Gene 86824.m00119 (T.vaginalis)
86824.m00119
Species: T.vaginalis
Alias: 86824.m00119, TvagK0292
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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86824.m00119.AA | Protein | None | 768 | None | Fasta, JSON |
86824.m00119.kin_dom | Protein Kinase Domain | None | 250 | None | Fasta, JSON |
Protein domains of 86824.m00119.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 86824.m00119.AA | TKL | 220-460 | 27 | 8.7e-82 | 278.02 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 220-460 Range on HMM: 1-364/364 Sequence Identity: 27% (100 aa) IGTGTFGSVHIGTMNATN--------RKVAVKVLNTQ--ILGGR----------------------QLETFKREVW-TMATLNHPSILRLVGVTLTPP-- || |.|| |. |. . .. . ||||..... . . ... |..|.. | |.|| |....|. . || IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG ------------FCIVTELL-KGSLYDRLKFLSPTKRSIIALKVAQGMEQLHAAR--------IIHRDLKSANILLDEDDM--------------PRVCD .|||.|. .|||...| . .| .|| .|.||. ||. . ||||||||.|||.||. . .|| CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICD FGLVGFKTGA---------------------TRTGYVGTAQWMAPEVLRSSPF---------------YDEKVDVYSFGVLLWEMLTLHEPYSGMKQEQI ||| |... |. .|| .|||||||| ... |.||.||||||..|||.|| .||.... ... FGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPM V---------MGVIESGLRPLIP---------QNFSHS--KLVQLIERCWSEQPSMRPPFSTIATLL . |.|.. ||||.|| .. .. . .|...||.. |. || |..| | IFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | 86824.m00119.AA | MLK | 214-460 | 34 | 1.8e-73 | 250.41 | In-house | 1-291 (291) | Show / Hide |
Range on Protein: 214-460 Range on HMM: 1-291/291 Sequence Identity: 34% (100 aa) FTIGNTIGTGTFGSVHIGTMNATN---RKVAVKVLNTQI----LGG---RQLETFKREVWTMATLN-HPSILRLVGVTLTP-P-FCIVTELL-KGSLYDR ... || |.||.|. |.. ... . |||| .. | . ...|.. |... . .| ||.| ...|| | | . ||||.| . .||||. IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV LKF-----------------LSPTKRSIIALKVAQGMEQLHA-AR--IIHRDLKSANILLDE------DDMPRVCDFGLVGFKTGA-T-RTGYVGTAQWM |. .. .|| .|.||. ||. |. |||||||| |||.|| .. ..||||.. ... | ... ||. || LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM APEVL---RSSPFYDEKVDVYSFGVLLWEMLTLHEPYS-GMKQEQIVMGVIESGLRPLIPQNFSHSKLVQLIERCWSEQPSMRPPFSTIATLL ||||. |... |.||.||.|.||.|||||| .||. .... .| ..|.. |||| ||...... . .|...||.. |. || |. | . | APEVIQQFRCEK-YSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEH-WKKLMKQCWNQDPHKRPSFRQIVQHL |
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Kinase | 86824.m00119.AA | LRRK | 214-462 | 29 | 1.1e-70 | 241.19 | In-house | 1-351 (351) | Show / Hide |
Range on Protein: 214-462 Range on HMM: 1-351/351 Sequence Identity: 29% (105 aa) FTIGNTIGTGTFG-SVHIGTMN--------------------------ATNRKVAVKVLNT--------------------------------QILGGRQ . |.. || |.|| .|. .... . .||.|..|. . | LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA LETFKREVWTMATLNHPSILRLVGVTLTPPFCIVTELL-KGSLYDRLK------F------LSPTKRSIIALKVAQGMEQLHAAR--IIHRDLKSANILL . .| .||| | .||||.|. |.|... |.|.|.|.. |.||..|. | .|.. . ||| .| ||| || .. |||||||| |||| FREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL DEDDMP------------RVCDFGLVG--FKTGAT-RTGYVGTAQWMAPEVLRSS--PFYDEKVDVYSFGVLLWEMLTLH-EPYSGMK-------QEQIV . ... ..|||. . . .. . . |.||. .|||||..| |.||||.||||..||| ||. |. ... .||| WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE MGVIESGLRPLIPQNFSHS-----KLVQLIERCWSEQPSMRPPFSTIATLLMQ | .|||| |||.. . . .||. ||...| || ||.| | | -DKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ |
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Kinase | 86824.m00119.AA | Dicty4 | 214-462 | 38 | 2.4e-70 | 233.83 | In-house | 1-277 (277) | Show / Hide |
Range on Protein: 214-462 Range on HMM: 1-277/277 Sequence Identity: 38% (107 aa) FTIGNTIGTGTFGSVHIGTMNATNRKVAVKVL-NTQI-LGGRQLETFKREVWTMATLNHPSILRLVGVTL----TP-PFCIVTELL-KGSLYDRLKF--- .|.. ||.| ||.|. || . .||||.| |... . |. |..|| |. . || |. . | . .| .|||||.. ||.|| | INIEQRIGKGSFGEVYKGTWRGK--EVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS -------LS-PTKRS--IIALKVAQGMEQLHA--ARIIHRDLKSANILLDEDDMPRVCDFGLVG-FKTGA--TR--TGYVGTAQWMAPEVLRSSPFYDEK |. |. .. .|. .|.|| ||. .||||||||.|.| |.. |||||| .|.. . .. .||. ||||||... | |.|| EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP-YNEK VDVYSFGVLLWEMLTLHEPYS--GMKQEQIVMGVIESGLRPLIPQNFSHSKLVQLIERCWSEQPSMRPPFSTIATL--LMQ .|||||| .|||.|| |||. .| .|.| .| . .||| ||.... | . .||..||.. |. || |. | | ADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPS-WKHLIQWCWDHDPQHRPSFEEIIQRRILEH |
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Kinase | 86824.m00119.AA | TKL-Unique | 216-460 | 34 | 5e-67 | 229.0 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 216-460 Range on HMM: 1-290/290 Sequence Identity: 34% (102 aa) IGNTIGTGTFGSVHIGTMNATNRKVAVKVLNT-QILGGRQLETFKREVWTMATLN-HPSILRLVGVTL----TPP-FCIVTE-LLKGSLYDRLK------ ..|.||.|..|.| |. . . .||.|... . . ...|..|| .| .|. || |....|.. .|| .|||.| . ||||| | FWNKIGEGGYGQVYKGKWRGY--PVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN -------FLSPTKRSIIALKVAQGMEQLHAAR--IIHRDLKSANILLDED-----DMPRVCDFGLVGFKTGATRTGYV-----------GTAQWMAPEVL |.. .| .|...||||. || |||||||| |.|.|.. ..|||||. |.. ... . |...||||||| NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL RSS-PFYDEKVDVYSFGVLLWEMLTLHE------PYSGMKQEQIVMGVIE--SGLRPLIPQNFSHSKLVQLIERCWSEQPSMRPPFSTIATLL |.. |.||.||||||. |||..| . ||.|| |||. | . ..|| ||.. . ||..|| .|| || |..| . | RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHC-PKEYRDLIQQCWHHDPSQRPSFDEIIHRL |
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Kinase | 86824.m00119.AA | S_TKc | 214-466 | 27 | 3.5e-61 | 210.51 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 214-466 Range on HMM: 1-231/231 Sequence Identity: 27% (73 aa) FTIGNTIGTGTFGSVHIGTMNATNRKVAVKVLNTQILGGRQLETFKREVWTMATLNHPSILRLVGVTLTPPFCIVTELLKG---SLYDRLKF-------- ..|...|| |.||.|. .. . |.|.||.|... |...||. . .|| | .| .| . ...|.|.. | .|.|..| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF -LSPTKRSIIALKVAQGMEQLHAARIIHRDLKSANILLDEDDMPRVCDFGLVGFKTGATRTGYVGTAQWMAPEVLRSSPFYDE-KVDVYSFGVLLWEMLT ... .. .....| .| .||||||| .|||||| .||||| . | ..|| .|||||| |. |.|..|.|..|.|||. PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLC LHEPYSGMKQEQIVMGVIESGLRPLIPQNFSHSKLVQLIERCWSEQPSMRPPFSTIAT---LLMQADFH |.. |.| .. .| . . ..|..|. |. || . . . .. . GYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 86824.m00119.AA | TK | 214-460 | 17 | 3.6e-56 | 186.45 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 214-460 Range on HMM: 1-486/486 Sequence Identity: 17% (87 aa) FTIGNTIGTGTFG---SVHIGTMNATN-------------------------RKVAVKVLN--TQILGGRQLETFKR----------EVWTMATLN---- |.|...| | || |. |... | .||||.| . .... . . |. |. .. ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG -HPSILRLVG-VTLT------------PPFCIVTELLK-GS----LYDRLK------------------------------------------------- || |.||.| .| .|..||.|. . |. | | |. HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY ------------------------------FLSPTKRSIIALKVAQGMEQLHAA------RIIHRDLKSANILLDEDDM-----------PRVCDFGLV- .|.. . ... .|.||| ||. ...|||| |.|..|.. ...|||| DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR -----GFKTGATRTGYVGTAQ------------------------------WMAPEVLRSSPF--------YDEKVDVYSFGVLLWEMLTLH-EPYSGMK . .. |. . . |||||.|.. | . .| ||.|||||.||..|. ||| |. QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM QE---------QIVMGVIESG--------------LRPLIPQNFSH-------------SKLVQLIERCWSEQPSMRPPFSTIATLL | || ...| .|. |.. . . .|. .||...|. || ||.. | SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | 86824.m00119.AA | Pkinase | 214-451 | 27 | 2.1e-55 | 195.18 | Pfam | 1-282 (293) | Show / Hide |
Range on Protein: 214-451 Range on HMM: 1-282/293 Sequence Identity: 27% (79 aa) FTIGNTIGTGTFGSVHIGTMNATNRKVAVKVLNTQILGGRQLETFKR--EVWTMATLNHPSILRLVGVTLTPP-FCIVTELLKG-----SLYDRLK---- ..|| .|| |.||.| ... |...||||... . ...| | |. |. |||| |.|| .. ... ..|.|.. | .|.|... YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH -FL--SPTKRSIIALKVAQGMEQLHAARIIHRDLKSANILLDEDDMP----RVCDFGLVG---FKTGATRTGYVGTAQWMAPEVLRSSPFYDEKVDVYSF . |. ... ...|.| .|. .|||||||..|||.|... . ..||||| . |...|| .|||||.|... |. |||..|. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVLLWEMLTLHEPYSGM---KQEQIVMGVIESGLR-PLIPQNFSH---------------------SKLVQLIERCWSEQPSMRP |..|.|||. . |..| . | .|. .. || . . . . ..|..|. |. || GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP |
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Kinase | 86824.m00119.AA | TyrKc | 214-460 | 31 | 4.7e-55 | 190.13 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 214-460 Range on HMM: 1-280/280 Sequence Identity: 31% (90 aa) FTIGNTIGTGTFGSVHIGTMNATNRKVAVKVLNTQILGGRQLETFKREVWTMATL--NHPSILRLVGVTLT--------PPFCIVTELLK-GSLYDRL-- | | ..| | || |. ||.. ..||||.|. .| | || | | .|| |.||.|| .. .| .||.|. . |.| |.| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK --KFLSPTKRSIIALKVAQGMEQLHAARIIHRDLKSANILLDEDDMPRVCDFGLVGFKTGA----TRTGYVGT-----AQ------WMAPEVLRSSPFYD . |.. . ... .|.||| || ..||||| |.|..|. ...|||| . . .. | . . |||||.. . HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT EKVDVYSFGVLLWEMLTL-HEPYSGM----KQEQIVMGVIESGLRPLIPQNF-------SHSKLVQLIERCWSEQPSMRPPFSTIATLL .| ||.||||..||..|. .||.|| . | |. ...| |. .|.| .... |....|| |.|..|| ||.| .. TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | 86824.m00119.AA | DRK | 214-462 | 39 | 4.4e-52 | 174.69 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 214-462 Range on HMM: 1-258/258 Sequence Identity: 39% (104 aa) FTIGNTIGTGTFGSVHIGTMNATNRKVAVKVLNTQILG-GRQLETFKREVWTMATLNHPSILRLVGVTLTPP-FCIVTELL-KGSLYDRLK----FLSPT ||| || | .| | || | .|||| | | |.||. | | || | | . || ||..| . .|||| | .. IKIGNRIGRGNYGEVFRGTWRGT--QVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWP KRSIIALKVAQGMEQLHAAR--IIHRDLKSANILLDEDDMPRVCDFGLVG-FKT----GATRTGYVGTAQWMAPEVLRSSPFYDEKVDVYSFGVLLWEML . ... .| || || |||||||| | | || | |||| || ....| .|| | ||||||. . | || |||||.. |||.. LMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMT-MCGTPCWTAPEVLRNQR-YTEKADVYSFAIVLWECV TLHEPYSGMKQEQIVMGVIESGLRPLIPQNFSHSKLVQLIERCWSEQPSMRPPFSTIATLLMQ | || || |.|. | |.|| .||. . | .||. .||.| |. || . . | TRQDPYFGMPTFQVVFSVGRHGMRPPMPQWCP-PKYIQLMNDCWNEDPQHRPSMQECLERLEA |
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Kinase | 86824.m00119.AA | Dicty4-Unclassified | 214-460 | 31 | 2.3e-47 | 160.27 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 214-460 Range on HMM: 1-263/263 Sequence Identity: 31% (85 aa) FTIGNTIGTGTFGSVHIGTMNATNRKVAVKVLNTQILGGR--QLETFKREVWTMATLNHPSILRLVGVTLTP-----PFCIVTELL-KGSLYDRLK-FLS | || | | || | | . |||| .| | .. ||.|| . . || ... | . | .|||.|.. || | | IQIDQFIGKGHFSKVHKG--NWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPS PTKRSI---------IALKVAQGMEQLHAARIIHRDLKSANILLDEDDMPRVCDFGLVGFKTGATRTGYVG-TAQWMAPEVLRSSPFYDEKVDVYSFGVL ...| .|. .|||| || .||||.||.|||.| . .. |||. .. | | .||.|. | | ||||.... EQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHES-YNQKSDVYSYAMM LWEMLTLHEPYSGMK-QEQIVMGVIESGLRPLIPQNFSHSKLVQLIERCWSEQPSMRPPFSTIATLL |.|..| ||| . . | . .||| || | . .|| ||.. | || . | | LYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNC-DNFWKKLIKWCWHNDPNKRPTMNQIIQYL |
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Kinase | 86824.m00119.AA | TK-Unique | 214-460 | 27 | 4e-46 | 157.05 | In-house | 1-294 (294) | Show / Hide |
Range on Protein: 214-460 Range on HMM: 1-294/294 Sequence Identity: 27% (81 aa) FTIGNTIGTGTFGSVHIGTMNATN-----RKVAVKVLNTQILGGRQLETFKREVWTMATLN-HPSILRLVGVTLTP--PFCIVTELLKGS---------- ...|..||.| || |. |.. .. .|... ... . . . |..| | | || |....|.. .. |..|. | . .. LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR -L-------------------YDRLKFLSPTKRSIIALKVAQGMEQLHA--ARIIHRDLKSANILLDEDDMPRVCDFGLV------GFKTGATRTGYVGT ..|. ..|| .| .|.||| |. .|.|||| . |.|| || . .||||. | .. | . PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI AQWMAPEVLR--SSPFYDEKVDVYSFGVLLWEMLTL-HEPYSGMKQEQIVMGVIESGLRPLIPQNFSHSKLVQLIERCWSEQPSMRPPFSTIATLL . |||||.|. ... .| ||.|||||.||..|| ||.||.... .| |. | |.. |.. . . .|...||.. |..|| |..|. | R-WMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKD-IMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL |
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Kinase | 86824.m00119.AA | Shk | 318-456 | 41 | 3.3e-39 | 136.59 | In-house | 113-258 (269) | Show / Hide |
Range on Protein: 318-456 Range on HMM: 113-258/269 Sequence Identity: 41% (62 aa) GMEQLHA--ARIIHRDLKSANILLDEDDMPRVCDFGLVG-FKTGA----TRTGYVGTAQWMAPEVLRSSPFYDEKVDVYSFGVLLWEMLTLHEPYS-GMK || ||. .|||||||.|| | |.. |||||. |.. | ||. ||||||. |. .||.|||||| .|||.|| |||. . GMNWLHGSNCNIIHRDLKTANLLVDQNWRVKVCDFGFSQYMKKHEMLKDKQKGAKGTPLWMAPEVMMNHPY-NEKADVYSFGIILWEILTCQEPYPKHHS Q-EQIVMGVIESGLRPLIPQNFSHSKLVQLIERCWSEQPSMRPPFSTI .. . .. . .|| || . | | .||..|| |. || |. | EYDKFYEAICNKKERPPIPDDCPKS-LKHLIQKCWDHNPQRRPSFNEI |
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Kinase | 86824.m00119.AA | Pkinase_Tyr | 214-352 | 34 | 1.1e-29 | 101.1 | Pfam | 1-157 (270) | Show / Hide |
Range on Protein: 214-352 Range on HMM: 1-157/270 Sequence Identity: 34% (55 aa) FTIGNTIGTGTFGSVHIGTMN----ATNRKVAVKVLNTQILGGRQ--LETFKREVWTMATL-NHPSILRLVGVTL--TPP--FCIVTELLKG-SLYDRLK |.| ..| | ||.|. ||.. |. .||||.| . .| .| | ||. .| .| .|| |.||.|| . | .||.|. .. .|.| |. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR F-------LSPTKRSIIALKVAQGMEQLHAARIIHRDLKSANILLDEDDMPRVCDFGL |.. ... .|.||| |.. ..||||| |.|..|. ..||||| KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL |
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Kinase | 86824.m00119.AA | Pkinase_Tyr | 370-460 | 40 | 1.6e-23 | 80.33 | Pfam | 180-270 (270) | Show / Hide |
Range on Protein: 370-460 Range on HMM: 180-270/270 Sequence Identity: 40% (38 aa) WMAPEVLRSSPFYDEKVDVYSFGVLLWEMLTLH-EP-YSGMKQEQIVMGVI-ESGLRPLIPQNFSHSKLVQLIERCWSEQPSMRPPFSTIATLL |||||... . . .| ||.|||||.||..|. .| | ||. |. |. | |.| | .|.| . .. .|. .|| ..|..|| || | | WMAPECINYGK-FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEE-VYEYIYEDGYRMPCPEN-CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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Kinase | 86824.m00119.AA | Shk | 214-296 | 33 | 4.2e-07 | 21.87 | In-house | 1-84 (269) | Show / Hide |
Range on Protein: 214-296 Range on HMM: 1-84/269 Sequence Identity: 33% (29 aa) FTIGNTIGTGTFGSVHIGTMNATNRKVAVKVLNTQILGGRQLETFKREVWTMATLNHPSILRLVGV-T-LTPPFCIVTELL-KGSL . .|.| ||.| |. ..|||||. | . . |. || |. . || |. | | ||||| ||.| INREDFLGQGSFGKVYKGRCRG--KEVAVKVMHKQNFDENTMTSFRKEVHIMSKIFHPNICLFMGACTSQPGKCMIVTELMPKGNL |