Gene 88953.m00048 (T.vaginalis)

88953.m00048

Species: T.vaginalis
Alias: TvagK0926, 88953.m00048
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: AMPK

Sequence

Name Sequence Type Origin Length Description Download
88953.m00048.AA Protein None 392 None Fasta, JSON
88953.m00048.kin_dom Protein Kinase Domain None 191 None Fasta, JSON

Protein domain

Protein domains of 88953.m00048.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 88953.m00048.AA AGC 193-260 25 1.4e-32 80.26 In-house 292-395 (395) Show / Hide 
Range on Protein: 193-260
Range on HMM: 292-395/395
Sequence Identity: 25% (27 aa)

GVILYRMLTGAYPFEDDSSS----------ELFTNIL------SMKPIIP----------SQISNDAKNLLTRMLTKATYERIT----------FEEIME
|...| ||||  || .|.            |.| .|.      . |. .|          ...|..||.|....|.|   .|..          .|||..
GCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKN

HPFF
||.|
HPWF
Kinase 88953.m00048.AA AMPK 189-260 41 5.7e-31 89.23 In-house 183-254 (254) Show / Hide 
Range on Protein: 189-260
Range on HMM: 183-254/254
Sequence Identity: 41% (30 aa)

VWRCGVILYRMLTGAYPFEDDSSSELFTNILSMKPIIPSQISNDAKNLLTRMLTKATYERITFEEIMEHPFF
.| |||||| || |  ||.|.. ..|. .|.. .. ||. .|..||.|. .||..   .|||...|..||.|
IWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 88953.m00048.AA SAK 12-260 26 5.2e-29 95.73 In-house 1-254 (254) Show / Hide 
Range on Protein: 12-260
Range on HMM: 1-254/254
Sequence Identity: 26% (67 aa)

YEFIKLLDTTDTYELWKARSTKLMPFVLIRVLPKQYIDH----NRYGEEIKIHSLANFPFTSKFYQYFEEGELTFVVMEYLNDENLEEYISNNSKI-NEE
|.  .||        ..|.. .    | |... |. . .    .|  .|..||.    |   . |.|||.    ..|.|      .. |. .  .   ||
YQVQHLLGKGGFACVYRAKCIHTHQEVAIKMIDKKLMQKTGMVQRVRNEVEIHCQLKHPSILELYNYFEDNNYVYLVLEMCHNGEMHRYMKHRMRPFTEE

QARIWFSQIISTLNYLDTQFQVYHGNLEACCFSLADSNALKLFDFEYCHYLDS-SVKCMTSRCHPFYLSPEEIKNESNPLATTVWRCGVILYRMLTGAYP
 ||  . ||.  . ||     . |  |      |.    .|. ||     |     | .|    | |.||| .   .  | . ||  | .|| .|.|  |
EARHFMHQIVIGMLYLHS-HGIMHRDLTLSNILLTRDMHCKIADFGLATQLKMPHEKHYTMCGTPNYISPEIATRTAHGLQSDVWSLGCMLYTLLIGRPP

FEDDSSSELFTNILSMKPIIPSQISNDAKNLLTRMLTKATYERITFEEIMEHPFF
|. |.  .    ..    |.|. .| .|. |. .|| |   |||| . .. ||| 
FDTDAVKNTLNKVMMAEYIMPAHLSMEAQDLIHKMLRKNPHERITLSTVLCHPFM
Kinase 88953.m00048.AA Ciliate-E2-Unclassified 66-260 24 5.8e-27 90.57 In-house 81-352 (352) Show / Hide 
Range on Protein: 66-260
Range on HMM: 81-352/352
Sequence Identity: 24% (66 aa)

PFTSKFYQYFEEGELTFVVMEYLNDENLEEYISNNSK-----------------INEEQAR-----IWFSQIISTLNYLDTQFQVYHGNLEACCFSLADS
||  |.. .|.  .  . ||||... .|..||....|                 . |.||.      .| ||.. |.||  .  . | ..      . ..
PFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNN

N---ALKLFDFEYCHYLDSSVKC---------------MTSRC-HPFYL----SPEEIKNESNP----LATTVWRCGVILYRMLTGAYPFEDDSSSE---
.    .|. ||  . .......|               |...|  | |.    .|| .... .      .  .| .||||| ||.| |||.| .. .   
GKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQ

-------------LFTNILSM------KPI--IPSQISNDAKNLLT----RMLTKATYERITFEEIMEHPFF
             |. ||.         |   || ..|. ||....    .|| |   .|||||.|..||.|
LITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 88953.m00048.AA CAMK 138-260 21 6.5e-27 83.16 In-house 228-425 (425) Show / Hide 
Range on Protein: 138-260
Range on HMM: 228-425/425
Sequence Identity: 21% (42 aa)

FSLADSNA-LKLFDFEYCHYLDSSV------------------------KCMTSRCHPFYLS-PEEIKN--------------ESNPLATTVWRCGVILY
| .  .|. .|. ||    ..|..                         |. |.   | | . || ..               .  . .. .| ||||||
F-D-WNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILY

RMLTGAYPFEDD-------------SSSELFTNILSMKPI-IPSQ---------------ISND--------AKNLLTRMLTKATYERITFEEIMEHPFF
 ||.| .||..|             . .||| .|.. |   .|..               ||..        .|.|. .||..   .|.| |....||..
IMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 88953.m00048.AA CAMKL 189-260 32 1.6e-25 78.27 In-house 219-297 (297) Show / Hide 
Range on Protein: 189-260
Range on HMM: 219-297/297
Sequence Identity: 32% (26 aa)

VWRCGVILYRMLTGAYPFEDDSSS---------ELFTNILSMKPIIPSQISNDAKNLLTRMLTKATYERITFEEIMEHPFF
.| |||||| |..|..||.||. .         .. ....  .| |....| |...|. .||..   .|.| ..||.||..
IWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 88953.m00048.AA MARK 189-260 43 7.9e-25 78.24 In-house 189-262 (262) Show / Hide 
Range on Protein: 189-260
Range on HMM: 189-262/262
Sequence Identity: 43% (32 aa)

VWRCGVILYRMLTGAYPFEDDS--SSELFTNILSMKPIIPSQISNDAKNLLTRMLTKATYERITFEEIMEHPFF
.| .||.|| |..| .||..|.    ||. .||. |. ||. .| ...||. |.||    ||.| ||||.||..
IWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 88953.m00048.AA ULK 189-260 28 3.6e-21 70.7 In-house 239-329 (329) Show / Hide 
Range on Protein: 189-260
Range on HMM: 239-329/329
Sequence Identity: 28% (26 aa)

VWRCGVILYRMLTGAYPFEDDSSSELF-----TN----------ILSMKPIIP-----SQISNDAKNLLTRMLTKATYERITFEEIMEHPFF
.|  |.|.| ||.| .||.    ....      .          | . .. .|      |||.. |.|. |||..   .||..||. .||.|
IWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 88953.m00048.AA ULK 189-260 29 7.4e-21 70.78 In-house 235-324 (324) Show / Hide 
Range on Protein: 189-260
Range on HMM: 235-324/324
Sequence Identity: 29% (27 aa)

VWRCGVILYRMLTGAYPFEDDSSSELFT---NILSM----------KPIIPS------QISNDAKNLLTRMLTKATYERITFEEIMEHPFF
.|  |.|.| ||.| |||. .  ....    . . .          .|| .       .||.. |.|. |||..   .||..||| .||.|
IWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 88953.m00048.AA Pkinase 170-260 22 1.8e-19 69.93 Pfam 175-293 (293) Show / Hide 
Range on Protein: 170-260
Range on HMM: 175-293/293
Sequence Identity: 22% (27 aa)

PFYLSPEEIK-NESNPLATTVWRCGVILYRMLTGAYPFEDD------SSSELFTNILSMKPIIPSQIS---------------------NDAKNLLTRML
|.|..|| |. ..  . .  .| ||.||| ||.|  || ..      .  ... .|.. ..  ... .                      ..| .....|
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

TKATYERITFEEIMEHPFF
.|  ..|.|.|.|..||.|
CKDPKKRPTAEQILQHPWF
Kinase 88953.m00048.AA Ciliate-E2 146-260 20 3.7e-19 62.4 In-house 195-365 (365) Show / Hide 
Range on Protein: 146-260
Range on HMM: 195-365/365
Sequence Identity: 20% (37 aa)

LKLFDFEYCHYLDSS----------VKCMTSR-----------------------CHPFYLSPEEIKNES---------NPLATTVWRCGVILYRMLTGA
.|. || .. ..| .           ..|  .                       . | |..|| .....            .  .| .|||||.||.| 
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

YPFEDDSSSELFTNILSMKPIIP------------------SQISNDAKNLLTR----MLTKATYERIT-FEEIMEHPFF
.||        . .|.  |  .|                   ..|...|.|. .    || |   .||| .|.|..||.|
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 88953.m00048.AA S_TKc 12-260 24 1.3e-17 65.78 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-260
Range on HMM: 1-231/231
Sequence Identity: 24% (64 aa)

YEFIKLLDTTDTYELWKARSTKLMPFVLIRVLPKQYIDHNRYGEEIKIHSLANFPFTSKFYQYFEEGELTFVVMEYLND--ENLEEYISNNSK------I
||.....      . .|.| .|    | | ...      ..   ||.|..  . |.  |.| .|.. .  ..||||..    .| .|| .. .      .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

NEEQARIWFSQIISTLNYLDTQFQVYHGNLEACCFSLADSNALKLFDFEYCHYLDSSVKCMTSRCHPFYLSPEEIKNESNPL-ATTVWRCGVILYRMLTG
.| .|| .. ||.. |.|.  . .. |  |      | .   .|. ||  .  |      .|    |.|..|| .   .    .  .| ||.||| ||.|
PE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

AYPFEDDSSSELFTNILSMKPIIPSQISNDAKNLLTRMLTKATYERITFEEIME-------HPFF
  ||.     ..| .|.          | .||... ..|.|   .|.|  |...       ||.|
YPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 88953.m00048.AA MARK 56-122 30 7e-12 35.29 In-house 49-120 (262) Show / Hide 
Range on Protein: 56-122
Range on HMM: 49-120/262
Sequence Identity: 30% (22 aa)

EIKIHSLANFPFTSKFYQYFE--EGEL-TFVVMEYLNDENLEEYISNN--SKINEEQARIWFSQIISTLNYL
||.|... ..|   |.....|  . .  ....|||    .| .|| .    .. || ||  |.||.| .||.
EIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYC
Kinase 88953.m00048.AA CAMKL 56-122 30 2.4e-11 32.31 In-house 62-143 (297) Show / Hide 
Range on Protein: 56-122
Range on HMM: 62-143/297
Sequence Identity: 30% (25 aa)

EIKIHSLAN---FPFTSKFYQYFEEGEL------TFVVMEYLNDEN--LEEYISNN----SKINEEQARIWFSQIISTLNYL
||.|... |    |   |.|. .|  |        . ||||    .  | .|| ..     .. |..||  | ||.| .||.
EIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYC
Kinase 88953.m00048.AA AMPK 82-122 39 1.6e-10 27.55 In-house 76-116 (254) Show / Hide 
Range on Protein: 82-122
Range on HMM: 76-116/254
Sequence Identity: 39% (16 aa)

FVVMEYLNDENLEEYISNNSKINEEQARIWFSQIISTLNYL
|.||||     | .||  . ...|..|.  | |||| . |.
FMVMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYC
Kinase 88953.m00048.AA CAMK 70-122 19 1e-08 23.44 In-house 102-195 (425) Show / Hide 
Range on Protein: 70-122
Range on HMM: 102-195/425
Sequence Identity: 19% (18 aa)

KFYQYFEEGE-------------------LTFVVM---EYLNDE----NLEEYISNNSK---------------INEEQARIWFSQIISTLNYL
|.|...| ..                     . ||   ||         | .||  ...               ..|..|| .| ||.| ..|.
KLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYC
Kinase 88953.m00048.AA Ciliate-E2 64-122 22 1.4e-08 25.52 In-house 90-176 (365) Show / Hide 
Range on Protein: 64-122
Range on HMM: 90-176/365
Sequence Identity: 22% (20 aa)

NFPFTSKFYQYFE--EGELTFVVMEYLNDENLEEYISNN-----------SKINEEQARIWFSQIIS---------------TLNYL
|.|.  |.| .|.    .  . ||||..  .|..|| ||            ...|....  . ||..                |.||
NHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYL
Kinase 88953.m00048.AA ULK 70-122 29 3e-06 17.74 In-house 82-146 (329) Show / Hide 
Range on Protein: 70-122
Range on HMM: 82-146/329
Sequence Identity: 29% (19 aa)

KFYQYFEEGEL--TFVVMEYLNDENLEEYISNN----------SKINEEQARIWFSQIISTLNYL
|.| .||.     .. .||| |. .||.||..|           ...|..|.. | ||.. . .|
KLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKEL
Kinase 88953.m00048.AA ULK 70-122 29 8e-06 16.77 In-house 79-142 (324) Show / Hide 
Range on Protein: 70-122
Range on HMM: 79-142/324
Sequence Identity: 29% (19 aa)

KFYQYFEEGEL--TFVVMEYLNDENLEEYISNN---------SKINEEQARIWFSQIISTLNYL
|.| .||.     .. .||| |. .||.|| .|          ...|..|.. | ||.. . .|
KLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKEL
Kinase 88953.m00048.AA Pkinase 70-122 26 1.1e-05 21.19 Pfam 64-124 (293) Show / Hide 
Range on Protein: 70-122
Range on HMM: 64-124/293
Sequence Identity: 26% (16 aa)

KFYQYFEEGELTFVVMEYLNDE----NLEEYIS--NNSKI--NEEQARIWFSQIISTLNYL
..| .||..    .||||..       | .|||  .. ..   |.... .. ||.. |.|.
RLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYC
Kinase 88953.m00048.AA AGC 42-122 18 1.8e-05 8.51 In-house 37-169 (395) Show / Hide 
Range on Protein: 42-122
Range on HMM: 37-169/395
Sequence Identity: 18% (25 aa)

VLPKQY---------IDHNRYG----------EEIKIHSLAN----------FPFTSK-FYQYFEEGEL--TFVVMEYLN----------DENLEEYIS-
|| |..         ..|.             || .| ...|           ||  |  .  |.  .    . ||||..          .  |  ..  
VLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQG

--NNSKINEEQARIWFSQ-------IISTLNYL
  .. . .||.||.....       |.. | ||
RRKEGRFDEERARFYAAEMQKICGCIVLALEYL
Kinase 88953.m00048.AA TyrKc 37-260 13 0.000705 -159.92 SMART 1-280 (280) Show / Hide 
Range on Protein: 37-260
Range on HMM: 1-280/280
Sequence Identity: 13% (40 aa)

FVLIRVL---------------------PKQYIDHNRYGEEIKIHSLA--NFPFTSKFYQYFEEG-------ELTFVVMEYLNDENLEEYISNNSK-INE
 .|...|                      | .  .    .|..| .    . |   ..| .  ..       |  ..||||    .| .|. .. . .. 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCM

EQARIWFSQIISTLNYLDTQFQV----------YHGNLEACCFSLADSNALKLFDFEYCHYLDSS--------VKCMTS--RCHP----FYLSPEEIKNE
..   .  || .  .||  .  .          .. |.             |  ||  . ....         .. ...   ..       ..|| |.  
KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

SNPLATTVWRCGVILYRMLTGAYPFEDD------SSSELFTNILSM-KPIIPSQ--------ISNDAKNLLTRMLTKATYERITFEEIMEHPFF
    .. ||  || .. ..|   .   .      | .|.. .. .   . .|           . .  .. ..       .| ||.||  | .|
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
UBA_CAMKL 88953.m00048.AA UBA_CAMKL 278-313 20 8.5e-05 15.6 In-house 3-41 (41) Show / Hide 
Range on Protein: 278-313
Range on HMM: 3-41/41
Sequence Identity: 20% (8 aa)

DILRQLERV--GYNKADVVADLKAKLF-TEKTAAYNILL
.|.....    |... ...  |.   .  . ||.| .||
EIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL