96044.m00352

Species: T.vaginalis
Alias: TvagK0346, 96044.m00352
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
96044.m00352.AA Protein None 967 None Fasta, JSON
96044.m00352.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of 96044.m00352.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 96044.m00352.AA TKL 41-290 22 1.6e-66 227.35 In-house 1-364 (364) Show / Hide
Range on Protein: 41-290
Range on HMM: 1-364/364
Sequence Identity: 22% (83 aa)

IGEGGFASVYKGIDRRNG--------NFVAIKQVFE------SRVYVD-------------------NFRRFSNEIRTMARCHCCCLTKLIGFTTTKP--
||.|||. ||||. | .|        . ||.|.  .      ..   .                   .. .. .||. | |...  . ...|. .  |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YSIITEFEENLSLDSQLTNKKKADIFTGTRLSKIAMGIAFGMQHVHMLG--------ILHRDLKLSNILLDRDYN-------------
            . |..|. .. || ..|.           .. ..|..|| ||.. |. .        |.||||| .|||.|....             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PKLCDFGIARFYKDDME--------------------LTRKIGTPIYIAPKVFTDN----------------HYTKKADVYSYAILLYELSEKTRPFKK
 .|.||||..|| . ...                    . ...||| . || |. ..                 |..|.||||..|.|.|.    ||...
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

PEGLSVA------EIIQKVVQAGQRPQFT------------DVTPIPLRKLIESCWDADPTKRPEFSYIYEQF
.   ..       |.. .|.. |.||               . .| ...||.. |||.||.||| |. | ...
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase 96044.m00352.AA TKL-Unique 37-290 28 4.1e-59 202.69 In-house 1-290 (290) Show / Hide
Range on Protein: 37-290
Range on HMM: 1-290/290
Sequence Identity: 28% (83 aa)

ILDSIGEGGFASVYKGIDRRNGNFVAIKQVF-ESRVYVDNFRRFSNEIRTMARCH-CCCLTKLIGFTT----TKP-YSIITEFEENLSLDSQLT------
.. .|||||...||||. |  |  ||||| . .. .  .  . |.||...| . |    .....|...    . | ..|..|. .  ||.. |.      
FWNKIGEGGYGQVYKGKWR--GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---NKKKADIFTGTRLSKIAMGIAFGMQHVHMLG--ILHRDLKLSNILLDRD-----YNPKLCDFGIARFYK--DDMELTRK--------IGTPIYIAPK
   |...   ..  .  |.|  || || . | ..  |.||||| ||.|.|..     .| |.||||...| .  ..| ....        .|.....|| 
NNNNNNCK--LNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPE

VFTD--NHYTKKADVYSYAILLYELSEKTR------PFKKPEGLSVAEIIQKVVQAGQRPQFTDVTPIPLRKLIESCWDADPTKRPEFSYIYEQF
|...  ..|..|.||||..| |.|. . ..      |... .  ...|.. ..   ..||   .  |  .|.||. ||. ||..|| |. |..  
VLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYM-EENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase 96044.m00352.AA MLK 35-290 25 1.3e-49 170.28 In-house 1-291 (291) Show / Hide
Range on Protein: 35-290
Range on HMM: 1-291/291
Sequence Identity: 25% (75 aa)

IEILDSIGEGGFASVYKGIDRRNG---NFVAIKQVF-------ESRVYVDNFRRFSNEIRTMARCH--CCCLTKLIGFTTT-KPYSIITEFEENLSLDSQ
|...  ||.|.| .|.||  | .      ||.|.|.       ..    ..|... .. | . .     |    . . . . ... |..|. |. || . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LTN-KKKAD----------IFTGTRLSKIAMGIAFGMQHVHMLG---ILHRDLKLSNILLDR------DYNPKLCDFGIARFYKDDME-LTRKIGTPIYI
| . ..| .          . .   . ..|. .| ||.  |..    | ||||| .|||.|.      . . | ||||..|. ..  .  . ..||... 
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APKVF---TDNHYTKKADVYSYAILLYELSEKTRPFKKPEGLSVAEIIQKVVQAGQRPQFTDVTPIPLRKLIESCWDADPTKRPEFSYIYEQF
|| |.     . |..|.||.|....|.|.  .  |.|  .... ..|. .|.. |.||      | .. ||.. ||..|| ||| |..| ...
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYK--QHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase 96044.m00352.AA LRRK 35-292 25 2.8e-47 163.37 In-house 1-351 (351) Show / Hide
Range on Protein: 35-292
Range on HMM: 1-351/351
Sequence Identity: 25% (91 aa)

IEILDSIGEGGFA-SVYKGIDRRN--------------------------GNFVAIKQVFE--------------------------------SRVYVDN
..|  .||.|||. .||... |..                          .. ||||.                                   ..    .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FRRFSNEIRTMARCHCCCLTKLIGFTTTKPYSIITEFEENLSLDSQLTNKKK-------ADIFTGTRLSKIAMGIAFGMQHVHMLG--ILHRDLKLSNIL
|| | .|.  | . .  .. .|.|| . .|. ...|.  . .|.. | |||.       |.|  ...| |||. || ||.. |     |.|||||  |||
FREFRHEVWIMSHLNHPNIVSLKGF-CIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKL-KIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

L---D---------RDYNPKLCDFGIAR-FYKDDME-LTRKIGTPIYIAPKVFTDN---HYTKKADVYSYAILLYELSEKT-RPFKK---PEGLSVAEII
|   .          ... |..|||| | |. . |. . .. |.|.. || .  .|    || |.|.||....|.||   . .||     .  ..  |.|
LWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI

QKVVQAGQRPQFT-D-VTPI----PLRKLIESCWDADPTKRPEFSYIYEQFKS
.. .. |.|| .  .  .|      . .||..||..||.||| ||.| .. ..
EDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase 96044.m00352.AA Pkinase 35-290 23 7.8e-47 166.68 Pfam 1-293 (293) Show / Hide
Range on Protein: 35-290
Range on HMM: 1-293/293
Sequence Identity: 23% (70 aa)

IEILDSIGEGGFASVYKGIDRRNGNFVAIKQVFESRVYVDNFRRFSN--EIRTMARCHCCCLTKLIGFTTTKPYSI-ITEFEENL----SLDSQLT--NK
..|.  ||.|.|..|||.... .|  ||.|..  ..   .  ..  .  ||. |.|.....  .|... ..|..   ..|. |.     .| . ..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KKADIFTGTRLSKIAMGIAFGMQHVHMLGILHRDLKLSNILLDRDYNP----KLCDFGIARF--YKDDMELTRKIGTPIYIAPKVFT-DNHYTKKADVYS
..   |.   . ...  |. |... |  ||.|||||..|||.|.....    |.||||.|..  |  .  .|   ||| |.|| |   ...|..|.|..|
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

YAILLYELSEKTRPFKKP----EGLSVAEIIQKVVQAGQRPQFTDVTP-------------------IPLRKLIESCWDADPTKRPEFSYIYEQ--F
. ..|||.  .  ||.      . ..  ..|... ..  . ..    .                    .....|..|.. ||.||| .  | .   |
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 96044.m00352.AA S_TKc 35-291 25 1.7e-45 158.35 SMART 1-231 (231) Show / Hide
Range on Protein: 35-291
Range on HMM: 1-231/231
Sequence Identity: 25% (70 aa)

IEILDSIGEGGFASVYKGIDRRNGNFVAIKQVFESRVYVDNFRRFSNEIRTMARCHCCCLTKLIGFTTTKPYSIITEFEEN--LSLDSQLTNKKKADI--
 |||. ||.|.|..|||..... |  ||||..          ... .||. . . |.  . ||...  .. . ...|. ..   .| . . ....     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-FTGTRLSKIAMGIAFGMQHVHMLGILHRDLKLSNILLDRDYNPKLCDFGIARFYKDDMELTRKIGTPIYIAPKVFTDNHYTK-KADVYSYAILLYELSE
 |.  .  ...  |. .... | .||.||||| .|||||.  . |.||||.||..      |  .||| |.|| |.   .|.| |.|..|  ..|||.  
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

KTRPFKKPEGLSVAEIIQKVVQAGQRPQFTDVTPIPLRKLIESCWDADPTKRPEFSYIYE--------QFK
   ||       ......|..            . ... .|. |.. ||.|||    . .        .. 
GYPPFP-----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 96044.m00352.AA Dicty5 35-294 29 4.4e-41 139.14 In-house 1-260 (260) Show / Hide
Range on Protein: 35-294
Range on HMM: 1-260/260
Sequence Identity: 29% (78 aa)

IEILDSIGEGGFASVYKGIDRRNGNFVAIKQVFESRV-YVDNFRRFSNEIRTMARCH--CCCLTKLIG-FTTTKPY-SIITEFEENLSLDSQLTNKKK--
. . | |  |    ||.||   .|  |||| |. . .    .   |  |.  |         ...  |  .  . |  ..||.  | || . |  ..|  
VSFHDWIASGASGRVYNGI--YKGMDVAIK-VYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTT

-ADIFTGTRLSKIAMGIAFGMQHVHMLGILHRDLKLSNILLDRDYNPKLCDFGIARFYKDDMELTRKIGTPIYIAPKVFTDNHYTKKADVYSYAILLYEL
   |  ...|. .|..|| .|.|.|  .| |||||  |.|.  ..  |. |||. ||     . |  .||. . |. .|. . |. |.||||..| |.|.
GQPIAYFQQLH-MAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEM

SEKTRPFKKPEGLSVAEIIQKVVQAGQRPQFTDVTPIPLRKLIESCWDADPTKRPEFSYIYEQFKSGK
  .  |..     . . ...|    | ||      |    .||..||   | .|| |  | . |.|  
FTRKEPYDNINNWNIPVMVMK----GERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII

Kinase 96044.m00352.AA Dicty4 138-292 33 9.7e-41 133.7 In-house 116-277 (277) Show / Hide
Range on Protein: 138-292
Range on HMM: 116-277/277
Sequence Identity: 33% (54 aa)

KIAMGIAFGMQHVHM--LGILHRDLKLSNILLDRDYNPKLCDFGIARFYKDDMELTR----KIGTPIYIAPKVFTDNHYTKKADVYSYAILLYELSEKTR
..|  .| ||.. |     |.||||| .|.| | ... | ||||...  | . ...      .||| . || |   . |. ||||||..|.|.|.  .  
RMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQE

PFKKPEGLSVAEIIQKVVQAGQRPQFTDVTPIPLRKLIESCWDADPTKRPEFSYIYEQ--FKS
|. | .. .  ...  |.. . ||   | .| ....||. ||| ||..|| |. | ..    .
PYQK-HHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase 96044.m00352.AA TyrKc 35-290 27 4.7e-40 140.29 SMART 1-280 (280) Show / Hide
Range on Protein: 35-290
Range on HMM: 1-280/280
Sequence Identity: 27% (79 aa)

IEILDSIGEGGFASVYKGIDRRNGNFVAIKQVFESRVYVDNFRRFSNEIRTMARC--HCCCLTKLIGFTTT--------KPYSIITEFEENLSLDSQLTN
|. .. .||| |  ||||. .     ||.| . |.       . | .|.| | .   |  .. .|.|  |.        .|. |..|. .. .|.. | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KKKADIFTGTRLSKIAMGIAFGMQHVHMLGILHRDLKLSNILLDRDYNPKLCDFGIARFYKDD------MELTRK----IGT---PI-YIAPKVFTDNHY
...   ..   | ...  || ||.. |  .. ||||   |.|.....  | .||| .|. .||       .  ||     |    ||   || .. .. .
HRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TKKADVYSYAILLYELSEKTRPFKKPEG-----LSVAEIIQKVVQAGQRPQFTDV-------TPIPLRKLIESCWDADPTKRPEFSYIYEQF
| | ||.|. ....|.   |.  . ..|     .| .|.|..| | . .||  ..        |  . .....||..|| .|| || |.|.|
TTKSDVWSFGVCMWEIF--TYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 96044.m00352.AA STE 35-281 20 7.6e-40 138.4 In-house 1-346 (359) Show / Hide
Range on Protein: 35-281
Range on HMM: 1-346/359
Sequence Identity: 20% (72 aa)

IEILDSIGEGGFASVYKGIDRR---------------NGNFVAIKQVFESR---------------VYVDNFRRFSNEIRTMARCH--CCCLTKLIGFTT
 |... ||.|.| .|||....                .|...||||.  ..               .  ... .. .||..| .|.  .    | .|   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TKP--------YSIITEFEENLSLDSQLTNKKKADI-----------FTGTRLSKIAMGIAFG-MQHVHMLGILHRDLKLSNILLDRDYNPKLCDFGIAR
 .           |. |. .. |||. . .|..              |  . ...|.  |  | ... | ..| |||.| .||||      ||||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

FYKDDM-----------------ELTRKIGTPIYIAPKVFT------DNHYTKKADVYSYAILLYELSEKTRPFKKPEGLSVAEIIQ--KVVQA------
   |.|                 . .  .||| . || | .      |..|. |.|..|  ... |. .   |. .   ...   |.  ...|.      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---GQRPQFTDVTP-------------------IPLRKLIESCWDADPTKRP
   |. |.. | .                     ...  |. | . || |||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRP

Kinase 96044.m00352.AA Dicty4-Unclassified 138-290 39 2.2e-38 129.06 In-house 113-263 (263) Show / Hide
Range on Protein: 138-290
Range on HMM: 113-263/263
Sequence Identity: 39% (60 aa)

KIAMGIAFGMQHVHMLGILHRDLKLSNILLDRDYNPKLCDFGIARFYKDDMELTRKIGTPIYIAPKVFTDNHYTKKADVYSYAILLYELSEKTRPFKKPE
|.|. || |||| |   . |||.| ||||.|...| |  ||||.|       .|   |||   .| .     |. |.||||||..||||     |.   |
KYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGDEPYQ--E

GLSVAEIIQKVVQAGQRPQFTDVTPIPLRKLIESCWDADPTKRPEFSYIYEQF
  |. ..   |   . ||.  |  .  ..|||  ||  || ||| .  | .  
IQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL

Kinase 96044.m00352.AA TK 35-290 15 4.7e-38 124.62 In-house 1-486 (486) Show / Hide
Range on Protein: 35-290
Range on HMM: 1-486/486
Sequence Identity: 15% (76 aa)

IEILDSIGEGGFA---SVYKG----IDRRNGN---------------------FVAIKQVFE-SRVYVDNFRR--------------FSNEIRTMA--RC
|.... .||| |     ||||    ... ||.                      ||.|.. | .    . |.               . .|.  |    .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HCCCLTKLIG-FTTT------------KPYSIITEFEEN----LSLDSQLTNKKK---------------------------------------------
|.  . .|.|  |              .|. |..|. ..     ||.. | ....                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------------------------ADIFTGTRLSKIAMGIAFGMQHVHML------GILHRDLKLSNILLDRDYN-----------PKLCDFGIAR
                             ...|  .|  ... || ||.. | .      .. ||||   |.|......            |..||| .|
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----FYKDDM---ELTRKI------------------------GTPI---YIAPKVFTDNH---------YTKKADVYSYAILLYELSE--KTRPFK-K
       .|.    . .||                         |. .   . || ...|..         .| | ||.|. .|..|.    .. .    
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

PE------GLSVAEIIQKVVQAGQR--------------PQFTDVTP-------------IPLRKLIESCWDADPTKRPEFSYIYEQF
.       | ...|....... |.               ||  . ..               .  |. .||..|| .|| || ..||.
SNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase 96044.m00352.AA ULK 35-247 20 2.9e-35 122.58 In-house 1-269 (324) Show / Hide
Range on Protein: 35-247
Range on HMM: 1-269/324
Sequence Identity: 20% (54 aa)

IEILDSIGEGGFA-SVYKGIDRRN---GNFVAIKQVF---ESRVYVDN-----FRRFSNEIRTMARCH---CCC--LTKLIGFTTTK---PYSIITEFEE
... . .|.| |.  ||||.. ..   . .||.|..     .  . ..        . |||..|   .   .      ||. .. |.    . ||.|. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NLSLDSQLTNKKKA------DIFTGTRLSKIAMGIAFGMQHVHMLGILHRDLKLSNILLDRDYN------------PKLCDFGIARFYKDDMELTRKI--
   |.. . ..||        ...     .. . |. |... |  .| |||.|..|||.  .               |..||| |..  ....   ..  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GTPIYIAPKVFTDN----HYT-KKADVYSYAILLYELSEKTRPFKKPEGLSVA----EIIQK
        |||.| || .. ..    .|. .|.|..|  ...||.     ||...   .      . |..
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINN

Kinase 96044.m00352.AA Pkinase_Tyr 35-290 28 1.4e-31 107.59 Pfam 1-270 (270) Show / Hide
Range on Protein: 35-290
Range on HMM: 1-270/270
Sequence Identity: 28% (78 aa)

IEILDSIGEGGFASVYKGIDR----RNGNFVAIKQVFESRVYVDN--FRRFSNEIRTMARC-HCCCLTKLIGFTT--TKP--YSIITEFEENLSLDSQLT
|...  .||| | .||||. .     ..  ||.| .       ..   . | .|...|    |.  . .|.|  |   .|  . |..|. .. .|.. | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

NK-KKADIFTGTRLSKIAMGIAFGMQHVHMLGILHRDLKLSNILLDRDYNPKLCDFGIARFY-KDDMELTRKIG---TPI-YIAPKVFTDNHYTKKADVY
..    . .|  .| .... || ||.. .  .. ||||   |.|....   | |||| ||   .||   .|| |    ||   || .. .. .| | ||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SYAILLYELSEKT-RPFKKPE--GLSVAEIIQKVVQAGQRPQFTDVTPIPLRKLIESCWDADPTKRPEFSYIYEQF
|. .|..|.      |    .  |.| .|..... . |.|    . .| .. .|. .||..|| .|| ||.|.||.
SFGVLMWEIFTYGEQP----TYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase 96044.m00352.AA Dicty4 35-64 50 2e-07 21.04 In-house 1-28 (277) Show / Hide
Range on Protein: 35-64
Range on HMM: 1-28/277
Sequence Identity: 50% (15 aa)

IEILDSIGEGGFASVYKGIDRRNGNFVAIK
| | . ||.|.|..||||. |  |  ||.|
INIEQRIGKGSFGEVYKGTWR--GKEVAVK

Kinase 96044.m00352.AA Dicty4-Unclassified 35-53 47 6.2e-05 12.79 In-house 1-19 (263) Show / Hide
Range on Protein: 35-53
Range on HMM: 1-19/263
Sequence Identity: 47% (9 aa)

IEILDSIGEGGFASVYKGI
| |.  ||.| |. |.||.
IQIDQFIGKGHFSKVHKGN