Gene 92799.m00046 (T.vaginalis)

92799.m00046

Species: T.vaginalis
Alias: TvagK1021, 92799.m00046
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
92799.m00046.AA Protein None 475 None Fasta, JSON
92799.m00046.kin_dom Protein Kinase Domain None 216 None Fasta, JSON

Protein domain

Protein domains of 92799.m00046.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 92799.m00046.AA S_TKc 8-243 25 1.3e-50 175.38 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-243
Range on HMM: 1-231/231
Sequence Identity: 25% (66 aa)

FTQLERLGDGSFGRVELLQREDDGVLFAVKVFETPAAITTAEKEIDLMNLVSSPFIVKLYDVYRTPESVGILMDPCLG--GSLRLKIASKSPSNP---FT
.. |. .| |.||.| . .  ..| ..|.|.        ....||...     |.|||||||... ... . |. | |  |.|.  | .. .  .   |.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

FNEIIEITTQLLLALKEIHKNGYAHRDLSPSNILFCKEKSNRIQLIDFGVSEYVGKGEARGTAGTPNYMSLEMKKGLPHNQ-MTDMYSLGLIIFEMCELR
  ..  .. |...||. .|..|  |||| |.|||...    .| ..|||..  .     .   |||.||. |.    ...    |..|.| |..||.  .
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

LPRPGETTSE------SQPSLGALIENLLSEDPSSRPNVEDCLS-------FPDV
 | |  .  .      |.. .  .|...|  ||. || . ..|         | .
PPFP--QMQMMFKKIGSPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 92799.m00046.AA Ciliate-E2 8-238 19 6.9e-42 141.56 In-house 1-360 (365) Show / Hide 
Range on Protein: 8-238
Range on HMM: 1-360/365
Sequence Identity: 19% (72 aa)

FTQLERLGDGSFGRVELLQREDDGVLFA----------------VKVFE------TPAAITTAEKEIDLMN----------------LVSSPFIVKLYDV
.  .. .| |.|| | . ..  .. .||                ||...       .  |   ..||..|.                ....|.|.|.|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YR--TPESVGILMDPCLGGSLRLKIA---SKSPSN-----PFTFNEIIEITTQLLL---------------ALKEIHKNG-YAHRDLSPSNILFCKEKSN
.   . ... . |. | ||.|.  |     |....     .|| .||..|..|.|                ||...|...   |||. |.||||      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

RIQLIDFGVSEYVGKGEARGT---------------------------------AGTPNYMSLEMKKGLP---------HNQMTDMYSLGLIIFEMCELR
 | .|||| | .. . . ..|                                 .|||.||. |. .| .         .. . |..||| |..||.  .
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

LPRPGETTSES-QPSLG--------------------------ALIEN----LLSEDPSSRPN-VEDCL
.|   .   .  . ..                            || .    .|  ||. |..  |..|
PPF--QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQIL
Pkinase 92799.m00046.AA Pkinase 8-243 23 4.4e-41 146.36 Pfam 1-293 (293) Show / Hide 
Range on Protein: 8-243
Range on HMM: 1-293/293
Sequence Identity: 23% (70 aa)

FTQLERLGDGSFGRVELLQREDDGVLFAVKVFETPAAITTAEK------EIDLMNLVSSPFIVKLYDVYRTPESVGILMDPCLGG----SLR----LKIA
.. ....| ||||.| . .. ..| ..|||... . .    ..      || .|. ...|.||.|||..... .. . |. | ||    .|         
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

SKSPSNPF--TFNEIIEITTQLLLALKEIHKNGYAHRDLSPSNILFCKEKSNR---IQLIDFGVSE---YVGKGEARGTAGTPNYMSLEMKK-GLPHNQM
  . ...|  . .|.. . .|.| .|. .|..|  |||| |.|||.  .. .    . ..|||...   |  .. . . .|||.||. |  . | .. . 
--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

TDMYSLGLIIFEMCELRLPRPGE-----------TTSESQ-------------------------------PSLGALIENLLSEDPSSRPNVEDCLSFPD
 ||.|.|.|..||.  |.| ||.                .                               ...  .|...|  ||..||. |..|  | 
VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

V
.
F
Kinase 92799.m00046.AA AGC 8-197 18 2e-40 101.0 In-house 1-298 (395) Show / Hide 
Range on Protein: 8-197
Range on HMM: 1-298/395
Sequence Identity: 18% (56 aa)

FTQLERLGDGSFGRVELLQRE------DDGVLFAVKVFETPA--------AITTAEKE------------IDLMNLVS----------SPFIVK-LYDVY
|  |  .| ||||.| | ..       | | ..|.|| .            .  .  |             . . ...          .||||| |.  .
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

RTPES--VGILMDPCL--------GGSLRLKIASKS--PSNPFTFNEIIEITTQ-------LLLALKEIHK-NGYAHRD-LSPSNILFCKEKSNRIQLID
 ...   . ..|. .         || . | .  .    .  |. ...  .. .       ..|||  .|. .|. ||| | | |||. ..    | | |
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED--GHIKLTD

FGVSEYVGKGE----------------------------------------------------ARGTAG--TPNYMSLEMKKGLPHNQMTDMYS--LGLI
|| .  . ...                                                    .    |  ||.||. |.     ...  | .|  || .
FGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCL

IFEM
..||
MYEM
Kinase 92799.m00046.AA STE 8-243 18 8.3e-40 138.26 In-house 1-359 (359) Show / Hide 
Range on Protein: 8-243
Range on HMM: 1-359/359
Sequence Identity: 18% (69 aa)

FTQLERLGDGSFGRVELLQRED---------------DGVLFAVKVFETPAA-------------------ITTAEKEIDLMNLVS--SPFIVKLYDVYR
.. .|..| |.|| | .  . .                |...|.|. .                       .   .|||..|.  .  .|.||| |. | 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TP-------ESVGILMDPCLGGSLRLKIASK-SPSNPFT----------FNEIIEITTQLLLA-LKEIHKNGYAHRDLSPSNILFCKEKSNRIQLIDFGV
         ... | |  . ||||.  | .| .. .|..           ..|. |. |.| . |. .|.... |||. |.|||.       . |.||||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-------VKLCDFGV

SEYVGK------------------GEARGTAGTPNYMSLEMKKG------LPHNQMTDMYSLGLIIFEMCELRLP----RPG----ETTSE---------
.  . .                  ..    .||| .|. |. ..       ...   |..|||. | ||.. . |     |     ... .         
CGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----------SQ----------------------PSLGALIENLLSEDPSSRPNVEDCLS--FPDV
            .                      |..   |.. |  ||. ||.... |.   | .
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 92799.m00046.AA CAMK 13-197 19 1.4e-33 105.04 In-house 1-327 (425) Show / Hide 
Range on Protein: 13-197
Range on HMM: 1-327/425
Sequence Identity: 19% (63 aa)

RLGDGSFGRVELLQREDDG------------VLFAVKVFE------------------------------TPAAITTAEKEIDLMNL-------VSSPFI
 || |||| | | ..  ..            . .|.|. .                              .|      ..||..|..       .. | |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLYDVYR------------TPES--------VGILM---DPCLGG----SLRLKIASKSP------------SNPFTFNEIIEITTQLLLALKEIHKNG
.|||.||             | .         . . |   . | ||     |  .| ....            .  ||  |   .  |.. |.. .|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

YAHRDLSPSNILFCKEKS---------------NRIQLIDFGVSEYVGKGE-------------------------ARGTAGTPNYMS-LEMKKG-----
 .|||| | |||... ..               | | .|||| . .. .||                          .   ||| ||.  |. .|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------LPHNQMTDMYSLGLIIFEM
          .... .|| |.| | . |
MQNATDEEKPYYGPKCDMWSCGVILYIM
Kinase 92799.m00046.AA Ciliate-E2a 8-211 32 2.3e-32 92.58 In-house 1-223 (275) Show / Hide 
Range on Protein: 8-211
Range on HMM: 1-223/275
Sequence Identity: 32% (73 aa)

FTQLERLGDGSFGRVELLQREDDGVLFAVKVFETPAAITTA------EKEIDLMNLVSSPFIVKLYDVYRTPESVGILMDPCLGGSLRLKIASKSPSNPF
.  .  .| |.||.|.| |. ..|  ||.|.|.  ..  .       ..||..|  .. | | |||.|| .  .  . |. | ||.|  ||  .   . |
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCK--RFF

TF-NEIIEITTQLL-LALKEIHKNGYAHRDLSPSNILF--CKEKS---NRIQLIDFGVSEYVGKGE---ARGTAGTPNYMS---LEMKKGLPH---NQMT
.. .|| .|  |||  .|  .|.... |||| | ||||  |. .|     | .|||| .... | |        ||| |.    | .|  | |    .  
EEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKC

DMYSLGLIIFEMCELRLPRPGETTSE
|| |.|.|.. ..  ..| .|.|..|
DMWSCGVIFYILLCGKPPFKGKTYNE
Kinase 92799.m00046.AA Ciliate-E2-Unclassified 8-198 20 1.9e-31 106.37 In-house 1-264 (352) Show / Hide 
Range on Protein: 8-198
Range on HMM: 1-264/352
Sequence Identity: 20% (54 aa)

FTQLERLGDGSFGRVELLQREDDGVLF------------AVKVFETP---AAITTAEKEIDLMNLVS--------------SPFIVKLYDVYRTPESVGI
.. .. .| |.|| | ..|..... ..            ..|  ..      . ......   . ..              .|||||.... .. . . |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

LMDPCLGGSLRLKIASKSP--------------SNPFTFNEII-----EITTQLLLALKEIHKNG-YAHRDLSPSNILFCKEKS-NRIQLIDFGVSEYVG
 |. | ||.|.  | ...               .. || ....      .. |.|..|. .|...   |||. |.|||| .... ..| .|||| | . .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

-----------------KGEARGTAGTPNYM----SLEMKKGLPHN----QMTDMYSLGLIIFEMC
                 . ..  ..||||||    . |. .|  ..     . |..||| |..||.
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEML
Kinase 92799.m00046.AA ULK 8-197 23 3.9e-29 98.88 In-house 1-249 (329) Show / Hide 
Range on Protein: 8-197
Range on HMM: 1-249/329
Sequence Identity: 23% (59 aa)

FTQLERLGDGSFGRVELLQREDD----GVLFAVKVFETPAAITTA------------EKEIDLMNLVS----SPF----IVKLYDVYRTPES--VGILMD
.   ..|| ||||.|     ...    ....|.|. .    .               ..||..|        ...    ||||||...|. .  . | |.
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

PCLGGSLRLKIASKSPS-----NPFTFN--EIIEITTQLLLALKEIHKNGYAHRDLSPSNILFCKEK----------SNRIQLIDFGVSEYVGKG-----
 | || |.  |  . ..     .. ...  |.|..  |.| ..||.||... |||. |.|||  . .          .... . ||| .  | ..     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

EARGTA------GTPNYMSLEMKKGL----PHN-QMTDMYSLGLIIFEM
 .  .       ||| ||. .  .|.    |..   .|..||| |..||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEM
Kinase 92799.m00046.AA ULK 8-203 23 7.7e-27 92.3 In-house 1-251 (324) Show / Hide 
Range on Protein: 8-203
Range on HMM: 1-251/324
Sequence Identity: 23% (60 aa)

FTQLERLGDGSFG-RVELLQREDD---GVLFAVKVFE------TPAA------ITTAEKEIDLMNLVS---SPF--IVKLYDVYRTPES--VGILMDPCL
.   ..|| ||||  |     ...   ....|.|. .       .        .   ..|| .|       .|.  ||||||...|. .  . | |. | 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGSLRLKIASKSPS----NPFTFN--EIIEITTQLLLALKEIHKNGYAHRDLSPSNILFCKEK----------SNRIQLIDFGVSEYVGKGEARGTA---
|| |.  |  . ..    .. ...  |.|..  |.. ..||.||... |||. |.|||  . .          .... . ||| .  | ...   .    
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GTPNYMSLEMKKGL----PHN-QMTDMYSLGLIIFEMCELRLP
        ||| ||. .  .|.    |..   .|..||| |..||   . |
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYP
Kinase 92799.m00046.AA RSK 9-197 25 2.5e-25 89.72 In-house 1-205 (278) Show / Hide 
Range on Protein: 9-197
Range on HMM: 1-205/278
Sequence Identity: 25% (53 aa)

TQLE-RLGDGSFGRVELLQREDDGVLFAVKVFETPAAITTAE------KEIDLMNLVS-SPFIVKLYDVYRTPESVGILMDPCLGGSLRLKIASKSPSNP
 ..  ..| |..  .   ...| | ..|.|| .   .....       .|.. . ..  .||||.|.....|.. . . |. | || |  ..  .     
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FTFNEIIEITTQLLLALKEIHKNGYAHRDLSPSNILFCKEKSN--RIQLIDFGVSEY-VGK--GEARGTAGTPNYMSLEMKK---GLP-HNQMTDMYSLG
|. .|  ..  .. ||.. .|. |  |||| |.|||.  |. |  .| |.||| . . . .  . .    .| .||  || |   .   |..  | .|||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

LIIFEM
 ...||
VLMYEM
Kinase 92799.m00046.AA NEK 8-203 28 2.5e-23 79.28 In-house 1-225 (286) Show / Hide 
Range on Protein: 8-203
Range on HMM: 1-225/286
Sequence Identity: 28% (65 aa)

FTQLERLGDGSFGRVELLQREDDGVL-----FAVKVFETP----AAITTAE-KEIDLMNLVSSPFIVKLYDVYRTPE--SVGILMDPCL-GGSLRLK---
.. .. .| ||||.| . .|  ||       .. |   .          |  .|. .     .| ||| || .   .  .  | |. |  || |  |   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IASKS-PSNPFTFNEIIEITTQLLLALKEIHKN-----GYAHRDLSPSNILFCKEKS--NRIQLIDFGVSEYVGKGE---ARG-TAGTPNYMSLEMKKGL
|  .     .|  ..| .. .|..||||..|..        |||. |.||   |. .  . . . |||.|  | . .   |.    ||| ||| |. .. 
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGIS-KVLNHTTDMAYTTQVGTPYYMSPEVCQNK

PHNQMTDMYSLGLIIFEMCEL--RLP
| |.  |. ||| ...||| |  . |
PYNNKSDIWSLGCVLYEMCTLKPKHP
Kinase 92799.m00046.AA TyrKc 8-247 17 1.4e-09 -67.83 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-247
Range on HMM: 1-280/280
Sequence Identity: 17% (52 aa)

FTQLERLGDGSFGRVELLQREDDGVLFAVKVFETPAAITTAEKEIDLMNLV--SSPFIVKLYDVYRTP-------ESVGILMDPCLGGSLRLKIASKSPS
 | .. || | ||.| . .     .  |||.    | .    .|. .|  .  . | ||.|| | ...       | . |.|  . .|.|.  . .. | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

NPFTFNEIIEITTQLLLALKEIHKNGYAHRDLSPSNILFCKEKSNRIQLIDFGVSEYVGKG------EARGTA----GTP-----NYMSLEMKKGLPHNQ
  ..  . ... .|       .|.... ||||   |.|  ...  ..   ||| | ... .      .   ..    |.        |..|  .    . 
--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

MTDMYSLGLIIFEMCEL-RLPRPG---------------------ETTSE--------SQPSLGALIENLLSEDPSSRPNVEDCLSFPDVVDIL
 .| .| |  ..|.. .   | ||                     .   .          . .  ...    |||..||. ...      ....
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------HECF
Kinase 92799.m00046.AA NEK 219-243 36 0.001855 8.5 In-house 262-286 (286) Show / Hide 
Range on Protein: 219-243
Range on HMM: 262-286/286
Sequence Identity: 36% (9 aa)

LIENLLSEDPSSRPNVEDCLSFPDV
||...|  ||..||.... |..| .
LISQMLQKDPEQRPSCNQILEMPFI
Kinase 92799.m00046.AA CAMK 219-243 40 0.003538 5.29 In-house 401-425 (425) Show / Hide 
Range on Protein: 219-243
Range on HMM: 401-425/425
Sequence Identity: 40% (10 aa)

LIENLLSEDPSSRPNVEDCLSFPDV
|| ..|  ||. |...|.||. | .
LIRKMLQVDPEKRMTIEQCLNHPWM