Gene 93204.m00236 (T.vaginalis)

93204.m00236

Species: T.vaginalis
Alias: 93204.m00236, TvagK0222
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
93204.m00236.AA Protein None 321 None Fasta, JSON
93204.m00236.kin_dom Protein Kinase Domain None 244 None Fasta, JSON

Protein domain

Protein domains of 93204.m00236.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93204.m00236.AA Ciliate-E2 66-257 20 9.6e-20 64.43 In-house 94-365 (365) Show / Hide 
Range on Protein: 66-257
Range on HMM: 94-365/365
Sequence Identity: 20% (59 aa)

IVTVHEFIR--FNQFVFIVMEYCRY-DIEKFIRNG--------------LKVETTDLSRYIKL------------TIEAVISCHIFS-IFGLNIKPSNFL
|.  .|.     .. ...||||| . | ...|.|                  |  .....|               |.|. ..|    |.  .|||.| |
IIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENIL

IDQFGRLKISDFYY------LPEIRTHYNSQT---------------------------ITQINRYSAPEILHRIEMGN--------EKSDVWSLGATIY
.     .||.|| .        . ||| ..|                            |     | ||||| . . .|        .|.|.|||| ..|
F-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILY

YMATGKSPFNNQDSLELINTINRADYD----------------KDQIFDPFLKEVISY----CLQPNPLNRKM-LSELLNCDYF
.| .|| ||      . ..  .  |..                . .  ..  |  |.     .|| .| .|    ...||  .|
EMLFGKPPF------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 93204.m00236.AA Ciliate-E2-Unclassified 14-257 17 1.3e-18 61.16 In-house 1-352 (352) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-352/352
Sequence Identity: 17% (63 aa)

IQVLSLISNNGYSQIFTASSDRYPNGI-----ALKRIIAT-----KVNFDVLQRLNTMDDSK--------------------IVTVHEFIRF--NQFVFI
  ..  | . |..... .  .     .     . | .|       ... . .. ...|   |                    .. |..|  |   | ..|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEYCRY-DIEKFIRNGLK-----------------VETTDLS-----RYIKLTIEAVISCHIFS-IFGLNIKPSNFLIDQFG---RLKISD-----FYY
|||||.. | ...|..  |                 ..    .     .|..  ...  ..|    |   .|||.| |.|. |   ..||.|     .| 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

LPEIRTHYN------------SQTITQINRYS----APEILHRIEMGN---EKSDVWSLGATIYYMATGKSPFNNQDSLE----------------LINT
 ..  . .|            ..|... ..|     |||.| . . ..   .|.|.||||  .|.| .|. ||. ... .                |.. 
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

INRADYDKD--------QIFDPFLKEVIS----YCLQPNPLNRKMLSELLNCDYF
|.  .....        .. .|  |. |.     .|. || .|  ....||  .|
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 93204.m00236.AA PLK1 65-257 25 2.3e-17 53.4 In-house 60-253 (253) Show / Hide 
Range on Protein: 65-257
Range on HMM: 60-253/253
Sequence Identity: 25% (50 aa)

KIVTVHEFIRFNQFVFIVMEYCRYDIEKFIRNGLKVETTDLSRY-IKLTIEAVISCHIFSIFGLNIKPSNFLIDQFGRLKISDFYYLPEIRTH-YNSQTI
.|| .|.|   .|.|.||.| ||      .    |  |   .|| ..  .|..   |   |    .|  |  ...  ..|| ||    ..  .    .|.
HIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPECRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTL

TQINRYSAPEILHRIEMGNEKSDVWSLGATIYYMATGKSPFNNQDSLELINTINRADYDKDQIFDPFLKEVISYCLQPNPLNRKMLSELLNCDYF
     | |||.| ..    |  |.||.|  .| .  |. ||  .   |    | ...|   ..  .  ...|   |.|.| .|   ...|| ..|
CGTPNYIAPEVLNKKGHSFE-VDIWSIGCIMYILLFGQPPFETKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase 93204.m00236.AA Pkinase 167-257 22 5.4e-16 57.63 Pfam 176-293 (293) Show / Hide 
Range on Protein: 167-257
Range on HMM: 176-293/293
Sequence Identity: 22% (26 aa)

RYSAPEILHRIEMGNEKSDVWSLGATIYYMATGKSPFNNQ------DSLELINTINRADYDKDQIFD---------------------PFLKEVISYCLQ
.| |||..   ..   |.|.||.| ..|.|..|. || ..      | ...|. | ..... |   .                     . .|..|..||.
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC

PNPLNRKMLSELLNCDYF
..|  |    ..|. ..|
KDPKKRPTAEQILQHPWF
Kinase 93204.m00236.AA S_TKc 14-257 22 6.5e-16 56.41 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-231/231
Sequence Identity: 22% (59 aa)

IQVLSLISNNGYSQIFTASSDRYPNGIALKRIIATKVNFDVLQRLNTMDDSKIVTVHEFIRFNQFVFIVMEYCRY---DIEKFIRNGLK------VETTD
 ..| .|   .... . .   .     |.|.|   .     .| |   .   ||. .....  .....|||||     |  ..|..  .          .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

LSRYIKLTIEAVISCHIFSIFGLNIKPSNFLIDQFGRLKISDF----YYLPEIRTHYNSQTITQINRYSAPEILHRIEMGNEKSDVWSLGATIYYMATGK
  .|.. ...|.  ||   |    .||.| |.|.  ..||.||     .           |.     | |||.|     | .|.|.||.| ..| |..|.
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

SPFNNQDSLELINTINRADYDKDQIFDPFLKEVISYCLQPNPLNRKMLSELLN-------CDYF
 ||   .  .... |           .| .|. |. ||| .| .|    |.|.         .|
PPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 93204.m00236.AA CAMK 168-257 21 4.8e-15 44.21 In-house 285-425 (425) Show / Hide 
Range on Protein: 168-257
Range on HMM: 285-425/425
Sequence Identity: 21% (30 aa)

YSA-PEILHR-------------IEMGNEKSDVWSLGATIYYMATGKSPFNNQ-------------DSLELINTINRADYD-KDQIFDP-----------
| | ||.| .             ..  ..|.|.||.|   | | .|..||.               .  ||   | ...||  .  |.|           
YMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWD

------------FLKEVISYCLQPNPLNRKMLSELLNCDYF
              |  |. .||..| .|  ... ||   .
DISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 93204.m00236.AA Ciliate-E1 20-187 19 5.5e-15 45.6 In-house 1-202 (202) Show / Hide 
Range on Protein: 20-187
Range on HMM: 1-202/202
Sequence Identity: 19% (39 aa)

ISNNGYSQIFTASSDRYPNGIALKRIIATKVNFD------VLQRLN-TMDDSK----IVTVHEFIR--FNQFVFIVMEYCRYDIEKFIR-----------
|.|...|..| | .. . .    . || .. |..      ...  .  |.  |    |. . ..|.  .|..  |..|.| .  .. ..           
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

--NGLKVETTDLSRYIKLTIEAVISCHIFSIFGLNIKPSNFLIDQFGRLKISDFYYLP--EIRTHYNSQTITQINRYSAPEIL-------HRIEMGNEKS
  |  .   . . . |.  |...|  |.. |  ..|||.| ||...|.....||.        . ...|   ... |. || .        . .  | ||
QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKS

DVW
|. 
DIY
Kinase 93204.m00236.AA ULK 168-257 25 8.1e-15 48.23 In-house 217-329 (329) Show / Hide 
Range on Protein: 168-257
Range on HMM: 217-329/329
Sequence Identity: 25% (29 aa)

YSAPEILH----RIEMGNEKSDVWSLGATIYYMATGKSPFNNQDSLELINTINRADYD--------------------KDQIFDPFLKEVISYCLQPNPL
| ||.||.    ... .. |.|.||||  .|.| .|| ||...   .... |..  ..                    .|... | .|. |. .|| .. 
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEK

NRKMLSELLNCDYF
 |    ||.|   |
DRISWEELFNHPWF
Kinase 93204.m00236.AA MELK 55-257 22 2.5e-14 45.05 In-house 48-254 (254) Show / Hide 
Range on Protein: 55-257
Range on HMM: 48-254/254
Sequence Identity: 22% (47 aa)

LQRLNTMDDSKIVTVHEFIRFNQFVFIVMEYCR-YDIEKFIRNGLKVETTDLSRYIKLTIEAVISCHIFSIFGLNIKPSNFLIDQFGRLKISDFYYLPEI
.. |  .   .|  .. .|  .. .|.|||||   ..  .|    ..|  .   . .  . |.   |       ..|| |.|.|.  .||. ||      
MDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKT

RTHYNSQ---TITQINRYSAPEILHRIEMGNEKSDVWSLGATIYYMATGKSPFNNQDSLELINTINRADYDKDQIFDPFLKEVISYCLQPNPLNRKMLSE
. . .     |      | |||..   .   .  ||||.|  .| .  |  ||.      .   | .  |.. .   |  |...   || .|  |  . .
KGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKN

LLNCDYF
||| .. 
LLNHPWV
Kinase 93204.m00236.AA ULK 168-257 24 3e-14 47.03 In-house 213-324 (324) Show / Hide 
Range on Protein: 168-257
Range on HMM: 213-324/324
Sequence Identity: 24% (28 aa)

YSAPEILH----RIEMGNEKSDVWSLGATIYYMATGKSPFNNQDSLELI----------------NTINRADYD---KDQIFDPFLKEVISYCLQPNPLN
| ||.||.    ... .. |.|.||||  .|.| .|| ||...   ...                   .  ...   ||... | .|. |. .|| ..  
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKD

RKMLSELLNCDYF
|    |..|   |
RISWEEIFNHPWF
Kinase 93204.m00236.AA AGC 168-257 23 8.3e-14 30.59 In-house 273-395 (395) Show / Hide 
Range on Protein: 168-257
Range on HMM: 273-395/395
Sequence Identity: 23% (30 aa)

YSAPEILHRIEMGNEKSDVWS--LGATIYYMATGKSPFNNQDSL----------ELINTINRAD---YDKDQI-------------FDPFLKEVISYCLQ
| |||||      .   | ||  ||. .| | ||..||....            |. . |   .    .| ..             |.| .|  |. .|.
YMAPEIL-----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLC

PNPLNRKM----------LSELLNCDYF
..| .|             .|. |  .|
KDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 93204.m00236.AA CAMKK 185-257 21 2.3e-09 25.41 In-house 308-396 (396) Show / Hide 
Range on Protein: 185-257
Range on HMM: 308-396/396
Sequence Identity: 21% (19 aa)

DVWSLGATIYYMATGKSPFNNQDSLELIN---TI--NRADYDK-----------DQIFDPFLKEVISYCLQPNPLNRKMLSELLNCDYF
|.|.||.|.|.. .|| ||.... ..| .    |  .   . .           .    . || .|  .|. ||  | ....... . .
DIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPWV
Kinase 93204.m00236.AA CAMKK 129-147 54 1e-06 16.82 In-house 222-243 (396) Show / Hide 
Range on Protein: 129-147
Range on HMM: 222-243/396
Sequence Identity: 54% (12 aa)

IKPSNFLIDQFG---RLKISDF
|||.| |||. |   ..||.||
IKPQNILIDEEGCGEHVKIADF
Kinase 93204.m00236.AA AGC 129-147 47 3e-06 10.49 In-house 181-199 (395) Show / Hide 
Range on Protein: 129-147
Range on HMM: 181-199/395
Sequence Identity: 47% (9 aa)

IKPSNFLIDQFGRLKISDF
.|| | |.|. | .|..||
LKPENILLDEDGHIKLTDF
Kinase 93204.m00236.AA Pkinase 66-147 25 5e-06 22.31 Pfam 62-156 (293) Show / Hide 
Range on Protein: 66-147
Range on HMM: 62-156/293
Sequence Identity: 25% (24 aa)

IVTVHEFIRFNQFVFIVMEYCRY-----DIEKFIR--NGLKV--ETTDLSRYIKLTIEAVISCHIFSIFGLNIKPSNFLIDQFGRL----KISDF
||. ... . .. . .|||||.      |   .|.  .. ..  .  .. .|.. .....  ||  .|    .||.|.|||. | .    ||.||
IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDF
Kinase 93204.m00236.AA TyrKc 14-252 15 2.5e-05 -136.46 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-252
Range on HMM: 1-280/280
Sequence Identity: 15% (46 aa)

IQVLSLISNNGYSQIFTASSDRYPNGIALKRIIATKVNFDVLQRLNTM-----DDSKIVTVHEFIRFN-------QFVFIVMEYCRY-DIEKFIRNGLKV
|. .  . .  . ... .  .      | | . . .   | .. .. |     .   ||  .  ..         . ..|||||. . |  ...|.  . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

ETTDLSRYIKLTIEAVISCHIFSIFGLNI-----------------KPSNFLIDQFGRLKISDF------YYL-------PEIRTHYNSQTIT-QINRYS
                ..   .  | . |                    | |..  .. |||||      |           .|.   ... |    |  
----------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM

APEILHRIEMGNEKSDVWSLGATIYYMAT-GKSPFNN-----QDSLELINTINRADY-DKDQI--------FDPFLKEVISYCLQPNPLNR---KMLSEL
||| . .  . ..|||||| | ... . | |..|  .      .  |.|. . . .. .. .           . . .... | . .| .|   . . |.
APECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHEC

L
.
F
Kinase 93204.m00236.AA CAMK 53-147 16 0.000583 7.86 In-house 83-240 (425) Show / Hide 
Range on Protein: 53-147
Range on HMM: 83-240/425
Sequence Identity: 16% (26 aa)

DVLQRLNT----MDDSKIVTVHEFIRF-------------------NQFVFIVM---EYCRYD------IEKFIRNGL--------------KVETTDLS
.....|.     .|   |.  .|..                     ......||   |||          .. ...|               ...  . .
EIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREAR

RYIKLTIEAVISCHIFSIFGLNIKPSNFLIDQF-----------------GRLKISDF
||..  ..||  ||   |  . .|| | |.|.                  . .||.||
RYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF
Kinase 93204.m00236.AA ULK 66-94 31 0.039917 3.32 In-house 80-111 (329) Show / Hide 
Range on Protein: 66-94
Range on HMM: 80-111/329
Sequence Identity: 31% (10 aa)

IVTVHEFIRFNQF--VFIVMEYCRY-DIEKFI
||  ... .  ..  ..|.||||   | |..|
IVKLYDWFETSNHNNIYIIMEYCNGGDLEQYI
Kinase 93204.m00236.AA ULK 66-94 31 0.042609 3.31 In-house 77-108 (324) Show / Hide 
Range on Protein: 66-94
Range on HMM: 77-108/324
Sequence Identity: 31% (10 aa)

IVTVHEFIRFN--QFVFIVMEYCRY-DIEKFI
||  ... .     ...|.||||   | |..|
IVKLYDWFETSNHNNIYIIMEYCNGGDLEQYI
Kinase 93204.m00236.AA ULK 129-147 38 0.282908 0.31 In-house 156-186 (329) Show / Hide 
Range on Protein: 129-147
Range on HMM: 156-186/329
Sequence Identity: 38% (12 aa)

IKPSNFLIDQF------------GRLKISDF
|||.| ||.              |.|||.||
IKPQNILIHNGQPKTDSKKVHPNGVLKIADF