97483.m00096

Species: T.vaginalis
Alias: 97483.m00096, TvagK0983
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
97483.m00096.AA Protein None 398 None Fasta, JSON
97483.m00096.kin_dom Protein Kinase Domain None 231 None Fasta, JSON

Protein domain

Protein domains of 97483.m00096.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 97483.m00096.AA AGC 182-264 24 4.7e-22 52.41 In-house 275-395 (395) Show / Hide
Range on Protein: 182-264
Range on HMM: 275-395/395
Sequence Identity: 24% (31 aa)

PPEYLVANSYSAAADFWD--LGIFLYYCVVGGSPFPMDN----------KETITGMIV----------AYP----------NFLSQSIIDLFKKLITASP
.|| |    |. |.| |   ||...|  ..| .||  ||          .. .   |            .|           ..|.   || |||..  |
APEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDP

AHRYN----------TRDIKEHPWF
..|            . .||.||||
EKRLGCGGNDFGDKGAEEIKNHPWF

Kinase 97483.m00096.AA Ciliate-E2-Unclassified 41-264 19 7.7e-21 69.04 In-house 34-352 (352) Show / Hide
Range on Protein: 41-264
Range on HMM: 34-352/352
Sequence Identity: 19% (64 aa)

VSIKVYSKKFLAIDNNKEYFENDLYCLK----------------TFFHPFIAKYITKLEDSKFVYIVLEPMRGGTFKELLEAKTR---------------
..... .|. .  | ..   .. . ..|                 . |||| |..   .| . .|||.| ..||. .. .. .                 
KIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQR

--WNEAQAR-----PYFAQLYFIIEYMQTQMNMIHGNLCLDILMVDENN---VIRCVDFWGTQ--------------------PNSGSAACGTQLFAPLP
    | ||.      ||||.   .||.  . | || .. .. ...|.|.    |.  ||                        ..  .  |||  . |  
KIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMP-Q

FQPPEYLVANSYS----AAADFWDLGIFLYYCVVGGSPFPMDNKET----------------ITGMIVA-------YPN-----FLSQSII----DLFKK
 ..||.|  . |.     ..|.| ||. ||... |  ||.  |.|                 .   | .       .|.      .|.. .    ||..|
YTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQK

LITASPAHRYNTRDIKEHPWF
..   |  |..  .|..||||
MLKKNPNKRITFEQILNHPWF

Kinase 97483.m00096.AA MELK 32-264 25 5.1e-20 64.81 In-house 18-254 (254) Show / Hide
Range on Protein: 32-264
Range on HMM: 18-254/254
Sequence Identity: 25% (60 aa)

AHHSVTSQEVSIKVYSKKFLAIDNNKEYFENDLYCLKTFFHPFIAKYITKLEDSKFVYIVLEPMRGGTFKELLEAKTRWNEAQARPYFAQLYFIIEYMQT
| | .| | |.||.  |. |  |  .   . ..  || . |  | .    .|  . ...|.|   || . . .  . | .| ..| .| |.   | |.  
ACHILTNQMVAIKIMDKNQLGHDLPR--VKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETRHFFRQIVSAIAYVHS

QMNMIHGNLCLDILMVDENNVIRCVDFWGTQPNSGSAACG--TQLFAPLPFQPPEYLVANSYSAA-ADFWDLGIFLYYCVVGGSPFPMDNKETITGMIVA
|    | .|  . |..||.  .. .||       |             . .  || .   .|  . || | .|| ||  ..|  ||  || . .   |. 
QG-YAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPFDDDNMMIMYKKIMS

----YPNFLSQSIIDLFKKLITASPAHRYNTRDIKEHPWF
     |..|| . ..| ....   | .|   ... .||| 
GCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV

Kinase 97483.m00096.AA PKN 72-264 29 5.2e-18 58.14 In-house 61-260 (260) Show / Hide
Range on Protein: 72-264
Range on HMM: 61-260/260
Sequence Identity: 29% (60 aa)

HPFIAKYITKLEDSKFVYIVLEPMRGGTFKELLEAKTRWNEAQARPYFAQLYFIIEYMQTQMNMIHGNLCLDILMVDENNVIRCVDFWGTQPNSGSAACG
|||.   .. .  .. |. |.| . ||     .     ..|..|. | |     ..|.  . ..|   | || |..|..  ..  ||   . . |     
HPFLVNLFACFQTEEHVCFVMEYAMGGDLMMHIHEDV-FSEPRACFYAACVVLGLQYLH-EHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDR-

TQLFAPLP-FQPPEYLVANSYSAAADFWDLGIFLYYCVVGGSPFPMDNKETITGMIVA----YPNFLSQSIIDLFKKLITASPAHRY-----NTRDIKEH
|  |   | |  || |  .||  | |.| ||. .|  .|| .||| |. | .   ||     || |||   |.. ..|.  .| .|         ||| .
TSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGECPFPGDDEEEVFDCIVNDDVRYPRFLSVEAIAIMRRLLRKNPERRLGAGERDAEDIKMQ

PWF
|.|
PFF

Kinase 97483.m00096.AA Ciliate-E2 178-264 23 8e-16 50.79 In-house 251-365 (365) Show / Hide
Range on Protein: 178-264
Range on HMM: 251-365/365
Sequence Identity: 23% (28 aa)

LPFQPPEYLVANS---------YSAAADFWDLGIFLYYCVVGGSPFPMDNKETITGMIVAYPNF------------------LSQSIIDLFKK----LIT
.....|| |   .         |. ..|.| ||. ||... |  ||     . |    . .|..                  .||. .||.||    .. 
PGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQ

ASPAHRYN-TRDIKEHPWF
  |  |..   .|..||||
KDPEKRITGWEQILNHPWF

Kinase 97483.m00096.AA CAMKL 178-264 24 1.6e-15 45.88 In-house 197-297 (297) Show / Hide
Range on Protein: 178-264
Range on HMM: 197-297/297
Sequence Identity: 24% (25 aa)

LPFQPPEYLVA--NSYS-AAADFWDLGIFLYYCVVGGSPFPMDN-------------KETITGMIVAYPNFLSQSIIDLFKKLITASPAHRYNTRDIKEH
.|...|| .     .|   ..| | .|. ||  |.|  ||  |.             |. ..      ....| . .|| .|. .  | .|..  .|..|
PPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH

PWF
||.
PWM

Kinase 97483.m00096.AA Delta 72-264 23 1.1e-14 49.56 In-house 59-259 (259) Show / Hide
Range on Protein: 72-264
Range on HMM: 59-259/259
Sequence Identity: 23% (47 aa)

HPFIAKYITKLEDSKFVYIVLEPMRGGTFKELLEAKTRWNEAQARPYFAQLYFIIEYMQTQMNMIHGNLCLDILMVDENNVIRCVDFWGTQPNSGSAACG
|||... .      .... |.| . ||     .  . |..|. || | . .   .... .. ..|   | || ...| .  |.  ||   . |       
HPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEKRARFYACEIICGLQFLHKK-GIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGE-KK

TQLFAPLP-FQPPEYLVANSYSAAADFWDLGIFLYYCVVGGSPFPMDNKETITGMIVA----YPNFLSQSIIDLFKKLITASPAHRYNT-----RDIKEH
.. |   | .  || .  . |... |.|  |. .|  ..| |||  .. . .   |.     || ....   |..|||.   | .|         ||..|
ASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPFHGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQH

PWF
..|
CFF

S_TKc 97483.m00096.AA S_TKc 22-264 22 1.4e-14 36.93 SMART 1-231 (231) Show / Hide
Range on Protein: 22-264
Range on HMM: 1-231/231
Sequence Identity: 22% (60 aa)

MKNERF-------VLWGAHHSVTSQEVSIKVYSKKFLAIDNNKEYFENDLYCLKTFFHPFIAKYITKLEDSKFVYIVLEPMRG--GTFKELLEAKTR---
 .  |        . . ..|  | ..| ||. .          | ... . .||   ||.| |..   .| ...|.|.| . |  |. ..... . |   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---WNEAQARPYFAQLYFIIEYMQTQMNMIHGNLCLDILMVDENNVIRCVDF-WGTQPNSGSAACGTQLFAPLPFQPPEYLVANSYSA-AADFWDLGIFL
    .| .|| |..|.   .||.  . . ||  |  . ...||  .|   ||   .|         | .   . . .|| |   .|.  ..| | .|. |
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

YYCVVGGSPFPMDNKETITGMIVAYPNFLSQSIIDLFKKLITASPAHRYNTRDIKE-------HPWF
| ...|  |||  . ...  .|.      |.. .|. .|. .  |..|.   .. .       ||||
YEMLCGYPPFP--QMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 97483.m00096.AA RSK 182-264 28 8.4e-12 39.76 In-house 176-278 (278) Show / Hide
Range on Protein: 182-264
Range on HMM: 176-278/278
Sequence Identity: 28% (29 aa)

PPEYLV---ANS-YSAAADFWDLGIFLYYCVVGGSPFPM----DNKETITGMIVAY-----P--NFLSQSIIDLFKKLITASPAHRYN-----TRDIKEH
.|| |     .. ...|.| | ||. .|   .| .|| .    . ||... .  .      |  ..|||   || .|. .  |. |..     . .||.|
APEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQH

PWF
|||
PWF

Kinase 97483.m00096.AA AMPK 230-264 42 1.3e-10 27.81 In-house 220-254 (254) Show / Hide
Range on Protein: 230-264
Range on HMM: 220-254/254
Sequence Identity: 42% (15 aa)

PNFLSQSIIDLFKKLITASPAHRYNTRDIKEHPWF
| |||... || |.. .  |  |..  ||..||||
PKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase 97483.m00096.AA Ciliate-E2b 191-264 23 1.7e-09 25.16 In-house 187-272 (272) Show / Hide
Range on Protein: 191-264
Range on HMM: 187-272/272
Sequence Identity: 23% (20 aa)

YSAAADFWDLGIFLYYCVVGGSPF------PMDNKETITGM--IVAYPNFLSQSII--DLFKKLITASPAHRY--NTRDIKEHPWF
|. ..| | .||.||   .|. |.      |    . |.     . .|....  .   .|  ..   .|  |        | ||||
YTYKVDIWSVGICLYEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYSWLKSHPWF

Kinase 97483.m00096.AA Ciliate-E2 36-140 15 1.2e-07 22.32 In-house 45-187 (365) Show / Hide
Range on Protein: 36-140
Range on HMM: 45-187/365
Sequence Identity: 15% (22 aa)

VTSQEVSIKVYSKKFLAIDNNKEYFE----------NDLYCLKTFFHPFIAKYITKLE--DSKFVYIVLEPMRGGTFKELLEAKTRW-----------NE
|..... .|...|. . . .....            | .  |..  ||.| |..   .  | . .|.|.|   ||. ..... .  .           .|
VKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTE

AQARPYFAQLYF---------------IIEYMQTQMNMIHGNL
 ... ...|.                  .||.  . | || ..
KEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDI

Kinase 97483.m00096.AA Pkinase 182-264 20 3.8e-07 26.37 Pfam 179-293 (293) Show / Hide
Range on Protein: 182-264
Range on HMM: 179-293/293
Sequence Identity: 20% (23 aa)

PPEYLV-ANSYSAAADFWDLGIFLYYCVVGGSPFPMD------NKETITGMIVAYPNFLS-------------------------QSIIDLFKKLITASP
.|| .  .. |. ..| | .|. ||. . |  ||| .      ..  .  .|   |.  .                         .. .|. |....  |
APEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDP

AHRYNTRDIKEHPWF
. |.. ..|..||||
KKRPTAEQILQHPWF

Kinase 97483.m00096.AA Ciliate-E2b 67-158 22 6.9e-07 17.15 In-house 54-146 (272) Show / Hide
Range on Protein: 67-158
Range on HMM: 54-146/272
Sequence Identity: 22% (21 aa)

LKTFFHPFIAKYITKLEDSKFVYIVLEPMRGGTFKELLEAKT--RWNEAQARPYFAQLYFIIEYMQTQMNMIHGNLCLDILMVDENNVIRCVDF
|..  |||| |.|    |....| ..|  .|. . ...        .. ... |.|..  ..|| . . | |.. .     |||..  .. .|.
LEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLSTYDSQFYIASICLCLEYLH-NQNIIYRDIKPENIMVDHKGYMKLIDM

Kinase 97483.m00096.AA AMPK 32-158 26 9.6e-07 16.12 In-house 18-144 (254) Show / Hide
Range on Protein: 32-158
Range on HMM: 18-144/254
Sequence Identity: 26% (34 aa)

AHHSVTSQEVSIKVYSKKFLAIDNNKEYFENDLYCLKTFFHPFIAKYITKL-EDSKFVYIVLEPMRGGTFKELLEAKTRWNEAQARPYFAQLYFIIEYMQ
. |  |...| ||.  |. .. .  .|  .. .  || | || | .    . |  .  ..|.|   ||   .    ..| .| .|. .|.|    .||. 
GTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYCH

TQMNMIHGNLCLDILMVDENNVIRCVDF
 . .  |  | .  |  |.|. |  |||
-RHMIVHRDLKPENLLLDHNKNIKIVDF

Kinase 97483.m00096.AA CAMKL 32-122 24 7e-06 14.53 In-house 18-136 (297) Show / Hide
Range on Protein: 32-122
Range on HMM: 18-136/297
Sequence Identity: 24% (29 aa)

AHH-SVTSQEVSIKVYSKKFLAIDNNKEYF------ENDL------YCLKTFF---HPFIAKYITKLEDSKF------VYIVLEPMRGGT--FKELLEAK
|.| . | ..| ||.. || .  | ...        | |.       ..| .    || | |    .|....      .|.|.|   ||     . ....
ATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKH

----TRWNEAQARPYFAQL
     |  | .|| || |.
GHRRGRMPEHEARRYFRQI

Kinase 97483.m00096.AA RSK 72-129 24 2.4e-05 15.92 In-house 60-120 (278) Show / Hide
Range on Protein: 72-129
Range on HMM: 60-120/278
Sequence Identity: 24% (15 aa)

HPFIAKYITKLEDSKFVYIVLEPMRGGTFKELLEAKTR---WNEAQARPYFAQLYFIIEYM
|||| ..    .. . .|...| .||| . . |. . .   . |  |. |.|..   .|..
HPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHL

Kinase 97483.m00096.AA AGC 72-137 26 3.1e-05 7.92 In-house 83-177 (395) Show / Hide
Range on Protein: 72-137
Range on HMM: 83-177/395
Sequence Identity: 26% (26 aa)

HPFIAK----YITK-L----EDSKF--VYIVLEPMR---------GG-TFKELLE---AKTRWNEAQARPYFAQ-------LYFIIEYMQTQMNMIH
|| | |    .|.| |    .| .   .|.|.| |          ||  .   |     . | .| .|| |.|.       .   .||.  .|. ||
HP-I-KSHHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIH

Kinase 97483.m00096.AA Pkinase 32-122 20 0.004266 12.03 Pfam 18-117 (293) Show / Hide
Range on Protein: 32-122
Range on HMM: 18-117/293
Sequence Identity: 20% (20 aa)

AHHSVTSQEVSIKVYSKKFLAIDNNKEYFE-NDLYCLKTFFHPFIAKYITKLEDSKFVYIVLEPMRGG----TFKELLE--AKTRW--NEAQARPYFAQL
.||  |...| .|. .|.    . ... .  . .. .| . ||.| ...   ||.. .|.|.| ..||      .....  ....    | ... |. |.
CHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQI