Gene 80597.m00004 (T.vaginalis)

80597.m00004

Species: T.vaginalis
Alias: 80597.m00004, TvagK0824
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
80597.m00004.AA Protein None 281 None Fasta, JSON
80597.m00004.kin_dom Protein Kinase Domain None 181 None Fasta, JSON

Protein domain

Protein domains of 80597.m00004.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 80597.m00004.AA Ciliate-E2 14-182 14 5.5e-13 40.9 In-house 1-292 (365) Show / Hide 
Range on Protein: 14-182
Range on HMM: 1-292/365
Sequence Identity: 14% (44 aa)

LTFKRVICDTKYGKVFLV-QWNKYR----------------------ELYSLERVDVR--HFEERQTDVIKNFY----------------HTNIINIYRY
  | ..|.   .|.|... .|.. .                       .| ....  .   . ..  ....                   | |||..| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

WY--REKYVYILMDYCPV-DLYRLVTVQ-----------GVISEQKFIQYSFEMLQ---------------SLKILHDKK-FCHGNIRPSKFLIDRYNHI
..   ....|. |.||   ||. .   .           . ..|.. .... . ||                |. || |.  .| .| |.  |.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RICDFSNA-------------------------------------------------VSASEVSESEF--------QKMKLDDIWSLGETFYYMLTG
 |.|| ..                                                   | |. ...         .  .  |||||| ..|.||.|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG
Kinase 80597.m00004.AA S_TKc 14-240 20 2.5e-12 3.98 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-240
Range on HMM: 1-231/231
Sequence Identity: 20% (52 aa)

LTFKRVICDTKYGKVFLVQWNKYRELYSLERVDVRHFEERQTDVIKNFYHTNIINIYRYWYREKYVYILMDYCPV---DLYRLVTVQGV------ISEQK
 .. |.|    .|||......|  ... . ...     .|  .. |.  | ||...| ...  ...|. |.||.    ||...   .|       ..|  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

FIQYSFEMLQSLKILHDKKFCHGNIRPSKFLIDRYNHIRICDFSNAVS-----------ASEVSESEFQKMK-LDDIWSLGETFYYMLTGLL----ISDL
   |  .... |. .|.....|  . |.  |.|.  || ||||  |             | ||     .  |   |.||.| ..| ||.|      .  .
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQLTTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMM

YMTKKDAKSRNFANVKYPSSIPTEIAMMVSCCLQCKESNSLTIDDILR-------CSIY
.   .                . |   ... |||   .. .|. ..|.           
FKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 80597.m00004.AA Ciliate-E2-Unclassified 15-184 18 1.3e-10 33.09 In-house 2-268 (352) Show / Hide 
Range on Protein: 15-184
Range on HMM: 2-268/352
Sequence Identity: 18% (50 aa)

TFKRVICDTKYGKVFLVQWNKYRELY----------SLERVDVRH-----FEERQTDVIK----------------NFYHTNIINIYRYWYREKYVYILM
.. ..|.   .|||...| .|   .|          .  .  ...     .|. .   .|                |..| .|.. . .   ....|| |
KIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

DYC------------------PVDLYRLVTVQGVISEQKFI-----QYSFEMLQSLKILHDKK-FCHGNIRPSKFLIDRYN---HIRICDFSNAV-----
.||                    ||..    .  ..||. .     .|  . || |. || |. ..| .| |.  |.|  .   .|.|.||...      
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

-----------------------------S---ASEVSES-EFQKM--KLDDIWSLGETFYYMLTGLL
                             .   | || .. .  ..  .  ||||||  .|.||.| .
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYY
Kinase 80597.m00004.AA CMGC 59-150 14 2.3e-09 25.96 In-house 76-251 (513) Show / Hide 
Range on Protein: 59-150
Range on HMM: 76-251/513
Sequence Identity: 14% (26 aa)

KNF-----------------YHTNIINIYRYWYREK-----------------YVYILMDYCPVDLYRLVTVQG---------VISEQK-----------
|..                  | ||...| . |...                 ..|. ..|.. |||..   .            || .           
KHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPH

-FIQYS------FEMLQSLK--ILHDKK--FCHGNIRPSKFLIDR--------------------YNHIRICDFSNA
    ..      . .|..||   .| ..  ..|  . |.  ||.                       ...|||| .|
NIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLA
Kinase 80597.m00004.AA Pkinase 25-126 19 4.5e-09 33.18 Pfam 12-131 (293) Show / Hide 
Range on Protein: 25-126
Range on HMM: 12-131/293
Sequence Identity: 19% (23 aa)

YGKVFLVQWNKYRELYSLERVDVRHFEERQT---------DVIKNFYHTNIINIYRYWYREKYVYILMDYCPV-----DLYRLVT--VQGVI--SEQKFI
.|.|.. .. ...... . ....|| .. .           . |.. | ||. .|.........|. |.||.      ||.....   .|..  ||.  .
FGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECK

QYSFEMLQSLKILHDKKFCH
 |  ..|. |. .|.....|
FYMYQILRGLEYCHSMGIIH
Kinase 80597.m00004.AA Ciliate-E1 49-163 19 1.1e-08 24.84 In-house 39-169 (202) Show / Hide 
Range on Protein: 49-163
Range on HMM: 39-169/202
Sequence Identity: 19% (26 aa)

HFEERQTD-VIKNFY-HTNIINIYRYWYREKY-VY-ILMDYCPVDLYRLVT-------------VQGVISEQKFIQYSFEMLQSLKILHDKKFCHGNIRP
..| .. . . | |  . .||.|. | . ... .. |....|   |..  .              |.  ..|...|  | ... | .||.....|..| |
QDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKP

SKFLIDRYNHIRICDFSNAVSASEVSESEFQK
.. ||....   .|||. .    . .... |.
QNILINNQGNYVYCDFGISKFLKNNQNQQCQY
Kinase 80597.m00004.AA ROCK 76-147 31 2.4e-08 24.17 In-house 71-142 (263) Show / Hide 
Range on Protein: 76-147
Range on HMM: 71-142/263
Sequence Identity: 31% (23 aa)

EKYVYILMDYCP-VDLYRLVTVQGVISEQKFIQYSFEMLQSLKILHDKKFCHGNIRPSKFLIDRYNHIRICDF
..|.|. ||| |  ||  |..    ..|.  . |  |.   |  .|   | |  ..|   |.|.| |... ||
DRYLYMVMDYMPGGDLVNLMSNYD-VPEKWARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADF
Kinase 80597.m00004.AA GIN4 52-150 24 9.7e-08 20.34 In-house 82-182 (293) Show / Hide 
Range on Protein: 52-150
Range on HMM: 82-182/293
Sequence Identity: 24% (25 aa)

ERQTDVIKNFYHTNIINIYRYWYREKYVYILMDYCPV-DLYRLVTVQGVISEQKFIQYSFEMLQSLKILHDKKFCHGNIRPSKFLIDRYNH-IRICDFSN
||   ..|   |.|.. .|  |  .. .|....|    .|. ..  .| . |.  |.|   ..  .   |    ||  ..|   |.|. .. |.| ||  
EREIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFGM

A
|
A
Kinase 80597.m00004.AA Ciliate-E3 72-147 28 1.9e-07 19.63 In-house 72-150 (202) Show / Hide 
Range on Protein: 72-147
Range on HMM: 72-150/202
Sequence Identity: 28% (23 aa)

YWYREKYVYILMDYCPV-DLYRLVTVQGVISEQKFIQYSFEMLQSLKILHDKKFCHGNIRPSKFLIDRYN---HIRICDF
|    |   | ..|| . |||  .  | . ...  ..   ...|.. ..| |.  |. | |. .|.|  |    |.||||
YDQQNKMIFIVQEYCSNGDLYHYIK-QQNKTQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKICDF
Kinase 80597.m00004.AA Ciliate-C3 106-147 38 5e-07 21.57 In-house 99-140 (140) Show / Hide 
Range on Protein: 106-147
Range on HMM: 99-140/140
Sequence Identity: 38% (16 aa)

IQYSFEMLQSLKILHDKKFCHGNIRPSKFLIDRYNHIRICDF
.| |  .|| .  ||.    || |..|  ||   ..|.| ||
LQISKQILQAIDYLHEHNIVHGDIKFSNILINSKDEIKIIDF
Kinase 80597.m00004.AA MELK 56-147 23 6.7e-07 19.28 In-house 49-141 (254) Show / Hide 
Range on Protein: 56-147
Range on HMM: 49-141/254
Sequence Identity: 23% (22 aa)

DVIKNFYHTNIINIYRYWYREKYVYILMDYCP-VDLYRLVTVQGVISEQKFIQYSFEMLQSLKILHDKKFCHGNIRPSKFLIDRYNHIRICDF
| .||. | .|  .| |   |. ....|.|||  ...  .  |  ..|.   ..  ... ..  .| . . | ...|  .|.| . |... ||
DALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDF
Kinase 80597.m00004.AA KHS 57-147 27 7.9e-07 18.85 In-house 49-140 (258) Show / Hide 
Range on Protein: 57-147
Range on HMM: 49-140/258
Sequence Identity: 27% (25 aa)

VIKNFYHTNIINIYRYWYREKYVYILMDYCPV-DLYRLVTVQGVISEQKFIQYSFEMLQSLKILHDKKFCHGNIRPSKFLIDRYNHIRICDF
..|.  |.||.  .  . |.. ..| |.||    |  .  | | .|| .    . | || |. || ..  |  |.    |.  . .... ||
MMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGPLSELQIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADF
Kinase 80597.m00004.AA TyrKc 14-239 13 9e-06 -129.23 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-239
Range on HMM: 1-280/280
Sequence Identity: 13% (40 aa)

LTFKRVICDTKYGKVFLVQWNKYRELYSLERV-------DVRHFEE--RQTDVIKNF--YHTNIINIYRYWYRE-------KYVYILMDYCPV-DLYRLV
.|.....    .|.|.. .|.        . |       |    |.  |   . ...   | ||...| .   .       . ..|.| |.|  ||    
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

TVQGV-ISEQKFIQYSFEMLQSLKILHDKKFCHGNIRPSKFLIDRYNHIRICDFSNAVSASEV-----SESEFQKMK--LDD------------------
   .  .. ........   .    ||.|.. |  .     |... ....|.||  .    .      |..   |..    .                  
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

---------------IWSLGETFYY------MLTGLLISDLYMTKKDAKSRN-----FANVKYPSSIPTEIAMMVSCCLQCKESNSLTIDDILRCSI
               | ..|.. |.      |    .| ..   .   .  |     |         |.|. .. ..| . . ..  |  .| .  .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF------VCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase 80597.m00004.AA Pkinase 168-182 53 0.479166 4.78 Pfam 194-208 (293) Show / Hide 
Range on Protein: 168-182
Range on HMM: 194-208/293
Sequence Identity: 53% (8 aa)

DIWSLGETFYYMLTG
|.||.| ..|.||.|
DMWSCGCILYEMLCG