Gene 81877.m00054 (T.vaginalis)

81877.m00054

Species: T.vaginalis
Alias: 81877.m00054, TvagK0367
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
81877.m00054.AA Protein None 452 None Fasta, JSON
81877.m00054.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of 81877.m00054.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 81877.m00054.AA PH 1-96 31 1.6e-21 78.75 SMART 1-82 (82) Show / Hide 
Range on Protein: 1-96
Range on HMM: 1-82/82
Sequence Identity: 31% (30 aa)

MIKAGWGTKQGGLIKTWKKRWFVLEKDALVYFTKEGGEEQGRIPIGSTCVVSPAPDCKKQPAFKIVTSERTYFIVTDTQKECSDWISAISNTIAHC
.|| || .|..    .||||||||  | |.|. ..  . .|.||. .  |.  .       .|.|.. .|||.. .....|. .|..|| . |...
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK--KPKGSIPLSDCTVRE-P-------CFEIHH-DRTYYFQCESEEEMQEWMQAIQKAIHNN
PH 81877.m00054.AA PH 1-94 36 6.8e-20 74.37 Pfam 1-92 (92) Show / Hide 
Range on Protein: 1-94
Range on HMM: 1-92/92
Sequence Identity: 36% (35 aa)

MIKAGWGTKQGGLIKTWKKRWFVLEKDALVYFTKEGGEEQGRIPIGSTCVVSPAPDCKKQPAFKIVTSER-TYFIVTDTQKECSDWISAISNTIA
 || || .|.|  .|.||||||||  . |.|. ... . .| ||. .   | ..|| |..  |.|.| .| ||.. .....|. ||..||.  ..
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDKYRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR
Kinase 81877.m00054.AA AGC 125-381 32 1.9e-181 474.07 In-house 1-395 (395) Show / Hide 
Range on Protein: 125-381
Range on HMM: 1-395/395
Sequence Identity: 32% (131 aa)

FTIIGVLGRGTYGKVQLVKQK------ETGKLFALKTMSKRL-LAETD--QIEQTIVE------------RDLLLKVK----------CPFLVG-AHYTF
| .. |.|.|..||| ||. |       |||..|.| ..|.    ...  ..|.|..|            |. | |..          .||.|   ||.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTDAK--VFMILDYVP---------GG-ELFGRLK---QESSFPESRTRLYAAE-------ILLGLGYLHS-KNYIYRD-LKPENILVDIDGHLRLTDFG
|.. .  ......|.|         || ||| .|.   .| .|.|.|.| ||||       |.|.| |||| ...|.|| ||||||| | |||..|||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAKRATDNE---------------------------------------------------STNSFCG--TPEYIAPEMIQRLPYTKAVDWWS--LGILIF
|.|.  ...                                                    |..|||  ||||.|||..    |.||.||||  ||.|..
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLTGLPPFYDENVN----------QMYRSIL------RDEVAFP----------SHISLAARNLINKLLDKNPATRLGSGPTD-----MEEIKTHPFF
|||||.||||..|..          .|. .|.       ..| ||          ...|  |..||.||| |.|. |||.|. |      |||| ||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 81877.m00054.AA Akt 125-381 49 5.70000000001e-151 485.9 In-house 1-264 (264) Show / Hide 
Range on Protein: 125-381
Range on HMM: 1-264/264
Sequence Identity: 49% (130 aa)

FTIIGVLGRGTYGKVQLVKQKETGKLF-ALKTMSKRLLAETDQIEQTIVERDLLLKVKCPFLVGAHYTFQTDAKVFMILDYVPGGELFGRLKQESSFPES
|... |||.|..||| |||.| |.|.. |.|  .|. . . .|.|.|. || .| ....||.|. || |||  | ....||..|||||  |...  |.|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

RTRLYAAEILLGLGYLHSKNYIYRD-LKPENILVDIDGHLRLTDFGLAKRA--TDNESTNSFCGTPEYIAPEMIQRLPYTKAVDWWS-LGILIFEMLTGL
|.| |.||| |....||||| |||| |||||||.| |||..||||||.|.   .|.. |..|||||||.|||...   .|||||||. ||....||..|.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFYDENVNQMYRSILRDEVAFP--SHISLAARNLINKLLDKNPATRLGSGPTDMEEIKTHPFF
||||.... ||.  |.  .| ||  . || ....||..|| |.|  |||.|| | .||| ||.|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 81877.m00054.AA SGK 125-381 43 1.4e-138 430.78 In-house 1-283 (283) Show / Hide 
Range on Protein: 125-381
Range on HMM: 1-283/283
Sequence Identity: 43% (124 aa)

FTIIGVLGRGTYGKVQLVKQKET------------------GKLFALKTMSKRLLA-------ETDQIEQTIVER-DLLLKVKCPFLVGAHYTFQTDAKV
| .. |.| | .||| .|| |..                  .|..|.|  .|              .   .  || ..| ..| ||.|. || |||. | 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FMILDYVPGGELFGRLKQESSFPESRTRLYAAEILLGLGYLHSKNYIYRDLKPENILVDIDGHLRLTDFGLAK-RATDNESTNSFCGTPEYIAPEMIQRL
.. .||| |||.|  |. | .|||.| | ||||| . |.||||.. ||||||||||| | .||..||||||.|    .|. | .||||||| |||...  
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYTKAVDWWSLGILIFEMLTGLPPFYDENVNQMYRSILRDEVAFPSHISLAARNLINKLLDKNPATRLGSGPTDMEEIKTHPFF
|. ..||||.||.. .||..||||||. |..|||  |.. .  .|  .| .|. ||. || |.|  |||.   | .||| ||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF
Kinase 81877.m00054.AA AktR 125-381 48 1.9e-130 439.69 In-house 1-268 (268) Show / Hide 
Range on Protein: 125-381
Range on HMM: 1-268/268
Sequence Identity: 48% (130 aa)

FTIIGVLGRGTYGKVQLVKQK-ETGKLFALKTMSKRLLAETDQIEQTIVERDLLL-KVKCPFLVGAHYTFQTDAKVFMILDYVPGGELFGRLKQESSFPE
|... .||.|..||| ||. | ...|..|.|  .|  . |  |...|| ||. .  ... ||.|  ||.|||. | | |..|.||||||  ||..  | |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

SRTRLYAAEILLGLGYLHSK-NYIYRDLKPENILVDIDGHLRLTDFGLAK--RAT-DNESTNSFCGTPEYIAPEMIQR-LPYTKAVDWWSLGILIFEMLT
...| |.|.|||.| |||.. | ||||||||||| | |||...|||||.|      ..| ..||||||||.|||||..  ...|.||||..||.|.||.|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GLPPFYDENVNQMYRSILRDE-VAFPSH--ISLAARNLIN-KLLDKNPATRLGSGPTDMEEIKTHPFF
|.||||..| |||. .|.  . . || .  .| ....||. |||.|||  |||..  . |||| ||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 81877.m00054.AA PKA 125-381 44 3.8e-122 412.08 In-house 1-263 (263) Show / Hide 
Range on Protein: 125-381
Range on HMM: 1-263/263
Sequence Identity: 44% (117 aa)

FTIIGVLGRGTYGKVQLVKQKETGKLFALKTMSKRLLAETDQIEQTIVERDLLLKVKCPFLVG-AHYTFQTDAKVFMILDYVPGGELFGRLKQESSFPES
| || .||.|..|.|.|...|..|. .|.|...|.    . |.| .. |.  |. .| ||.|    .|||.| . .|...||||||.| .|  . .|...
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

RTRLYAA-EILLGLGYLHSKNYIYRDLKPENILVDIDGHLRLTDFGLAKRATDNESTNSFCGTPEYIAPEMIQRL-PYTKAVDWWSLGILIFEMLTGLPP
 ...||| .| | | ||||.| ||||||||||| | .||. .|||| ||. .|   | . ||||||.|||.||.  .. |.||||.|||||.|||.| ||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FYDE--NVNQMYRSILRDEVAFPSHISLAA---RNLINKLLDKNPATRLGSGPTDMEEIKTHPFF
|||.  ...|.|. |.  .. ||.|.. .|   . ||.||| ...  |.|.   . . ||.|..|
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 81877.m00054.AA RSK 128-381 41 4e-116 392.09 In-house 1-278 (278) Show / Hide 
Range on Protein: 128-381
Range on HMM: 1-278/278
Sequence Identity: 41% (116 aa)

IGVLGRGTYGKVQLVKQK---ETGKLFALKTMSKRLLAETDQ-IEQTIVERDLLLKVK-CPFLVGAHYTFQTDAKVFMILDYVPGGELFGRLKQESS---
. |||.| |||| |.. .    ||...| |  .|. .. ..  .. |  ||. |. .. .||.|  ||.|||. |...|..|..||||| .|..| .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FPESRTRLYAAEILLGLGYLHSKNYIYRDLKPENILVDI---DGHLRLTDFGLAKR-ATD-NESTNSFCGTPEYIAPEMIQ---RLP-YTKAVDWWSLGI
| |.. . |.||| | . .||..  |.||||||||| |    .||..|||||..|    | |. |..||.| ||.||||.    .   ..||.||||||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LIFEMLTGLPPFYD---ENVNQMYRSILRDE--VAFP--SHISLAARNLINKLLDKNPATRLGSGPTDMEEIKTHPFF
|..||||| |||.    .| ..  . |.. .  . .|  . .| .|..||.|.| ..|. |||.|| |.|||| ||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 81877.m00054.AA RSK-Unclassified 125-381 40 3.6e-112 353.74 In-house 1-283 (283) Show / Hide 
Range on Protein: 125-381
Range on HMM: 1-283/283
Sequence Identity: 40% (114 aa)

FTIIGVLGRGTYGKVQLVKQKETGKLFALKTMSKRLLAETDQIEQTIVERDLLLKVKCPFLVGAHYTFQTDAKVFMILDYVPGGELFGRLK--QESSFPE
|  .. .|.|  ||| ||..|.| ...|.| ..|  .     |   . |.. .   . || |   . |||  . .....| .||..|  |    |  | |
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

SRTRLYAAEILLGLGYLHSKNYIYRDLKPENILVDIDGHLRLTDFGLAKRA----------------------TDNESTNSFCGTPEYIAPEMIQRLPYT
 . | ||.|. . | ||| .  |||||||.||. . .|| .||||.| . |                       .   ||||||| ||.|||||.|   |
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

KAVDWWSLGILIFEMLTGLPPFYDENVNQMYRSILRDEVAFP--SHISLAARNLINKLLDKNPATRLGSGPTDMEEIKTHPFF
|||||| |||...||| |.||.| .| | ..  |.. .| ||  | ||  .| || ||| .||| |||..  | ..|| ||||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 81877.m00054.AA PKC 125-381 40 5.2e-109 354.52 In-house 1-262 (262) Show / Hide 
Range on Protein: 125-381
Range on HMM: 1-262/262
Sequence Identity: 40% (106 aa)

FTIIGVLGRGTYGKVQLVKQKETGKLFALKTMSKRLLAETDQIEQTIVERD-LLLKVKCPFLVGAHYTFQTDAKVFMILDYVPGGELFGRLKQESSFPES
|. . |||.| .||| |...|.| ...| | . | .  ..| .| | .|.  | |  |.|||.. | .|||  . | .. || || |     |   |.|.
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

RTRLYAAEILLGLGYLHSKNYIYRDLKPENILVDIDGHLRLTDFGLAKRA-TDNESTNSFCGTPEYIAPEMIQRLPYTKAVDWWSLGILIFEMLTGLPPF
..| |||||...| .||.|. |||||| .|.|.| .|| ...|||..|   .. . |..|||||.||||| .|  .|.|.||||..|.| .||. | .||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YDENVNQMYRSILRDEVAFPSHISLAARNLINKLLDKNPATRLGSGPTD---MEEIKTHPFF
  |.  .. .||. |.. .| ..|  | ... ....|||..|||..|..    ..|..||||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 81877.m00054.AA S_TKc 125-381 33 7.6e-106 358.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 125-381
Range on HMM: 1-231/231
Sequence Identity: 33% (91 aa)

FTIIGVLGRGTYGKVQLVKQKETGKLFALKTMSKRLLAETDQIEQTIVERDLLLKVKCPFLVGAHYTFQTDAKVFMILDYVPG--GELFGRLKQESS---
..|. ..|.|..||| ... |.||...|.| ..          |... |...| | ..|..|  ...||.  ...|...|..|  |.|| ..|.  .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FPESRTRLYAAEILLGLGYLHSKNYIYRDLKPENILVDIDGHLRLTDFGLAKRATDNESTNSFCGTPEYIAPEMIQRLPYTK-AVDWWSLGILIFEM
   ||| ..| |...|...| |.||.. |.|||||||||.|   |. ..|||||..       ..|||||.|.|||..   .|.| ..||||.|....||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LTGLPPFYDENVNQMYRSILRDEVAFPSHISLAARNLINKLLDKNPATRLGSGPTDM--EEIKTHPFF
|.| |||.  ....|.. |.          |  |...|.|.|.|.|. |..        ..|| ||.|
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81877.m00054.AA p70 125-381 39 1.6e-104 353.59 In-house 1-299 (299) Show / Hide 
Range on Protein: 125-381
Range on HMM: 1-299/299
Sequence Identity: 39% (117 aa)

FTIIGVLGRGTYGKVQLVKQKE---TGKLFALKTMSKRL-------LAETD-------------------QIEQTIVERDLLLKVKCPFLVGAHYTFQTD
|  . |||.| |||| .|.      |||..| | . |.        .| |                    ..|.|  ||  |  || ||..  || |||.
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

AKVFMILDYVPGGELFGRLKQESSFPESRTRLYAAEILLGLGYLHSKNYIYRDLKPENILVDIDGHLRLTDFGLAK-RATDNES----------TNSFCG
 | . ||.| .|||||  |. .. ..|  .. |..|| . |..||..  |||||||||.. .  ||. |||||| |  . | .           | .|||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TPEYIAPEMIQRLPYTKAVDWWSLGILIFEMLTGLPPFYDENVNQMYRSILRDE--VAFPSHISLAARNLINKLLDKNPATRLGSGPTDMEEIKTHPFF
|.|| |||.. |  . .||||||||.|.. |||| |||  ||  .   .||.    .. |   .  .| ||.||| ..|..|.|.|| | ..|. ||||
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 81877.m00054.AA RSK 125-381 37 1.9e-99 336.66 In-house 1-271 (271) Show / Hide 
Range on Protein: 125-381
Range on HMM: 1-271/271
Sequence Identity: 37% (101 aa)

FTIIGVLGRGTYGKVQLVKQK---ETGKLFALKTMSKRLLAETDQIEQTIVERDLLLKVKCPFLVGAHYTFQTDAKVFMILDYVPGGELFGRLKQESSFP
. .. ..|.|...|| ..| .    |....| |   |  .. .|.  ..  ||..|  .  || |  || ||.  ||.||.|   ||.||.||  . .|.
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

ESRTRLYAAEILLGLGYLHSKNYIYRDLKPENILVDID----GHLRLTDFGLAKRATDNES-TNSFCGTPEYIAPEMIQRLPYTKAVDWWSLGILIFEML
|.  . |.|||.| . ||||.  ..|||||||||.| .    ||....|||.|| . | .  . .||.| .|.|||.. |  ...|.||||.|.| .|||
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

TGLPPFYDENVNQMYRSILRDEVAF-------PSHISLAARNLINKLLDKNPATRLGSGPTDMEEIKTHPFF
|| .||.  . . .   |.|  ..        .. ||  |  |. ..|. .|. |||.|| . |.|| ||.|
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 81877.m00054.AA Pkinase 125-381 29 5.3e-90 310.12 Pfam 1-293 (293) Show / Hide 
Range on Protein: 125-381
Range on HMM: 1-293/293
Sequence Identity: 29% (90 aa)

FTIIGVLGRGTYGKVQLVKQKETGKLFALKTMSKRLLAETDQIEQTIV--ERDLLLKVKCPFLVGAHYTFQTDAKVFMILDYVPGG----ELFGRLK--Q
..|....|.|..|.| . . | |||..|.|...||  .. .. .. .   |  .......|. |  ...|... .. |...|..||    .|| ...  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

ESSF--PESRTRLYAAEILLGLGYLHSKNYIYRDLKPENILVDIDGHL----RLTDFGLAKR--ATDNESTNSFCGTPEYIAPEMIQ-RLPYTKAVDWWS
. .|  .|   . |. .|| || |.||.. |.|||||||||.| .||.    ...||||||      |. ...|||||.|.||| |. . .|...||.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGILIFEMLTGLPPFYDE------NVNQMYRSILRDEVAFPSHIS---------------------LAARNLINKLLDKNPATRLGSGPTDMEEIKTHPF
.|....|||.| |||...      . .||.. |.. .. |..  .                      ... .|...|.|.|. |..      |.|. ||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPW

F
|
F
Kinase 81877.m00054.AA TyrKc 125-381 20 4.4e-14 4.98 SMART 1-280 (280) Show / Hide 
Range on Protein: 125-381
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

FTIIGVLGRGTYGKVQLVKQKETGKLFALKTMSKRLLAETDQIEQTIVERDLLLKV--KCPFLVGAHYTFQTD-------AKVFMILDYVPGGELFGRLK
 | . .||.| .|.| . . |       ..   | | ...  .|  . |  .. |.  . | .|  .    ..         ..... |.|.| |  .|.
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QESS-FPESRTRLYAAEILLGLGYLHSKNYIYRDLKPENILVDIDGHLRLTDFGLAKRATDN----ESTNSFC-----GTPE-----YIAPEMIQRLPYT
     .. .    ..  |  |  ||||||.| |||   |.||. ... . .||||..  .|     ||.         |.         ||| |.   .|
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KAVDWWSLGILIFEMLT-GLPPFYD-----ENVNQMYRSILRD-EVAFPSH--------ISLAARNLINKLLDKNPATRLGSGPTDMEEIKTHPFF
 . | || |....|..| | .| ..      .  .... . .      | .         . .  ... .  . .|. |       ..||  | .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP-----TFSEI--HECF
Kinase 81877.m00054.AA S_TK_X 382-445 28 1.8e-08 35.35 SMART 1-79 (79) Show / Hide 
Range on Protein: 382-445
Range on HMM: 1-79/79
Sequence Identity: 28% (23 aa)

KDLNWSEVEE--KKVKPEWVPEIK----DATDTSCFDEEFTQETGGVSFEDGSLIGHDTQQQ----------FTGFTCTQ
....|  ..   |...| ..|.||    ..|||| ||.||| ||      | . . .  .|.          | |||   
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM-LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 81877.m00054.AA Pkinase_Tyr 197-334 27 2.3e-08 28.96 Pfam 81-228 (270) Show / Hide 
Range on Protein: 197-334
Range on HMM: 81-228/270
Sequence Identity: 27% (41 aa)

KVFMILDYVPGGELFGRLKQ----ESSFPESRTRLYAAEILLGLGYLHSKNYIYRDLKPENILVDIDGHLRLTDFGLAKRATDNEST-NSFCGTPE---Y
...... |.|.| |   |..    . ... ..   ....|  |. ||.|||.| |||   |.||. ... . .|||||.  .. .    .  |..     
QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKW

IAPEMIQRLPYTKAVDWWSLGILIFEMLT-GLPP-FYDENVNQMYRSI
 ||| |.   .| . | || |.|..|..| |  | ...   ...|. |
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI
Kinase 81877.m00054.AA Pkinase_C 401-442 40 4e-06 24.7 Pfam 1-41 (46) Show / Hide 
Range on Protein: 401-442
Range on HMM: 1-41/46
Sequence Identity: 40% (17 aa)

EIKDATDTSCFDEEFTQETGGVSFEDGSLIGHDTQQQFTGFT
..|..|||| ||.|||.|.   .. |.. .    | .| |||
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFT
Kinase 81877.m00054.AA Pkinase_Tyr 125-139 40 1.992118 2.07 Pfam 1-15 (270) Show / Hide 
Range on Protein: 125-139
Range on HMM: 1-15/270
Sequence Identity: 40% (6 aa)

FTIIGVLGRGTYGKV
 |.. .||.| .|.|
ITFGKKLGEGAFGEV