Gene 80906.m00389 (T.vaginalis)
80906.m00389
Species: T.vaginalis
Alias: 80906.m00389, TvagK0361
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 80906.m00389.AA | Protein | None | 729 | None | Fasta, JSON |
| 80906.m00389.kin_dom | Protein Kinase Domain | None | 262 | None | Fasta, JSON |
Protein domains of 80906.m00389.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 80906.m00389.AA | AGC | 330-591 | 26 | 2e-116 | 302.05 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 330-591 Range on HMM: 1-395/395 Sequence Identity: 26% (106 aa) FTILKQISKGAYARVYLAEKN------STKDKYAIKVISKDK-LHTTEI-VKHHLLHE------------KDFLFQLR----------SNFIVK-IYSSF | .|| |.||.. .|||..|. .|.. ||.||..|.. .. .| . | .. | ... . |||| ..|| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF IGEKN--LYIVMDYIS---------NG-DLKHIL--D-NYEVFDEVHATICTAQ-------IVLALRDLRR-NKFVHRD-LKPDNVLLDGDGYLKLIDFG ... ||.||.|.. | .| ..| . .. .||| .| . .|. ||||| | . ....||| |||.|.||| ||..|| ||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LSSEIMQNEIV----------------------------------------------------DTTG--TLGYCSPEVLTNQATTYSSDYWS--LGCMIY |. |.|... . | | | .||.| ... |.|| |||..| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY EFLFGMPPFNAEN----------ATKTIENTLKINY--EVDLSLTAN------PDNDL-HDALDLISKLLVFEPEKRLGQNS-------FEDIMNHPWF |.|.| |||...| .. .. .. .| . .. . . .| . .| |||.|||. .|||||| . .|.|.||||| EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | 80906.m00389.AA | S_TKc | 330-591 | 30 | 1.8e-81 | 277.9 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 330-591
Range on HMM: 1-231/231
Sequence Identity: 30% (85 aa)
FTILKQISKGAYARVYLAEKNSTKDKYAIKVISKDKLHTTEIVKHHLLHEKDFLFQLRSNFIVKIYSSFIGEKNLYIVMDYISN--GDLKHILDNYEV--
..||..| |||...||.. ...|. ..|||.|. |.. | . | . . .|||.| .| ..||.||.|... |||.......
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG
----FDEVHATICTAQIVLALRDLRRNKFVHRDLKPDNVLLDGDGYLKLIDFGLSSEIMQNEIVDTTGTLGYCSPEVLTNQATTY-SSDYWSLGCMIYEF
|.| || ..||..|| . .....||||||.|.||| .|..||||. .. ||. |..|||| .. ..| ||.||..||.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM
LFGMPPFNAENATKTIENTLKINYEVDLSLTANPDNDLHDALDLISKLLVFEPEKRLGQNSFED----IMNHPWF
| | ||| . ..... . ..|.|.|.|.|...||||.. |..||||
LCGYPPFP--QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | 80906.m00389.AA | Ciliate-E2 | 330-591 | 22 | 1.4e-75 | 257.41 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 330-591 Range on HMM: 1-365/365 Sequence Identity: 22% (88 aa) FTILKQISKGAYARVYLAEKNST--------------------KDK---YAIKVISKDKLHTTEIVKHHLL---------HEKDFLFQLRSNFIVKIYSS . ..|.| .|... ||.... .. |.| ||.|...|... .. ..| . || |.|| ...|.|.| . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FI--GEKNLYIVMDYISNGDLKHILD------------NYEVFDEVHATICTAQIVL---------------ALRDLRRNK-FVHRDLKPDNVLLDGDGY |. ..|.|.||.|.. |||.... . |.| .. ..||. ||. | .. .|||.||.|.|. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----- LKLIDFGLSSEIMQNEIVDT---------------------------------TGTLGYCSPEVLTNQA---------TTYSSDYWSLGCMIYEFLFGMP .|.|||||| .. .... | ||.|| .||.| .. .|..|.||||...||.||| | IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP PFNAENATKTIENTLKINYEVDLSLTAN---------------PDNDLHDALDLISK----LLVFEPEKRLGQNSFEDIMNHPWF || .... . .... . ... .. |||.| .|. .||||.. ..|.|.||||| PF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF |
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| Kinase | 80906.m00389.AA | Ciliate-E2-Unclassified | 330-591 | 25 | 2.9e-73 | 249.71 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 330-591
Range on HMM: 1-352/352
Sequence Identity: 25% (91 aa)
FTILKQISKGAYARVYLAEKNSTKDKYAIKVISKDKLHTTEIVKH--------HLLHEKD-------------FLFQLRSNFIVKIYSSFIGEKNLYIVM
..|.||| .|... ||.......| .||.| ..| . .... . . .| | .. . |||| . | ..|.||||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM
DYISNGDLKHILDNYEV-----------------FDEVHAT-----ICTAQIVLALRDLRRNK-FVHRDLKPDNVLLDGDG---YLKLIDFGLSSEIM--
.|. .|||. .. ... |.| .| .|||...| | ... ..|||.||.|.|.| .| |.|.||||.|...
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN
---------------QNEIVDTTGTLGYC----SPEVLTNQATT----YSSDYWSLGCMIYEFLFGMPPFNAENATK------------TIENTLKINYE
|... ...||..| .|||| .| |..|.||||. .||.||| .||...| .. .... ... ..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ
VDLSLTANPD----NDLHDAL-----DLISKLLVFEPEKRLGQNSFEDIMNHPWF
... | .... ||..|.|. |.||. .||.|.|||||
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI---TFEQILNHPWF
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| Kinase | 80906.m00389.AA | AktR | 330-591 | 34 | 3.4e-69 | 236.18 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 330-591 Range on HMM: 1-268/268 Sequence Identity: 34% (97 aa) FTILKQISKGAYARVYLAEKN-STKDKYAIKVISKDKLHTTEIVKHHLLHEKDFLF-QLRSNFIVKIYSSFIGEKNLYIVMDYISNGDLKHILDNYEVFD |...| . |||...|||..|. ....||.|.|.| | . .||.. |.. . . . .|||| . .| ...|...|.|. .|.| ..| . . |. FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKK-KKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFS EVHATICTAQIVLALRDLRRN-KFVHRDLKPDNVLLDGDGYLKLIDFGLSS-EIMQ-NEIVDTT--GTLGYCSPEVLTN-QATTYSSDYWSLGCMIYEFL | | . |||.||| | . . . |||||.| ||| ||..|..||||| ..| .. . .. || | .||..|. . ..|.|.|..|. ||| . EEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMV FGMPPFNAEN----ATKTIENT-LKINYEVDLSLTANPDNDLHDALDLIS-KLLVFEPEKRLG--QNSFEDIMNHPWF .|.|||...| | .. . .|..| ...| .. ||| ||| |.|||| |..|.| .|||| TGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCK---------DLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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| Kinase | 80906.m00389.AA | Pkinase | 330-591 | 27 | 2.4e-63 | 221.57 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 330-591 Range on HMM: 1-293/293 Sequence Identity: 27% (81 aa) FTILKQISKGAYARVYLAEKNSTKDKYAIKVISKDKLHTTEIVKHHLLHEKDFLFQLRSNFIVKIYSSFIGEKNLYIVMDYISNG----DLKHILD--NY ..|...| .|....||.. . .| ...|.|.|.|.. . . . | .| | . |.. .||..| .| ....|.||.| .| ||.... .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH EVF--DEVHATICTAQIVLALRDLRRNKFVHRDLKPDNVLLDGDGYL----KLIDFGLSSE--IMQNEIVDT-TGTLGYCSPEVLT-NQATTYSSDYWSL .| .| .. . ||. .| . .....||||||.|.|.| .|.. |..||||. . |. .| .||..|..|||. .| ....| ||. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GCMIYEFLFGMPPFNAE------NATKTIENTLKINYEVDLSLT---------------ANPDNDLHDALDLISKLLVFEPEKRLGQNSFEDIMNHPWF ||..||.|.| ||| . . . |..... .. | . . . .| ...|.|...| . |.||.. .|.|..|||| GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF |
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| Kinase | 80906.m00389.AA | CAMK | 335-591 | 18 | 4.2e-63 | 201.88 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 335-591
Range on HMM: 1-425/425
Sequence Identity: 18% (81 aa)
QISKGAYARVYLAEKNSTK------------DKYAIKVISKDKLHT------------------------TEIVKHHLLHEKDFLFQ-------LRSNFI
.. .|... |.|.. .|. |.|||.|.|.|| .. .. ...| . . . |. |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VKIYSSFIG-------------------EKNLYIVM---DYISNG----D-LKHILDN-Y-------------EVFDEVHATICTAQIVLALRDLRRNKF
.|.| . .|..|.|| .|.|.| | . .| .. . |.| | . ||. |.. . ..
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
VHRDLKPDNVLLDGDG----------------Y-LKLIDFGLSSEIMQNE-------------------------IVDTTGTLGYCS-PEVLTN------
|||||||.|.||| .. . .|.||||.. .....| . ||..|.. ||||
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
--------QATTYSSDYWSLGCMIYEFLFGMPPFNAEN---------ATKTIENTLKINYEVDLSLTANP--------DNDLHD-------------ALD
. ....| ||.|.. | | | |||.... .......... . . . . ... | . |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LISKLLVFEPEKRLGQNSFEDIMNHPWF
||.|.|. .||||. . |...||||.
LIRKMLQVDPEKRM---TIEQCLNHPWM
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| Kinase | 80906.m00389.AA | SGK | 330-591 | 32 | 1.1e-61 | 189.07 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 330-591
Range on HMM: 1-283/283
Sequence Identity: 32% (93 aa)
FTILKQISKGAYARVYLAEKNST------------------KDKYAIKVISKDKLH-------TTEIVKHHLLHEKDFLFQLRSNFIVKIYSSFIGEKNL
| .|| | || . .||.... .. ...||.||..|. . .|| . ... | ... |||. .| .. |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL
YIVMDYISNGDLKHILDNYEVFDEVHATICTAQIVLALRDLRRNKFVHRDLKPDNVLLDGDGYLKLIDFGLSSEIMQNEIVDTT--GTLGYCSPEVLTNQ
| ||||. |.. | | | | . .|.||.|| | . ..|||||.|.||| .|...| ||||. | .. . .| ||. | |||| |
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ
ATTYSSDYWSLGCMIYEFLFGMPPFNAENATKTIENTLKINYEVDLSLTANPDNDLHDALDLISKLLVFEPEKRLGQN-SFEDIMNHPWF
. | |.||| ||...|.||| | .| .. . .. || ||| || .|.|||| . |..| |||.|
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSN-------DAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
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| Kinase | 80906.m00389.AA | Akt | 330-531 | 36 | 4.1e-52 | 164.84 | In-house | 1-207 (264) | Show / Hide |
Range on Protein: 330-531 Range on HMM: 1-207/264 Sequence Identity: 36% (76 aa) FTILKQISKGAYARVYLAEKNSTKDKY-AIKVISKDKLHTTEIVKHHLLHEKDFLFQLRSNFIVKIYSSFIGEKNLYIVMDYISNGDLKHILDNYEVFDE |..|| . ||....|.|..|..|.. | |.||..||.. |. | . |. | ...|||. . || ...||.||||.. |.| | ..|.| FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVE-HTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE VHATICTAQIVLALRDLRRNKFVHRD-LKPDNVLLDGDGYLKLIDFGLSSEI-MQN-EIVDT-TGTLGYCSPEVLTNQATTYSSDYWS-LGCMIYEFLFG | |.|.||. | . . || ||| |.|.| ||...| ||||. |. ... .. .| || | .||.| .. | ..| |. ||| .||...| DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG MPPFNAEN .||| ... RPPFYNQD |
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| Kinase | 80906.m00389.AA | MAST | 330-476 | 42 | 4.5e-49 | 156.14 | In-house | 1-146 (334) | Show / Hide |
Range on Protein: 330-476 Range on HMM: 1-146/334 Sequence Identity: 42% (63 aa) FTILKQISKGAYARVYLAEKNSTKDKYAIKVISKDKLHTTEIVK---HHLLHEKDFLFQLRSNFIVKIYSSFIGEKNLYIVMDYISNGDLKHILDNYEVF |.. | |||||| .|||.....|.| .|.||| |. . | | ... |.. | .....|.||...|| ...|..||.| . ||....| .| | FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDM----INKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYF DEVHATICTAQIVLALRDLRRNKFVHRDLKPDNVLLDGDGYLKLIDFGLS || | . .|..||.| | . |||||||||.|.| .| || ||||| DEWMAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLS |
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| Kinase | 80906.m00389.AA | MAST | 330-476 | 39 | 2.1e-46 | 139.37 | In-house | 1-149 (337) | Show / Hide |
Range on Protein: 330-476 Range on HMM: 1-149/337 Sequence Identity: 39% (61 aa) FTILKQISKGAYARVYLAEKNSTKDKYAIKVISKDKLHTTEIVK---HHLLHEKDFLFQLRSNFIVKIYSSFIG--EKNLYIVMDYISNGDLKHILDNYE | ..| |||||| .|||... .|.| .|.||| .. . | | .. |.. | .. .|.||...|| .| |..||.| . || ..| .| FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDT----IDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYG -VFDEVHATICTAQIVLALRDLRRNKFVHRDLKPDNVLLDGDGYLKLIDFGLS ..| | . .|..||.| | |||||||||.|.|..| .|| ||||| NCMPEWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLS |
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| Kinase | 80906.m00389.AA | NDR | 330-491 | 32 | 1e-45 | 138.58 | In-house | 1-175 (350) | Show / Hide |
Range on Protein: 330-491 Range on HMM: 1-175/350 Sequence Identity: 32% (58 aa) FTILKQISKGAYARVYLAEKNSTKDKYAIKVISKDKLHTTEIVKHHLLHEKDFLFQLR--SNFIVKIYSSFIGEKNLYIVMDYISNGDLKH---ILDNYE |.|.|.|.|||. .|.|. |..|.. ||.|.. | . .. |.| .. |.| . . . ....|| | ||. ...|| ||.|. ||.. .| ... FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAH-VRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMD VFDEVHATICTAQIVLALRDLRRNKFVHRDLKPDNVLLDGDGYLKLIDFGLSSEIMQ----------NEIVDTTGTL .|.| .| | .|.|. .. .. ..|||.|||| |.| || .||.||||. . |. ... |. |. IFTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPM-TTYSTF |
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| Kinase | 80906.m00389.AA | MAST | 489-591 | 35 | 1.6e-27 | 85.52 | In-house | 226-334 (334) | Show / Hide |
Range on Protein: 489-591 Range on HMM: 226-334/334 Sequence Identity: 35% (41 aa) GTLGYCSPEVLTNQA-TTYSSDYWSLGCMIYEFLFGMPPFNAENATKTIENTLKIN------YEV-----DLSLTANPDNDLHDALDLISKLLVFEPEKR ||..| .|||...| ..|.||.| ..|||| | |||| .. ... .|.|. | .|. | .. .| |||.||| |.|| GTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSP-------EAQDLIEKLLQPDPRKR LGQN-SFEDIMNHPWF || | .....|| | LGANNGADEVKQHPFF |
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| Kinase | 80906.m00389.AA | NDR | 493-591 | 30 | 1.1e-26 | 78.84 | In-house | 247-350 (350) | Show / Hide |
Range on Protein: 493-591 Range on HMM: 247-350/350 Sequence Identity: 30% (35 aa) YCSPEVLTN-QATTYSSDYWSLGCMIYEFLFGMPPFNAENATKTIEN------TL-----KINYEVDLSLTANPDNDLHDALDLISKLLVFEPEKRLGQN | |||... . . . |.|||||. ||.|.| |||.... ..| .. |. . .|. || .| ||| .|. .|..||| . YMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLS---------PEAWDLIRRLCCPDPDHRLGSH S--FEDIMNHPWF ...| .||.| GKGVDEIKSHPFF |
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| Kinase | 80906.m00389.AA | MAST | 493-591 | 37 | 2.8e-25 | 73.63 | In-house | 234-337 (337) | Show / Hide |
Range on Protein: 493-591 Range on HMM: 234-337/337 Sequence Identity: 37% (39 aa) YCSPEVLTNQA-TTYSSDYWSLGCMIYEFLFGMPPFNAENATK-TIENTLKINYEVDLSLT--ANPDNDL-HDALDLISKLLVFEPEKRLGQNSFEDIMN | .|||.. | . |.||.| ..|||| | ||||... . . .|... . |. . | |. . .| |||.||| | |||| | ..|.. YIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGADEIKQ HPWF || | HPFF |
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| Kinase | 80906.m00389.AA | TyrKc | 330-591 | 20 | 9e-15 | 16.13 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 330-591 Range on HMM: 1-280/280 Sequence Identity: 20% (62 aa) FTILKQISKGAYARVYLAEKNSTKDKYAIKVISKDKLHTTEIVKHHLLHEKDFLFQL--RSNFIVKIYSSFIGE-------KNLYIVMDYISNGDLKHIL | .|.. ||. .||... . . |.|.. .|. . ...| . .| . ||..| . . . |.||| | ..||||. | ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL DNYEV-FDEVHATICTAQIVLALRDLRRNKFVHRDLKPDNVLLDGDGYLKLIDFGLSSEIMQN--------EIV-----DTT--GTLGYCSPEVLTNQAT ... . . || . | .....|||| |.|.. .. | ||||| .| .. .. . ..||.. RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF TYSSDYWSLGCMIYEFL-FGMPPFNAE----NATKTIENTLKINYEVDLSLTANPDN--------DLHDALDLISKLLVFEPEKRLGQNSFEDIMNHPWF | || || | ...| . .|..| . . . . .| | . |.| . ..... ..||.| .|..| | | TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQ-----PPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP---TFSEI--HECF |
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| Kinase | 80906.m00389.AA | Akt | 560-591 | 50 | 4.6e-11 | 31.52 | In-house | 231-264 (264) | Show / Hide |
Range on Protein: 560-591 Range on HMM: 231-264/264 Sequence Identity: 50% (17 aa) DALDLISKLLVFEPEKRLG--QNSFEDIMNHPWF .. ||||.|| |.|||| | ..|..|||| ECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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| Kinase | 80906.m00389.AA | Pkinase_Tyr | 330-420 | 25 | 2.2e-05 | 18.88 | Pfam | 1-98 (270) | Show / Hide |
Range on Protein: 330-420 Range on HMM: 1-98/270 Sequence Identity: 25% (26 aa) FTILKQISKGAYARVYLAEKN----STKDKYAIKVISKDKLHTTEIV--KHHLLHEKDFLFQL-RSNFIVKIYSSFI-GEKN--LYIVMDYISNGDLKHI |..|.. .||. .||... . .|| . |.|.. |. .... . ...| . || . ||. | . .. .|||| | .|||.. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY L | L |
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| Kinase | 80906.m00389.AA | Pkinase_Tyr | 447-519 | 28 | 0.027866 | 8.35 | Pfam | 129-206 (270) | Show / Hide |
Range on Protein: 447-519 Range on HMM: 129-206/270 Sequence Identity: 28% (22 aa) RNKFVHRDLKPDNVLLDGDGYLKLIDFGLSSEI-MQNEI-VDTTGTLG---YCSPEVLTNQATTYSSDYWSLGCMIYE .....|||| |.|.. .. | ||||. | . . ..|. ..||.. . | || || | ..| SKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWE |
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