Gene 81399.m00051 (T.vaginalis)

81399.m00051

Species: T.vaginalis
Alias: TvagK0796, 81399.m00051
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: LKB

Sequence

Name Sequence Type Origin Length Description Download
81399.m00051.AA Protein None 371 None Fasta, JSON
81399.m00051.kin_dom Protein Kinase Domain None 268 None Fasta, JSON

Protein domain

Protein domains of 81399.m00051.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 81399.m00051.AA S_TKc 32-299 27 2.7e-71 244.07 SMART 1-231 (231) Show / Hide 
Range on Protein: 32-299
Range on HMM: 1-231/231
Sequence Identity: 27% (77 aa)

IHILKTIGSGSFGRVYLGCQMETKKYYAVKRASYKDLNHMCNGVGQLEREIRMLQTFNHNNILKLYEVYQATEKPYVYMIMEYADC--GCLEDKIDGSPS
 .||..||.|.||.||..   .|....|.|. .            ...|||..|.  .| || |||.|.|     ..||.|||.|   | | | |.  ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR

P-----YKFEDILSIIKQVAGALTYMHSMGIVHQDIKPSNILLCSDGRILLSDFGIGHRFQSAAMVVGSPAYQAPEVLDDYEEESFDSDGEAEDYADG-P
.     .   .. ....|.. || |.||.||.| |.||.||||..  .| ..|||.  ..     ..|.| | |||||                  .. .
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVL----------------GYGKCK

IKEDVWALGVTFYQLLFSKLPWVGENLYEIVHLIKTTPLVIPEGTDPEVVKLLHMMLNKDPMQRISMKDLTT-------FPLI
.  |.|..|...| .|  . |.   ..... ..|.          .||.  ..  .|.||| .|..  .. .        | .
C--DWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 81399.m00051.AA Pkinase 32-299 25 3.3e-63 221.12 Pfam 1-293 (293) Show / Hide 
Range on Protein: 32-299
Range on HMM: 1-293/293
Sequence Identity: 25% (80 aa)

IHILKTIGSGSFGRVYLGCQMETKKYYAVKRASYKDLNHMCNGVGQLEREIRMLQTFNHNNILKLYEVYQATEKPYVYMIMEYADCG----CLEDKID-G
.||...|||||||.||...   | | .|||. .... .. ..    . .||.... .|| ||..||....   |...||.|||...|     | | |   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

SPSPY--KFEDILSIIKQVAGALTYMHSMGIVHQDIKPSNILLCSDGRI----LLSDFGIG----HRFQSAAMVVGSPAYQAPEVLDDYEEESFDSDGEA
.  ..    ... ....|.. .| |.|||||.| |.||.|||. ..| |     ..|||.     .  .|.  ..|.| | ||||.              
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIR-------------

EDYADGPIKEDVWALGVTFYQLLFSKLPWVGE------NLYEIVHLIKTTPLVIPEGTD---------------------PEVVKLLHMMLNKDPMQRIS
 .. . . | |.|..|...|..|. ..|. |.      . .... .|. .||  .. ..                     .|  ...  .|.||| .|..
-GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT

MKDLTTFPLI
 ...   | .
AEQILQHPWF
Kinase 81399.m00051.AA CAMK 37-299 20 5.1e-63 201.62 In-house 1-425 (425) Show / Hide 
Range on Protein: 37-299
Range on HMM: 1-425/425
Sequence Identity: 20% (87 aa)

TIGSGSFGRVYLGCQMETK------------KYYAVKRASYKDLN------------------------HMCNGVGQLEREIRMLQT-------FNHNNI
|.|.|||| |.|... .|.            . .|.|  . | |                         .  .   ...|||.....        .| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LKLYEVYQ------------ATEKP------YVYMIM---EYADCGCL----EDKIDGSPS--------------PYKFEDILSIIKQVAGALTYMHSMG
.||||||.              .|.      ..||.|   ||.. |.|     |.|   ..               .. ..   ...|.. |. |.||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHQDIKPSNILLCSD-----------------GRILLSDFGIGHRFQS---------------------------AAMVVGSPAYQA-PEVLDDYEEES
||| |.|| ||||...                 . | ..|||   .|..                              ..|.|.| | ||||      .
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

FDSDGEA----EDYADGPIKEDVWALGVTFYQLLFSKLPWVGE-------------NLYEIVHLIKTTPLV-IPEGTDP---------------------
.   . |    ..| . ..  |.|..||  | .|  ..|. |.             |.||. . |..     .|.  .|                     
MQ--N-ATDEEKPYYGPKC--DMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFV

--EVVKLLHMMLNKDPMQRISMKDLTTFPLI
  |.  |.  ||..|| .|.. ..    | .
SQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 81399.m00051.AA Ciliate-E2 32-299 21 1e-54 186.27 In-house 1-365 (365) Show / Hide 
Range on Protein: 32-299
Range on HMM: 1-365/365
Sequence Identity: 21% (84 aa)

IHILKTIGSGSFGRVYLGCQMETK-----------------------KYYAVKRASYKDLNHMCNGVGQLE---------REIRMLQTFNHNNILKLYEV
. ..| ||.|.|| ||.... ...                       |.||.|. . ...... .   ..           | ..|.. ||.||.|.||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YQATEKPYVYMIMEYADCGCLEDKI------------DGSPSPYKFEDILSIIKQVAG---------------ALTYMHSMG-IVHQDIKPSNILLCSDG
.| . . ..|..|||.. | |.| |                 ... . |. |.||..                || |.|| . |.| ||||.|||.    
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

RILLSDFGIGHRFQ---------SAAM--------------------------VVGSPAYQAPEVLD--DYEEESFDSDGEAEDYADGPIKEDVWALGVT
 | ..|||.  ...         . .                           ..|.| |.|||.|   .|. .        ..  .   | |.|.|||.
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ--------QKQKGYDYKCDIWSLGVI

FYQLLFSKLPWVGENLYEIVHLIKTTPLVIP------------------EGTDPEVVKLLHM----MLNKDPMQRIS-MKDLTTFPLI
.|..|| |.|.           ||  .. .|                  .  ..|.  |.      ||.||| .||. ....   | .
LYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 81399.m00051.AA STE 32-299 21 8.8e-49 168.39 In-house 1-359 (359) Show / Hide 
Range on Protein: 32-299
Range on HMM: 1-359/359
Sequence Identity: 21% (81 aa)

IHILKTIGSGSFGRVYLGCQME---------------TKKYYAVKRASYKDLNHMCNG--------------VGQLEREIRMLQTFN--HNNILKLYEVY
  ... ||.|.|| ||... ..               |....|.|. .... | .                 . |...||.... .|  | || | |  |
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

Q-----ATEKPYVYMIMEYADCGCLEDKID-----GSPSPYKF-------EDIL-SIIKQVAGA-LTYMHSMGIVHQDIKPSNILLCSDGRILLSDFGIG
        .. .....||| | |.|.| |.     | | . ..       |...  |..|.  . | | ||..|.| ||||.||||     . |.|||. 
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

HRFQS--------------------AAMVVGSPAYQAPEVLDD----YEEESFDSDGEAEDYADGPI--KEDVWALGVTFYQLLFSKLPWVG-ENLYEIV
 ....                       .||.| . ||||..     .               |..   | |.| || |   ..  | ||    ... . 
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGR---------------DKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMF

HLIKT---------------TPLVIPEGTD-------------------PEVVKLLHMMLNKDPMQRISMKDLTT--FPLI
. ..                .|  .|. ..                   ||    .   |.||| .| . ..|     | |
MIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 81399.m00051.AA CAMKK 33-299 22 5.8e-47 146.83 In-house 2-396 (396) Show / Hide 
Range on Protein: 33-299
Range on HMM: 2-396/396
Sequence Identity: 22% (88 aa)

HILKTIGSGSFGRVYLGCQMET-KKYYAVKRASY----KDLNH----------------------MCNGVGQLEREIRMLQTFNHNNILKLYEVYQATEK
...|.||.|.|| | |    .. .|.||.|  .     | |                        | |.  ....||  .   || || ||||| . .. 
ELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDPQN

PYVYMI-MEYADCGCLEDKI-DGS-----------------------PSPYKFED---------------------ILSIIKQVAGALTYMH-SMG----
 ..||. |||.. | . ..  .                         .|   ..                        ..  ... .| |.| . .    
DKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKACSY

---------------IVHQDIKPSNILLCSDG---RILLSDFGIGHRF-QSAAM--------------VVGSPAYQAPEVLDDYEEESFDSDG---EAED
               |.| ||||.|||. ..|   .. ..|||. | | .. .                .| ||..|||.... |.. .. .|     . 
IIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSK-ENQKENYNGYKYRFRF

YADGPIKEDVWALGVTFYQLLFSKLPWVGENLYEIVH---LIKTTPLVIPE-------------GTDPEVVKLLHMMLNKDPMQRISMKDLTTFPLI
  .|. . |.||||||.| ..| |.| ...|| .. |    ||  |.. ||                .. . |.  ||.|.|..||. ... . | .
IYCGK-AADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPWV
Kinase 81399.m00051.AA Ciliate-E2-Unclassified 32-299 21 4e-46 158.0 In-house 1-352 (352) Show / Hide 
Range on Protein: 32-299
Range on HMM: 1-352/352
Sequence Identity: 21% (80 aa)

IHILKTIGSGSFGRVYLGCQMETKKYYAVKRASYKDLNH---MCNGVGQLEREIRMLQTFN-----------------HNNILKLYEVYQATEKPYVYMI
 .|.|.||.|.|| ||.  . ..|.||| | .. .  ..   . |   .. .|.  ..  .                 |.........|. . | ..|..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYADCGCLEDKIDGSPS----------------PYKFEDIL-----SIIKQVAGALTYMHSMG-IVHQDIKPSNILLCSDG---RILLSDFGIGH----
|||.. | |.. |  ...                    . ..      ...|.  .| |.|. . |.| ||||.|||. ..|   .| ..||||      
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------RFQSAAMVVGSPAYQ----APEVLDD--YEEESFDSDGEAEDYADGPIKEDVWALGVTFYQLLFSKLPWVGENLYE---------
               ..| .  ..|.| |.    |||||.   |.....             .| |.|.||| .|..|| ..|  ..| ..         
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA-------------YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI

-------IVHLIKTTPLVIPE--------GTDPEVV----KLLHMMLNKDPMQRISMKDLTTFPLI
       .   ||  .. .|.        . .||.     .||. ||.|.| .||.....   |..
NNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 81399.m00051.AA CAMKL 34-202 32 1.3e-45 143.46 In-house 3-205 (297) Show / Hide 
Range on Protein: 34-202
Range on HMM: 3-205/297
Sequence Identity: 32% (65 aa)

ILKTIGSGSFGRVYLGCQ-METKKYYAVKRASYKDLNHMCNGVGQ-----------LEREIRMLQTFN---HNNILKLYEVYQATEK----PYVYMIMEY
|.||.| |||| | |..  . |.. .|.|    | ..  ..               ..|||. .. .|   | || |||||..  |.     ..|..|||
IGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEY

ADCGC--LEDKIDGSP---SPYKFEDILSIIKQVAGALTYMHSMGIVHQDIKPSNILLCSDG--RILLSDFGIG---HR-----FQSAAMVVGSPAYQAP
.. |   | |.|.  .    . . ..   . .|.  |. |.||.|||| |||| |||| ..|   | ..||| .    .      |   .  |||.|.||
CSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAP

EVL
|..
EIF
Kinase 81399.m00051.AA CAMK-Unique 32-244 23 1.3e-43 141.71 In-house 1-292 (363) Show / Hide 
Range on Protein: 32-244
Range on HMM: 1-292/363
Sequence Identity: 23% (69 aa)

IHILKTIGSGSFGRVYLGCQMETKKYYAVKRASYKDLNHMCNGV----------------GQLEREIRMLQTFNHNNILKLYEV----YQATEK------
.  .. ||.|.|| || .   ||.| .|.|.   ..     . .                 .|.||.. ... .|.||.|||..    ..  ..      
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

-------PYVYMIMEYADCGCLEDKIDG-------------------SPSPYKF--EDILSIIKQVAGALTYMHSMGIVHQDIKPSNILLCSDGR-----
       || |..|||...|.| |.|.                    .  ..     |...|. ... |. |||| .||| |.|. ||..|. .      
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-----------ILLSDFGIGHRFQSAAMV------VGSPAYQAPEVLDDYEEESFDSD--GEAEDYADGPI--KEDVWALGVTFYQLLFSKLP
           | |.|||.   ...  |       .|.| | |||.       ..  |  ... .| |..     | |.|||. | .|. ..|
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCY-DQQCSPASDIWSLGVIMYYMLCGCPP
Kinase 81399.m00051.AA Ciliate-E2a 33-202 33 9.9e-41 117.63 In-house 2-182 (275) Show / Hide 
Range on Protein: 33-202
Range on HMM: 2-182/275
Sequence Identity: 33% (61 aa)

HILKTIGSGSFGRVYLGCQMETKKYYAVKRASYKDLNHMCNGVGQLEREIRMLQTFNHNNILKLYEVYQATEKPYVYMIMEYADCGCLEDKIDGSPSPYK
 ..| ||.|.||.|||  . .|.| .|.|  .   ..   .|  ....||  ... .| ||.||||||.     . |..||| . | |.|||  . .  .
KFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDEN--NYYLVMEYCEGGELYDKIKQCKRFFE

F-EDILSIIKQVA-GALTYMHSMGIVHQDIKPSNILLC---SDG----RILLSDFGIGHRF---QS--AAMVVGSPAYQAPEVL
. ..| .|..|    .| |||. .|.| |.|| |||.    ...     | ..||| . ..   .       .|.| | |||||
EIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVL
Kinase 81399.m00051.AA ULK 32-205 25 1.2e-34 120.34 In-house 1-228 (324) Show / Hide 
Range on Protein: 32-205
Range on HMM: 1-228/324
Sequence Identity: 25% (58 aa)

IHILKTIGSGSFG-RVYLGCQMET---KKYYAVKRASYKDLNHMCNGVG------QLEREIRMLQTFN---HNN--ILKLYEVYQATEKPYVYMIMEYAD
. . . .|.||||  || |  ..|   ..|.|.|  . | .|   |         .|..||. .....   |.|  | |||.... .   ..|.|||| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

CGCLEDKID---GSPSPY---KFED---ILSIIKQVAGALTYMHSMGIVHQDIKPSNILLCSD------------GRILLSDFGIGHRFQ---SAAMVV-
.| ||. |    ..|      |.     .....|| . .. ..|...|.| ||||.|||.  .            |.. ..||| .  ..    ....  
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

---------GSPAYQAPEVLD------DY
         |.| | ||..|       .|
TCVNEKRIKGTPLYMAPQILQGQGEQKPY
Kinase 81399.m00051.AA ULK 32-205 25 6e-33 112.38 In-house 1-232 (329) Show / Hide 
Range on Protein: 32-205
Range on HMM: 1-232/329
Sequence Identity: 25% (58 aa)

IHILKTIGSGSFGRVYLGCQMETK----KYYAVKRASYKDLNHMCNGVG------QLEREIRMLQTFN----HNN----ILKLYEVYQATEKPYVYMIME
... . .|.||||.|| |  ..||    ...|.|  . . .|   |         .|..||. ... .    |.|    | |||.... .   ..|.|||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YADCGCLEDKID---GSPSPY---KFED---ILSIIKQVAGALTYMHSMGIVHQDIKPSNILLCSD------------GRILLSDFGIGHRFQS------
| . | ||. |    ..| .    |.     .....|| . .. ..|...|.| ||||.|||.  .            |.. ..||| .  ...      
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-AAMVV------GSPAYQAPEVLD------DY
 .   |      |.| | ||..|       .|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPY
Kinase 81399.m00051.AA Pkinase_Tyr 32-179 28 9e-24 81.14 Pfam 1-156 (270) Show / Hide 
Range on Protein: 32-179
Range on HMM: 1-156/270
Sequence Identity: 28% (46 aa)

IHILKTIGSGSFGRVYLGCQM----ETKKYYAVKRASYKDLNHMCNG--VGQLEREIRMLQTF-NHNNILKLYEVYQATEKP-YVYMIMEYADCGCLEDK
|...|..|.|.||.||.|       .||   |||    |. ..|        . ||.... .. .| ||..|| |    ..| ..|..|||. .|.| | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

IDGS---PSPYKFEDILSIIKQVAGALTYMHSMGIVHQDIKPSNILLCSDGRILLSDFG
       . | . .|.|..  |.| .. | .|....| |.   |.|. ... .  .|||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 81399.m00051.AA ULK 227-299 27 3.1e-16 54.17 In-house 234-324 (324) Show / Hide 
Range on Protein: 227-299
Range on HMM: 234-324/324
Sequence Identity: 27% (25 aa)

DVWALGVTFYQLLFSKLP---WVGENLY----EIVH-------LIKTTPLVIP-----EGTDPEVVKLLHMMLNKDPMQRISMKDLTTFPLI
|.| ||. ||..|. | |   |  ...|    . ..       .||..|. .|         ||.  |.  || .|. .|||  ..   |..
DIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 81399.m00051.AA ULK 227-299 29 9.7e-16 51.49 In-house 238-329 (329) Show / Hide 
Range on Protein: 227-299
Range on HMM: 238-329/329
Sequence Identity: 29% (27 aa)

DVWALGVTFYQLLFSKLP---WVGENLY-----EIVHL-------IKTTPLVIP-----EGTDPEVVKLLHMMLNKDPMQRISMKDLTTFPLI
|.| ||. ||..|. | |   |  . .|     . . .       ||..|| .|         ||.  |.  || .|. .|||  .|   |..
DIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 81399.m00051.AA TyrKc 32-297 20 1.7e-13 -4.41 SMART 1-280 (280) Show / Hide 
Range on Protein: 32-297
Range on HMM: 1-280/280
Sequence Identity: 20% (64 aa)

IHILKTIGSGSFGRVYLGCQMETKKYYAVKRAS-YKDLNHMCNGVGQLEREIRMLQTF--NHNNILKLYEVYQATEK-------PYVYMIMEYADCGCLE
|. .|..|.| ||.||.|         |||    ..        .  . ||.|..  .  .| ||..|| |  .|..       . ....|||.. |.| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGV--CTQQGRNFMYIEPLMIVMEYMPHGDLK

DKIDGSPSPYKFEDILSIIKQVAGALTYMHSMGIVHQDIKPSNILLCSDGRILLSDFGIGHRFQSA--------AMVV----GSP-----AYQAPEVLDD
| .  .    . .| ||.  |.|    | ||....| |.   |.|. .....  ||||      .           ..    |.         |||.. .
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-N

YEEESFDSDGEAEDYADGPIKEDVWALGVTFYQLL-FSKLPWVG-----ENLYEIVHLIKTT-PLVIPEG--------TDPEVVKLLHMMLNKDPMQRIS
| . .. |              |||. ||. . .. . . |. |      . .|.....|.   . .|.           .|. ..  .  . || .| .
YGKFTTKS--------------DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPT

MKDLTTFP
....  . 
FSEIHECF
Kinase 81399.m00051.AA CAMKL 227-299 19 3.7e-12 34.94 In-house 218-297 (297) Show / Hide 
Range on Protein: 227-299
Range on HMM: 218-297/297
Sequence Identity: 19% (16 aa)

DVWALGVTFYQLLFSKLPWVGE--------NLYEIVHLIKTTPLVIPEGTDP-EVVKLLHMMLNKDPMQRISMKDLTTFPLI
|.|..||. | ... .||. ..        |  .  . |...   .|   .. ..  |.. ||...|..|......   |  
DIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 81399.m00051.AA Ciliate-E2a 227-293 34 7.7e-07 16.2 In-house 198-269 (275) Show / Hide 
Range on Protein: 227-293
Range on HMM: 198-269/275
Sequence Identity: 34% (25 aa)

DVWALGVTFYQLLFSKLPWVGENLYEIVHLIKTTP--LVIPE---GTDPEVVKLLHMMLNKDPMQRISMKDL
|.| .|| || ||. |.|  |..  ||. ..|     . .||     . |   |.  ||.||| .||. ...
DMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQA