Gene 91881.m00047 (T.vaginalis)
91881.m00047
Species: T.vaginalis
Alias: 91881.m00047, TvagK1018
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 91881.m00047.AA | Protein | None | 132 | None | Fasta, JSON |
| 91881.m00047.kin_dom | Protein Kinase Domain | None | 98 | None | Fasta, JSON |
Protein domains of 91881.m00047.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 91881.m00047.AA | CAMK | 19-99 | 15 | 1e-12 | 36.55 | In-house | 1-160 (425) | Show / Hide |
Range on Protein: 19-99 Range on HMM: 1-160/425 Sequence Identity: 15% (25 aa) VIAKGGFGTIYSVYHVNYK------------STFALKFIP---------------------------------MIAFSQSELDCLIA-------LDDPKI .. .|.||. . ..| | . .| |.|. . .. ..|.... || | | TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI IRLYKYFTY-------------------KDNCYMLM---ELCTN-----DLEKYIKMKKN |.|| .. ....|| | |.|.. || ||. ... IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGC |
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| Kinase | 91881.m00047.AA | CMGC | 14-98 | 14 | 1.1e-11 | 33.74 | In-house | 1-149 (513) | Show / Hide |
Range on Protein: 14-98
Range on HMM: 1-149/513
Sequence Identity: 14% (22 aa)
IVFNNVIAKGGFGTIYSVYH--------------VNYKSTFALKFIP---MIAFSQ-------------SELDCLIAL-----------------DDPKI
..| .| .|. |. .. ... |.| | . . |. .| | ... |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI
IRLYKYFTYKD-----------------NCYMLMELCTNDLEKYIKMKK
..|| .|..|. . |. .|.. .|| .|||...
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQ
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| Kinase | 91881.m00047.AA | Ciliate-E2 | 14-110 | 16 | 1.3e-11 | 36.12 | In-house | 1-152 (365) | Show / Hide |
Range on Protein: 14-110 Range on HMM: 1-152/365 Sequence Identity: 16% (25 aa) IVFNNVIAKGGFGTIYSV--YHVNYKS----------------TFALKFIPMIAFSQSELDCLIALDDPK-----------------------IIRLYKY . |...| .|.||..| . . |.... .. |.. | ...... . .. ||..| . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FT--YKDNCYMLMELCTN-DLEKYIK------------MKKNIDKFEMRKLIQ | ..|.|. ||.| ||..||| |... .|...... FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMK |
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| Kinase | 91881.m00047.AA | ULK | 14-111 | 23 | 4.5e-10 | 32.0 | In-house | 1-134 (324) | Show / Hide |
Range on Protein: 14-111 Range on HMM: 1-134/324 Sequence Identity: 23% (31 aa) IVFNNVIAKGGFG-TIYSVYHVNY---KSTFALKFIP---MIAFSQ------------SELDCLIALD---DPK--IIRLYKYFTYK--DNCYMLMELCT .. |... || || . | .... . .| | |. |. ... .| . |. | |..||..| . .|.|. ||.| YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN N-DLEKYIK---------MKKNIDKFEMRKLIQD |||.||| ||.. | .. ... GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQ |
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| Kinase | 91881.m00047.AA | ULK | 14-111 | 23 | 2.4e-09 | 28.85 | In-house | 1-138 (329) | Show / Hide |
Range on Protein: 14-111 Range on HMM: 1-138/329 Sequence Identity: 23% (32 aa) IVFNNVIAKGGFGTIYSVYHVNYK----STFALKFIP---MIAFS------------QSELDCLIALDDPK--------IIRLYKYFTYK--DNCYMLME .. |... || ||. | .... | .| | |. |. .. ..| . . |..| |..||..| . .|.|. || YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME LCTN-DLEKYIK----------MKKNIDKFEMRKLIQD .| |||.||| ||.. | .. ... YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQ |
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| Kinase | 91881.m00047.AA | Ciliate-E2-Unclassified | 14-109 | 17 | 1.7e-07 | 22.11 | In-house | 1-149 (352) | Show / Hide |
Range on Protein: 14-109 Range on HMM: 1-149/352 Sequence Identity: 17% (26 aa) IVFNNVIAKGGFGTIYSVYHVNYKSTFALKFIP---MIA-----------FSQSELDCL----------------IALDDPKIIRLYKYFTYKDNCYMLM .. .| .||||..| ..| . | .|.| . ... ... |. .. . ...| |.... .|. |.|.|. | YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM ELCTN-DLEKYIKMKKN-----------------IDKFEMR-----KLI |.| . ||..||| .|. .. .... ... EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYF |
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| Kinase | 91881.m00047.AA | CK1 | 14-106 | 18 | 5.6e-07 | 20.46 | In-house | 1-132 (339) | Show / Hide |
Range on Protein: 14-106
Range on HMM: 1-132/339
Sequence Identity: 18% (24 aa)
IVFNNVIAKGGFG-TIYSV-----YHVNYK-----STFALKFIPMIAF---SQSELDCLIALD-----------------------DPKIIRLYKYFTYK
|..|||| .|| | . .. . .|.| | . .| . . .. . | ..... .. .
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED
DNC-YMLMELCTNDLEKYIKMKKNID-KFEMR
|.. || |.|. .||.. |.... . || |.
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMK
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| Kinase | 91881.m00047.AA | AGC | 14-104 | 17 | 7.2e-07 | 12.24 | In-house | 1-144 (395) | Show / Hide |
Range on Protein: 14-104 Range on HMM: 1-144/395 Sequence Identity: 17% (25 aa) IVFNNVIAKGGFGTIYSVYHV------NYKSTFALKFIP-----------MIAFSQSE------------LDCLIALD----------DPKIIR-LYKYF | || ||.||. | | .. . .|.| . |.. ..| . | .. | |.. |. | FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF TYKDN--CYMLMELCT---------NDLEKYIKMKK--NIDKFE ||. |..||.. ..| .. ... . .|. QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFD |
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| Kinase | 91881.m00047.AA | Pkinase | 64-109 | 32 | 6e-06 | 22.11 | Pfam | 60-114 (293) | Show / Hide |
Range on Protein: 64-109 Range on HMM: 60-114/293 Sequence Identity: 32% (18 aa) PKIIRLYKYFTYKDNCYMLMELCTN-----DLEKYIK--MKKNI--DKFEMRKLI | |.||| .|..||..|| ||.| . || ||. ..... . | .. . PNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYM |
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| Kinase | 91881.m00047.AA | SAK | 16-97 | 25 | 9e-06 | 15.41 | In-house | 3-93 (254) | Show / Hide |
Range on Protein: 16-97 Range on HMM: 3-93/254 Sequence Identity: 25% (23 aa) FNNVIAKGGFGTIYSVYHVNYKSTFALKFIP--------MIAFSQSELDCLIALDDPKIIRLYKYFTYKDNCYMLMELCTN-DLEKYIKMK ... |||| ..| . |.| | |. . | . | | |. ||.|| |. .|.| | ....|.| . VQHLLGKGGFACVYRAKCIHTHQEVAIKMIDKKLMQKTGMVQRVRNEVEIHCQLKHPSILELYNYFEDNNYVYLVLEMCHNGEMHRYMKHR |
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| Kinase | 91881.m00047.AA | NAK | 14-43 | 25 | 1.7e-05 | 14.22 | In-house | 1-39 (299) | Show / Hide |
Range on Protein: 14-43 Range on HMM: 1-39/299 Sequence Identity: 25% (10 aa) IVFNNVIAKGGFGTIYSVYH--------VNYK-STFALK . .....|.|||...| |. .|.. .||| YTVEKYLAEGGFSYVYLVQDNYINHPDNPNSNGEKYALK |
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| Kinase | 91881.m00047.AA | S_TKc | 14-132 | 15 | 7.2e-05 | -105.52 | SMART | 1-220 (231) | Show / Hide |
Range on Protein: 14-132
Range on HMM: 1-220/231
Sequence Identity: 15% (36 aa)
IVFNNVIAKGGFGTIYSVYHVNYKSTFALKFIPMIAFSQSELDCLIALDDPKIIRLYKYFTYKDNCYMLMELCTN---DLEKYIKMKKN-----------
. ..| ||.||. | ..|.. . .|.| |. ..|...| . | |..|| .| |. || ||.| . || .||| ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHA
--------------------------------------------------------------IDK-------------------------FEMRKLIQDH
.| ..| |.|
RFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG--
SNSKSSISAK-----------RQRFGFQISK
| .|| ..| . .. .
-----SPEAKDFIRKCLQKDPEKRPTAEALQ
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| Kinase | 91881.m00047.AA | Pkinase | 14-46 | 27 | 0.004524 | 11.94 | Pfam | 1-33 (293) | Show / Hide |
Range on Protein: 14-46 Range on HMM: 1-33/293 Sequence Identity: 27% (9 aa) IVFNNVIAKGGFGTIYSVYHVNYKSTFALKFIP ... .| .|.||. | .|... ..|.| |. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIK |
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