86188.m00109

Species: T.vaginalis
Alias: TvagK0189, 86188.m00109
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
86188.m00109.AA Protein None 287 None Fasta, JSON
86188.m00109.kin_dom Protein Kinase Domain None 240 None Fasta, JSON

Protein domain

Protein domains of 86188.m00109.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 86188.m00109.AA S_TKc 14-260 26 3.7e-64 220.37 SMART 1-231 (231) Show / Hide
Range on Protein: 14-260
Range on HMM: 1-231/231
Sequence Identity: 26% (70 aa)

IKFENVIGVGGYGVLYKVYSEQYKIFFAMKKIPEKLFNKLEVDCLISIDNPNVVNLYKSYKSNGFIYLLLEYCPL---DLDRLLHGNT-------LSNEE
 .. ..|| |..|. ||..    .  .|.|.|.     . |...| . . ||.|.|| .. . ...|. .|||.    || .... .        ..  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

LIKYTYQMILGIKACHENNVAHGDIKPSNFLIDKYGRIKVCDFGLSSYLNQESRMSNFRGTLLFIAPEILKQEEFCPVKADIWALGITIYLMATQRYPYE
  .|.||...... ||.... | |.||.| |.|.  .||.|||||.  |      . | ||. ..|||.|    . . |.|.|..|...| |.. . |..
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP

GHTSEEVLKQIESKKISLKHIKNEVISNIISKCLQIKPNKRATINDLHK---IISKEPCI
  . ....|.|            |... .|.||||  |.|| |. .. .    | . | .
--QMQMMFKKIG---------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 86188.m00109.AA AGC 14-244 18 1.3e-56 143.88 In-house 1-373 (395) Show / Hide
Range on Protein: 14-244
Range on HMM: 1-373/395
Sequence Identity: 18% (69 aa)

IKFENVIGVGGYGVLYKVYSE------QYKIFFAMKKIP-----------EKLFNKLE------------VDCLISID----------NPNVVN-LYKSY
 .|  ||| |..|  | |         . . ..|||..            .   .. |             . |  ..          .|..|. |. |.
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

KSNGF--IYLLLEYCP-----------LDLDRLLHGN----TLSNEELIKYTYQ-------MILGIKACHE-NNVAHGD-IKPSNFLIDKYGRIKVCDFG
...    .|...||.|           ..|   |.|     ... |.   |. .       ..|..   |. ... | | .|| | |.|. | || .|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSSYLNQES---------------------------------------------------RMSNFRG--TLLFIAPEILKQEEFCPVKADIWA--LGITI
|.  ....                                                    | . | |  |  ..|||||     .   .|.|.  ||. .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

YLMATQRYPYEGHTSE----------EVLKQIE------SKKISLK-----HIKN-----EVISNIISKCLQIKPNKR
| | | . |. |.. .          |. ..|.      ..|. .      ...      .   ..|.|.|.  |.||
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKR

Pkinase 86188.m00109.AA Pkinase 14-254 25 1.4e-53 189.09 Pfam 1-293 (293) Show / Hide
Range on Protein: 14-254
Range on HMM: 1-293/293
Sequence Identity: 25% (74 aa)

IKFENVIGVGGYGVLYKVYSEQYKIFFAMKKIPEKLFNK-------L--EVDCLISIDNPNVVNLYKSYKSNGFIYLLLEYCPL-----DLDRLLH---G
.... .|| |..|. || .   . . .|.|.|. .  ..       .  |.  . ... ||.| || .. ... ||. .|||.      || ....   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NTL--SNEELIKYTYQMILGIKACHENNVAHGDIKPSNFLIDKYGRI----KVCDFGLSS---YLNQESRMSNFRGTLLFIAPEILKQEEFCPVKADIWA
...  | .|...| ||.. |.. ||.... | |.||.|.|||. | |    |.|||||.    | |..  |. | ||. ..|||...  .  . |.|.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGITIYLMATQRYPYEGH------TSEEVLKQIESKKISLKHIKN---------------------EVISNIISKCLQIKPNKRATINDLHKI--I
.|...| |.. | |. ||      .  .....| .....    .                      |    .|..||. .|.|| |. .. .   .
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 86188.m00109.AA CAMK 19-249 16 5e-52 165.56 In-house 1-418 (425) Show / Hide
Range on Protein: 19-249
Range on HMM: 1-418/425
Sequence Identity: 16% (67 aa)

VIGVGGYGVLYKVYSEQYK------------IFFAMKKIP-------------------------------EKLFN--KLEVDCLIS-------IDNPNV
..| |..|. ....  . .              .|.| |.                               .|     . |.... .       .| ||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNLYKSYKSNGF-------------------IYLLL---EYCPLD------LDRLL-HGN--------------TLSNEELIKYTYQMILGIKACHENNV
..||  | .. .                   .|. .   |||.        .|..  ||.               .. .|  .|  |.. ... ||..|.
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHGDIKPSNFLIDKY-----------------GRIKVCDFGLSSYLNQ------------------------ESRMSNFRGTLLFIA-PEILKQ------
.| |.|| | |.|.                  . ||..|||.. ....                           |. | ||. ..| ||.|..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------EEFCPVKADIWALGITIYLMATQRYPYEGH-------------TSEEVLKQIESKKISLKHIKNEV------------------------ISN
       .. .. |.|.|..|.  | | . ..|..|              . .| ...| . | .  . .                             .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

IISKCLQIKPNKRATIND
 |.|.||  |.||.|| .
LIRKMLQVDPEKRMTIEQ

Kinase 86188.m00109.AA Ciliate-E2 14-254 18 1.6e-48 164.7 In-house 1-365 (365) Show / Hide
Range on Protein: 14-254
Range on HMM: 1-365/365
Sequence Identity: 18% (70 aa)

IKFENVIGVGGYGVLYKV--YSEQYKI---------------------FFAMKKIPEK-LFNKLEVDCLI-----------------SIDNPNVVNLYKS
.|| ..|| |..|. ||.  ...|...                     ..||| . .. ..... .. ..                 ....||....| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YK--SNGFIYLLLEYCPL-DLDRLL-------------HGNTLSNEELIKYTYQMIL---------------GIKACHENN-VAHGDIKPSNFLIDKYGR
..  ..  ||| .|||   ||  ..               . .. .| .....| .                ... .|..| . | ||||.| |.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKVCDFGLSSYLNQESRMSN--------------------------------FRGTLLFIAPEILK--------QEEFCPVKADIWALGITIYLMATQRY
||..||||| ...... .                                  . ||. . |||||.        ...    |.|||.||...| | . ..
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PYEGHTSEEVLKQIESKKIS---------LKHIKNEVIS------------NIISK----CLQIKPNKRAT-INDL--HKII
|.        ..||. .||.         .. .. . ..            ..|.|    .|| .|.|| | ....  |...
PF--------QQQIKQCKIDFPCPEWQKDTQ-CI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 86188.m00109.AA Ciliate-E2-Unclassified 14-254 20 2.8e-47 162.06 In-house 1-352 (352) Show / Hide
Range on Protein: 14-254
Range on HMM: 1-352/352
Sequence Identity: 20% (72 aa)

IKFENVIGVGGYGVLYKVYSEQYKIFFAMKKIP--------------EKLFNKLEVDCL----------------ISIDNPNVVNLYKSYKSNGFIYLLL
 |.  .|| ||.|. ||.. .. | ..||| .               |......|. ..                .....|..|...   ..   ||. .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYCP-------LDL------------DRLLHGNTLSNEELI-----KYTYQMILGIKACHENN-VAHGDIKPSNFLIDKYG---RIKVCDFGLSSYLN--
|||.       .              ....... .. .. .     .|..| ..|.. .|..| . | ||||.| |.|. |   .||..|||.|....  
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

--------------QESRMSNFRGTLLFI----APEILKQEEFCP---VKADIWALGITIYLMATQRYPYEGHTSEE----------------VLKQIES
              .. .|. | ||. ..    |||.|....       |.|||.||. .| | ...||... ..|.                ....|  
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

KKISLKHIKN----EVIS--------NIISKCLQIKPNKRATINDL--HKII
|.|. .. ..      .|        ....|.|. .|||| |....  | ..
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 86188.m00109.AA ULK 14-254 22 1.5e-46 160.49 In-house 1-329 (329) Show / Hide
Range on Protein: 14-254
Range on HMM: 1-329/329
Sequence Identity: 22% (75 aa)

IKFENVIGVGGYGVLYKVYSEQYK----IFFAMKKIP---EKLFN------------KLEVDCLISID--------NPNVVNLYKSYKSNGF--IYLLLE
.   ...| | .|. || . .. |    . .| |.|.   .. .|            | |.. .  ..        .||.| ||. ...  .  ||. .|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPL-DLDRLLH-----------GNTLSNEELIKYTYQMILGIKACHENNVAHGDIKPSNFLIDKY------------GRIKVCDFGLSSYLNQE----S
||.  ||. ...           ...|| .| |.. .| . | |. |..|. | ||||.| ||..             |..|..|||..  .. .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

RMSNFR------GTLLFIAPEILK----QEEFCPVKADIWALGITIYLMATQRYPYEGHTSEE-VLKQIESK------------KISLKHIK-------N
 |  .       || |. ||.||.    |....  |.||| ||. .| | . ..|...   .. .|..|..             |. |.  |        
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

EVISNIISKCLQIKPNKRATINDL--HKII
. . ..|...||.....| .. .|  |...
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 86188.m00109.AA STE 14-250 19 3e-46 159.95 In-house 1-351 (359) Show / Hide
Range on Protein: 14-250
Range on HMM: 1-351/359
Sequence Identity: 19% (70 aa)

IKFENVIGVGGYGVLYKVYSEQ---------------YKIFFAMKKIP----------------------EKLFNKLEVDCLISID--NPNVVNLYKSYK
 ..  .|| |..|. || .                   . ..|.|...                      |.   . |.. .   .   ||.|. | .| 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SNG-------FIYLLLEYCP-LDLDRLLH-----GNTLS----------NEELIKYTYQMILG-IKACHENNVAHGDIKPSNFLIDKYGRIKVCDFGLSS
 .|        ... .||..   || ...     |..|.           ........| . |  .  |.... | ||||.| |.     .| ||||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

YLNQE-----------------SRMSNFRGTLLFIAPEILKQEEFCPV------KADIWALGITIYLMATQRYPYEGHTSEEVLKQIE------------
 |...                 ..   | ||  . |||...|.. .        |.||| ||.||  ||| ..|.   .  ... .|             
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----SKKISLKH-------------------IKNEVISNIISKCLQIKPNKRATINDL
     .  .|..                      .   . |.||||. ||||.| ..|
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQL

Kinase 86188.m00109.AA ULK 14-254 21 3.5e-43 149.77 In-house 1-324 (324) Show / Hide
Range on Protein: 14-254
Range on HMM: 1-324/324
Sequence Identity: 21% (70 aa)

IKFENVIGVGGYG-VLYKVYSEQY---KIFFAMKKIP-----EKLFN----------KLEVDCLISID---NPN--VVNLYKSYKSN--GFIYLLLEYCP
.   ...| | .| . || . ..    . ..| |.|.     .|  .          | |.  .  ..   .||  .| ||. ...    .||. .|||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

L-DLDRLLH----------GNTLSNEELIKYTYQMILGIKACHENNVAHGDIKPSNFLIDKY------------GRIKVCDFGLSSYLNQESRMSNFR--
  ||. ...          ...|| .| |.. .| . | |. |..|. | ||||.| || .             |..|..|||..  .. ..   . .  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GTLLFIAPEILK----QEEFCPVKADIWALGITIYLMATQRYPYEGHTSEEVLKQ--------------IESKKISLK---HIKN--EVISN
        || |. ||.||.    |....  |.||| ||. .| | . .||...   ..  ..              |. ..|  .    ...  . . .
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

IISKCLQIKPNKRATINDL--HKII
.|...||.....| .. ..  |...
LIRRMLQYDEKDRISWEEIFNHPWF

Kinase 86188.m00109.AA CAMKL 42-250 24 5.4e-41 128.46 In-house 38-291 (297) Show / Hide
Range on Protein: 42-250
Range on HMM: 38-291/297
Sequence Identity: 24% (63 aa)

MKKIPEKLFNKL------------EVDCLISID---NPNVVNLYKSYKSNGF------IYLLLEYCP---LDLDRLL--HGN---TLSNEELIKYTYQMI
....| .. ||.            |. .. ...    ||.. ||  .    .      ||| .|||.   .||   .  ||.    .. .|  .|  |..
IWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIV

LGIKACHENNVAHGDIKPSNFLIDKYG--RIKVCDFGLSSYLN-Q----ESRMSNFRGTLLFIAPEILKQ--EEFCPVKADIWALGITIYLMATQRYPYE
 ... ||.....| |||| | |.|. |   ||..|||.| .   .    .  .. | |.. . ||||..   ....  |.|||..|.. | | . ..| .
SAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFD

GHT---------SEEVLKQIESKKI-SLKHIKNEVISNIISKCLQIKPNKRATINDL
. |          ..  . .  ...   .|.  ... ..|.| || .|.||.|| ..
DDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCR-DLIRKMLQVNPEKRPTIHQI

Kinase 86188.m00109.AA MARK 110-250 34 7.8e-35 111.41 In-house 112-256 (262) Show / Hide
Range on Protein: 110-250
Range on HMM: 112-256/262
Sequence Identity: 34% (51 aa)

QMILGIKACHENNVAHGDIKPSNFLIDKYG--RIKVCDFGLSSYLNQESRMSNFRGTLLFIAPEILKQEEFCPVKADIWALGITIYLMATQRYPYEGHT-
|.. ... ||..|..| |||| | |||. |   || .|||.|   . ... . | ||. . ||||..... .  |.|||.||.  | | . ..|..| | 
QIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQ

-SEEVLKQIESKKIS-LKHIKNEVISNIISKCLQIKPNKRATINDL
  .|  |.| . | .   |.  | . |.|.. |.. |..|.|| ..
DYKELYKKILRGKYDIPCHVSKE-CRNLIQRLLTVNPEERPTIEEI

Kinase 86188.m00109.AA TKL 20-254 15 1.5e-33 117.81 In-house 1-364 (364) Show / Hide
Range on Protein: 20-254
Range on HMM: 1-364/364
Sequence Identity: 15% (56 aa)

IGVGGYGVLYKV-YSEQY-------KIFFAMKKIPEK--------------------------------LFNKLEVDCLISIDNPNVVNLYKSYKSNGF-
|| ||.|. ||  .  .            |.||....                                 | . |. ...... ||.| .. . ..... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------IYLLLEYCPL-D-LDRLLHGNTLSNEELIKYTYQMILGIKACHENN--------VAHGDIKPSNFLIDKYGR--------------IK
            ...  ||||  . |..|.       . ...  ... .|.   | .|        ..| |.|..| |.|. ..              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

VCDFGLSSYLNQES--------------------RMSNFRGTLLFIAPEILKQEEF---------------CPVKADIWALGITIYLMATQRYPYEGHTS
.||||||  ..|..                    . .. .||. . |||.|.....                  |.|... || .. ..| . ||... .
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

EE-----------VLKQIESKKISLK------------HIKNEVISNIISKCLQIKPNKRATINDLHKII
..           ..   ....  ..            .   . ..... .| . .|.|| . ... |..
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase 86188.m00109.AA TyrKc 14-254 19 5.1e-14 4.0 SMART 1-280 (280) Show / Hide
Range on Protein: 14-254
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

IKFENVIGVGGYGVLYK-VYSEQYKIFFAMKKIP---EKLFNKLEVDCLISI--DNPNVVNLYKSYKSN-------GFIYLLLEYCPL-DLDRLLHGNT-
|... ..| | .|. || ...    |  | |..    .. |   |   . ..  ..||.|.||    .        . .....||.|. ||.  |. .  
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDAREDF-MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-LSNEELIKYTYQMILGIKACHENNVAHGDIKPSNFLIDKYGRIKVCDFGLSSYLNQE-------SRMS-----NFR--GTLLFIAPEILKQEEFCPVKA
 |....|... .|   |    |..|. | |.   | |... ...|..||||| ..  .       .  .     . .    .   ||| . ..  .  | 
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKS

DIWALGITIYLMATQ-RYPYEG-----HTSEEVLKQIESK-KISLKHI--------KNEVISNIISKCLQIKPNKRATINDLHKII
|.|. |.... . |    ||.|      . .||......       .           . . .|...| . .|..| | ...|...
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 86188.m00109.AA Pkinase_Tyr 134-254 21 0.001103 13.1 Pfam 143-270 (270) Show / Hide
Range on Protein: 134-254
Range on HMM: 143-270/270
Sequence Identity: 21% (29 aa)

LIDKYGRIKVCDFGLSSYL--------NQESRMSNFRGTLLFIAPEILKQEEFCPVKADIWALGITIYLMAT-QRYP-YEGHTSEEVLKQI-ESKKISLK
|... . .|.|||||. ..         ... .   . .    ||| ..  . . .| |.|. |.... . |  . | |.| . |||...| |.    ..
LVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM----APECINYGK-FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR-MP

HIK--NEVISNIISKCLQIKPNKRATINDLHKII
  .   . | ... .| . .|..| |  ..| ..
CPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase 86188.m00109.AA Pkinase_Tyr 54-110 25 0.155631 5.82 Pfam 53-119 (270) Show / Hide
Range on Protein: 54-110
Range on HMM: 53-119/270
Sequence Identity: 25% (17 aa)

EVDCLISI-DNPNVVNLYKSYK-SNGF--IYLLLEYCPL-DLDRLLHGN-----TLSNEELIKYTYQ
|.  . .. ..||.|.||       .   ||. .||.|. ||.  |. .      |. ..|... .|
EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQ