% (99 aa)

FTFIRKISSGAFAKVFLAIKTRTGDIYAIKVTPKSSLKQKNTFKRVLTEKDILLQNSNPFIVDFYYSIIGDHNLYLVMEYLPG--GDLYSLLNNIGS---
....||| .|||.||.......|| |.|||. .          .... | .|| .   |.|| .|...   ..||.||||..|  |||.... . |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LDETAARIYTAQIVKALEYLHSHGIVHRDLKPDNILINISGKLKLTDFGLSLYGAYDRAIPDDSKTIVGTPDYLAPEIILSSKHSF-TADYWSLGCV
   ..|  || |..||..||||.|||||.||||||.|||..    .|..||||.             .|..|||.|.|||..   ....  .| ||.||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

IYEFLTGAPPFHMETEMETFAQILTGRFDIDPLEDMSDEVIDLIKHLLQVDPEKRLGFNGIKE----IMDHPWF
.||.|.| |||.  .....| .|.            |.|..|.|...||.|||||..   . .    |. ||||
LYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94262.m00278.AA AktR 322-582 38 3.4e-97 329.22 In-house 1-268 (268) Show / Hide 
Range on Protein: 322-582
Range on HMM: 1-268/268
Sequence Identity: 38% (103 aa)

FTFIRKISSGAFAKVFLAIKT-RTGDIYAIKVTPKSSLKQKNTFKRVLTEKDILL-QNSNPFIVDFYYSIIGDHNLYLVMEYLPGGDLYSLLNNIGSLDE
|.... . .|||.||.|. |   ....||.|.  |. ....| .....||..|.  ....|||| ..|..  . .|...||| |||.|.. |.... ..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

TAARIYTAQIVKALEYLHSH-GIVHRDLKPDNILINISGKLKLTDFGLSL-YGAYDRAIPDDSKTIVGTPDYLAPEIILS-SKHSFTADYWSLGCVIYEF
  ||.| |||. ||||||.|  |. |||||.|||.   | .|.||||||   .  ..  . .|  ..||| |.|||.|.    | ...|.|..|..||| 
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYS--FCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEM

LTGAPPFHM--ETEMETFAQILTGRFDIDPLEDMSDEVIDLIK-HLLQVDPEKRLG--FNGIKEIMDHPWF
.|| |||     ..|  . .| .  . ... .. |..  |||.  ||. .|.||||   ||..|| .||||
VTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 94262.m00278.AA Akt 322-582 41 6.2e-93 297.41 In-house 1-264 (264) Show / Hide 
Range on Protein: 322-582
Range on HMM: 1-264/264
Sequence Identity: 41% (111 aa)

FTFIRKISSGAFAKVFLAIKTRTGDIY-AIKVTPKSSLKQKNTFKRVLTEKDILLQNSNPFIVDFYYSIIGDHNLYLVMEYLPGGDLYSLLNNIGSLDET
|.|.. . .|.|.||||. |  |...| |.||  |. . ||| .. ..||. ||    .||||  .||    ..||.||.| .||.|...|   .  .| 
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

AARIYTAQIVKALEYLHSHGIVHRD-LKPDNILINISGKLKLTDFGLSLYG--AY-DRAIPDDSKTIVGTPDYLAPEIILSSKHSFTADYWS-LGCVIYE
 || | |.|. |.|.|||..|. || ||| |||.   | ..||||||.  .   . |..     ||. ||| ||||||..   |. ..| |. ||||.||
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKT-----KTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYE

FLTGAPPFHMETEMETFAQILTGRFDIDPLEDMSDEVIDLIKHLLQVDPEKRLG--FNGIKEIMDHPWF
...|.|||. .   . | .|...   . . .  |.|  |||. ||. ||.||||  .|...||..||||
MMCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 94262.m00278.AA Ciliate-E2 322-582 27 1.7e-92 313.57 In-house 1-365 (365) Show / Hide 
Range on Protein: 322-582
Range on HMM: 1-365/365
Sequence Identity: 27% (105 aa)

FTFIRKISSGAFAKVFLAIKTRTGD-----------------------IYAIKVTPKSSLKQKNTFKRVL----------TEKDILLQNSNPFIVDFYYS
. ||.|| .|.|..|... . ...                        |||.|.  |. ..|..  ....           || || |...|.|. .|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

II--GDHNLYLVMEYLPGGDLYSLLNNI-----------GSLDETAARIYTAQIVK---------------ALEYLHSHG-IVHRDLKPDNILINISGKL
 .   |.|.||||||. ||||.....|            ....|  .. ...||..               ||||||| . |.|||.||.|||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGLSLYGAYD----------RAIPDDS-------------------KTIVGTPDYLAPEIILSSK---------HSFTADYWSLGCVIYEFLTGAP
|..||||| .   |            ... .                   .||.||| |.||||. . |         ... .|.||||...||.|.| |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFHMETEMETFAQILTGRFDID----------------PLEDMSDEVIDLIKH----LLQVDPEKRLGFNGIKEIMDHPWF
||        . ||. . .|..                  .. |.|..||||     .||.|||||..  |...|..||||
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase 94262.m00278.AA RSK 325-582 37 3.6e-92 312.53 In-house 1-278 (278) Show / Hide 
Range on Protein: 325-582
Range on HMM: 1-278/278
Sequence Identity: 37% (105 aa)

IRKISSGAFAKVFLAIKT---RTGDIYAIKVTPKSSLKQKNT-FKRVLTEKDILLQNS-NPFIVDFYYSIIGDHNLYLVMEYLPGGDLYSLLNNIGS---
..    |.. ||||  |.    || ||| ||  |. ..|...  ....|| .||.     ||||. .|.   .  |||.|||..||.|.  | . ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LDETAARIYTAQIVKALEYLHSHGIVHRDLKPDNILINI---SGKLKLTDFGLSLYGAYDRAIPDDSK---TIVGTPDYLAPEIIL---SSK-HSFTADY
..|. |..| |.||.|.|.||..||.||||||.||| .    .| .||||||.. ..      .|...   | ..| .|.|||..      . |.  .|.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-----RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDW

WSLGCVIYEFLTGAPPFHM---ETEMETFAQILTGRFDIDPL--EDMSDEVIDLIKHLLQVDPEKRLG--FNGIKEIMDHPWF
||||...|| |||.|||..   ..  |....|..|.|. .    . .|.|  |||...|..||.||||   ....|| .||||
WSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 94262.m00278.AA Pkinase 322-582 31 2e-86 298.22 Pfam 1-293 (293) Show / Hide 
Range on Protein: 322-582
Range on HMM: 1-293/293
Sequence Identity: 31% (96 aa)

FTFIRKISSGAFAKVFLAIKTRTGDIYAIKVTPKSSLKQKNTFKRVL-TEKDILLQNSNPFIVDFYYSIIGDHNLYLVMEYLPGG----DLYSLLN--NI
....||| ||.|..|.....  ||.|.|.|. .|.. | .    ... .|  |..  . |.|| .|..   . ..|.||||..||    ||....   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GSL--DETAARIYTAQIVKALEYLHSHGIVHRDLKPDNILINISGKL----KLTDFGLS--LYGAYDRAIPDDSKTIVGTPDYLAPEIIL-SSKHSFTAD
|..  .|  .. |  ||...|||.||.||.||||||.||||.  | .    |..||||.  ..           .|..|||.|.|||.|. .....  .|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

YWSLGCVIYEFLTGAPPFHME------TEMETFAQILTGRFDIDPLED-------------------MSDEVIDLIKHLLQVDPEKRLGFNGIKEIMDHP
 ||.||..||.|.| |||  .      ..|. ...|. .... |  ..                   .|.| .|.|| .|..||.||..   ...|. ||
MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHP

WF
||
WF
Kinase 94262.m00278.AA Ciliate-E2-Unclassified 322-582 24 1.4e-83 284.01 In-house 1-352 (352) Show / Hide 
Range on Protein: 322-582
Range on HMM: 1-352/352
Sequence Identity: 24% (88 aa)

FTFIRKISSGAFAKVFLAIKTRTGDIYAIKVTPKSSLKQKNTFKRV---------LTEKD-------------ILLQNSNPFIVDFYYSIIGDHNLYLVM
...|..| .|.|.||.....  .. .||.|   |.  . ..  ...         . .|              |||.. .|||| ..|    . |.|.||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYLPGGDLYSLLNNIGS-----------------LDETAAR-----IYTAQIVKALEYLHSHG-IVHRDLKPDNILINISG---KLKLTDFGLSLYGAYD
||..||||   ... ..                 ..| .|.      |.|||...|||||. . |.|||.||.|||.. .|   ..|..|||.| .  ..
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

------------RAIPDDSKTIVGTPDYL----APEIILSSKHS----FTADYWSLGCVIYEFLTGAPPFHMETEME----------------TFAQILT
            . ... ..|..||| |.    |||.. . ...    . .|.||||...||.|.| .||  ... .                 . .|. 
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

GRFDIDPLE------DMSDEVIDLIK----HLLQVDPEKRLGFNGIKEIMDHPWF
. ..... .      . |.|..|.|.     .|...|.||.   ....|. ||||
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI---TFEQILNHPWF
Kinase 94262.m00278.AA PKA 322-582 41 2.4e-83 283.18 In-house 1-263 (263) Show / Hide 
Range on Protein: 322-582
Range on HMM: 1-263/263
Sequence Identity: 41% (113 aa)

FTFIRKISSGAFAKVFLAIKTRTGDIYAIKVTPKSSLKQKNTFKRVLTEKDILLQNSNPFIVD-FYYSIIGDHNLYLVMEYLPGGDLYSLLNNIGSLDET
| .|. . .| |..| |. .  .|..||.|.  |.  .. .   .|..|| ||.. ..||||   |..   | .||.|||| |||.. | | . |.... 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

AARIYTA-QIVKALEYLHSHGIVHRDLKPDNILINISGKLKLTDFGLSLYGAYDRAIPDDSKTIVGTPDYLAPEIILSS-KHSFTADYWSLGCVIYEFLT
 |..| | ||| |||||||. |..||||| ||||.  | .|.|||| .        . | ..|. |||.|||||||.|.  |    | |.||..|||.|.
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFA------KKVDDRTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLA

GAPPFHME--TEMETFAQILTGRFDIDPLEDMSDE--VIDLIKHLLQVDPEKRLG--FNGIKEIMDHPWF
| |||  .  . |...  |. |. .  | .. ||.  . ||||.|||||..||.|   ||.  | .|.||
GYPPFYDHNRDPMQIYEKICNGKIKF-PRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 94262.m00278.AA MAST 322-467 47 1.6e-74 226.92 In-house 1-149 (337) Show / Hide 
Range on Protein: 322-467
Range on HMM: 1-149/337
Sequence Identity: 47% (71 aa)

FTFIRKISSGAFAKVFLAIKTRTGDIYAIKVTPKSSLKQKNTFKRVLTEKDILLQNSNPFIVDFYYSIIG--DHNLYLVMEYLPGGDLYSLLNNIG-SLD
| ||. || ||. .|.|... .|.|..|.||  .. .  ||  . |  |..|| . .|||.| ..||     .  |..||||. |||  |||...| ...
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

ETAARIYTAQIVKALEYLHSHGIVHRDLKPDNILINISGKLKLTDFGLS
|  |..|.|..| .||||||.|||||||||||.||   | .||||||||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase 94262.m00278.AA MAST 322-467 52 2.5e-74 238.96 In-house 1-146 (334) Show / Hide 
Range on Protein: 322-467
Range on HMM: 1-146/334
Sequence Identity: 52% (76 aa)

FTFIRKISSGAFAKVFLAIKTRTGDIYAIKVTPKSSLKQKNTFKRVLTEKDILLQNSNPFIVDFYYSIIGDHNLYLVMEYLPGGDLYSLLNNIGSLDETA
|.||. || ||. ||.|... .|.|..|.||  || .  ||  . | .|..|| . .|||.| ..||   . .|..||||. |||. |||...|..||  
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ARIYTAQIVKALEYLHSHGIVHRDLKPDNILINISGKLKLTDFGLS
|..|.|..| .||||||||||||||||||.||  .|  ||||||||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase 94262.m00278.AA NDR 322-467 45 1.1e-65 201.32 In-house 1-151 (350) Show / Hide 
Range on Protein: 322-467
Range on HMM: 1-151/350
Sequence Identity: 45% (69 aa)

FTFIRKISSGAFAKVFLAIKTRTGDIYAIKVTPKSSLKQKNTFKRVLTEKDILLQNS--NPFIVDFYYSIIGDHNLYLVMEYLPGGDLYS---LLNNIGS
|..|. |..||| .|.|. |  ||.|||.|.  ||   .||  . |..|.||. . .  ||..|  ||| . . .|||||||.||||. .   ||.. . 
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LDETAARIYTAQIVKALEYLHSHGIVHRDLKPDNILINISGKLKLTDFGLS
..| .|| | | .| |.|..|. |..|||.||||.||.  | .|||||||.
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLC
Kinase 94262.m00278.AA MAST 481-582 45 2.8e-45 135.86 In-house 226-337 (337) Show / Hide 
Range on Protein: 481-582
Range on HMM: 226-337/337
Sequence Identity: 45% (51 aa)

KTIVGTPDYLAPEIILSSK-HSFTADYWSLGCVIYEFLTGAPPFHMETEME-TFAQILTGRFDIDPLED--------MSDEVIDLIKHLLQVDPEKRLGF
| ..|||||.|||.||    .. ..|.||.| ..||||.| |||  .|  | .|..|.    .|   |.        ||.| .|||| |||..| ||||.
KQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGA

NGIKEIMDHPWF
|| .||. || |
NGADEIKQHPFF
Kinase 94262.m00278.AA MAST 481-582 45 3.1e-43 137.01 In-house 222-334 (334) Show / Hide 
Range on Protein: 481-582
Range on HMM: 222-334/334
Sequence Identity: 45% (51 aa)

KTIVGTPDYLAPEIILSSK-HSFTADYWSLGCVIYEFLTGAPPFHMETEMETFAQILTGR---FDIDPL------EDMSDEVIDLIKHLLQVDPEKRLGF
| ..|||||.|||.||    |. . |.||.| ..||||.| |||  .|  |.|..||  .     . .       | || |..|||. |||.||.||||.
KQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGA

N-GIKEIMDHPWF
| | .|.. || |
NNGADEVKQHPFF
Kinase 94262.m00278.AA NDR 483-582 40 4.1e-41 124.11 In-house 241-350 (350) Show / Hide 
Range on Protein: 483-582
Range on HMM: 241-350/350
Sequence Identity: 40% (45 aa)

IVGTPDYLAPEIILSSK-HSFTADYWSLGCVIYEFLTGAPPFHMETEMETFAQILTGR--F-----DIDPLEDMSDEVIDLIKHLLQVDPEKRLG-FN-G
.||||||.|||...  . ...| |.|||||. ||.|.| |||. .|  ||.  |.  .  .     .. | . .|.|  |||. |. .||..||| .. |
TVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKG

IKEIMDHPWF
. || .||.|
VDEIKSHPFF
Kinase 94262.m00278.AA TyrKc 322-577 23 4.8e-23 83.81 SMART 1-280 (280) Show / Hide 
Range on Protein: 322-577
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

FTFIRKISSGAFAKVFLAIKTRTGDIYAIKVTPKSSLKQKNTFKRVLTEKDILLQN--SNPFIVDFYYSIIGD-------HNLYLVMEYLPGGDLYSLL-
 |...|. .||| .|.... .      |.|.  ...       .  . |  |. .   ..| || .|  .. .       . |..|||| |.||| . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NNIGSLDETAARIYTAQIVKALEYLHSHGIVHRDLKPDNILINISGKLKLTDFGLSLYGAYDRAIPDD------SKTIV-----GTPD-----YLAPEII
.. . |       .  || .  |||||....||||   |.|..  .  | .|||||      |.| ||      .....     |. .      .||| |
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLS------RDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

LSSKHSFTADYWSLGCVIYEFLTGAPPFHME-----TEMETFAQILTGRFDIDPLED--------MSDEVIDLIKHLLQVDPEKRLGFNGIKEIM
  .| ..  | || | ...| .|   . . .      . .   . .  ..  .. ..        ..||. ...|   . |||.|  |. |.|..
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 94262.m00278.AA Pkinase_Tyr 322-467 29 7.9e-19 64.4 Pfam 1-158 (270) Show / Hide 
Range on Protein: 322-467
Range on HMM: 1-158/270
Sequence Identity: 29% (47 aa)

FTFIRKISSGAFAKVFLAIKT----RTGDIYAIKVTPKSSLKQKN-TFKRVLTEKDILLQN-SNPFIVDFYYSII-GDHN--LYLVMEYLPGGDLYSLLN
 ||..|. .||| .|.... .     |.   |.|.  | .  ...   .  . |  |. |  ..| || .|  ..  .    .|.|||| |.|||.. | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

N----IGSLDETAARIYTAQIVKALEYLHSHGIVHRDLKPDNILINISGKLKLTDFGLS
.     ..|.      . .|| |..|||.|....||||   |.|.. ... | .||||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 94262.m00278.AA Pkinase_Tyr 490-577 31 0.006868 10.41 Pfam 181-270 (270) Show / Hide 
Range on Protein: 490-577
Range on HMM: 181-270/270
Sequence Identity: 31% (28 aa)

LAPEIILSSKHSFTADYWSLGCVIYEFLT-GAPP-FHMETEMETFAQILTGRFDIDPLEDMSDEVIDLIKHLLQVDPEKRLGFNGIKEIM
.||| |  .| .   | || | ...| .| |. | .   .  | ...|   .   .. |. .||. ||.|.  . |||.|  |  | |..
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL