Gene 87283.m00138 (T.vaginalis)

87283.m00138

Species: T.vaginalis
Alias: TvagK0296, 87283.m00138
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
87283.m00138.AA Protein None 1114 None Fasta, JSON
87283.m00138.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 87283.m00138.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 87283.m00138.AA MLK 165-415 31 9.7e-73 247.97 In-house 1-291 (291) Show / Hide 
Range on Protein: 165-415
Range on HMM: 1-291/291
Sequence Identity: 31% (91 aa)

FVIKKKIGSGGFADVHEGIQQSTQ---KVVAIKILHSTEMSETVFT-----SFKREIEIQASLSNFA----ILELVGVCLEA-P-FYIATEFMPKDCLFK
. ....||||.| .|. |  . .    |.||.|. ...   . . |      |..|... . ||       | ...||||.  . |.| .|.... .|. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

RLHLQSK--------------LKPTQRTIIALGCAIGLAYMHKHN---YIHRDIKSLNILLDA------DDFPKICDFGMSRTLAKSKELMSGGVGTAQW
 || ...               .. .   .|| || |..| |..    .||||.|| |||.|.      ..  |||||| || . .... | .  ||. |
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

EAPEVI---NNMQYNEKADVYSYGILLWEILTSDFPFR-GLSQVQVAMNVVGNAIRPVIPNVAPPKITKMIKLCWDQEASRRPSMEQVARAI
 |||||    . .|.||.||.|.|..|||.||   |.. .... ..|. |. | .|| ||. .|. . |..| ||.|....|||. |.    
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 87283.m00138.AA TKL 171-415 24 2.5e-72 246.62 In-house 1-364 (364) Show / Hide 
Range on Protein: 171-415
Range on HMM: 1-364/364
Sequence Identity: 24% (92 aa)

IGSGGFADVHEGIQQSTQ--------KVVAIKILHSTE-------------------------MSETVFTSFKREIEIQASLSNFAILELVGVCLEAP--
||||||. |. |. . .         |.||.|...|..                         ...  .  ...|| .  .|.   |. ..|.|.. |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FYIATEFMPKDCLFKRLHLQSKLKPTQRTIIALGCAIGLAYMHKHN--------YIHRDIKSLNILLDAD--------------DFPK
            ..| .|..|. .|. .||      . ||  .||..| |..|.| .|         ||||.|| |||.| .              ...|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

ICDFGMSRTLAKSKE-------------------LMSGGVGTAQWEAPEVINNM----------------QYNEKADVYSYGILLWEILTSDFPFR--GL
||||| ||.. .|..                     .  .|| .| ||||....                .|.||.||||.||.||||||   |..  . 
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

SQVQVA-------MNVVGNAIRPVIP------------NVAPPKITKMIKLCWDQEASRRPSMEQVARAI
......       | |. .  || ||            . .|| . | .. |||.... |||....   .
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 87283.m00138.AA Dicty4 165-411 34 2.7e-65 216.79 In-house 1-269 (277) Show / Hide 
Range on Protein: 165-411
Range on HMM: 1-269/277
Sequence Identity: 34% (93 aa)

FVIKKKIGSGGFADVHEGIQQSTQKVVAIKIL--HSTEMSETVFTSFKREIEIQASLSNFAILELVGVCL---EAP--FYIATEFMPKDCLFKRLHL---
 .| ..||.|.|. |. |.    .| ||.|.|  | .  .|   ..|..|..| .....  |. . | |.    .|  . | ||.|||  |.. ||    
INIEQRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

---QSKLKP-TQRTI---IALGCAIGLAYMHKHN--YIHRDIKSLNILLDADDFPKICDFGMSR--TLAKSKEL-MSGGVGTAQWEAPEVINNMQYNEKA
   ||. .. . ..    .|. .| |... |  |   ||||.|| |.| |..   |.|||| |.     ...   ... .||. |.||||  .  |||||
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSYGILLWEILTSDFPFR--GLSQVQVAMNVVGNAIRPVIPNVAPPKITKMIKLCWDQEASRRPSMEQV
||||.||.|||||| . |.   . . .|..  |.    || ||.  ||.... |. ||| . ..|||.|..
DVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEI
Kinase 87283.m00138.AA Dicty4-Unclassified 165-415 33 3.9e-58 197.69 In-house 1-263 (263) Show / Hide 
Range on Protein: 165-415
Range on HMM: 1-263/263
Sequence Identity: 33% (89 aa)

FVIKKKIGSGGFADVHEGIQQSTQKVVAIKILHSTEMSET--VFTSFKREIEIQASLSNFAILELVGVCLEAP------FYIATEFMPKDCLFKRLH---
  | . || | |. || |.     | ||.|.. .   .    .   ||.|.||  |..    . . | |. .|      . | .|||.|  ||   |   
IQIDQFIGKGHFSKVHKGNWKG--KDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCI-NPRSHKSTMCIVMEFMHKGNLFEVIHSKP

---LQS-KLKPTQRTIIALGCAIGLAYMHKHNYIHRDIKSLNILLDADDFPKICDFGMSRTLAKSKELMSGGVG-TAQWEAPEVINNMQYNEKADVYSYG
    |. ||  |    .|.  | |....|  | ||||||| |||.| .   || |||.||       .    .. |  ||.||.     || |.|||||.
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTT--IAGTPKWESPECLMHESYNQKSDVYSYA

ILLWEILTSDFPFRGLS-QVQVAMNVVGNAIRPVIPNVAPPKITKMIKLCWDQEASRRPSMEQVARAI
..|.| .| | |. .    . .|  |     || ||   .. . |.|| ||  .  .||.|.|.    
MMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 87283.m00138.AA LRRK 165-417 24 5.6e-57 195.6 In-house 1-351 (351) Show / Hide 
Range on Protein: 165-417
Range on HMM: 1-351/351
Sequence Identity: 24% (88 aa)

FVIKKKIGSGGFA-DVHEGIQQS--------------------------TQKVVAIKILHST--------------------------------EMSETV
..| ..||.|||.  |. .. ..                            . ||||... .                                |.. ..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FTSFKREIEIQASLSNFAILELVGVCLEAPFYIATEFMPKDCLFKRLH--LQSK-------LKPTQRTIIALGCAIGLAYMHKHN--YIHRDIKSLNILL
| .| .|. |  .|    |. |.|.|.. |. ...|..|   | ..||   |..       .... .  |||  | |..|.|.||   |||| || ||||
FREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

DADDFP------------KICDFGMSR--TLAKSKELMSGGVGTAQWEAPEVINNM---QYNEKADVYSYGILLWEILTSD-FPFRGLS-------QVQV
   . .            ||.||| ||  .  ... . .| ||. .| |||.....   .|.||.|.||.|..|||.|| . .||....       . |.
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMG-VAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI

AMNVVGNAIRPVIPNV-APP-----KITKMIKLCWDQEASRRPSMEQVARAIAC
  .. .  .||.||.   ||        . |..||...  .||...|.   .  
EDKIIEG-LRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 87283.m00138.AA TKL-Unique 167-415 30 2.3e-55 190.28 In-house 1-290 (290) Show / Hide 
Range on Protein: 167-415
Range on HMM: 1-290/290
Sequence Identity: 30% (90 aa)

IKKKIGSGGFADVHEGIQQSTQKVVAIKILH-STEMSETVFTSFKREIEIQASLSNFA----ILELVGVCL----EAP-FYIATEFMPKDCLFKRLH---
. .|||.||.. |  |.  ...  ||||..|   . | ..   |..|. .   ....     |. ..|.|      .| ..| .|..|   | . ||   
FWNKIGEGGYGQVYKGKWRGYP--VAIKQFHPNEDSSNEMMQEFENEVNW---MKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNN

-------LQSKLKPTQRTIIALGCAIGLAYMHKHN--YIHRDIKSLNILLDAD-----DFPKICDFGMSRTLAKSKELMSGG---------VGTAQWEAP
         .|| . ||  .|. .| |. | |  .   ||||.||.|.|.| .        |||||| |....|. .  ...         .|...| ||
NNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAP

EVINN--MQYNEKADVYSYGILLWEILTSDF------PFRGLSQVQVAMNVVG--NAIRPVIPNVAPPKITKMIKLCWDQEASRRPSMEQVARAI
||...   ||.||.||||.|| ||||.|..       |..|..| |..  |       || |||  |. ... |. ||... | ||| ...   .
EVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 87283.m00138.AA S_TKc 165-421 26 1e-51 179.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 165-421
Range on HMM: 1-231/231
Sequence Identity: 26% (72 aa)

FVIKKKIGSGGFADVHEGIQQSTQKVVAIKILHSTEMSETVFTSFKREIEIQASLSNFAILELVGVCLEAPFYIATEFMPK--DCLFKRLHLQSK-----
. | .|||.|.|. |. ..  .|...|||||..          ...|||.|  .     |  | .|. .  .|. .|...     ||.... . .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LKPTQRTIIALGCAIGLAYMHKHNYIHRDIKSLNILLDADDFPKICDFGMSRTLAKSKELMSGGVGTAQWEAPEVINNMQYNE-KADVYSYGILLWEIL
 . . .   ..   . .|.|.|.|. ||||.|  |||||     ||||||..| |       .  .||  . ||||.   .|.  |.|..| |..|.| |
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TSDFPFRGLSQVQVAMNVVGNAIRPVIPNVAPPKITKMIKLCWDQEASRRPSMEQVAR---AIACGEVV
.   ||.   |.|. ....|           .|    .|. |.. . ..||.  .. .   .|.| . .
CGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 87283.m00138.AA Pkinase 165-415 25 1.8e-51 182.09 Pfam 1-293 (293) Show / Hide 
Range on Protein: 165-415
Range on HMM: 1-293/293
Sequence Identity: 25% (74 aa)

FVIKKKIGSGGFADVHEGIQQSTQKVVAIKILHSTEMSETVFTSFKR--EIEIQASLSNFAILELVGVCL-EAPFYIATEFMPKD----CLFKRLH--LQ
..|..|||||.|. | ... ..|.|.||.||.   . .. .  .  |  ||.| ..|.   |..| ...  .   |. .|.....     || ...   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SKL--KPTQRTIIALGCAIGLAYMHKHNYIHRDIKSLNILLDADDFP----KICDFGMSRTL-AKSKELMSGGVGTAQWEAPEVIN-NMQYNEKADVYSY
 ..   . .   ...  . ||.|.|... ||||.|. |||.| .. .    |||||| .. .   ... |.. .||  . |||||. .  |  |.|..|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILLWEILTSDFPFRGL------SQVQVAMNVVGNAIRPVIPNVAP-------------------PKITKMIKLCWDQEASRRPSMEQVARA--I
|..|.| |.  .||.|       .| |.  .. |  ..  .|.  .                   .   . || |...  ..||. ||.     .
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 87283.m00138.AA Pkinase_Tyr 165-415 30 8.6e-50 169.25 Pfam 1-270 (270) Show / Hide 
Range on Protein: 165-415
Range on HMM: 1-270/270
Sequence Identity: 30% (81 aa)

FVIKKKIGSGGFADVHEGIQQ----STQKVVAIKILHSTEMSET-VFTSFKREIEIQASL-SNFAILELVGVCL--EAP--FYIATEFMPKDCLFKRLHL
 .. ||.|.| | .|..|.      .|.  ||.|.|  . |.|     .| ||..|  .| ..  |. |.|||.  . |   || .|.||. .| . |. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----QSKLKPTQRTIIALGCAIGLAYMHKHNYIHRDIKSLNILLDADDFPKICDFGMSRTL-AKSKE--LMSGGVGTAQWEAPEVINNMQYNEKADVYSY
    . .|.. .   ...  | |..| . .|.||||.   |.|.. . . ||||||..|..  ..      .||     | |||.||.. ...| ||.|.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILLWEILT-SDFP-FRGLSQVQVAMNVVGNAIRPVIPNVAPPKITKMIKLCWDQEASRRPSMEQVARAI
|.|.|||.|  . | . |.|  .|   .  .  |  .|  .|..| ...|.||......||..... . .
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 87283.m00138.AA TK 165-415 15 9.6e-50 164.51 In-house 1-486 (486) Show / Hide 
Range on Protein: 165-415
Range on HMM: 1-486/486
Sequence Identity: 15% (74 aa)

FVIKKKIGSGGFA---DVHEGIQQSTQK-------------------------VVAIKILHST-EMSETVFTS--------------FKREIEIQAS--L
 .. ||.|.| |    .|..|. ..  .                          ||.|.|... .||.. |                . .|...  .  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

SNFAILELVGVCLEA-------------PFYIATEFMPKDC----LFKRLHLQSK---------------------------------------------
    |. |.|||..              |..| .|.||. .    | . |.  ..                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LKPTQRTIIALGCAIGLAYMHKH------NYIHRDIKSLNILLDADDF-----------PKICDFGMSR
                               | . |.  ...  | |..|.|..      |..|||.   |.|.. ..             ||.|||.||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

TLA--KSKELMSGGVGTAQ--------------------------------WEAPEVIN---------NMQYNEKADVYSYGILLWEILT--SDFPFRGL
.     .... |..  ...                                | |||..|         .  . .| ||.|.|.|.|||.|     .  |.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SQ---------VQVAMNVV-------------GNAIRPVIPNVAP--------------PKITKMIKLCWDQEASRRPSMEQVARAI
|           .|  ...             |.  |.  |  .|              . .  ... ||. ....||...|. ...
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 87283.m00138.AA HH498 165-415 27 2.5e-48 151.08 In-house 1-284 (284) Show / Hide 
Range on Protein: 165-415
Range on HMM: 1-284/284
Sequence Identity: 27% (79 aa)

FVIKKKIGSGGFADVHEGIQQSTQKVVAIKILHSTEMSETVF------TSFKREIEIQASLSNFAILELVGVCLEAP--FYIATEFMPKDCLFKRL----
.  ..||||| | .|  |      |.||.|   .   ..           | ||. |   |...     |. |.. |  | | |..     || .|    
IEFHEKIGSGSFGKVYKGEWR--NKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIP

----------HLQS----KLKPTQRTIIALGCAIGLAYMHK---HNYIHRDIKSLNILLDADDFPKICDFGMSRTLAKSKE-LMSGGVGTAQWEAPEVIN
          | |      . .  . .|..  | |  | |    |  ||||  | |||...|   .. ||| || .    .  |    |   | ||||  
IGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFS

-NMQYNEKADVYSYGILLWEILTSDFPFRGLSQVQVAMNVVGNAIRPVIPNV----APPKITKMIKLCWDQEASRRPSMEQVARAI
 . .| .|.||.||.. .||..|   ||  . ..  |  .    ||| ||.      | ..  .|  ||... . ||.  |. . .
QCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 87283.m00138.AA TyrKc 165-415 27 8.9e-46 159.31 SMART 1-280 (280) Show / Hide 
Range on Protein: 165-415
Range on HMM: 1-280/280
Sequence Identity: 27% (78 aa)

FVIKKKIGSGGFADVHEGIQQSTQKVVAIKILHSTEMSETVFTSFKREIEIQASL--SNFAILELVGVCLE--------APFYIATEFMPKDCLFKRLHL
 . .||.|.| |  |..|.       ||.| |..          | ||..|  .|  ..  |. |.|||..         | .| .|.||. .| ..|. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

QSK-LKPTQRTIIALGCAIGLAYMHKHNYIHRDIKSLNILLDADDFPKICDFGMSRTLAKS-------KELMS----GGV--GTAQWEAPEVINNMQYNE
  . |.. .   ...  | | .| |..|.||||.   |.|....   ||.|||.|| .          .  ..    ||       | |||.||   ...
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KADVYSYGILLWEILTS-DFPFRG-----LSQVQVAMNVVGNAIRPVIPNV-------APPKITKMIKLCWDQEASRRPSMEQVARAI
| ||.|.|...|||.|  . |  |     .|  .|  .|     .|  ||.       .|... ...| ||. ... ||..... . .
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 87283.m00138.AA DRK 165-417 34 2.2e-45 151.67 In-house 1-258 (258) Show / Hide 
Range on Protein: 165-417
Range on HMM: 1-258/258
Sequence Identity: 34% (89 aa)

FVIKKKIGSGGFADVHEGIQQSTQKVVAIKILHSTEMS-ETVFTSFKREIEIQASLSNFAILELVGVCLEAP-FYIATEFMPKDCLFKRLHLQS-KLKPT
 .|   || |....|  |    ||  ||.| |       |     |.|||..   |    |    | |.. |   | .|.||.  | . || .| ..   
IKIGNRIGRGNYGEVFRGTWRGTQ--VAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWP

QRTIIALGCAIGLAYMHKHN--YIHRDIKSLNILLDADDFPKICDFGMSR--TLAKSKELMSGGVGTAQWEAPEVINNMQYNEKADVYSYGILLWEILTS
 .  ... || |. | |  |   |||| || | | |     |. ||| |      |..      .||  | ||||  |  | |||||||..| |||..| 
LMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTR

DFPFRGLSQVQVAMNVVGNAIRPVIPNVAPPKITKMIKLCWDQEASRRPSMEQVARAIAC
  |. |    || . |     || .|   ||| .. .. ||. . . ||||...   .  
QDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase 87283.m00138.AA Fer 165-416 26 1.8e-43 145.96 In-house 1-283 (283) Show / Hide 
Range on Protein: 165-416
Range on HMM: 1-283/283
Sequence Identity: 26% (74 aa)

FVIKKKIGSGGFADVHEG------IQQSTQKV----VAIKILHSTEMSETVFTSFKREIEIQAS-LSNFAILELVGVC-LEAPFYIATEFMPKDCLFKRL
....||.|.| | .|. |      . . .  |    |. | .... ...     | .|  |  . ..   .  . ||| .| |..|  ||.. ..| ..|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

HLQSK--LKPTQRTIIALGCAIGLAYMHKHNYIHRDIKSLNILLDADDF---PKICDFGMSRTLA--KSKELMS---GGVGTAQWEAPEVINNMQYNEKA
   ..  ..  ..  .... | |..|.|..| ||||| . |.|...|..   .|| ||||||...  ... .|      | .  | |||..... |..| 
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIR-WLAPETWQTGIYSPKT

DVYSYGILLWEILT-SDFPFRG------LSQV--QVAMNVVGNAIRPVIPNVAPPKITKMIK-LCWDQEASRRPSMEQVARAIA
||.|.|...||| |  . |. |      . .|  |  .... .  .. .|| .|| | . ..  ||... . ||.| .. . . 
DVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK