Gene 96252.m00271 (T.vaginalis)

96252.m00271

Species: T.vaginalis
Alias: TvagK0611, 96252.m00271
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDC2

Sequence

Name Sequence Type Origin Length Description Download
96252.m00271.AA Protein None 267 None Fasta, JSON
96252.m00271.kin_dom Protein Kinase Domain None 260 None Fasta, JSON

Protein domain

Protein domains of 96252.m00271.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 96252.m00271.AA CDK 7-209 38 1.7e-100 322.25 In-house 1-229 (284) Show / Hide 
Range on Protein: 7-209
Range on HMM: 1-229/284
Sequence Identity: 38% (92 aa)

FTNATKIGKGTYGTVYSAIWTSTN-----EVVAIKKMKIES-----SNEGIPCTSLREIAILNNFKHKNIVECKAVMHSK-----------NSIHVVFEY
.    ||| ||||.|| |. . |.     ..||.|| ..|.       ||.|.|..|||..| .  |.|||  . | |.|           |..  ||||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

CRWDLRKFIKKENYSIQYSQVISFTKQLLAGLNFLHMNHIIHRDIKPQNLLITEDLC-----LKLADFGLCRTSNI------PTKKLSSEVITRWYRPPE
. .|| |...          . ....||| ||...| |.|.|||.||||.||... .     ||.||||| |  .|      |......||.|.|||.||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

LIKGSTKYG--CEVDIWSAGCVVAEMLT---GSALFPCDS
|  ||..|.  ...|.||.||. |||.|   . .|||.||
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDS
Kinase 96252.m00271.AA CDC2 7-209 42 8.4e-96 294.91 In-house 1-213 (301) Show / Hide 
Range on Protein: 7-209
Range on HMM: 1-213/301
Sequence Identity: 42% (90 aa)

FTNATKIGKGTYGTVYSAIWTSTNEVVAIKKMKIESSNEG--IPCTSLREIAILNNFK-HKNIVECKAVMHSKNSIHVVFEYCRWDLRKFIK---KENYS
..   |||.|||| || .. . ||..||.|| ..|. .||  .| |..||| .| . | |.|||  . |.|. |..  ||||.  ||.|. .   . |..
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

IQYSQVISFTKQLLAGLNFLHMNHIIHRDIKPQNLLITEDLCLKLADFGLCRTSNIPTKKLS--SEVITRWYRPPELIKGSTKYGCEVDIWSAGCVVAEM
.. . | |...|.| |..|.| . |.|||.||||.|| ..  .|.||||| |. .|| ...    ||.|.|||.||.  |. .| ..||.|| ||. |||
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---LTGSALFPCDS
    |  .||. ||
FMDVTKKPLFHGDS
Kinase 96252.m00271.AA CMGC 7-217 24 2.9e-92 303.42 In-house 1-366 (513) Show / Hide 
Range on Protein: 7-217
Range on HMM: 1-366/513
Sequence Identity: 24% (90 aa)

FTNATKIGKGTYGTVYSAIW--------------TSTNEVVAIKKMKIESSNE----------GIPCTSLREIAILNNFK-----------------HKN
...  |||.||||.||...               . |||.|||||.| .  .|          |.|...|||| || ...                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVECKAVMHSKN-----------------SIHVVFEYCRWDLRKFIKKENY--------SIQYSQ------------VISFT------KQLLAGLN--FL
|| .. . ..||                 ... ||||. .|| ..||. .              .            . .|.      .|.| ||.  ..
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HMNH--IIHRDIKPQNLLITED--------------------LCLKLADFGLCRTSNIP---------------------TKKLSSEVITRWYRPPELIK
| .   |||||.||.|.||...                     .||..||||.|  ...                     .. ....| |||||.||.. 
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GS---------TKYGCEVDIWSAGCVVAEMLTG--------SALFPCDSN-----------EEMLNEI
|.         ..|....|.||.||. |||.||          ||| .|.            ..|..|
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKI
Kinase 96252.m00271.AA S_TKc 7-266 29 2.5e-91 310.66 SMART 1-231 (231) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-231/231
Sequence Identity: 29% (82 aa)

FTNATKIGKGTYGTVYSAIWTSTNEVVAIKKMKIESSNEGIPCTSLREIAILNNFKHKNIVECKAVMHSKNSIHVVFEYCRW---DLRKFIKKENYS---
..   |||||..|.|| .....|...||||..|         .. .|||.|| . .|.||| .. |... .....|.|||     ||...||| ..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--IQYSQVISFTKQLLAGLNFLHMNHIIHRDIKPQNLLITEDLCLKLADFGLCRTSNIPTKKLSSEVITRWYRPPELIKGSTKYGC-EVDIWSAGCVVAE
  .   .. ....|.. .|...| ..|||||.||.|.|..|  ..|..||||.|         .. . |.||..||..    .||. ..|.|| ||...|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MLTGSALFPCDSNEEMLNEIEFTLKNDFQILYQKLNHCDNGMFELITRMLDQNPATRITASEALR-------HRAL
||.|  .||    ..|.. |                  .  . ..| ..|. .|. |.|| |||.       |  .
MLCGYPPFP--QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 96252.m00271.AA CDK5 7-217 47 6.9e-90 284.17 In-house 1-212 (287) Show / Hide 
Range on Protein: 7-217
Range on HMM: 1-212/287
Sequence Identity: 47% (100 aa)

FTNATKIGKGTYGTVYSAIWTSTNEVVAIKKMKIESSNEGIPCTSLREIAILNNFKHKNIVECKAVMHSKNSIHVVFEYCRWDLRKFIKKENYSIQYSQV
.    ||| ||||||| |    | |.||.|. ...|  ||.|.| .|||..|   ||||||    |.|| . .  |||.|  ||.|.. . |  ..   .
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

ISFTKQLLAGLNFLHMNHIIHRDIKPQNLLITEDLCLKLADFGLCRTSNIPTKKLSSEVITRWYRPPELIKGSTKYGCEVDIWSAGCVVAEML-TGSALF
 ||  ||| || | | .|. ||| |||||||     |||||||| | . || .  |.||.| |||||    || .|   .|.||.||. |||  .|  ||
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

PCDSNEEMLNEI
|  . |. |  |
PGNDVEDQLKRI
Kinase 96252.m00271.AA Pkinase 7-266 27 7.7e-82 282.99 Pfam 1-293 (293) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-293/293
Sequence Identity: 27% (80 aa)

FTNATKIGKGTYGTVYSAIWTSTNEVVAIKKMKIESSNEGIPCTSLR--EIAILNNFKHKNIVECKAVMHSKNSIHVVFEYCRW-----DLRKFIK-KEN
..   |||.|..|.|| ... .|...||.|..| .. ... . | .|  ||.|.....|.|||... ....|..|..|.|||.      ||  .|. ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

YSI--QYSQVISFTKQLLAGLNFLHMNHIIHRDIKPQNLLITEDLCL----KLADFGLCRTS-NIPTKKLSSEVITRWYRPPELIKGSTKYGCEVDIWSA
 ..  .. ..... .|.| ||...| . |||||.||.|.|| ..  .    |..||||..   . .   ... . |.||..||.|.|...|| .||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCVVAEMLTGSALFPCD----SNEEMLNEIEFTLKNDFQILYQKLNHCD-----------------NGMFELITRMLDQNPATRITASEALRHRAL
||...|||.|  .|| .    .  ...  |. ... ..   .....                      . ..|...|...|. |.|| ..| |  .
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 96252.m00271.AA CDK7 7-199 39 7.8e-80 212.19 In-house 1-197 (288) Show / Hide 
Range on Protein: 7-199
Range on HMM: 1-197/288
Sequence Identity: 39% (77 aa)

FTNATKIGKGTYGTVYSAIWTSTNEVVAIKKMK----IESSNEGIPCTSLREIAILNNFKHKNIVECKAVMHSKNSIHVVFEYCRWDLRKFIKKENYSIQ
..   .|| |...||| |  ..|...||||| |     .    ||  | .||| ||   .| |...   ..  | .|  ||..  |||   ||       
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

YSQVISFTKQLLAGLNFLHMNHIIHRDIKPQNLLITEDLCLKLADFGLCRTSNIPTKKLSSEVITRWYRPPELIKGSTKYGCEVDIWSAGCVVAEML
 . . ......| || ..| | | |||.|| |||. |.  ||.||||| |    | . ... |.||||| |||  |   ||  ||.|| ||. || .
PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELM
Kinase 96252.m00271.AA PFTAIRE 7-206 41 7.5e-69 235.05 In-house 1-199 (287) Show / Hide 
Range on Protein: 7-206
Range on HMM: 1-199/287
Sequence Identity: 41% (83 aa)

FTNATKIGKGTYGTVYSAIWTSTNEVVAIKKMKIESSNEGIPCTSLREIAILNNFKHKNIVECKAVMHSKNSIHVVFEYCRWDLRKFIKKENYSIQYSQV
. .  | | |.| ||| .|   .. .|| |  ...  .|| |.|  ||   | | || |||    . | |     ||||   || ... | .  ..   |
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQ-QEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGMHPNNV

ISFTKQLLAGLNFLHMNHIIHRDIKPQNLLITEDLCLKLADFGLCRTSNIPTKKLSSEVITRWYRPPELIKGSTKYGCEVDIWSAGCVVAEMLTGSALFP
  |  ||| || . |  .. |||.|||||||..   |||||||| |   .|..  |.||.| |||||    ||| |  ..|.| .||.  ||..| ..||
RLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAFP
Kinase 96252.m00271.AA PCTAIRE 7-206 44 6.9e-65 221.89 In-house 1-199 (291) Show / Hide 
Range on Protein: 7-206
Range on HMM: 1-199/291
Sequence Identity: 44% (89 aa)

FTNATKIGKGTYGTVYSAIWTSTNEVVAIKKMKIESSNEGIPCTSLREIAILNNFKHKNIVECKAVMHSKNSIHVVFEYCRWDLRKFIKKENYSIQYSQV
..   | | ||| |||      |. .|| |  . |   || |||  ||.  | . || |||    ..|   .   ||||   ||....    . ..   |
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLE-HEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTHHQLTLVFEYMDMDLKQYMDDCGNIMNMHNV

ISFTKQLLAGLNFLHMNHIIHRDIKPQNLLITEDLCLKLADFGLCRTSNIPTKKLSSEVITRWYRPPELIKGSTKYGCEVDIWSAGCVVAEMLTGSALFP
  |  ||| || . |   | ||| ||||||| |.  |||||||| |   .|||  | ||.| |||||. . ||| |  ..|.|  ||. .|| || .|||
KLFLFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGRPLFP
Kinase 96252.m00271.AA PITSLRE 7-217 39 3.9e-63 216.07 In-house 1-219 (295) Show / Hide 
Range on Protein: 7-217
Range on HMM: 1-219/295
Sequence Identity: 39% (86 aa)

FTNATKIGKGTYGTVYSAIWTSTNEVVAIKKMKIE--SSNEGIPCTSLREIA-ILNNFKHKNIVECKAVM--HSKNSIHVVFEYCRWDLRKFIKKEN---
|    .|. |||| || |  . |.|.||.|..|.|     ||.| ||||||  ||   .| |||  | .     ...|  |.||   ||.  . . .   
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

YSIQYSQVISFTKQLLAGLNFLHMNHIIHRDIKPQNLLITEDLCLKLADFGLCRTSNIPTKKLSSEVITRWYRPPELIKGSTKYGCEVDIWSAGCVVAEM
 . . ... ... ||| |  ..| | |.||| |  |||..   .||..|||| |    | |.... |.| ||| |||  |. ||   ||.|| ||. ||.
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF

LTGSALFPCDSNEEMLNEI
.|.  ||. .|  . .| |
ITMKPLFQGKSEIDQINCI
Kinase 96252.m00271.AA CDK10 7-217 37 1.1e-61 211.22 In-house 1-213 (285) Show / Hide 
Range on Protein: 7-217
Range on HMM: 1-213/285
Sequence Identity: 37% (80 aa)

FTNATKIGKGTYGTVYSAIWTSTNEVVAIKKMKIESSNEGIPCTSLREIAILNNFKHKNIVECKAVM--HSKNSIHVVFEYCRWDLRKFIKKENYSIQYS
|    ..| |||| || |  . ..|.||.||....   .|.|  .|||| .| . .|.|||| . |.  .. .|| .| .||  ||   .         .
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDNMPQPFTET

QVISFTKQLLAGLNFLHMNHIIHRDIKPQNLLITEDLCLKLADFGLCRTSNIPTKKLSSEVITRWYRPPELIKGSTKYGCEVDIWSAGCVVAEMLTGSAL
||   . |.| || .|| | .||||.|  |||.|.. |.|.||||| |   .| | .   ..| ||| |||. |...    .|.| .||...|.| .  |
QVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLVHKPL

FPCDSNEEMLNEI
.|  |    .. |
MPGNSEIHQIDMI
Kinase 96252.m00271.AA CDKL 7-209 39 8.8e-60 203.06 In-house 1-204 (286) Show / Hide 
Range on Protein: 7-209
Range on HMM: 1-204/286
Sequence Identity: 39% (81 aa)

FTNATKIGKGTYGTVYSAIWTSTNEVVAIKKMKIESSNEGIPCTSLREIAILNNFKHKNIVECKAVMHSKNSIHVVFEYCRWDLRKFIKKENYSIQYSQV
. .  |.| | ||.|.      |...||||| |    .. .  . .||| .| ..||.|||. . |   |. .| |||||   .    ..    . ...|
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLKHENIVNLIEVFRRKRKLHLVFEYCDHTVLHELEEYPNGVDEHVV

ISFTKQLLAGLNFLHMNHIIHRDIKPQNLLIT-EDLCLKLADFGLCRTSNIPTKKLSSEVITRWYRPPELIKGSTKYGCEVDIWSAGCVVAEMLTGSALF
 . . |.| ..||.| . .||||||| |.|||  .  .|| |||. |. . |.  .   | ||||| |||  | |.|| .||||..|||.|||..| .|.
RKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFARMLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPLW

PCDS
| .|
PGQS
Kinase 96252.m00271.AA Pkinase_Tyr 7-200 26 3.3e-29 99.53 Pfam 1-209 (270) Show / Hide 
Range on Protein: 7-200
Range on HMM: 1-209/270
Sequence Identity: 26% (58 aa)

FTNATKIGKGTYGTVYSAIWT----STNEVVAIKKMKIESSNEGIPCTS------LREIAILNNF-KHKNIVECKAVMH-SKNS--IHVVFEYCRW-DLR
 |   |.|.| .|.|| ..|.    .|.  ||.|..|     ||           .||..|. .. .|.||| . .|    . .  | .|.||.   ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

KFIKKE---NYSIQYSQVISFTKQLLAGLNFLHMNHIIHRDIKPQNLLITEDLCLKLADFGLCRTS-----NIPTKKLSSEVITRWYRPPELIKGSTKYG
.. .|    . ..  .. ...  |  .|...|. ...||||.   | |.||... | .||||.|.         .|. .. .  .|. .|| |. .  . 
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWM-APECINYGK-FT

CEVDIWSAGCVVAEMLT
 . |.|| | .  |..|
TKSDVWSFGVLMWEIFT
Kinase 96252.m00271.AA TyrKc 7-266 23 3.7e-28 100.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-280/280
Sequence Identity: 23% (71 aa)

FTNATKIGKGTYGTVYSAIWTSTNEVVAIKKMKIESSNEGIPCTSLREIAILNNF--KHKNIVECKAVMHSK-------NSIHVVFEYCRW-DLRKFIKK
 |   |.| | .|.|| ..|.   . ||.|..| ..  | .    .||. |. ..  .|.||| . .|  ..         . .|.||. . ||.....|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDF----MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

ENYSIQYSQVISFTKQLLAGLNFLHMNHIIHRDIKPQNLLITEDLCLKLADFGLCRTSNIP--------TKKL----SSE--VITRWYRPPELIKGSTKY
    .. .. .||  |  .| ..|| ...||||.   | |..|... | .||||.|             ...     ..   .  ||. .|| |    |.
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NYGKF

GCEVDIWSAGCVVAEMLTGSALFPCD------SNEEMLNEIEFTLKNDFQILYQKLN-------HCDNGMFELITRMLDQNPATRITASEALRHRAL
  . |.|| | .  |..|  .  . .      ||.|... ..     .   . |  |       .|   |......  . .|. | | ||   |. .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVK-----QGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 96252.m00271.AA CDC2 218-266 27 4.4e-09 23.5 In-house 248-301 (301) Show / Hide 
Range on Protein: 218-266
Range on HMM: 248-301/301
Sequence Identity: 27% (15 aa)

EFTLKNDFQILYQ---KLNH--CDNGMFELITRMLDQNPATRITASEALRHRAL
... ..  .|...   |.|   .|.  ..|. .||  .|. ||.| |||.|. .
RWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase 96252.m00271.AA CMGC 222-266 18 2.9e-07 18.93 In-house 437-513 (513) Show / Hide 
Range on Protein: 222-266
Range on HMM: 437-513/513
Sequence Identity: 18% (14 aa)

KNDFQILYQKLNH--------------------------------CDNGMFELITRMLDQNPATRITASEALRHRAL
..... |. ...                                 ||   ..|. .||  .|. ||||..||.|  .
PKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 96252.m00271.AA CDK5 241-266 42 3e-06 15.03 In-house 262-287 (287) Show / Hide 
Range on Protein: 241-266
Range on HMM: 262-287/287
Sequence Identity: 42% (11 aa)

ELITRMLDQNPATRITASEALRHRAL
.|  .||  ||. ||.| .||.|   
DLLQKMLQCNPNQRISAKAALHHPYF
Kinase 96252.m00271.AA CDK 241-266 38 8e-06 14.46 In-house 259-284 (284) Show / Hide 
Range on Protein: 241-266
Range on HMM: 259-284/284
Sequence Identity: 38% (10 aa)

ELITRMLDQNPATRITASEALRHRAL
.|. .||  .|. ||.|..|| |  .
DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 96252.m00271.AA CDK7 241-266 26 1.2e-05 10.58 In-house 263-288 (288) Show / Hide 
Range on Protein: 241-266
Range on HMM: 263-288/288
Sequence Identity: 26% (7 aa)

ELITRMLDQNPATRITASEALRHRAL
.|. .|.  || .|.|....| .   
DLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase 96252.m00271.AA PITSLRE 240-263 58 2.6e-05 15.56 In-house 269-292 (295) Show / Hide 
Range on Protein: 240-263
Range on HMM: 269-292/295
Sequence Identity: 58% (14 aa)

FELITRMLDQNPATRITASEALRH
|.|  .||  ||. |||||.|| |
FDLLNQMLTYNPKNRITASDALKH
Kinase 96252.m00271.AA PFTAIRE 228-266 24 4.9e-05 13.67 In-house 247-287 (287) Show / Hide 
Range on Protein: 228-266
Range on HMM: 247-287/287
Sequence Identity: 24% (10 aa)

LYQKLNHCD--NGMFELITRMLDQNPATRITASEALRHRAL
| . ..  .  .. ..|.. ||  .|  |. | ||. |  .
LCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase 96252.m00271.AA CDKL 246-266 23 0.00287 7.03 In-house 266-286 (286) Show / Hide 
Range on Protein: 246-266
Range on HMM: 266-286/286
Sequence Identity: 23% (5 aa)

MLDQNPATRITASEALRHRAL
.|. .|. |.|......|   
CLHMDPDERMTCEQLMHHPYF
Kinase 96252.m00271.AA PCTAIRE 241-266 26 0.011099 5.18 In-house 266-291 (291) Show / Hide 
Range on Protein: 241-266
Range on HMM: 266-291/291
Sequence Identity: 26% (7 aa)

ELITRMLDQNPATRITASEALRHRAL
.|.| .|   .  |. | .|..|   
DLLTMLLQYESKNRVSAEKAMKHPYF