Gene 92747.m00196 (T.vaginalis)

92747.m00196

Species: T.vaginalis
Alias: 92747.m00196, TvagK0556
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
92747.m00196.AA Protein None 241 None Fasta, JSON
92747.m00196.kin_dom Protein Kinase Domain None 173 None Fasta, JSON

Protein domain

Protein domains of 92747.m00196.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 92747.m00196.AA Pkinase 2-123 42 4.5e-51 180.79 Pfam 77-212 (293) Show / Hide 
Range on Protein: 2-123
Range on HMM: 77-212/293
Sequence Identity: 42% (58 aa)

IVMEYLPNG----DLQSLIS--QGTRF--SVEEQLNITYQILDALNYLHQRGISHRDIKPANILFDENMHP----KLIDFGMSC---ENAASSHTFCGTP
.||||...|    || ..||  ....|  | .|  .. |||| .|.|.|..|| |||.||.|||.|.|.|.    |..||| ..   .|    .||||||
MVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTP

FFMAPEIINTDNYDGKKSDIWSLAITLHVMATYVFPF
..||||.|....|.|.|.|.||. ..|. |..  .||
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPF
Kinase 92747.m00196.AA CAMK 2-173 20 6.2e-47 148.84 In-house 134-421 (425) Show / Hide 
Range on Protein: 2-173
Range on HMM: 134-421/425
Sequence Identity: 20% (60 aa)

IVM---EYLPNG----DLQSLISQG---------------TRFSVEEQLNITYQILDALNYLHQRGISHRDIKPANILFDENM-----------------
.||   || ..|    || . | .                 ||. .|   .  ||..|..|.|...| |||.|| |||.|.|.                 
MVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNN

HPKLIDFGMS--CENAA------------------------SSHTFCGTPFFMA-PEIINT-------------DNYDGKKSDIWSLAITLHVMATYVFP
  |.||||..  ..                             .|||||| .|| ||..|                |.|.|.|.||. . | .| .  .|
NIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPP

FNYQ-------------SEVQYLKDVQAKKLFFQNKAQGI------------------------MGNIIKEMLICEPKERPSSKEIIE
|.               .. . .. ... |  |  .   .                          . |. ||  .|..|.. ... .
FYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLN
Kinase 92747.m00196.AA Ciliate-E2 2-173 25 9.1e-47 158.55 In-house 111-361 (365) Show / Hide 
Range on Protein: 2-173
Range on HMM: 111-361/365
Sequence Identity: 25% (68 aa)

IVMEYLPNGDLQSLIS------------QGTRFSVEEQLNITYQILD---------------ALNYLHQRG-ISHRDIKPANILFDENMHPKLIDFGMSC
.||||.  |||...|             .  .|. .| ..|..|||.               ||.|||... | |||||| ||||     .|.||||.| 
LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSK

ENAAS----------------------------------SHTFCGTPFFMAPEIINTDNYDG--------KKSDIWSLAITLHVMATYVFPFNYQSEVQY
..  .                                   .|.|||| .|||||.|  .||.        .|.||||| ..|. | .  .||        
KYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------

LKDVQAKKLFFQNK---------------AQGIMGN---IIKE----MLICEPKERPS-SKEIIE
..  . .|. |...                . .  .   .||     || ..|..|..  ..|..
QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 92747.m00196.AA Ciliate-E2-Unclassified 2-173 27 7e-45 153.62 In-house 98-348 (352) Show / Hide 
Range on Protein: 2-173
Range on HMM: 98-348/352
Sequence Identity: 27% (68 aa)

IVMEYLPNGDLQSLISQGTR-----------------FSVEEQL-----NITYQILDALNYLHQRG-ISHRDIKPANILFDENM---HPKLIDFGMSCEN
|||||...|||.  |..                    |. .. .     ....|||..|.|||. . | |||||| |||||.|.   ..|.|||| | ..
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

AAS------------------SHTFCGTPFFM----APEIINTDNYDG---KKSDIWSLAITLHVMATYVFPFNYQSEVQ----------------YLKD
  .                  ..|||||| .|    |||..   |||.   .|.||||| . |. | .  .||..... |                ....
QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

VQAKKLFFQN--------KAQGIMGNIIK----EMLICEPKERPSSKEIIE
 ..|...|..        . .    ..|.     ||   |..|.. ..|..
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN
Kinase 92747.m00196.AA AGC 2-109 27 7.8e-45 112.68 In-house 110-291 (395) Show / Hide 
Range on Protein: 2-109
Range on HMM: 110-291/395
Sequence Identity: 27% (52 aa)

IVMEYLP---------NG-DLQSLIS---QGTRFSVEEQLNITYQ-------ILDALNYLHQ-RGISHRD-IKPANILFDENMHPKLIDFGMSCENAAS-
.||||.|          | .| . .    .  ||. |.   .. .       |. || |||. .|| ||| .|| |||.||. | || |||...|.  . 
FVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDG

----------------------------------------------------SHTFCG--TPFFMAPEIINTDNYDGKKSDIWS--L
                                                     .||||  || .|||||.      ||  |.||  |
EKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGL
Kinase 92747.m00196.AA CAMKL 2-173 32 3.6e-44 138.77 In-house 98-293 (297) Show / Hide 
Range on Protein: 2-173
Range on HMM: 98-293/297
Sequence Identity: 32% (65 aa)

IVMEYLPNGD--LQSLISQG----TRFSVEEQLNITYQILDALNYLHQRGISHRDIKPANILFDENM--HPKLIDFGMS-----C-ENAAS-SHTFCGTP
.|||| ..|.  |.  | .      |.. .|   .  ||..|.||.|..|| |||||| |||.|||.    |.||||.|     |  .     .||||.|
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP

FFMAPEIINT--DNYDGKKSDIWSLAITLHVMATYVFPFNYQSE------VQYLKDVQAKKLFFQNKAQGIM---GNIIKEMLICEPKERPSSKEIIE
 .|||||..   . |||.| ||||. ..| .| .  .||. ..        . ..  . ... ..      .    ..|. ||   |..||. ..| .
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMN
Kinase 92747.m00196.AA MARK 2-173 40 5.1e-39 125.3 In-house 79-258 (262) Show / Hide 
Range on Protein: 2-173
Range on HMM: 79-258/262
Sequence Identity: 40% (72 aa)

IVMEYLPNGDLQSLISQG--TRFSVEEQLNITYQILDALNYLHQRGISHRDIKPANILFDENM--HPKLIDFGMSCENAASS--HTFCGTPFFMAPEIIN
..||| ..|.| . | .    | . ||   |  ||. |.||.|...| |||||| ||| |||.    |.||||.| .    .   |||||| .|||||..
LIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFL

TDNYDGKKSDIWSLAITLHVMATYVFPFN--YQSEVQYLKDVQAKKLFFQNKAQGIMGNIIKEMLICEPKERPSSKEIIE
   |||.| ||||| . | .| .  |||    |....  | ... |  .  .      |.|. .|   |.|||. .|| .
KKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMK
Kinase 92747.m00196.AA ULK 2-165 23 6.2e-39 133.57 In-house 97-317 (329) Show / Hide 
Range on Protein: 2-165
Range on HMM: 97-317/329
Sequence Identity: 23% (53 aa)

IVMEYLPNGDLQSLISQGTRFSVEE----------QLNITYQILDALNYLHQRGISHRDIKPANILFDEN------------MHPKLIDFGMSCE---N-
|.||| . |||...|..  ... ..           ... .||| .. .||...| ||||||.||| ...            .. |. ||| .     . 
IIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDN

--AASSHTFC------GTPFFMAPEIIN----TDNYDGKKSDIWSLAITLHVMATYVFPFNYQSEVQYL-----KDVQA----------KKLFFQ-----
  ..  .|.       ||| .|||.|..      .|. .|.||||| . .. | .   ||. .   ..      | ..           ..| |.     
MEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGND

NKAQGIMGNIIKEMLICEPKER
..    . ..|. ||. ..|.|
PQISPECKDLIRRMLQYDEKDR
Kinase 92747.m00196.AA TKL 1-175 21 6.3e-37 128.99 In-house 114-364 (364) Show / Hide 
Range on Protein: 1-175
Range on HMM: 114-364/364
Sequence Identity: 21% (55 aa)

MIVMEYLPNGD-LQSLISQGTRFSVEEQLNITYQILDALNYLHQ--------RGISHRDIKPANILFDENMH--------------PKLIDFGMSCENAA
.||||| |.|. |  |.        .  ... ..|  ..||||.        ..| |||.|..||| |||..              .|. ||| | ..  
CIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQ

S----------------------SHTFCGTPFFMAPEIINTDNYDG---------------KKSDIWSLAITLHVMAT--YVFP-FNYQSEV------QY
|                      ..| |||| .||||... ....                .|.|..| .| |  ..|   ..  ..| ...      ..
SGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEM

LKDVQ--AKKLFFQ------------NKAQGIMGNIIKEMLICEPKERPSSKEIIEMI
.. |    ...               . .   | .....    .|..||| .||.. .
FMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 92747.m00196.AA ULK 2-177 24 1.8e-36 126.93 In-house 94-324 (324) Show / Hide 
Range on Protein: 2-177
Range on HMM: 94-324/324
Sequence Identity: 24% (56 aa)

IVMEYLPNGDLQSLIS---------QGTRFSVEEQLNITYQILDALNYLHQRGISHRDIKPANILFDEN------------MHPKLIDFGMSCE------
|.||| . |||...|           . |.| .| ... .||. .. .||...| ||||||.|||  ..             . |. ||| .        
IIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNM

NAASSHTFC------GTPFFMAPEIIN----TDNYDGKKSDIWSLAITLHVMATYVFP---FNYQSEV----QYLKD-------VQAKKLFFQ-----NK
..   .|..      ||| .|||.|..      .|. .|.||||| . .. | .   |     .....    . ..        .. ... |.     .|
EQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPK

AQGIMGNIIKEMLICEPKERPSSKEIIEMIEQ
    . ..|. ||. ..|.| |  ||...   
ISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 92747.m00196.AA STE 2-170 25 5.1e-35 121.13 In-house 114-350 (359) Show / Hide 
Range on Protein: 2-170
Range on HMM: 114-350/359
Sequence Identity: 25% (62 aa)

IVMEYLPNGDLQSLISQ--GTRFSV-----------EEQL-NITYQILDA-LNYLHQRGISHRDIKPANILFDENMHPKLIDFGMSCENAA---------
|.|||...| | ..| .  |. ..            |.|.  |..||| . |.|||. .| ||||||||||.      ||.||| .   .          
ICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNN

----------SSHTFCGTPFFMAPEIINT-----DNYDGKKSDIWSLAITLHVMATYVFPFNYQSEVQYLKDVQAKKLFFQ---------NKAQGIMG--
           . ||.||| .||||.|.      |.  . |.||||| .|.  |||   |.   .  . .   . ..  .|         ..   .    
IIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHL

------------------------NIIKEMLICEPKERPSSKE
                        . |.  |. .|..||....
SQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 92747.m00196.AA S_TKc 1-179 23 7.6e-22 79.81 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-179
Range on HMM: 1-231/231
Sequence Identity: 23% (60 aa)

M--------------------------------------------------------------IVMEYLPN--GDLQSLISQGTR------FSVEEQLNI
                                                               .||||...  ||| ..| .  |      |.  .   .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

TYQILDALNYLHQRGISHRDIKPANILFDENMHPKLIDFGMSCENAASSHTFCGTPFFMAPEIINTDNYDGKKSDIWSLAITLHVMATYVFPFNYQSEVQ
.|||..||.|.|..|| |||.||.|||.||  | |..|||....     .||||||..||||..    |...|.|.||. ..|  |..   ||    . .
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQM

YLKDVQAKKLFFQNKAQGIMGNIIKEMLICEPKERPSSKEIIE-----MIEQYC
 .| .           .     .|. .|  .|..||.  |. .     .. .. 
MFKKIG---------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 92747.m00196.AA Pkinase_Tyr 1-72 32 1.1e-08 30.09 Pfam 83-158 (270) Show / Hide 
Range on Protein: 1-72
Range on HMM: 83-158/270
Sequence Identity: 32% (25 aa)

MIVMEYLPNGDLQSLISQ----GTRFSVEEQLNITYQILDALNYLHQRGISHRDIKPANILFDENMHPKLIDFGMS
.||||| |.||| .   .    . ...... |.. .|| ....||..... |||.   |.| .||.. |  |||..
YIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 92747.m00196.AA TyrKc 1-175 18 1.8e-08 -85.68 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-175
Range on HMM: 1-280/280
Sequence Identity: 18% (52 aa)

M--------------------------------------------------------------------------IVMEYLPNGDLQSLISQGTR-FSVE
                                                                           ||||| |.|||.. .    . ....
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

EQLNITYQILDALNYLHQRGISHRDIKPANILFDENMHPKLIDFGMSCENAAS-------SHTFC----GTP-----FFMAPEIINTDNYDGKKSDIWSL
. |.. .|| .  .|||.... |||.   |.| .|| . |  |||.| .           .        |.        |||| ||.  .   |||.|| 
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKSDVWSF

AITLHVMATYVFPFNYQ------SEVQYLKDVQAK-KLFFQNK--------AQGIMGNIIKEMLICEPKERPSSKEIIEMI
 ...  . ||  .  .       |  . ...|..   .             .   | .|.|.    .|..||. .||.| .
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 92747.m00196.AA Pkinase 153-175 32 1.478244 3.05 Pfam 269-293 (293) Show / Hide 
Range on Protein: 153-175
Range on HMM: 269-293/293
Sequence Identity: 32% (8 aa)

IIKEMLICEPKERPSSKEIIEM--I
.|| .|   ||.||. ..| .   .
FIKWCLCKDPKKRPTAEQILQHPWF