Gene 95940.m00220 (T.vaginalis)

95940.m00220

Species: T.vaginalis
Alias: TvagK0610, 95940.m00220
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDC2

Sequence

Name Sequence Type Origin Length Description Download
95940.m00220.AA Protein None 308 None Fasta, JSON
95940.m00220.kin_dom Protein Kinase Domain None 282 None Fasta, JSON

Protein domain

Protein domains of 95940.m00220.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 95940.m00220.AA CDC2 6-287 53 7.70000000001e-178 551.65 In-house 1-301 (301) Show / Hide 
Range on Protein: 6-287
Range on HMM: 1-301/301
Sequence Identity: 53% (161 aa)

FTKKEKLGEGTYGVVYRAVDNRTGEIVALKQMRLEQEEEG--IPVTALREIALMRNLN-HQNIVALKDVISTKGALTMVSEYLEFDLRKYMD---STRTG
..| ||.|||||||||.. |..|..|||||. |||||.||  .| ||.||| .. .|. |.||| |.|||     | || |||..||.||||   .... 
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

VHPALLKSYAFQLLCGICYLHSNRIMHRDMKPQNLLINKDGFLKICDFGLARTFTIPPRQYT--HEVVTLWYRPVELLMNSPLYDISVDVWGTGCIIAEM
. |.|.|||..|.| |....|..|||||| ||||.||.|.| .|| ||||||.|.|| |.||  |||||||||. |.|. .  |...||.|  |||.|||
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---ISGNPLFPGDSEIDQLFKIFRVFGTPTEETWPGFTRLPGYQPTFPKFPEQNLAEVLHC---------NNDLLVDLLKQLLEINPSKRISAMRALQHP
   ..  |||.|||||||||||||..|||.|.|||| | || |..|||....|.| ...           ...  .|||.|.| ..|.||||| .|||||
FMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHP

FF
.|
YF
Kinase 95940.m00220.AA CDK 6-287 49 6.00000000001e-162 522.05 In-house 1-284 (284) Show / Hide 
Range on Protein: 6-287
Range on HMM: 1-284/284
Sequence Identity: 49% (159 aa)

FTKKEKLGEGTYGVVYRAVDNRTG-----EIVALKQMRLEQ-----EEEGIPVTALREIALMRNLNHQNIVALKDVISTK-----------GALTMVSEY
. | ||.|||||||||.| | .||     .|||||. |.|.     |.||.| ||.|||.|...| |.||| |.||. ||             |.|| ||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

LEFDLRKYMDSTRTGVHPALLKSYAFQLLCGICYLHSNRIMHRDMKPQNLLINKDGF-----LKICDFGLARTFTI------PPRQYTHEVVTLWYRPVE
.. || ||||           |.| .||| |. |.|||.|||||.||||.|||..|      ||| |||||| | |      | | |||||||||||. |
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

LLMNSPLYD--ISVDVWGTGCIIAEMIS---GNPLFPGDSEIDQLFKIFRVFGTPTEETWPGFTRLPGYQPTFPKFPEQNLAEVLHCNNDLLVDLLKQLL
||. |  |.   ..|.|. |||.|||.    . |||||||||||||||||..|||||..|||.| ||.|                        ||| ..|
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------------DLLNKML

EINPSKRISAMRALQHPFF
  .|.|||||  |||||.|
CYDPKKRISAEQALQHPYF
Kinase 95940.m00220.AA CDK5 6-287 50 6.2e-152 483.68 In-house 1-287 (287) Show / Hide 
Range on Protein: 6-287
Range on HMM: 1-287/287
Sequence Identity: 50% (145 aa)

FTKKEKLGEGTYGVVYRAVDNRTGEIVALKQMRLEQEEEGIPVTALREIALMRNLNHQNIVALKDVISTKGALTMVSEYLEFDLRKYMDSTRTGVHPALL
. | ||.||||||.||.| .  |.||||||. ||..| ||.| ||.|||.|.. | |.||| | ||| .   ||.| |..  ||.|||||   .. ... 
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

KSYAFQLLCGICYLHSNRIMHRDMKPQNLLINKDGFLKICDFGLARTFTIPPRQYTHEVVTLWYRPVELLMNSPLYDISVDVWGTGCIIAEMI-SGNPLF
||. .||| |. . |.....|||.||||||||| | ||  |||||| | || | |.||||||||||   || | .|  |.|.|  |||.|||. .| |||
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

PGDSEIDQLFKIFRVFGTPTEETWPGFTRLPGYQ---PTFPKFPEQN-LAEVLHCNNDLLVDLLKQLLEINPSKRISAMRALQHPFF
|| .. |||..||.. |||.|..||. | || |.     .|..| .  .... .  .  . |||...|..|| .||||  ||.||.|
PGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase 95940.m00220.AA CMGC 6-287 26 8.60000000001e-142 469.22 In-house 1-513 (513) Show / Hide 
Range on Protein: 6-287
Range on HMM: 1-513/513
Sequence Identity: 26% (136 aa)

FTKKEKLGEGTYGVVYRAVD--------------NRTGEIVALKQMRLEQ---------EEEGIPVTALREIALMRNLN-----------------HQNI
... .|.|||||||||...|              ..|.||||.| .....         |..|.| .||||| ....||                 | ||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VALKDVISTKG-----------------ALTMVSEYLEFDLRKYMDSTRT------GVHP-------------ALLKSYA------FQLLCGIC--YLHS
| |.|.. .|.                  | .| ||.. || .|......      ...               . |..       .|.|.|.   |.||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHS

NR--IMHRDMKPQNLLINKD--------------------GFLKICDFGLARTFTIPPRQ---------------------YTHEVVTLWYRPVELLMNS
..  |.|||.||.|.|||..                    | |||||||||| . .....                     |||.|||.|||. |.|...
HWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGW

PLYD---------ISVDVWGTGCIIAEMISG--------NPLFPGDSE-----------IDQLFKIFRVFGTPT---------------EETWPGFTRLP
. |.          ..|.|. |||.|||. |         |||||.||           ||||||||.|.||||               ||.||... ||
KHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLP

GYQP--------------T------------FPKFPEQNLAEVLHCNN-----------------------------------DLLVDLLKQLLEINPSK
.|..              .            ||..| ... ..  ...                                   ....||||..|...|.|
WYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDK

RISAMRALQHPFF
||.|  |||||.|
RITAEQALQHPYF
Kinase 95940.m00220.AA CDK7 6-287 40 1.4e-133 358.25 In-house 1-288 (288) Show / Hide 
Range on Protein: 6-287
Range on HMM: 1-288/288
Sequence Identity: 40% (116 aa)

FTKKEKLGEGTYGVVYRAVDNRTGEIVALKQMR----LEQEEEGIPVTALREIALMRNLNHQNIVALKDVISTKGALTMVSEYLEFDLRKYMDSTRTGVH
..| ...|||....||.| |  ||.||| |  .     .. . ||  ||.||| . . . | |.. | |..  |  . .| .... ||            
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

PALLKSYAFQLLCGICYLHSNRIMHRDMKPQNLLINKDGFLKICDFGLARTFTIPPRQYTHEVVTLWYRPVELLMNSPLYDISVDVWGTGCIIAEMISGN
||  |.|. ..| |. |.| | | |||.|| |||.|..| ||| |||||| .  | | ||| ||| |||  |||     |  .||.|  |||.|| .  .
PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRV

PLFPGDSEIDQLFKIFRVFGTPTEETWPGFTRLPGYQPTFPKFPE---QNLAEVLHCNNDLLVDLLKQLLEINPSKRISAMRALQHPFF
| .||||.|||| .||.  ||||||.||. . .. |  .| .||.     | ..     | |.||.. ..  ||.||...  .|..|.|
PYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYI-KFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase 95940.m00220.AA PITSLRE 6-287 47 1.2e-117 397.17 In-house 1-295 (295) Show / Hide 
Range on Protein: 6-287
Range on HMM: 1-295/295
Sequence Identity: 47% (139 aa)

FTKKEKLGEGTYGVVYRAVDNRTGEIVALKQMRLE--QEEEGIPVTALREIA-LMRNLNHQNIVALKDVI--STKGALTMVSEYLEFDLRKYMDSTR---
| .  . .||||||||||.| ||.|||||| . .|  .| ||.|.|.||||  . . |.| |||..| ..  |..    || ||.| ||.  |.  .   
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

TGVHPALLKSYAFQLLCGICYLHSNRIMHRDMKPQNLLINKDGFLKICDFGLARTFTIPPRQYTHEVVTLWYRPVELLMNSPLYDISVDVWGTGCIIAEM
    |   |.   ||| |. ..|.| ||||| |  |||..  | |||||||||| .  | . ||  |||||||  |||  ...|   ||.|  ||| ||.
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF

ISGNPLFPGDSEIDQLFKIFRVFGTPTEETWPGFTRLPGYQP-T-FPKFPEQNLAEVLH---CNNDLLVDLLKQLLEINPSKRISAMRALQHPFF
|.. |||.|.|||||. .||  .|||||  |||.| ||.    . ||. |. || .        .|   ||| |.|. || .||.|  ||.||.|
ITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase 95940.m00220.AA PFTAIRE 6-287 47 7.1e-116 391.27 In-house 1-287 (287) Show / Hide 
Range on Protein: 6-287
Range on HMM: 1-287/287
Sequence Identity: 47% (138 aa)

FTKKEKLGEGTYGVVYRAVDNRTGEIVALKQMRLEQEEEGIPVTALREIALMRNLNHQNIVALKDVISTKGALTMVSEYLEFDLRKYMDSTRTGVHPALL
. | ||||||.|  ||...   .. .||||  || |.||| | || ||  |..|| | ||| | |.| ||  ||.| ||.. || .|||.   | ||   
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRL-QQEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGMHPNNV

KSYAFQLLCGICYLHSNRIMHRDMKPQNLLINKDGFLKICDFGLARTFTIPPRQYTHEVVTLWYRPVELLMNSPLYDISVDVWGTGCIIAEMISGNPLFP
. . |||| |  | |  |..|||.||||||| . | ||  ||||||   .| . | ||||||||||   |. |  |  ..|.|| |||  ||. | |.||
RLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAFP

GD-SEIDQLFKIFRVFGTPTEETWPGFTRLPGYQPTFPK---FPEQNLAEVLHCNN--DLLVDLLKQLLEINPSKRISAMRALQHPFF
|     ||| |||.| |||||.|||| ..||.|.|   .   .  ..| ...          ||....| ..| .|.||  |.|||.|
GMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase 95940.m00220.AA PCTAIRE 6-287 46 4e-110 372.14 In-house 1-291 (291) Show / Hide 
Range on Protein: 6-287
Range on HMM: 1-291/291
Sequence Identity: 46% (136 aa)

FTKKEKLGEGTYGVVYRAVDNRTGEIVALKQMRLEQEEEGIPVTALREIALMRNLNHQNIVALKDVISTKGALTMVSEYLEFDLRKYMDSTRTGVHPALL
..| .|||||||  ||.     |. .||||  |||  ||| | || ||. |...| | ||| | |.| |  .||.| ||.. ||..|||    ..     
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLEH-EEGAPCTAIREVSLLKDLKHANIVTLHDIIHTHHQLTLVFEYMDMDLKQYMDDCGNIMNMHNV

KSYAFQLLCGICYLHSNRIMHRDMKPQNLLINKDGFLKICDFGLARTFTIPPRQYTHEVVTLWYRPVELLMNSPLYDISVDVWGTGCIIAEMISGNPLFP
| . |||| |  | |  .|.|||.|||||||| .| ||  ||||||   .| . | |||||||||| . || |  |  ..|.|| ||| .|| .| ||||
KLFLFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGRPLFP

GDS------EIDQLFKIFRVFGTPTEETWPGFTRLPGYQP-TFPKFPEQNLAEVLHCNN---DLLVDLLKQLLEINPSKRISAMRALQHPFF
|          |||  |||. |||.|.|||| . ......  ||...|| |  .            |||..||   . .|.||  |..||.|
GSTDSHYPGVKDQLHMIFRILGTPDEKTWPGVKSNEEFRTYNFPRYREQPLINHAPRLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPYF
Kinase 95940.m00220.AA Pkinase 6-287 33 5.9e-98 336.54 Pfam 1-293 (293) Show / Hide 
Range on Protein: 6-287
Range on HMM: 1-293/293
Sequence Identity: 33% (102 aa)

FTKKEKLGEGTYGVVYRAVDNRTGEIVALKQMRLEQEEEGIPVTALR--EIALMRNLNHQNIVALKDVISTKGALTMVSEYLEF-----DLRKYMD-STR
.....|.|.|..|.||....  ||.|||.|..... |... ..|..|  ||..|..||| ||| |.|.  .|. . || ||.|      ||  |.  . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

TGV--HPALLKSYAFQLLCGICYLHSNRIMHRDMKPQNLLINKDGFL----KICDFGLARTF-TIPPRQYTHEVVTLWYRPVELLMNSPLYDISVDVWGT
...   .  .|.|. |.|.|. |.||..|.|||.||.|.||...| .    ||||||||. | . . . .|. ..|.||.. |... .. |. .||.|. 
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCIIAEMISGNPLFPGD----SEIDQLFKIFRVFGTPTEETWPGFTRLPGYQPTFPKFPEQNLAEVLHCNNDLLVDLLKQLLEINPSKRISAMRALQHPF
|||..||..|.|.|||.    . .||...|.|. |.|... ||   . . .  ...   .. . .. |  .. . |..| .|. .|.||..|. .||||.
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

F
|
F
Kinase 95940.m00220.AA S_TKc 6-287 28 2.8e-95 323.74 SMART 1-231 (231) Show / Hide 
Range on Protein: 6-287
Range on HMM: 1-231/231
Sequence Identity: 28% (86 aa)

FTKKEKLGEGTYGVVYRAVDNRTGEIVALKQMRLEQEEEGIPVTALREIALMRNLNHQNIVALKDVISTKGALTMVSEYLEF---DLRKYMDSTRTG---
... .|.|.|..|.||......||.|||.|...          ...|||..... .| ||| |.||. . . | || ||..    ||..|... ...   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--VHPALLKSYAFQLLCGICYLHSNRIMHRDMKPQNLLINKDGFLKICDFGLARTFTIPPRQYTHEVVTLWYRPVELLMNSPLYDI-SVDVWGTGCIIAE
   ..   ..|. |..|.. |.||..|.||| ||.|.|...   .||||||||| .       |. ..|.||.. |.|     |.  ..|.|  |||..|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MISGNPLFPGDSEIDQLFKIFRVFGTPTEETWPGFTRLPGYQPTFPKFPEQNLAEVLHCNNDLLVDLLKQLLEINPSKRISAMRALQ-------HPFF
|..| |.||      |....|.. |                                    . . |.....|. .|.||..|  |||       ||.|
MLCGYPPFP------QMQMMFKKIG-----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 95940.m00220.AA CDK4 6-287 44 1.6e-92 313.64 In-house 1-290 (290) Show / Hide 
Range on Protein: 6-287
Range on HMM: 1-290/290
Sequence Identity: 44% (130 aa)

FTKKEKLGEGTYGVVYRAVDNRTGEIVALKQMRLEQEEE--GIPVTALREIALMRNL---NHQNIVALKDV---ISTKG---ALTMVSEYLEFDLRKYMD
. .   .||| || |||| |  || .||||| |   .||  |.|.  .|||..|| |   .| ||| |.||   . | .    .||| |  . ||. |.|
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

STRT-GVHPALLKSYAFQLLCGICYLHSNRIMHRDMKPQNLLINKDGFLKICDFGLARTFTIPPRQYTHEVVTLWYRPVELLMNSPLYDISVDVWGTGCI
     |. |   |   .||| |. .|||.|| ||| ||||.|.. || .|. ||||||..       |  |||||||  | |  |. |   || |  |||
KCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSF-QMALTPVVVTLWYRAPEVLLQSY-YNTPVDMWSVGCI

IAEMISGNPLFPGDSEIDQLFKIFRVFGTPTEETWPGFTRLPGYQPTFPKFPEQNLAEVLHCNNDLLVDLLKQLLEINPSKRISAMRALQHPFF
.|||    |||.| || ||| ||| | |.|.|. ||    ||     ||    ... ..      .  |||.. |  |..||.|| ..||||.|
FAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVSLP--WDHFPQRHPRPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase 95940.m00220.AA CRK7 6-287 34 4.1e-91 309.02 In-house 1-343 (343) Show / Hide 
Range on Protein: 6-287
Range on HMM: 1-343/343
Sequence Identity: 34% (118 aa)

FTKKEKLGEGTYGVVYRAVDNRTGEIVALKQMRLEQE---EEGIPVTALREIALMRNLNHQNIVALKDVI----------STKGALTMVSEYLEFDLRKY
. . .  |||||| || |....|||.|||| .|.. |   .|| |.|| ||| . | ||||||| ||...          ..||.  || ||   ||   
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

MDST-RTGVHPALLKSYAFQLLCGICYLHSNRIMHRDMKPQNLLINKDGFLKICDFGLARTFTIPP--RQYTHEVVTLWYRPVELLMNSPLY--------
..|       .  .|..  ||| |. |.| . ..||| |  |.|.|  | .|| |||||| .      |.||  |.|||||| |||     |        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------DISVDVWGTGCIIAEMISGNPLFPGDSEIDQLFKIFRVFGTPTEETWPGFTRLPGYQPTFPKF--PEQNL
                                ..|.|..||| .|  .. |.|.|  |..|| ||... |.|. . ||  ..||...   ||       .
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRLR

AEVLH-----CNNDLLVDLLKQLLEINPSKRISAMRALQHPFF
 |. |           .||| ..|  .|.||..|  .|||..|
EEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase 95940.m00220.AA Pkinase_Tyr 6-152 30 3.9e-24 82.35 Pfam 1-160 (270) Show / Hide 
Range on Protein: 6-152
Range on HMM: 1-160/270
Sequence Identity: 30% (51 aa)

FTKKEKLGEGTYGVVYRAVDN----RTGEIVALKQMRLEQEEEGIPVTA------LREIALMRNL-NHQNIVALKDVIS-TKGA--LTMVSEYLEF-DLR
 |. .||||| .|.||... .     |.  || | ..     ||    .      .||...|..| .|.||| |  |..  ..   . .| || .  ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

KYMDST---RTGVHPALLKSYAFQLLCGICYLHSNRIMHRDMKPQNLLINKDGFLKICDFGLART
.|  .    .  . .  | ....|  .|  ||.|... |||    | |...... |||||||||.
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD
Kinase 95940.m00220.AA TyrKc 6-286 22 1.3e-15 29.66 SMART 1-280 (280) Show / Hide 
Range on Protein: 6-286
Range on HMM: 1-280/280
Sequence Identity: 22% (71 aa)

FTKKEKLGEGTYGVVYRAVDNRTGEIVALKQMRLEQEEEGIPVTALREIALMRNL--NHQNIVALKDVISTK-------GALTMVSEYLEF-DLRKYMDS
 |...||||| .|.||... .   . || | .. .          .||. .|..|  .|.|||.|  |....       . | .| || .  ||..|  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

TRTGVHPALLKSYAFQLLCGICYLHSNRIMHRDMKPQNLLINKDGFLKICDFGLARTFTIP------PRQYT-----HEV--VTLWYRPVELLMNSPLYD
.|  . .. | |...|  ||  ||||... |||    | |.....  ||.||||.|  .           |.     ..   . .   . | . |   . 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

ISVDVWGTGCIIAEMIS-GNPLFPG-----DSEIDQLFKIFRVFGTPTEET----WPGFTRLPGYQPTFPKFPEQNLAEVLHCNNDLLVDLLKQLLEINP
.  |||  |  . |. . | .  ||      | .. . .. . .  |  .                     |         .|  ..   . ||  . .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------F--------VCCPDEMYQ-IMKQCWHEDP

SKRISAMRALQHPF
..| . .... . |
EDRPT-FSEIHECF