Gene 94222.m00136 (T.vaginalis)

94222.m00136

Species: T.vaginalis
Alias: TvagK0240, 94222.m00136
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
94222.m00136.AA Protein None 129 None Fasta, JSON
94222.m00136.kin_dom Protein Kinase Domain None 126 None Fasta, JSON

Protein domain

Protein domains of 94222.m00136.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94222.m00136.AA CAMK 4-129 17 1.3e-23 72.37 In-house 95-317 (425) Show / Hide 
Range on Protein: 4-129
Range on HMM: 95-317/425
Sequence Identity: 17% (40 aa)

IKNSNIVNLYKYVH------------QGPY--------VYLMM---ELCRSN-----LEEFLKENKD---------------VPSSKLHDIAFGMINAVN
..  ||..|| .                 .        .|. |   |.|        | ....|...               .. .  . .   .. ||.
LDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVH

CCHANGISHGDIKPSNFLFDFN-----------------GRIKICDFGLAQKSLH------------------------EQIYTNLSGTMMFLA-PEVIQ
 || ..| | |.|| | |.| |                 . |||.|||.|.|  .                         | ..   ||  . | |||..
YCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLN

R-------------LPFDAFAADI
.              | . ...|.
GKGHCNMQNATDEEKPYYGPKCDM
Kinase 94222.m00136.AA Pkinase 8-123 30 9.6e-23 81.5 Pfam 61-190 (293) Show / Hide 
Range on Protein: 8-123
Range on HMM: 61-190/293
Sequence Identity: 30% (40 aa)

NIVNLYKYVHQGPYVYLMMELCRS-----NLEEFLK--ENKDV--PSSKLHDIAFGMINAVNCCHANGISHGDIKPSNFLFDFNGRI----KICDFGLAQ
||| || ... ....|. ||.|.       | ....  ... .  .   . ...  .. ... ||..|| | |.||.|.|.| || |    |||||||| 
NIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAK

K--SLHEQIYTNLSGTMMFLAPEVIQ-RLPFD
.    . . .| . ||  ..|||||. . . .
QFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYG
Kinase 94222.m00136.AA Ciliate-E2 4-129 20 1.1e-22 74.64 In-house 89-279 (365) Show / Hide 
Range on Protein: 4-129
Range on HMM: 89-279/365
Sequence Identity: 20% (40 aa)

IKNSNIVNLYKYVH--QGPYVYLMMELCRS-NLEEFLKENKDVPSSKLH-----------DIAFGMIN---------------AVNCCHANG-ISHGDIK
... ||...| .    .  ..|| ||.|   .|....|.||    ....           .|    ..               |.. .| .. | | |||
LNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIK

PSNFLFDFNGRIKICDFGLAQKSLHE--------------------------------QIYTNLSGTMMFLAPEVIQRLPFDA--------FAADI
|.| ||     |||.||||..|   .                                ... .. || ...|||.... . |         ...||
PENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDI
Kinase 94222.m00136.AA CAMKL 8-129 30 2.5e-22 67.91 In-house 76-219 (297) Show / Hide 
Range on Protein: 8-129
Range on HMM: 76-219/297
Sequence Identity: 30% (44 aa)

NIVNLYKYVHQGPY------VYLMMELCRSN---LEEFLKENKD----VPSSKLHDIAFGMINAVNCCHANGISHGDIKPSNFLFDFNG--RIKICDFGL
||. ||  .    .      .|| ||.| .    | ........     | .  . .   .. ||| || .|| | |||| | |.| ||   |||.|||.
NIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGF

AQKSL-H----EQIYTNLSGTMMFLAPEVIQR--LPFDAFAADI
. .   .    .|  .   |.  . |||..|.   |.|....||
SNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDI
Kinase 94222.m00136.AA Ciliate-E2-Unclassified 1-129 22 4.7e-22 73.29 In-house 75-253 (352) Show / Hide 
Range on Protein: 1-129
Range on HMM: 75-253/352
Sequence Identity: 22% (40 aa)

MIAIKNSNIVNLYKYVHQGPYVYLMMELCRS-NLEEFLKENKD-----------------VPSSKLH-----DIAFGMINAVNCCHANG-ISHGDIKPSN
.. ... .||... .  .  ..|. ||.|.  .|....|..|                  ..  .       ...   ... . .| .. | | ||||.|
LLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPEN

FLFDFNG---RIKICDFGLAQKSL----------------HEQIYTNLSGTMMFL----APEVIQRLPFDA---FAADI
 ||| ||   .|||.|||.. |.                  .|...  .|| ...    ||||.|.   |    ...||
ILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDI
Kinase 94222.m00136.AA CDC2 8-93 35 3.1e-21 61.55 In-house 62-150 (301) Show / Hide 
Range on Protein: 8-93
Range on HMM: 62-150/301
Sequence Identity: 35% (32 aa)

NIVNLYKYVHQGPYVYLMMELCRSNLEEFLK----ENKDVPSSKLHDIAFGMINAVNCCHANGISHGDIKPSNFLFDFNGRIKICDFGLA
||| |   .||   .|.  | .  .| ....     || .|.... .... ....|. ||...| | |.||.| | | .|.||| |||||
NIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLA
Kinase 94222.m00136.AA ULK 5-129 24 6.6e-19 62.7 In-house 76-239 (329) Show / Hide 
Range on Protein: 5-129
Range on HMM: 76-239/329
Sequence Identity: 24% (40 aa)

KNSNIVNLYKYVHQG--PYVYLMMELCRS-NLEEFLKENKD----------VPSSKLHDIAFGMINAVNCCHANGISHGDIKPSNFLFDFN---------
.. ||| ||..       ..|..||.|   .||...|.||            . ..   .    .|.  . | ..| | ||||.| | . .         
HHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV

---GRIKICDFGLAQKSLHE----QIYTNLS------GTMMFLAPEVIQRL----PFDAFAADI
   |..||.|||.|..   .    |...  .      || .. ||...|..    |.. . .||
HPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDI
Kinase 94222.m00136.AA CMGC 8-117 20 6.9e-19 57.85 In-house 99-297 (513) Show / Hide 
Range on Protein: 8-117
Range on HMM: 99-297/513
Sequence Identity: 20% (40 aa)

NIVNLYKYVHQGP-----------------YVYLMMELCRSNLEEFLKENKD-------VPSSKLHD--------------IA------FGMINAVN--C
|||.|| ...                    ..|| .|..  .| ...|.|..       .| |  |.              .       . ......   
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKY

CHANG--ISHGDIKPSNFLFDFN--------------------GRIKICDFGLAQKSLHE----------------------QIYTNLSGTMMFLAPEVI
|| ..  | | |.||.| |.. |                    ||.|||||||| .  ..                      . ||.   |.   |||..
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL
Kinase 94222.m00136.AA MARK 55-129 41 1.9e-18 57.08 In-house 113-189 (262) Show / Hide 
Range on Protein: 55-129
Range on HMM: 113-189/262
Sequence Identity: 41% (32 aa)

MINAVNCCHANGISHGDIKPSNFLFDFNG--RIKICDFGLAQKSLHEQIYTNLSGTMMFLAPEVIQRLPFDAFAADI
.. ||| || ..| | |||| | | | ||   |||.|||.. .   .|  .   ||  . |||.... | |....||
IVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDI
Kinase 94222.m00136.AA ULK 4-129 24 5.7e-17 56.79 In-house 70-235 (324) Show / Hide 
Range on Protein: 4-129
Range on HMM: 70-235/324
Sequence Identity: 24% (41 aa)

IKNSN--IVNLYKYVHQG--PYVYLMMELCRS-NLEEFLKENKD---------VPSSKLHDIAFGMINAVNCCHANGISHGDIKPSNFLFDFN-------
.|. |  || ||..       ..|..||.|   .||...|.||           . ..   .    .|.  . | ..| | ||||.| |   .       
LKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSK

-----GRIKICDFGLAQKSLHE----QIYTNLS------GTMMFLAPEVIQRL----PFDAFAADI
     |..||.|||.|..   .    |... .       || .. ||...|..    |.. . .||
KVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDI
Kinase 94222.m00136.AA TKL 1-118 20 6.7e-17 57.39 In-house 79-246 (364) Show / Hide 
Range on Protein: 1-118
Range on HMM: 79-246/364
Sequence Identity: 20% (36 aa)

MIAIKNSNIVNLYKYVHQGPY-------------VYLMMELC-RSNLEEFLKENKDVPSSKLHDIAFGMINAVNCCHANG--------ISHGDIKPSNFL
|. ..  ||| .. |. ..|.              .. ||.| . .|...|        ......| ..  ..|  |...        | | |.|..| |
MSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNIL

FDFNGR--------------IKICDFGLAQ-KSLHEQ-------------------IYTNLSGTMMFLAPEVIQ
 | |..              .|||||||.. .| ...                      .  ||  ..||||..
VDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLR
Kinase 94222.m00136.AA S_TKc 1-126 17 1.2e-07 -64.98 SMART 16-231 (231) Show / Hide 
Range on Protein: 1-126
Range on HMM: 16-231/231
Sequence Identity: 17% (40 aa)

MIAIKNS--------------------------NIVNLYKYVHQGPYVYLMMELCRS---NLEEFLKENKD------VPSSKLHDIAFGMINAVNCCHAN
. .....                          |||.|| . .   ..|. ||.|     .| ...|...        |      ..  ...|.. || .
YKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH

GISHGDIKPSNFLFDFNGRIKICDFGLAQKSLHEQIYTNLSGTMMFLAPEVIQRLPF-------------------------------------------
|| | |.||.| |.|   .||||||||| .       | . ||  ..||||.    .                                           
GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIGSPEAKDFIRK

-----------------------DAFA
                       . . 
CLQKDPEKRPTAEALQDEWDIKCHPWF