Gene 86188.m00116 (T.vaginalis)

86188.m00116

Species: T.vaginalis
Alias: 86188.m00116, TvagK0190
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
86188.m00116.AA Protein None 321 None Fasta, JSON
86188.m00116.kin_dom Protein Kinase Domain None 244 None Fasta, JSON

Protein domain

Protein domains of 86188.m00116.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 86188.m00116.AA S_TKc 14-257 26 1e-75 258.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-231/231
Sequence Identity: 26% (70 aa)

IEYISTIAEGAYGKIFLVYSKKLQANFALKKIPEKDFSESEVELMKELSHPNVIKMIQIYRFSSYVYLLMEYCPF---DLHKFLEKHEQ------VNPDQ
 | . .| .||.|| .... || .  .|.|.|.  .  ..|....|.  |||..|.. ...  ...|. ||||.    ||.....|.         .. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

LNRLCHDILISIKALHDQNIAHSDIKPSNFLLDKSGHVKVCDFGFSSKYDVNSESQTHHGTLFFMAPEIFKKQKYNPLKADIWAIGVTFYYMATHSFPFF
  .... |.  .. .|...| | |.||.| |||.  |.|.||||.. ..       |  ||...||||..   .|.. |.|.|..|...| |..   || 
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP

STNILQFIKIVNNGLYPQYKIPNIALQMVISRCLEINPDNRPTIDELLR-------MPYF
  .. . .|..              .   |..||. .|..|||. |.|.       .|.|
--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 86188.m00116.AA Pkinase 14-257 24 2.4e-70 244.83 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-293/293
Sequence Identity: 24% (72 aa)

IEYISTIAEGAYGKIFLVYSKKLQANFALKKIPEKDFSE---------SEVELMKELSHPNVIKMIQIYRFSSYVYLLMEYCPF-----DLHKFLE--KH
.. ...| .|..|. .. . |. .  .|.|.|. .. ..         ||...||.|.|||..... ... ....|. ||||.      ||. ...  .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

EQV--NPDQLNRLCHDILISIKALHDQNIAHSDIKPSNFLLDKSGHV----KVCDFGFSSK--YDVNSESQTHHGTLFFMAPEIFKKQKYNPLKADIWAI
  .   .... . .  ||  .. .|...| | |.||.|.|.|. ||.    |.||||.. .  |  ||  .|  ||...||||. ....| . |.|.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVTFYYMATHSFPFFST----NILQFIKIVNNGLYPQYKIPN------------------------IALQMVISRCLEINPDNRPTIDELLRMPYF
|...|.|..  .|| .     | .  ...... ..|... .                          ... .|..||. .|  |||....|  |.|
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 86188.m00116.AA CAMK 19-257 18 4.6e-68 218.18 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-257
Range on HMM: 1-425/425
Sequence Identity: 18% (79 aa)

TIAEGAYGKIFLVYSKKLQ------------ANFALKKIP---------------------------------EKDFSESEVELMKELS-------HPNV
|. .|..|| .|.. |. .              .| | |.                                  ... ..|.|.|| |.       |||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKMIQIYR------------FSSY--------VYLLM---EYCP-----FDLHKFLEKHEQ---------------VNPDQLNRLCHDILISIKALHDQN
||....|             . |.        .|. |   |||.     .||  .. .|..               .. ..  |. . |.  .. .|..|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IAHSDIKPSNFLLDKS-----------------GHVKVCDFGFSSKYDV------------------------NSESQTHHGTLFFMA-PEIFKK-----
|.| |.|| | |||..                 . .|..||||. |.|                         .   .|  ||. .|| ||....     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------QKYNPLKADIWAIGVTFYYMATHSFPFFST-------------NILQFIKIVNNGLY--PQYKIPNIA----------------------LQ
        ..| . |.|.|..||  | | .  .|| .              |. .  . . .| |  | .....|                        .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

MVISRCLEINPDNRPTIDELLRMPYF
  |...|. .|..|.||.. |. | .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 86188.m00116.AA CAMKL 15-257 26 8.8e-62 195.88 In-house 2-297 (297) Show / Hide 
Range on Protein: 15-257
Range on HMM: 2-297/297
Sequence Identity: 26% (78 aa)

EYISTIAEGAYGKIFLVYSKKL-QANFALKKIP-----EKDFSES---------------EVELMKELS---HPNVIKMIQIYRFSSY------VYLLME
. . |. .|..||  |   ... .   | | |      .......               |...|| |.   |||.||. ...  ...      .|| ||
RIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVME

YCP---FDLHKFLEKHEQ----VNPDQLNRLCHDILISIKALHDQNIAHSDIKPSNFLLDKSG--HVKVCDFGFSSKYD-V----NSESQTHHGTLFFMA
||.    ||. ...||.       ...  |.   |.  .. .|...|.| |||| | |||..|   .|..||||| .|. .    .    |. |.. .||
YCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMA

PEIFKK--QKYNPLKADIWAIGVTFYYMATHSFPF----------FSTNILQFIKIVNNGLYPQYKIPNIALQMVISRCLEINPDNRPTIDELLRMPYF
||||..  ..|.  |.|||..||. | | .  .||          . .  |  ....  . .| .. .   ..  |.. |. ||. ||||..... | .
PEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 86188.m00116.AA ULK 14-257 23 1.3e-54 187.72 In-house 1-329 (329) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-329/329
Sequence Identity: 23% (78 aa)

IEYISTIAEGAYGKIFLVYSKKL----QANFALKKIP---EKDFS------------ESEVELMKELS--------HPNVIKMIQIYRFS--SYVYLLME
.. .  . .|..|| .  . ||     .  .| |.|.   .. ..            ..|...||.|         |||..|.. ... |   ..|. ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPF-DLHKFLEKHEQ----------VNPDQLNRLCHDILISIKALHDQNIAHSDIKPSNFLLDKS------------GHVKVCDFGFSSKYDVN----S
||.  || ....|.             . ..    ...||   |.||..|| | ||||.| |...             |..|..||||. . | .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

ESQTHH------GTLFFMAPEIFK----KQKYNPLKADIWAIGVTFYYMATHSFP----FFSTNILQFIKIVNNGL------------YPQY-KIPNIAL
  .|        ||  .|||.|..    ...|.  |.||| .|. ||.| .   |    |....... .| .||..            .|.. ..|.|  
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

QM--VISRCLEINPDNRPTIDELLRMPYF
..   |.|.|..... | ...||. .| |
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 86188.m00116.AA ULK 14-257 23 6.8e-54 185.36 In-house 1-324 (324) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-324/324
Sequence Identity: 23% (77 aa)

IEYISTIAEGAYG-KIFLVYSKKL---QANFALKKIP---EKDFSE------------SEVELMKELS---HPN--VIKMIQIYRFS--SYVYLLMEYCP
.. .  . .|..| | .  . ||    .  .| |.|.    ....             .|...||.|    |||  ..|.. ... |   ..|. ||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

F-DLHKFLEKHEQ---------VNPDQLNRLCHDILISIKALHDQNIAHSDIKPSNFLLDK------------SGHVKVCDFGFSSKYDVNSESQTHH--
  || ....|.            . ..    ...|.   |.||..|| | ||||.| |. .            .|..|..||||. . | |...|.    
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GTLFFMAPEIFK----KQKYNPLKADIWAIGVTFYYMATHSFP----FFSTNILQFIKIVNN----------GLYPQY---KIPNI--ALQM
        ||  .|||.|..    ...|.  |.||| .|. ||.| . . |    | ....   .| .||             . .   |.|.|   .. 
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

VISRCLEINPDNRPTIDELLRMPYF
 |.|.|..... | ...|.. .| |
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 86188.m00116.AA MARK 15-257 31 2.8e-53 172.57 In-house 2-262 (262) Show / Hide 
Range on Protein: 15-257
Range on HMM: 2-262/262
Sequence Identity: 31% (82 aa)

EYISTIAEGAYGKIFLVYSKKLQANFALKKIP-------EK-DFSESEVELMKELSHPNVIKMIQIYR--FSSY-VYLLMEYCP-FDLHKFLEKH--EQV
. . || .|.|.|  |. .|. . ..|.| ..       ..    ..|.|.|| |.|||.||. ..     ..  .|| |||..  .|. ....|     
KMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRL

NPDQLNRLCHDILISIKALHDQNIAHSDIKPSNFLLDKSG--HVKVCDFGFSSKYDVNSESQTHHGTLFFMAPEIFKKQKYNPLKADIWAIGVTFYYMAT
  .   |... |.  .. .|..||.| |||| | |.|. |   .| .||||| .   ..   |. ||. .||||||.|..|.  |.|||. ||  |.| .
HEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVC

HSFPFFSTN--ILQFIKIVNNGLYP-QYKIPNIALQMVISRCLEINPDNRPTIDELLRMPYF
 .|||  ..  . .  | ...| |.  ....  . .. |.| | .||. ||||.|... | .
GYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNL-IQRLLTVNPEERPTIEEIMKHPWM
Kinase 86188.m00116.AA Ciliate-E2 14-257 20 2.5e-50 170.94 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-365/365
Sequence Identity: 20% (76 aa)

IEYISTIAEGAYGKIFLV---YSKKLQA--------------------NFALKKIPEK--DFSESEVELMK----------------ELSHPNVIKMIQI
.. |  | .|..|.....     .|..|                     .|.| . ..   . ..|  .|.                .|.|||.|||.  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YR--FSSYVYLLMEYCPF-DLHKFLEKHEQVNPDQLN-------RLCHDI---LIS----------------IKALHDQN-IAHSDIKPSNFLLDKSGHV
.     ...|| ||||   || ...... .  . ...       . . .|   ...                .. || .| | | ||||.| |.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KVCDFGFSSKYDVNSESQTH--------------------------------HGTLFFMAPEIFKKQKY--------NPLKADIWAIGVTFYYMATHSFP
|..|||.| ||| ... .||                                 ||. .|||||....||           |.|||..||..|.| .  .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FFSTNILQFIKIVNNGLYPQ-----------------YKIPNIALQMVISR----CLEINPDNRPT-IDELLRMPYF
|       ...| .. .  .                 .|      .  |..    .|. .|..|.| ....|  |.|
F-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 86188.m00116.AA Ciliate-E2-Unclassified 14-257 22 1e-47 163.55 In-house 1-352 (352) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-352/352
Sequence Identity: 22% (80 aa)

IEYISTIAEGAYGKIFLVYSKK-----------LQANFALKKIPEKD---FSESEVELMK----------------ELSHPNVIKMIQIYRFSSYVYLLM
 . | .| .|..||..... ||            . ... |.| .||   ... |.. .|                 . ||...||. . .   ..|. |
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYCP-FDLHKFLEKHEQ-----------------VNPDQLN-----RLCHDILISIKALHDQN-IAHSDIKPSNFLLDKSG---HVKVCDFGFSSKYDVN
|||.  ||.....| ..                 .   |       ...  ||  .. || .| | | ||||.| |.|..|   ..|..|||.|.||. |
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

----------------SESQTHHGTLFFM----APEIFKKQKYNP---LKADIWAIGVTFYYMATHSFPFFSTNILQ----------------FIKIVNN
                 ...|  ||. .|    |||....|.|.     |.|||. || .|.| .  .||...|  |                .... ..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

G--LYPQYKI----PNIALQM--VIS----RCLEINPDNRPTIDELLRMPYF
.   .| ..      ..  .    |.    ..|. ||..|.|....|  |.|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 86188.m00116.AA CMGC 14-216 17 9.9e-44 141.0 In-house 1-368 (513) Show / Hide 
Range on Protein: 14-216
Range on HMM: 1-368/513
Sequence Identity: 17% (63 aa)

IEYISTIAEGAYGKIFLVYSKKLQAN--------------FALKKIP-EKDFSE----------------SEVELMKELS-----------------HPN
 | |. | ||.||. .  . |. . .               |.|||  .. . |                 |....|.|.                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VIKMIQIYRFSS-----------------YVYLLMEYCPFDLHKFLEKHE---------QVNPDQ------------LNRLC------HDILISIK--AL
..|.. |....                  ..|| .||.. ||.......            .. .               .       . || ..|   .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HDQN--IAHSDIKPSNFLLDKS--------------------GHVKVCDFGFSSKYDVNSE----------------------SQTHHGTLFFMAPEIFK
| ..  | | |.||.| |...                     |..|.||||.. .|...|.                        .   |..  ||||  
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

KQKYNP---------LKADIWAIGVTFYYMATH-------SFPFFS--TN-----------ILQFIKIVN
  |.            . |.|..|  |. | |          |.|   ..           | |  ||..
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFK
Kinase 86188.m00116.AA STE 14-257 20 8.4e-43 148.52 In-house 1-359 (359) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-359/359
Sequence Identity: 20% (75 aa)

IEYISTIAEGAYGKIFLVYSK------KLQAN---------FALKKIP----------------------EKDFSESEVELMKELS--HPNVIKMIQIYR
 | |. | .||.|. .. . .      | . .         .| |...                      |..  . |...||...  |||..| .  | 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

FS-------SYVYLLMEYCPF-DLHKFLE---KHEQVNP-----------DQLNRLCHDILIS-IKALHDQNIAHSDIKPSNFLLDKSGHVKVCDFGFSS
         ..... |||..   | ....   .. . ..           .|. . |..||    . ||...| | ||||.| ||     || ||||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

KYD-----------------VNSESQTHHGTLFFMAPEIFKK------QKYNPLKADIWAIGVTFYYMATHSFPFFSTNILQ--FIKIVNNGLY------
. .                   ....|  ||  .||||. ..      ..|.  |.||| .| |   |||   |..  . ..  | .. |.. .      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

-----PQYKIPN----------------------IALQMVISRCLEINPDNRPTIDELLR--MPYF
     |  ..|.                        ..  |..||...|..||| ..||.   | .
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 86188.m00116.AA TKL 20-255 17 6.4e-36 125.65 In-house 1-364 (364) Show / Hide 
Range on Protein: 20-255
Range on HMM: 1-364/364
Sequence Identity: 17% (64 aa)

IAEGAYGKIFLVYSKKLQ--------ANFALKKIPEK--------------------------------DFSESEVELMKELSHPNVIKMIQIYRFSSY-
| .|..|...  . .              | ||....                                .| | |. .|. |.|||..... .   ... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------VYLLMEYCPF-D-LHKFLEKHEQVNPDQLNRLCHDILISIKALHDQN--------IAHSDIKPSNFLLDKSGH--------------V
             .. |||||  . || ..       ..|. |...||   .  || .|        |.| |.|..| |.|. ..              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KVCDFGFSSKYDVNSESQTH--------------------HGTLFFMAPEIFKKQKYNP---------------LKADIWAIGVTFYYMATHSFPFF-ST
|.||||.|   . .....                       ||. .||||....| ...                |.|... |. .. ..|   |..   
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

NI---------LQFIKIVNNGLYPQYK-----------IPNI--ALQMVISRCLEINPDNRPTIDELLRMP
..         . |......|| |  .            |..   .   . .| . .|..||. .|.|   
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 86188.m00116.AA TyrKc 14-257 21 6.6e-16 34.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

IEYISTIAEGAYGKIFL-VYSKKLQANFALKKIP---EKDFSESEVELMKEL--SHPNVIKMIQIYRFS-------SYVYLLMEYCPF-DLHKFLEKHEQ
|. . .. |||.|.... ...     . | |..    ..||  .| ..|..|  .|||..... . . .         ....|||.|  ||...| ||. 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDAREDF-MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-VNPDQLNRLCHDILISIKALHDQNIAHSDIKPSNFLLDKSGHVKVCDFGFSSKYDVN------SESQT------HH--GTLFFMAPEIFKKQKYNPLKA
 .....|   |..|      ||..|. | |.   | |... ..||..||| | . .        ..  .       .    .  |||| ... |... | 
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT-KS

DIWAIGVTFYYMATHSFPFFS------TNILQFIKIVNNG-LYPQYKI--------PNIALQMVISRCLEINPDNRPTIDELLRMPYF
|.|. ||. . . |   .  .       .  . |. | .|   || .            .. .....| . .|..|||  |.    .|
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 86188.m00116.AA CMGC 234-257 37 2.2e-09 26.0 In-house 490-513 (513) Show / Hide 
Range on Protein: 234-257
Range on HMM: 490-513/513
Sequence Identity: 37% (9 aa)

ISRCLEINPDNRPTIDELLRMPYF
....|...||.|.|... |..|||
LKKMLQYDPDKRITAEQALQHPYF
Kinase 86188.m00116.AA Pkinase_Tyr 14-112 25 2.2e-08 29.0 Pfam 1-120 (270) Show / Hide 
Range on Protein: 14-112
Range on HMM: 1-120/270
Sequence Identity: 25% (31 aa)

IEYISTIAEGAYGKIFLVYSK----KLQANFALKKIPE---------KDFSESEVELMKEL-SHPNVIKMIQIYR-FSSY--VYLLMEYCPF-DLHKFLE
|. . .. |||.|.... . |    . .   | |...|         .|| . |...||.| .|||..... .    .    .|. |||.|  ||...| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KH----EQVNPDQLNRLCHDI
||    ..... .|   |..|
KHREDKQPLTMKDLLQMCWQI
Kinase 86188.m00116.AA Pkinase_Tyr 135-192 29 0.359146 4.59 Pfam 143-203 (270) Show / Hide 
Range on Protein: 135-192
Range on HMM: 143-203/270
Sequence Identity: 29% (18 aa)

LLDKSGHVKVCDFGFSSKYDVNSES-QTHHGTLF---FMAPEIFKKQKYNPLKADIWAIGVT
|......||.|||| .      ..  ....|. .    |||| ..  |..  | |.|. ||.
LVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFT-TKSDVWSFGVL
Kinase 86188.m00116.AA Pkinase_Tyr 230-254 24 4.012393 1.04 Pfam 245-269 (270) Show / Hide 
Range on Protein: 230-254
Range on HMM: 245-269/270
Sequence Identity: 24% (6 aa)

LQMVISRCLEINPDNRPTIDELLRM
. ... .| . .|..|||  |....
IYDLMKQCWHYDPEDRPTFSEIHEQ