Gene 82588.m00130 (T.vaginalis)

82588.m00130

Species: T.vaginalis
Alias: 82588.m00130, TvagK0697
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
82588.m00130.AA Protein None 251 None Fasta, JSON
82588.m00130.kin_dom Protein Kinase Domain None 197 None Fasta, JSON

Protein domain

Protein domains of 82588.m00130.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82588.m00130.AA CAMK 2-194 19 2.4e-49 156.76 In-house 97-421 (425) Show / Hide 
Range on Protein: 2-194
Range on HMM: 97-421/425
Sequence Identity: 19% (64 aa)

HPNIINIYDYFNE-------------------KNYYVLVL---KFCENG----SLEDYLIQNEN---------------IPESKLMEWAKQILGALSYMH
|||||..|...                     ......|.    .|..|     | ||......               ..|.    . .||. |. |.|
HPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCH

QNNASHHDIKPSNILIDSF-----------------GRIKLADFGIAQFLQK------------------------NEKSMIYGGSVAFIA-PEQFLK--
..|  | |.|| |||.|.                  . ||..||| |.....                        ..|   . |. ...| || ...  
SHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKG

-----------VPYDSFKADAWSFGVTLYMLRFHGRLPFFGN-------------NMMEIHSLMSKGFFE-IPDH-----------------------CS
            ||...|.| || || ||..   |..|| |              |. |..    || .. .|..                       .|
HCNMQNATDEEKPYYGPKCDMWSCGVILYIM-LCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVS

YEFRQIFNHALDPNVETRWSVSQLLD
 | ..  .. | .. | |....| |.
QECKDLIRKMLQVDPEKRMTIEQCLN
Kinase 82588.m00130.AA CAMKL 2-193 30 5.6e-47 147.87 In-house 74-292 (297) Show / Hide 
Range on Protein: 2-193
Range on HMM: 74-292/297
Sequence Identity: 30% (67 aa)

HPNIINIYDYFNEKNY------YVLVLKFCENGS--LEDYLIQNEN----IPESKLMEWAKQILGALSYMHQNNASHHDIKPSNILIDSFG--RIKLADF
||||| .|. .  ...      ..||.  |..|.  | ||......    .||.      .||. |..|.|...  | |||| |||.|. |   ||..||
HPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDF

GIAQFLQK-----NEKSMIYGGSVAFIAPEQFLK--VPYDSFKADAWSFGVTLYMLRFHGRLPFFGNNM--------MEIHSLMSKGFFE-IPDHCSYEF
| . . ..     ..| ..  || .. ||| |..   ||| .|.| || ||.||..   |.||| . ..         . .  |.  ... |. | | . 
GFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAM-VCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DC

RQIFNHALDPNVETRWSVSQLL
|..  . | .| | | .. |..
RDLIRKMLQVNPEKRPTIHQIM
Kinase 82588.m00130.AA Pkinase 2-196 27 3.1e-44 157.51 Pfam 59-293 (293) Show / Hide 
Range on Protein: 2-196
Range on HMM: 59-293/293
Sequence Identity: 27% (66 aa)

HPNIINIYDYFNEKNYYVLVLKFCENG----SLEDYLI--QNENI--PESKLMEWAKQILGALSYMHQNNASHHDIKPSNILIDSFGRI----KLADFGI
||||. .||.| .|... .|. .||.|    .| ||.   .. ..  .|  .  ...||| .| |.|...  | |.||.|||||. | |    |..|||.
HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGL

AQF--LQKNEKSMIYGGSVAFIAPEQFLKVPYDSFKADAWSFGVTLYMLRFHGRLPFFGN------NMMEIHSLMSK--GFFEIPDHCS-----------
| .  . .|.  . . |.  ..|||  .. .|.. |.| ||.|..|| . . ||.|| |       ..|... .  .    |..|  ||           
AKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHF

--------YEFRQIFNHALDPNVETRWSVSQLLDY--V
         |.... .  |... . |..  |.|    .
HWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 82588.m00130.AA MARK 2-193 33 6.3e-40 128.3 In-house 58-257 (262) Show / Hide 
Range on Protein: 2-193
Range on HMM: 58-257/262
Sequence Identity: 33% (68 aa)

HPNIINIYDYFN--EKNY-YVLVLKFCENGSLEDYLIQN--ENIPESKLMEWAKQILGALSYMHQNNASHHDIKPSNILIDSFG--RIKLADFGIAQFLQ
|||||  ....   ...   .|..  ...|.| ||...     ..|.      .||. |..|.|..|  | |||| |||||. |   ||..||| .   .
HPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIP

KNEKSMIYGGSVAFIAPEQFLKVPYDSFKADAWSFGVTLYMLRFHGRLPFFGNN--MMEIHSLMSKGFFEIPDHCSYEFRQIFNHALDPNVETRWSVSQL
 ..|  .  |. .. ||| ||| ||| .|.| || || || .  .|..|| | .  . |..  . .| ..||.| | | |.. .  | .| | | .....
PGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM-VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEI

L
.
M
Kinase 82588.m00130.AA ULK 2-175 24 4.4e-38 130.56 In-house 77-306 (329) Show / Hide 
Range on Protein: 2-175
Range on HMM: 77-306/329
Sequence Identity: 24% (56 aa)

HPNIINIYDYFNEK--NYYVLVLKFCENGSLEDYLIQNEN----------IPESKLMEWAKQILGALSYMHQNNASHHDIKPSNILIDSF----------
||||.  ||.|...  |.. ... .|. | ||.|. .| .          ..|..  .  |||| .. ..|..|  | ||||.||||.            
HPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVH

--GRIKLADFGIAQFLQKN------EKSMI----YGGSVAFIAPEQFL----KVPYDSFKADAWSFGVTLYMLRFHGRLPFFGNNMMEIH-----SL---
  |..|.|||| |......      ....     . |.  . ||. .     . ||...|.| ||.|. .| .   |. ||...  ..       .|   
PNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEM-LYGKPPFYAW-FNDQYLQIIQKLINN

-------MSKGFFEIP-----DHCSYEFRQIF
       . |  ...|     ...| |.....
PPPWPQQIKKQPLQFPKDGNDPQISPECKDLI
Kinase 82588.m00130.AA Ciliate-E2-Unclassified 2-148 28 1e-37 128.39 In-house 80-274 (352) Show / Hide 
Range on Protein: 2-148
Range on HMM: 80-274/352
Sequence Identity: 28% (56 aa)

HPNIINIYDYFNEKNYYVLVLKFCENGSLEDYLIQNEN-----------------IPESKLM-----EWAKQILGALSYMHQNN-ASHHDIKPSNILIDS
||.|.. ...|. |..  .|. .||.|.|..|. ....                 ..| .        ...||| .|.|.|..|   | ||||.|||.|.
HPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDN

FG---RIKLADFGIAQFLQKNEK-------------SMIY---GGSVAFI----APEQFLKVPYDS---FKADAWSFGVTLYMLRFHGRLPFFGNN
 |   .||..||||. ..|.|..             ....    |.  ..    ||| . .  ||    .|.| ||.|| || .   |..||..||
NGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEM-LFGYYPFYDNN
Kinase 82588.m00130.AA Ciliate-E2 2-194 22 1.4e-37 126.53 In-house 91-361 (365) Show / Hide 
Range on Protein: 2-194
Range on HMM: 91-361/365
Sequence Identity: 22% (64 aa)

HPNIINIYDYFN--EKNYYVLVLKFCENGSLEDYLIQN-----------ENIPESKLMEWAKQILG---------------ALSYMHQNN-ASHHDIKPS
|||||..|..|    .|.. ||. .|. |.|.||...|           ... | .  .  ||||                || |.|..|   | ||||.
HPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPE

NILIDSFGRIKLADFGIAQFLQKN----------EKSMIYG-----------------------GSVAFIAPEQFLKVPY--------DSFKADAWSFGV
|||.     ||..|||........          .. |  .                       |.  . ||| . . .|         ..|.| ||.||
NILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGV

TLYMLRFHGRLPFFGNNMMEIHSLMSKGFFE--------------IPDHCSYEFRQIFNH----ALDPNVETRWS-VSQLLD
.||..   |..||    . .|.    . ...              .....| |  ....      |. . | | .  .|.|.
ILYEM-LFGKPPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 82588.m00130.AA GIN4 2-198 33 1.2e-35 111.07 In-house 93-293 (293) Show / Hide 
Range on Protein: 2-198
Range on HMM: 93-293/293
Sequence Identity: 33% (67 aa)

HPNIINIYDYFNEKNYYVLVLKFCENGSLEDYLIQNENIPESKLMEWAKQILGALSYMHQNNASHHDIKPSNILIDSFGR-IKLADFGIAQFLQKNEKSM
|||.. .|| . ..|   ||| . | | | .||..   .||   ... .||.  .|| |  |  | |.|| |.|.|.. . ||.||||.|    .|.   
HPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFGMAALETDNKLLE

IYGGSVAFIAPEQFLKVPYDSFKADAWSFGVTLYMLRFHGRLPFFGN--NMMEIHSLMSKGFFEIPDH--CSYEFRQIFNHALDPNVETRWSVSQLLDYV
   ||  . |||    .||. | .| || || |. |   |.|||  .  |. ..   . || .|.|.    | | . .    |    | |  . ..|   
TSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFAL-LTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPEKRIKTRDILKHP

CK
  
LI
Kinase 82588.m00130.AA ULK 2-175 24 9.1e-35 120.81 In-house 72-301 (324) Show / Hide 
Range on Protein: 2-175
Range on HMM: 72-301/324
Sequence Identity: 24% (56 aa)

HPN--IINIYDYFNEK--NYYVLVLKFCENGSLEDYLIQNEN---------IPESKLMEWAKQILGALSYMHQNNASHHDIKPSNILIDSF---------
|||  |.  ||.|...  |.. ... .|. | ||.|. .| .         ..|..  .  |||. .. ..|..|  | ||||.||||            
HPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV

---GRIKLADFGIAQFLQKN-EKSMIY----G-----GSVAFIAPEQFL----KVPYDSFKADAWSFGVTLYMLRFHGRLPFFGNNMMEIH----SL---
   |..|.|||| |.....| .  ...    .     |.  . ||. .     . ||...|.| ||.|. .| .   |. |||..  ..      .|   
HPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEM-LYGKYPFFSW-FNDQYLYIQKLINN

-------MSKGFFEIPD-----HCSYEFRQIF
       . .  ...|.     ..| |.....
GKEQQIYIKNQPIQFPKPPKDPKISPECKDLI
Kinase 82588.m00130.AA STE 1-193 22 6.7e-33 113.55 In-house 88-352 (359) Show / Hide 
Range on Protein: 1-193
Range on HMM: 88-352/359
Sequence Identity: 22% (62 aa)

MHPNIINIYDYFNEK-------NYYVLVLKFCENGSLEDYLI------QNEN--------IPESKLMEWAKQILGA-LSYMHQNNASHHDIKPSNILIDS
|||||.. |...  .       ..  ... ....|||.| .       .. |        .||| .   ..||| . |.| |...  | ||||.|||.  
MHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--

FGRIKLADFGIAQFLQKN-----------------EKSMIYGGSVAFIAPEQFLK------VPYDSFKADAWSFGVTLYMLRFHGRLPFFGNNMMEIHSL
   .||.|||..  |...                 .|.    |.  . |||  ..       .|| .|.| ||.| |.  .   |. |..  . |.   .
---VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEM-ATGKPPWHDMHPMRAMFM

MS----------------KGFFEIPD-------------------HCSYEFRQIFNHALDPNVETRWSVSQLL
.                 ..   .||                   ..| ||..  |. |. . . |...||||
IPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLL
Kinase 82588.m00130.AA TKL 2-134 20 9.7e-31 107.92 In-house 84-280 (364) Show / Hide 
Range on Protein: 2-134
Range on HMM: 84-280/364
Sequence Identity: 20% (41 aa)

HPNIINIYDYFNEKNY-------------YVLVLKFCENGSLEDYLIQNENIPESKLMEWAKQILGALSYMHQNN--------ASHHDIKPSNILIDSFG
||||. .. | .. ..             . .|  .|..|||..||.       .... ||..|  ...|.|..|          | |.|..|||.|. .
HPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENW

R--------------IKLADFGIAQFLQKNE--------------------KSMIYGGSVAFIAPEQFLKVPYDS---------------FKADAWSFGV
.              .|..|||...|.....                    ..|  .|. .. ||| . . ....                |.| .|||.
TNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGI

TLY
 |.
VLW
Kinase 82588.m00130.AA S_TKc 1-196 22 3.8e-27 97.44 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-196
Range on HMM: 1-231/231
Sequence Identity: 22% (58 aa)

M---------------------------------------------HPNIINIYDYFNEKNYYVLVLKFCEN--GSLEDYLIQNEN------IPESKLME
                                              ||||...||.| . ... .|. .|..  |.| ||. ..        .||     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARF

WAKQILGALSYMHQNNASHHDIKPSNILIDSFGRIKLADFGIAQFLQKNEKSMIYGGSVAFIAPEQFLKVPYDSFKADAWSFGVTLYMLRFHGRLPFFGN
...||. || |.|...  | |.||.|||.|.  .||..|||.| .|      . . |.  ..||| .   .|. .|.| ||.|..|| .   |. ||   
YMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--

NMMEIHSLMSKGFFEIPDHCSYEFRQIFNHALDPNVETRWSVSQLLD---------YV
.|...  ..           | |.... .. |. . | |... ..|          ..
QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 82588.m00130.AA TyrKc 1-196 18 4.4e-10 -59.63 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-196
Range on HMM: 1-280/280
Sequence Identity: 18% (51 aa)

M-------------------------------------------------HPNIINIYDYFNEK-------NYYVLVLKFCENGSLEDYLIQNEN-IPES
                                                  ||||...| .  ..         . .|. ....|.| |||  ... .. .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

KLMEWAKQILGALSYMHQNNASHHDIKPSNILIDSFGRIKLADFGIAQFLQKN-----EKSMIY-----GGS----VAFIAPEQFLKVPYDSFKADAWSF
.| ... ||    .| |..|  | |.   |.|... ...| .||| . ..        .|...      ||     .   ||| . .  . ..| | |||
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-TTKSDVWSF

GVTLYMLRFHGRLPFFG-----NNMMEIHSLMSKG-FFEIPDH--------CSYEFRQIFNHALDPNVETRWSVSQLLDYV
||... .   |  |  |      .  |.. .  .|   ..|..        |. |  ||     . . | | . |.. .. 
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 82588.m00130.AA Pkinase_Tyr 2-97 24 1e-05 19.96 Pfam 63-165 (270) Show / Hide 
Range on Protein: 2-97
Range on HMM: 63-165/270
Sequence Identity: 24% (25 aa)

HPNIINIYDYFN-EKNY--YVLVLKFCENGSLEDYLIQ----NENIPESKLMEWAKQILGALSYMHQNNASHHDIKPSNILIDSFGRIKLADFGIAQFLQ
||||.. |     ..    . .|. ....|.| ||| .    ..... . | ... ||  ...| ...|  | |.   |.|... . .| .||| |  ..
HPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIY

KNE
. .
NDD
Kinase 82588.m00130.AA Pkinase_Tyr 121-134 50 0.989027 3.1 Pfam 192-205 (270) Show / Hide 
Range on Protein: 121-134
Range on HMM: 192-205/270
Sequence Identity: 50% (7 aa)

SFKADAWSFGVTLY
. | | |||||...
TTKSDVWSFGVLMW